Clinical trials: Personality Disorder
Borderline Personality Disorder, Oxytocin
Interplay Between Oxytocin and Cortisol During Stress in Borderline Personality Disorder
This study aims to determine the feasibility and preliminary data on the interaction between oxytocin and cortisol during stress in borderline personnality disorder.
- Trial name
- OXT-CORT-BPD (NCT05357521)
- Testing
- stress test
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Geneva, Switzerland
Pulmonary Function; Newborn, Abnormal, Infant Wheeze
Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function
Vitamin C supplementation (500 mg per day) given to pregnant women who can not quit smoking will improve the pulmonary function tests in their offspring measured at 3 months of age.
- Conditions
- Pulmonary Function; Newborn, Abnormal, Infant Wheeze, In-utero Nicotine, Second Hand Smoke
- Trial name
- VCSIP (NCT01723696)
- Testing
- Vitamin C +prenatal vitamin
- Where
- 2 sites in United States
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Personality Disorders
Biological Effects of Schema Therapy
Background: The major aim of this study is to compare the effects of emotion focused (experiential) and cognitive interventions of schema therapy (ST) on emotion regulation deficits in patients with borderline personality…
- Trial name
- BE-ST (NCT06367907)
- Testing
- schema therapy
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Jena University Hospital
Conduct Disorder, Anti-Social Behavior
Multisite Prevention of Conduct Problems (Fast Track)
The primary aim of this project is to evaluate the effects of a comprehensive intervention to prevent severe and chronic conduct problems in a sample of children selected as high-risk when they first entered school.
- Trial name
- NCT01653535
- Testing
- Fast Track
- Where
- United States
- Volunteers
- 891 people, healthy volunteers welcome
- Sponsor
- Duke University
Self Injurious Behavior Without Suicidal Intent, Self-Injurious Behavior
Genetics of Self-injurious Behaviour
Nonsuicidal Self-Injury (NSSI) is being increasingly regarded as a separate psychiatric disorder. Since the latest Diagnostic and Statistical Manual of Mental Disorders - DSM-5 from 2013 defined NSSI as a separate diagnosis under…
- Trial name
- NCT05563324
- Testing
- DNA extraction and genotyping of candidate genetic polymorphisms, self-assessment questionnaires
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Maribor
Schizophrenia Disorders
An Integrated Neurophysiological Approach Toward the Early Detection of Psychiatric Disorders
Schizophrenia (SCZ) is a severe neuropsychiatric disorder characterized by cognitive decline, social withdrawal, and positive symptoms such as hallucinations and delusions.
- Trial name
- NCT06886945
- Testing
- Audio-Visual Perceptual Tasks
- Where
- Italy
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Borderline Personality Disorder
Methylation Status of BDNF Gene After Dialectical Behavior Therapy in BPD
Borderline personality disorder (BPD) is a chronic and debilitating syndrome associated with considerable morbidity, mortality, and high rates of medical and psychiatric utilization services.
- Trial name
- NCT02134223
- Testing
- Dialectical behavior therapy, Treatment as Usual: any other drug or psychotherapy offered to participants, except DBT
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Healthy
SwissGut - The Healthy Swiss Microbiome
Objective: This study is designed to address the complex interplay between the gut microbiome, environmental factors, and inflammatory diseases, with a specific emphasis on serving as a healthy cohort for several related…
- Trial name
- SwissGut (NCT06191224)
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Benjamin Misselwitz
Female, Borderline Personality Disorder
Reactivity of Patients With Borderline Personality Disorder to an Ecological Interpersonal Stress
Use lay language. According to the World Health Organization 1 death by suicide occurs every 40 seconds, leading suicide prevention to one of the public health priority.
- Trial name
- ROI (NCT03602521)
- Testing
- Interpersonal stress
- Where
- France
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Personality Disorder
An Evolutionarily Informed Conceptualization of Personality Pathology
The purpose of this study is to explore the reliability of a new evolutionarily-informed model for conceptualizing personality pathology.
- Trial name
- EIC-PP (NCT06623838)
- Testing
- Evolutionarily informed case conceptualization
- Where
- Italy
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Tages Onlus
Substance Use Disorders, Adolescent Behavior
The Canadian Underage Substance Use Prevention Trial
Despite having made some strides with respect to reducing adolescent drinking rates, illicit substance use and substance use disorders (SUDs) remain significantly above national targets for health promotion and disease prevention…
- Conditions
- Substance Use Disorders, Adolescent Behavior, Adolescent Development
- Trial name
- CUSP (NCT04198974)
- Testing
- PreVenture Training (PTtT), PreVenture Training+Implementation Facilitation
- Where
- 4 sites in Canada
- Volunteers
- 12,500 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Mental Health Wellness 1
Evaluation of A Mindfulness Resiliency Training Program for Refugees Living in Jordan
To estimate the efficacy of a structured, scalable and replicable psychosocial intervention targeting refugees living in Jordan, Amman who have been forced to flee their homes due to regional conflicts.
- Conditions
- Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Mental Health Wellness 1, War-Related Trauma
- Trial name
- NCT03760627
- Testing
- Refugees Mindfulness Resiliency Training, Mindfulness Resiliency Training
- Where
- Jordan
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Yale University
Self-esteem, Personality
Psychological Assessment of Adults Seeking Orthodontic Treatment
Is their a association between the objective and subjective severity of a malocclusion, quality of life and self-esteem/personality (as modifier between objective/subjective severity and quality of life (cfr study Agou et al.…
- Conditions
- Self-esteem, Personality, Quality of Life, Malocclusion
- Trial name
- NCT01475773
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Schizotypal Personality Disorder, Personality Disorders
Pharmacology of Cognition in Schizotypal Personality Disorder
This study will determine the effectiveness of guanfacine in improving cognitive and functional impairments in schizotypal personality disorder.
- Trial name
- NCT00353379
- Testing
- Guanfacine
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Anxiety Sensitivity, Hopelessness
The UniVenture Program
UniVenture is a research partnership with one common goal: to adapt, test, and begin sharing an effective, sustainable, targeted wellness program to tackle the timely social issue of heavy drinking and other substance misuse on…
- Conditions
- Anxiety Sensitivity, Hopelessness, Sensation Seeking, Impulsivity
- Trial name
- NCT05383989
- Testing
- UniVenture Hopelessness manual, UniVenture Anxiety Sensitivity manual, UniVenture Sensation Seeking manual
- Where
- 5 sites in Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Sherry Stewart
Borderline Personality Disorder
The Effects of Methylphenidate on Symptomatology in Individuals With Borderline Personality Disorder
This study aims to investigate the effects of methylphenidate on symptomatology in individuals with borderline personality disorder.
- Trial name
- NCT06759298
- Testing
- methylphenidate
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tanta University
Borderline Personality Disorder, Depressive Disorder
Systematic Use of Telepsychiatry for Outpatients
Implementation and evaluation of video consultation in psychiatric outpatient treatment. The study will focus on patients' experiences regarding the use of VC.
- Conditions
- Borderline Personality Disorder, Depressive Disorder, Ptsd, Anxiety Disorders
- Trial name
- NCT05516238
- Testing
- Case management
- Where
- Denmark
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Psychiatric Research Unit, Region Zealand, Denmark
Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Help-Seeking Behavior
Pilot the Use of VA Make the Connection Campaign to Facilitate Help Seeking Among Vulnerable Veterans
This pilot study seeks to determine if exposure to the Make the Connection campaign messages developed by the U.S. Department of Veterans Affairs (VA) is associated with changes in mental-health related outcomes, specifically…
- Trial name
- NCT03407443
- Testing
- Exposure to Make the Connection messages, Active Control Group
- Volunteers
- healthy volunteers welcome
- Sponsor
- Canandaigua VA Medical Center
Eating Disorders
Personality Pathology and Cerebral Processing in Eating Disorders
The proposed study will investigate whether, on the basis of personality traits and personality disorders as well as specific cerebral activation patterns shows differences in adolescent female with anorexia nervosa (AN), bulimia…
- Trial name
- EAT_FMRI (NCT02980120)
- Testing
- SCID-I, EAT, EDI-2
- Where
- Austria
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Borderline Personality Disorder
MRI Imaging in Borderline Personality Disorder
MRI Study for females ages 18-45 with Borderline Personality Disorder(BPD): This study is a non-treatment study that involves 2 visits. Study Hypothesis: 1.
- Trial name
- NCT00275288
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Minnesota