Clinical trials: Personality Disorders
Psychopathic Personality Trait, Conduct Disorder
The Efficacy of a Compassion Focused Therapy-based Intervention in Detained Youth
This non-randomized controlled trial with a control group aimed to assess the efficacy of a 20-session individualized Compassion Focused Therapy-based intervention, the PSYCHOPATHY.COMP, in reducing psychopathic traits (primary…
- Conditions
- Psychopathic Personality Trait, Conduct Disorder, Delinquency
- Trial name
- PSYCOMP (NCT03971682)
- Testing
- PSYCHOPATHY.COMP program., Treatment As Usual - TAU
- Where
- Portugal
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Schizotypal Personality Disorder
Compassion and Metacognition in Schizotypal Personality
The purpose of this study is to assess the safety and efficacy of a newly developed psychotherapy for schizotypal personality disorder.
- Trial name
- CMBT (NCT04764708)
- Testing
- Compassion and Metacognition Based Therapy, Cognitive Behavioral Therapy
- Where
- Italy
- Volunteers
- 16 people
- Sponsor
- Tages Onlus
Self-Harm, Deliberate, Borderline Personality Disorder
Dialectical Behavior Therapy vs Enhanced Usual Care for Suicidal and Self-harming Adolescents. 10 Year Follow-up
The purpose of the study is to evaluate the long-term efficacy of dialectical behavior therapy (DBT) in treatment of adolescents with deliberate self harm compared to enhanced usual care (EUC).
- Trial name
- NCT04298190
- Testing
- Dialectical Behaviour Therapy for Adolescents (DBT-A), Enhanced usual care
- Where
- Norway
- Volunteers
- 61 people
- Sponsor
- Oslo University Hospital
Emotional Instability Personality Disorder (Borderline Personality Disorder), Attention Deficit Hyperactivity Disorder
Emotional and Non-emotional Regulation in Patients With Emotional Instability and ADHD
The purpose of this study is to investigate how emotional and non-emotional regulation processes differ in EIP patients (with different levels of ADHD symptoms/ADHD-comorbidity) compared to controls.
- Conditions
- Emotional Instability Personality Disorder (Borderline Personality Disorder), Attention Deficit Hyperactivity Disorder, Healthy Controls
- Trial name
- NCT02797873
- Testing
- fMRI - Stroop task, fMRI - MID task, Stop Signal Task
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Prodromal Schizophrenia
Investigating the Role of Diazepam on Brain Function and Chemistry in Psychosis Risk
This study will investigate whether a single dose of diazepam (5mg) compared to placebo can modulate brain chemistry (GABA/glutamate levels) and function (blood flow, neural response and connectivity during tasks and at-rest) in…
- Trial name
- BENZOGAP (NCT06190483)
- Testing
- Diazepam 5 Mg Oral Tablet, Ascorbic Acid 50 Mg Oral Tablet
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- King's College London
Personality Disorders
Evaluating Adapted Structured Clinical Management for People With a Diagnosis of Personality Disorder
Camden and Islington NHS Foundation Trust in London has a Personality Disorder Service (PDS) which offers a number of evidence-based interventions to people with a diagnosis of Personality Disorder.
- Trial name
- NCT04207970
- Testing
- Adapted Structured Clinical Management
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- Camden and Islington NHS Trust
Prediabetes, Hyperglycemia
Personality Traits and Biochemical Risk Phenotypes
This prospective observational study investigates the association between personality traits and routine laboratory abnormalities in adults undergoing routine health assessment.
- Conditions
- Prediabetes, Hyperglycemia, Metabolic Syndrome
- Trial name
- PHEBiP (NCT07653048)
- Where
- Romania
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Medical Center TOPMED
Schizophrenia, Schizoaffective Disorder
Accelerated TMS in Psychosis
This study is to determine the tolerability and efficacy of an accelerated schedule of Transcranial Magnetic Stimulation for treating symptoms of psychotic disorders such as schizophrenia.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Prodromal Schizophrenia
- Trial name
- ATP (NCT05567848)
- Testing
- repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Beth Israel Deaconess Medical Center
Personality
Personality and Drug Use (PDU)
The study aims to assess whether the use of drugs relates to personality ratings. Specifically, we plan to investigate if people with different histories of substance use differentiate on personality assessments (current and…
- Trial name
- PDU (NCT05180149)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Quantified Citizen Technologies Inc.
Antisocial Personality Disorder
Positive Psychotheraphy and Antisocial Personality Disorder: Crime, Aggression, Anger
Studies on Antisocial Personality Disorder (ASPD), in which criminal behaviors, aggression and anger behaviors are frequently seen, are very rare.
- Trial name
- NCT04903938
- Testing
- Primary And Secondary Abilities Among The Individuals With Antisocial Personality Disorder Within The Scope Of Positive Psychotherapy: Their Relationship With Criminal Behaviors, Aggression And Anger
- Volunteers
- 3 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Borderline Personality Disorder
Five Factor Model Treatment for Borderline Personality Disorder
The primary purpose of this study is to explore acceptability, feasibility, and preliminary efficacy of a novel cognitive-behavioral treatment for borderline personality disorder (BPD).
- Trial name
- NCT04587518
- Testing
- Personality-Based Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shannon E. Sauer-Zavala
Alcohol Abuse, Drug Abuse
Adventure: Teacher Delivered Personality-targeted Interventions for Substance Misuse
Several personality factors have been shown to be associated with risk for alcohol and substance misuse, and differentiate substance abusers based on clinical profile, treatment response and susceptibility to other forms of…
- Conditions
- Alcohol Abuse, Drug Abuse, Depression, Panic Disorder
- Trial name
- Adventure (NCT00776685)
- Testing
- Personality-targeted interventions
- Where
- United Kingdom
- Volunteers
- 3,190 people, healthy volunteers welcome
- Sponsor
- King's College London
Glaucoma
Personality Characteristics and Compliance With Antiglaucoma Medication
Personality traits may influence to the drug compliance in glaucoma patients.
- Trial name
- GDC (NCT00481494)
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Yonsei University
Schizotypal Personality Disorder
Schizotypal Personality Disorder Risperidone
Neurophysiological indices of self-monitoring were assessed in a group of patients with Schizotypal Personality Disorder (SPD) and a control group. Both groups were assessed after the administration of risperidone and placebo.
- Trial name
- NCT02535156
- Testing
- Risperidone
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Borderline Personality Disorder
Personality Change Study for Borderline Personality Disorder
Participants with borderline personality disorder will undergo an a 2 - 4 week baseline assessment to determine level of outcomes of interest in the absence of treatment.
- Trial name
- NCT06005129
- Testing
- Personality-Based Therapy
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Shannon E. Sauer-Zavala
Pulmonary Function; Newborn, Abnormal, Infant Wheeze
Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function
Vitamin C supplementation (500 mg per day) given to pregnant women who can not quit smoking will improve the pulmonary function tests in their offspring measured at 3 months of age.
- Conditions
- Pulmonary Function; Newborn, Abnormal, Infant Wheeze, In-utero Nicotine, Second Hand Smoke
- Trial name
- VCSIP (NCT01723696)
- Testing
- Vitamin C +prenatal vitamin
- Where
- 2 sites in United States
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Anxiety Disorders
Anxiety Disorders in Children - Association With Neurodevelopmental Delay/Disorder
The main objective of the study is to examine the relationship between anxiety disorders and neurodevelopmental disorder/delay in children aged 7- 13 years.
- Trial name
- NCT00553085
- Where
- 2 sites in Norway
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Regionsenter for barn og unges psykiske helse
Acute Myocardial Infarction, Peripheral Artery Disease
Vastmanland Myocardial Infarction Study (VaMIS)
The main purposes of this study are: to describe the prevalence of peripheral artery disease (including lower extremity artery disease, carotid artery disease, renal artery disease, and abdominal aortic disease) in patients with…
- Conditions
- Acute Myocardial Infarction, Peripheral Artery Disease, Diabetes
- Trial name
- VaMIS (NCT01452178)
- Where
- Sweden
- Volunteers
- 1,008 people
- Sponsor
- Uppsala University
Addiction, Alcohol
Substance Consumption, Personality, and Cognitive Functioning of Chess Players
The aim of this project is to find out if there is a difference in addictive behavior, personality traits, and cognitive abilities between chess players and non-chess players.
- Conditions
- Addiction, Alcohol, Nicotine, Drugs
- Trial name
- NCT06346353
- Where
- Germany
- Volunteers
- 756 people, healthy volunteers welcome
- Sponsor
- Central Institute of Mental Health, Mannheim
Common Mental Disorders, Depression
Integrated Mental Health Care and Vocational Rehabilitation to People With to Common Mental Disorders
The purpose of this study is to investigate the efficacy of an integrated mental health care and vocational rehabilitation intervention for people on sick leave because of depression, stress, anxiety, personality- and functional…
- Conditions
- Common Mental Disorders, Depression, Anxiety, Personality Disorders
- Trial name
- IBBIS II (NCT04432129)
- Testing
- IBBIS II, Service as Usual
- Where
- Denmark
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Amager Hospital