Clinical trials: Personality Disorders
Borderline Personality Disorder
Transcutaneous Vagus Nerve Stimulation (tVNS) for Borderline Personality Disorder (tVNS-BPD)
The goal of this clinical trial is to test the efficacy of transcutaneous vagus nerve stimulation (tVNS) in borderline personality disorder.
- Trial name
- tVNS-BPD (NCT05892900)
- Testing
- Transcutaneous vagus nerve stimulation (tVNS)
- Where
- Sweden
- Volunteers
- 42 people
- Sponsor
- Sahlgrenska University Hospital
Deliberate Self Harm, Borderline Personality Disorder
Adapted Dialectical Behaviour Therapy for Adolescents With Deliberate Self-Harm: A Pre-post Observational Study
The investigators conducted a pre-post naturalistic study regarding changes observed associated with a 15-week course of an adapted form of dialectical behaviour therapy for adolescents.
- Trial name
- NCT02988037
- Testing
- A-DBT-A
- Volunteers
- 33 people
- Sponsor
- University of Ottawa
Severe Personality Disorder
The (Cost-)Effectiveness of Generalist Versus Specialist Treatment for Severe Personality Disorders'
The goal of this clinical trial is to investigate if generalist treatment (GIT-PD) is non-inferior in improving level op personality functioning compared to specialist treatment (MBT/ST) in patients with severe personality…
- Trial name
- P-DAET (NCT06789380)
- Testing
- Schema therapy, Mentalization-based treatment, Guideline-informed treatment for personality disorders
- Where
- 5 sites in Netherlands
- Volunteers
- 358 people
- Sponsor
- Arkin
Schizophrenia, Depression
Peer Support for Increasing Physical Activity in People With Serious Mental Illnesses
This study will determine the effectiveness of a peer support system in increasing physical activity and effecting health behavior change in people with serious mental illnesses.
- Conditions
- Schizophrenia, Depression, Bipolar Disorder, Anxiety Disorders
- Trial name
- NCT00458094
- Testing
- Physical activity intervention with peer support (PA+PS), Physical activity intervention without peer support (PA)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Psychiatric Disorders
A Dimensional Model for Personality Disorders in Later Life
Research on personality disorders (PDs) in older adults is currently limited. This is surprising, given that PDs are also common in this age group.
- Trial name
- NCT05548946
- Testing
- PID-5-BF+M and LPFS-BF 2.0 (self-report questionnaires), Secondary Questionnaires (self-report and informant questionnaires), Clinical Ratings of the dimensional model
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Anorexia, Personality
Anorexia and Personality Traits in Elderly Individuals
The aim of this study is to evaluate the relationship between age-related anorexia and personality traits in elderly individuals with comorbidities.
- Conditions
- Anorexia, Personality, Aging, Chronic Disease
- Trial name
- APETI (NCT05418270)
- Where
- Turkey (Türkiye)
- Volunteers
- 310 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Substance Abuse, Emergencies
Clinical Characteristics of Patients Referred to a Substance Abuse Liaison Department in an Academic Hospital, France
The Coalition on Psychiatric Emergencies (CPE) stressed in 2016 that emergency providers were increasingly recognizing the important role of the Emergency Department (ED) in reducing adverse outcomes associated with untreated…
- Conditions
- Substance Abuse, Emergencies, Personality Disorders, Substance Use Disorders
- Trial name
- AddictUrge (NCT04916028)
- Where
- France
- Volunteers
- 652 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Borderline Personality Disorder
Reflective Functioning and Psychotherapy Processes in MBT
Borderline personality disorder (BPD) is a pervasive mental disorder characterized by emotional instability, self-destructive behavior, identity problems and unstable relationships.
- Trial name
- NCT04157907
- Testing
- Mentalization based therapy
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Oslo University Hospital
Physical Activity, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Expanded Game Squad for Neurodiverse Youth
The proposed study will pilot the use of an adapted Game Squad intervention aimed at improving physical activity and other important health behaviors (nutrition, sleep hygiene, screen time habits) for children and adolescents…
- Conditions
- Physical Activity, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Health Behavior, Developmental Disorder
- Trial name
- NDGameSquad (NCT03665415)
- Testing
- NDGameSquad
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Merrimack College
Borderline Personality Disorder
Effects of Motive-Oriented Therapeutic Relationship in the Early-Phase Treatment of Borderline Personality Disorder
The present research aims at examining the effectiveness of a specific set of therapist relational interventions and attitudes, called the Motive-Oriented Therapeutic Relationship (MOTR), based on Plan Analysis (Caspar, 2007) in…
- Trial name
- MOTR (NCT01896024)
- Testing
- Psychiatric Management, Motive-oriented therapeutic relationship/Plan Analysis
- Where
- Switzerland
- Volunteers
- 85 people
- Sponsor
- University of Lausanne Hospitals
Borderline Personality Disorder
A Study on the Outcome and Its Influencing Factors in Patients With Borderline Personality Disorder
Borderline personality disorder (BPD) is a difficult chronic mental illness. This diagnosis is common in Western countries. Our researchers want to study the outcome and its influencing factors of BPD for the first time in China.
- Trial name
- NCT06005779
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Wuhan Mental Health Centre
Borderline Personality Disorder
TMS in Borderline Personality Disorder Patients
The purpose of this study is to determine the potential effects of repetitive transcranial magnetic stimulation in the improvement of neuropsychological deficits and symptomatology in borderline personality disorder patients.
- Trial name
- NCT02273674
- Testing
- Left rTMS 5 Hz, Right r TMS 1 Hz
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Instituto Nacional de Psiquiatría Dr. Ramón de la Fuente
Schizophrenia, Schizotypal Disorder
The OPUS YOUNG Trial. Early Intervention Versus Treatment as Usual for Adolescents With First-episode Psychosis
The OPUS YOUNG (OY) study investigates the efficacy of early intervention service versus treatment as usual (TAU) for adolescents aged 12-17 years with a first-episode psychosis.
- Conditions
- Schizophrenia, Schizotypal Disorder, Delusional Disorder, Acute and Transient Psychotic Disorder, Unspecified
- Trial name
- OPUS-YOUNG (NCT04916626)
- Testing
- OPUS YOUNG, Treatment as Usual
- Where
- Denmark
- Volunteers
- 284 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Personality Disorder, Borderline
Effectiveness Evaluation of 'The Endeavour Programme'
This study aims to evaluate the effectiveness of Dialectical Behaviour Therapy for adults with Borderline Personality Disorder attending Community Mental Health Services in Cork, Ireland.
- Trial name
- NCT03166579
- Testing
- Dialectical Behaviour Therapy
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Health Service Executive, Ireland
Borderline Personality Disorder
Preliminary Trial of the Effect of Glucocorticoid Receptor Antagonist on Borderline Personality Disorder (BPD)
Participants will be randomized to either Mifepristone 600mg once daily for seven days or Placebo tablet once daily for seven days. Rating scales, vital signs, cortisol levels will be collected for evaluation.
- Trial name
- NCT01212588
- Testing
- mifepristone
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Indiana University