Clinical trials: Personalized Nutrition
Homeostasis, Metabolism and Nutrition Disorder
Energy Metabolism Profiles Over Weight-loss and Eating Responses
This is an exploratory controlled before-after study, which involves 112 participants, of whom 28 are with normal weight and 84 are overweight or obese.
- Conditions
- Homeostasis, Metabolism and Nutrition Disorder, Healthy, Obesity
- Trial name
- NCT05785221
- Testing
- General lifestyle and nutritional education, Personalized nutritional and lifestyle weight reduction intervention
- Where
- China
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Sciences
Multiple Sclerosis
Personalized Nutrition Advice for Optimizing Dietary Calcium Intake in MS Patients
The main objective of this study is to measure effectiveness at 6 months of personalized dietary advice versus dietary counseling via delivery of a standard advice sheet for optimizing dietary calcium intake (assessed by a food…
- Trial name
- CalciCoach (NCT02664623)
- Testing
- Individual dietary consultations, Dietary advice sheet
- Where
- 2 sites in France
- Volunteers
- 182 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Postprandial Hyperglycemia, Metabolic Disorder, Glucose
Westlake N-of-1 Trials for Macronutrient Intake 2 ( WE-MACNUTR 2)
Diet and nutrition are key to maintain human health. Westlake N-of-1 Trials for Macronutrient Intake (WE-MACNUTR) trial investigates individualized postprandial glycemic responses to different proportions of dietary fat and…
- Trial name
- NCT05161182
- Testing
- High fat, low carbohydrate diet, Low fat, high carbohydrate diet
- Where
- China
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Westlake University
Obesity (Body Mass Index >30 kg/m2), Atelectasis, Postoperative
Dynamic Compliance-Guided Personalized PEEP During Laparoscopic Bariatric Surgery: Effects on Intraoperative Respiratory Parameters
Atelectasis may be encountered in the patient population aged 18-65 years undergoing elective laparoscopic bariatric surgery under general anesthesia with endotracheal intubation.
- Conditions
- Obesity (Body Mass Index >30 kg/m2), Atelectasis, Postoperative, PEEP With Dynamic Compliance, Individualized PEEP
- Trial name
- NCT07345650
- Testing
- Individualized approach
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Yeditepe University
MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, MASLD
Integrating Hepatological, Nutritional, and Psychological Support as a Multidisciplinary Management to Improve Long-term Clinical Outcomes in MASLD
Metabolic dysfunction associated Steatotic Liver Disease (MASLD) is frequently complicated by cardiometabolic (CMR) comorbidities, and prognosis is substantially influenced by acute cardiovascular events (ACE).
- Conditions
- MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, MASLD, Cardiovascular Events
- Trial name
- CoCoNut (NCT07366463)
- Testing
- Hepatologic-provided recommendations, Nutritional support, Psychological support
- Where
- Italy
- Volunteers
- 286 people
- Sponsor
- University of Campania Luigi Vanvitelli
Menopause, Postmenopausal Disorder
Metabotyping in the Postmenopausal Stage
Menopause is defined as the absence of menstrual periods for twelve consecutive months. Although the onset may vary, natural menopause occurs between the ages of 45 and 55 and is considered a stage in the aging process for women.
- Conditions
- Menopause, Postmenopausal Disorder, Postmenopausal Symptoms
- Trial name
- SHE-HEALTH (NCT05397015)
- Testing
- No intervention will be done
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fundació Eurecat
Diabetes, Heart Diseases
PREDICT 2: Personalized Responses to Dietary Composition Trial 2
Foods in the human diet can affect the development of diseases over time, such as diabetes or heart disease. This is because the amount and types of foods in the diet eat can affect a person's weight, and because different foods…
- Conditions
- Diabetes, Heart Diseases, Diet Habit, Diet Modification
- Trial name
- NCT03983733
- Testing
- Dietary Intervention
- Where
- United States
- Volunteers
- 1,139 people, healthy volunteers welcome
- Sponsor
- Zoe Global Limited
Diet, Healthy, Metabolic Disease
Interactions Between Diet, Microbiome and Abiotic Conditions in the Gut
The aim of this study is to explore the interplay between environmental (abiotic) factors in the gut and the gut microbiota composition, diversity and metabolism.
- Trial name
- PRIMA (NCT04804319)
- Testing
- 9-days habitual diet
- Where
- Denmark
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Hypertension, Dyslipidemia
A Novel Digital Tool Clinicians Can Use to Prescribe Exercise to Patients With Cardiovascular Disease Risk Factors
The investigators will conduct a feasibility and pilot efficacy randomized controlled trial to test the usability and user satisfaction of an evidence-based digital health tool the investigators developed for clinicians to use to…
- Conditions
- Hypertension, Dyslipidemia, Diabetes Mellitus, Obesity
- Trial name
- P3-EX (NCT07238556)
- Testing
- Experimental - 12 Week P3-EX Unsupervised Exercise Program with Virtual Weekly Oversight from Graduate Research Assistants, Active Control - 12 Week ACSM-PAVS Unsupervised Exercise Program with Virtual Weekly Oversight from Graduate Research Assistants
- Where
- 3 sites in United States
- Volunteers
- 72 people
- Sponsor
- University of Connecticut
Acute Stroke
Impact of Early, Personalized Nutritional Management on 1-month Mortality After Acute Stroke
This study evaluate the impact of early personalized nutritional management on 1-month mortality after acute stroke. In the randomised centres of the interventional group (early personalized nutritional management), each patient…
- Trial name
- AVC-NUT2 (NCT07065929)
- Testing
- Early nutritional management
- Where
- 12 sites in France
- Volunteers
- 3,084 people
- Sponsor
- University Hospital, Angers
Malnourished Elderly, Quality of Life (QOL)
Personalized Diet and Physical Exercise in Malnourished Older Adults
In this study, personalized diet therapy will be planned by expert dietitians for the volunteers, and they will be instructed on simple stretching and strengthening exercises they can perform independently at home.
- Conditions
- Malnourished Elderly, Quality of Life (QOL), BMI, Hand Grip Strength
- Trial name
- NCT06823739
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Istanbul University
Diabetes Mellitus, Type 2, Pre-diabetes
Models of Nutrition From Continuous Glucose Monitors
With this study, researchers want to conduct ambulatory studies in which people (healthy, with T2D, or at-risk of T2D) will consume a variety of pre-set and conventional meals in free-living conditions while wearing one or more…
- Conditions
- Diabetes Mellitus, Type 2, Pre-diabetes, Diet Habit, Diet, Healthy
- Trial name
- NCT04991142
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Non Dependant 60 to 75 Year-old Men and Women
Multidimensional Phenotyping Towards Personalized Preventive Nutritional Support for Elderly People
There is high inter-individual variability in the response to feeding, which is determined by multiple interacting factors such as age, sex, genotype, gut microbiota, eating behaviors, physical activity or even socio-demographic…
- Trial name
- MetabotypAGE (NCT06163794)
- Testing
- Nutritional postprandial test
- Where
- 3 sites in France
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Diabetes, Heart Diseases
Personalized Responses to Dietary Composition Trial 3
The PREDICT 3 study will build on previous research in over 2,000 individuals to further refine machine learning models that predict individual responses to foods, with the aim of advancing precision nutrition science and…
- Conditions
- Diabetes, Heart Diseases, Diet Habit, Diet Modification
- Trial name
- NCT04735835
- Testing
- Dietary Intervention
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 250,000 people, healthy volunteers welcome
- Sponsor
- Zoe Global Limited
Cancer, Sarcopenia
Personalized Cooking and Nutrition Guidance and Physical Activities Program to Reduce Muscle Loss in Advanced Cancer
People with advanced cancer often lose muscle over time. This can make them weaker, more tired, and reduce their quality of life. Many patients also struggle to eat because of changes in taste, smell, or appetite.
- Conditions
- Cancer, Sarcopenia, Muscle Mass Loss
- Trial name
- NCT07466862
- Testing
- Oncology Dietitian's Standard of Care, Personalized Culinary and Nutrition Therapy
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Gali Perel
Malnutrition, Child
The Effect of Continuous Egg Supplement on Personalized Nutri-omics in Primary School Children (SI-EGG STUDY)
This research compares the effects of one-year continuous whole egg supplement vs. egg yolk substitutes and control on anthropometry, biochemical blood parameters, metabolic enzymes and microbiome data in primary school children.
- Trial name
- NCT04896996
- Testing
- whole eggs, yolk-free egg substitutes
- Where
- Thailand
- Volunteers
- 635 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Overweight and Obesity
Effectiveness of a Precision Diet Based on Gene Expression Versus a Personalized Mediterranean-Style Diet in Weight Loss
The present randomized controlled trial aims to evaluate the relationship between gene expression profiling and the response to a precision diet compared to a personalized Mediterranean-style diet (control diet) in metabolically…
- Trial name
- NCT06435325
- Testing
- Precision diet, Control diet
- Where
- Spain
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Dietary Habits, Healthy Diet
Dietary Intervention Study on Food Based Dietary Guidelines for Sustainable and Healthy Lifestyles
The aim of the study is to provide proof of the effectiveness, acceptability, healthfulness and nutritional adequacy of dietary guidelines to reduce greenhouse gas emissions.
- Conditions
- Dietary Habits, Healthy Diet, Healthy Nutrition, Personalized Nutrition
- Trial name
- SuHeGuide (NCT05253547)
- Testing
- Healthy climate-friendly dietary guidelines, Healthy dietary guidelines
- Where
- 3 sites in Ireland, United Kingdom
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Non-Alcoholic Fatty Liver Disease, Obesity
Influence of the Diversity and Composition of the Microbiota in the Development of Pediatric Fatty Liver
The objectives of the present study are: 1) to identify the intestinal and salivary microbiota associated with the presence and severity of hepatic steatosis in children (Study I: case-control study), and 2) to develop a…
- Conditions
- Non-Alcoholic Fatty Liver Disease, Obesity, Metabolic Syndrome
- Trial name
- MicroKid (NCT04575506)
- Testing
- Multidisciplinary intervention program
- Where
- 2 sites in Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Pública de Navarra
Obesity & Overweight
Precision Lifestyle Intervention and Anthropometric, Nutritional, and Metabolic Health Outcomes
This clinical trial aims to recruit a core cohort of adults with normal weight, overweight, and obesity, but without other metabolic alterations, to undergo a six-month nutritional intervention.
- Trial name
- MAR-GEN (NCT07450066)
- Testing
- Diet
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of the Balearic Islands