Clinical trials: Personality Disorders
Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Homeless Youth Study - Stepping Stone 2.0
Housing instability is both a cause and consequence of mental health problems. As such youth experiencing housing instability (e.g., homeless or marginally housed) have higher rates of mental health problems.Because of their…
- Trial name
- NCT03776422
- Testing
- Mobile self-help intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Mood Disorders
Gonadal Steroid Manipulation and Personality Characteristics: Association With Mood Fluctuations and in Vitro Fertilization (IVF) Outcomes
The current study's primary aim is to investigate the association between neuroendocrine fluctuations and mood disorders by monitoring mood states over distinct hormonal phases during in-vitro-fertilization (IVF) treatment.
- Trial name
- IVF (NCT01032421)
- Testing
- IVF procedure
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Obsessive Compulsive Disorder, Healthy
Cortical Excitability in Obsessive-Compulsive and Related Disorders
This study will use transcranial magnetic stimulation (TMS) to study the function of the cerebral cortex (outer layer of the brain) in people with obsessive compulsive disorder (OCD) and related disorders.
- Trial name
- NCT00029068
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Psychopathic Personality Trait
Can Psychopathy be Prevented? Clinical, Neuroimaging and Genetic Data
The goal of this clinical trial was to learn about the effect of maltreatment on psychological and brain characteristics in a group of children.
- Trial name
- NCT06028620
- Testing
- Trauma Focused-Cognitive Behavior Therapy
- Where
- Mexico
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Mexico
Borderline Personality Disorder, PTSD
Neural Correlates of Stress Hormones
To investigate which neuronal correlates underlie cortisol-induced enhancement of memory retrieval in PTSD and BPD.
- Trial name
- Cort-fMRI (NCT02523664)
- Testing
- Hydrocortisone
- Where
- Germany
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Dyssocial Behavior
Role of Oxytocin in Telling and Detecting Lies
The investigators are interested in the impact of intranasal oxytocin in unethical behavior.
- Trial name
- NCT02361177
- Testing
- Oxytocin
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Coronary Heart Disease (CHD)
Couples Coping With Coronary Heart Disease
The main purpose of this study is to examine the contribution of personality traits to marital satisfaction and well -being among couples coping with Coronary Heart Disease (CHD) and couples from the general population, and to…
- Trial name
- psychocardio (NCT01315834)
- Where
- Israel
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Posttraumatic Stress Disorder, Borderline Personality Disorder
STAIR for Trauma and Emotion Dysregulation
This study will examine the impact of Skills Training in Affective and Interpersonal Regulation (STAIR) group, using self-report measures, on Posttraumatic Stress Disorder (PTSD), emotional dysregulation, borderline personality…
- Conditions
- Posttraumatic Stress Disorder, Borderline Personality Disorder, Emotion Regulation
- Trial name
- NCT05397613
- Testing
- STAIR
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obsessive-Compulsive Disorder
ITreatOCD: Predicting the Efficacy of Internet-based Cognitive Behavioral Therapy in Obsessive-compulsive Disorder
In the current study, the investigators will characterize obsessive-compulsive disorder (OCD) patients and healthy controls with a comprehensive clinical and neuroimaging assessment, focusing on the basic psychological processes…
- Trial name
- iTREATOCD (NCT05906069)
- Testing
- ICBT
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Pedro Morgado
Prostatic Diseases
Character Traits and Stress in Suspected Prostate Cancer
It has previously been reported that men with prostate cancer are 1 ) reduced quality of life after diagnosis and treatment, 2 ) neuroticism increases the reduction in QoL related to treatment side effects, and 3) often have very…
- Trial name
- NCT02031029
- Where
- 2 sites in Norway
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Helse Stavanger HF
Mental Disorder
Mapping Personality Traits to Genes
Previous research involving families, twins, and adoption all support the idea that there is a substantial heritable aspect to personality.
- Trial name
- NCT00001414
- Where
- United States
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Psycho-social Support on Mental Health and Hope of Adolescents Affected by Earthquake in Nepal
Adolescents are prone to mental health problems such as post-traumatic stress disorder (PTSD) and depression which could become worse in the aftermath of disasters.
- Trial name
- NCT03387007
- Testing
- Psychosocial support training for school teachers
- Volunteers
- 1,912 people, healthy volunteers welcome
- Sponsor
- Tokyo University
Self-harm, Personality Disorder, Borderline
Self-harm Behaviour Among the Most At-risk Adolescents
In the proposed study, three objectives will be pursued: 1. To develop a method to identify more effectively the acute and long-term risk of adolescents with the most threatening self-harm behaviours. 2.
- Conditions
- Self-harm, Personality Disorder, Borderline, Epigenetic Disorder, Non-Suicidal Self Injury
- Trial name
- SH-MARA (NCT05765864)
- Testing
- Enrollment questionnaire, General questionnaire1, General questionnaire2, General questionnaire3, Columbia Suicide Severity Rating Scale (CSSRS), The Brief Non-Suicidal Self-Injury Assessment Tool (B-NSSI-AT)
- Where
- 2 sites in Slovenia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana, Faculty of Medicine
Emotional Dysfunction, Borderline Personality Disorder
Emotion Regulation Group Study
A clinical trial to evaluate the effects of an eight-week emotion regulation group intervention designed for adolescents (16-20 years old) on the levels of emotion dysregulation both self-reported by the adolescent and reported…
- Trial name
- EmoReg (NCT05734677)
- Testing
- Emotion regulation group
- Where
- Switzerland
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Camille Nemitz Piguet
Obsessive - Compulsive Disorder, Obsessive Compulsive Disorder (OCD)
Assessments of Obsessive-compulsive Symptoms in Patients With Substances Use Disorder
This observational, cross-sectional case-control study evaluates obsessive-compulsive symptoms among adults with substance use disorder compared with a demographically similar control group without substance use disorder.
- Conditions
- Obsessive - Compulsive Disorder, Obsessive Compulsive Disorder (OCD), Obsessive Compulsive Behavior, Substance Abuse Disorder
- Trial name
- NCT07395453
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Assiut University
Severe Mental Disorder, Schizophrenia
Development of a Model for Digital Monitoring of the Mental State of the Hospitalized Patient
This study presents the development and validation of a unique Digital Experience Sampling Method (ESM) questionnaire specifically adapted for monitoring changes in the mental state of patients during psychiatric hospitalization.
- Conditions
- Severe Mental Disorder, Schizophrenia, Personality Disorders, Mood Disorders
- Trial name
- NCT06182787
- Where
- Israel
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Obsessive - Compulsive Disorder
Neural Mechanisms of the Sensorymotor Circuit in Sensory Phenomena in OCD
The goal of this clinical study is to investigate the neural mechanisms of abnormal sensory phenomena in patients with Obsessive-Compulsive Disorder and to evaluate whether modulation of the insula-supplementary motor area…
- Trial name
- NCT07480408
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Borderline Personality Disorder
Stress & Social Cognition in Borderline Personality Disorder
The investigators will examine whether perceived social exclusion provoke a reduction in prosocial behavior in BPD patients.
- Trial name
- SOKO-1 (NCT04504994)
- Testing
- inclusion condition
- Where
- Germany
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Health Education, Health Promotion
Comparative Study of Empathy and Anxiety in the Different Academic Years, at the Beginning of Academic Year and Exam Period in Healthy Students.
Students from different health science degrees will carry out a study on the variables of empathy, anxiety and personality profile.
- Conditions
- Health Education, Health Promotion, Health Behavior
- Trial name
- NCT06514404
- Testing
- observational study
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Mayuben Private Clinic
Borderline Personality Disorder
Role Of Sensitivity to neuroEndocrine Systems in Social Decisions
The purpose of this research study is to investigate how personality traits and neuroendocrine systems relate to decision-making patterns in individuals 18-45 years old.
- Trial name
- ROSES (NCT06018727)
- Testing
- Hydrocortisone, Yohimbine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill