Clinical trials: Persons With Psychiatric Disorders
Dementia, Neuro-Degenerative Disease
Lived Experience Narratives in Dementia
The Lived Experience Narratives in Dementia (LEND) research programme involves five work packages (WP). WP1 explores how people living with dementia use narratives and how narratives can impact them.
- Conditions
- Dementia, Neuro-Degenerative Disease, Alzheimer Disease, Caregiver Burden
- Trial name
- LEND (NCT07757178)
- Testing
- Online LEND Intervention
- Where
- 2 sites in United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Caregiver Burden, Lewy Body Disease
VOCALE LBD+ for Caregivers of Persons With Lewy Body Dementia
The goal of this clinical trial is to evaluate the feasibility, acceptability, and initial efficacy of the VOCALE LBD+ intervention in caregivers of persons living with Lewy Body Dementia.
- Conditions
- Caregiver Burden, Lewy Body Disease, Stress, Skill, Coping
- Trial name
- NCT05622734
- Testing
- VOCALE LBD+
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Washington
Dementia, Alzheimer Disease
The Healthy Patterns Sleep Study
The Healthy Patterns Study intervention is a home-based activity intervention designed to improve symptoms of circadian rhythm disorders (CRD) and quality of life (QOL) in home-dwelling persons with dementia.
- Conditions
- Dementia, Alzheimer Disease, Circadian Rhythm Disorders, Circadian Rhythm Sleep Disorder
- Trial name
- NCT03682185
- Testing
- Attention-Control Condition, Timed Activity Intervention
- Where
- United States
- Volunteers
- 421 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Depressive Disorder, Major
The Effect of Mediterranean Diet and Mindfulness Eating on Depression Severity in People With Obesity and Major Depressive Disorder
The present study investigates the effect of Mediterranean Diet and Mindful Eating on depression severity in people with obesity and major depressive disorder.
- Trial name
- MEDIMIND (NCT06621394)
- Testing
- nutritional intervention, Mindful Eating, Attention Control
- Where
- Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Sleep Disturbance, Stress
Yoga for Persons With Severe Visual Impairment
This study aims to provide novel information on the feasibility of yoga interventions for secondary symptoms related to severe vision loss, such as sleep disturbances, negative mood states, fall risk and balance.
- Conditions
- Sleep Disturbance, Stress, Anxiety, Depression
- Trial name
- RPY (NCT01366677)
- Testing
- Yoga Intervention
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Parkinson Disease
Feasibility of a Behavioural Activation Protocol to Support People With Parkinson's Enhanced by VR
The proposed research project will involve developing and testing the feasibility of a 6 week Behavioural Activation (BA) programme for people with Parkinson's Disease, which will be enhanced by Virtual Reality exercise…
- Trial name
- BAPP-VR (NCT07038603)
- Testing
- BAPP-VR
- Where
- United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Stroke, Internet-Delivered Cognitive Behavioural Therapy
ICBT for Persons With Stroke
Despite evidence for ICBT among those with other chronic conditions, its efficacy has yet to be evaluated among those with neurological conditions, including stroke.
- Conditions
- Stroke, Internet-Delivered Cognitive Behavioural Therapy, Depression, Anxiety
- Trial name
- NCT04667754
- Testing
- Internet-delivered Cognitive Behavioural Therapy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Nervous System Diseases
Effects of the COTID (Community Occupational Therapist in Dementia) Program and Usual Occupational Therapy Care on Recurrence of Falls at 12 Months in Elderly People With Neurocognitive Disorders Who Had Been Hospitalized for Falls, After Their Return Home
This project will enable optimization of specific carried out by occupationist for older adults discharged from hospital for falls: on the environmental dimension at the participant's home on the involvement of the caregiver…
- Trial name
- ErgoFalls (NCT06237218)
- Testing
- COTID program
- Where
- France
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Sleep, Sleep Deprivation
Sleep Loss and Energy Metabolism in People With Family History of Type 2 Diabetes.
The use of energy from food changes when people sleep. However, it is still not known if differences in the amount of nighttime sleep have an effect on the amount of energy that people who have a relative with type 2 diabetes…
- Conditions
- Sleep, Sleep Deprivation, Insulin Resistance, Type 2 Diabetes
- Trial name
- NCT00724087
- Testing
- 5.5-hour bedtime, 8.5-hour bedtime
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Obesity, Mental Illness
Weight Management & Wellness for People With Psychiatric Disabilities
The purpose of this study is to conduct a randomized controlled trial to test the effectiveness of an intervention called Nutrition and Exercise for Wellness and Recovery (NEW-R) in promoting healthy eating and increased physical…
- Trial name
- NCT05128045
- Testing
- NEW-R
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
PTSD, Sleep Disturbance
Electrical Vestibular Nerve Stimulation (VeNS) as a Method of Sleep Management in People With PTSD
This double blind randomized controlled study will enroll 20 subjects and will be conducted remotely. The study will be randomized for an 8-week period with a 1:1 active to sham device allocation.
- Conditions
- PTSD, Sleep Disturbance, Insomnia
- Trial name
- NCT04780893
- Testing
- Modius Sleep
- Volunteers
- healthy volunteers welcome
- Sponsor
- Neurovalens Ltd.
Caregiver Burden, Stress
Evaluation of Mobile Apps for Informal Caregivers of People Living With Dementia
The purpose of this study is to evaluate the effectiveness of two currently available apps for unpaid caregivers of people living with dementia.
- Conditions
- Caregiver Burden, Stress, Dementia
- Trial name
- NCT05217004
- Testing
- Dementia Talk mobile application, CLEAR Dementia Care mobile application
- Where
- Canada
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- University of Regina
Mental Health Disorder, Substance Use Disorder
The IMPROV Project: Improving Mental Health and Substance Use Treatment Provision (IMPROV) Among People Living With HIV (Human Immunodeficiency Virus) in Atlanta
This project consists of a pilot trial to assess the preliminary impact of a stigma-reduction training to reduce clinic-level stigma and the You℞ Decision prescribing platform to increase HIV care providers' self-efficacy related…
- Conditions
- Mental Health Disorder, Substance Use Disorder, Stigmatization, Implementation Science
- Trial name
- IMPROV (NCT05415891)
- Testing
- Modified Health Policy Project (HPP) HIV-Stigma and Discrimination Reduction Training Curriculum, You℞ Decision prescribing platform
- Where
- 2 sites in United States
- Volunteers
- 333 people, healthy volunteers welcome
- Sponsor
- RTI International
Anxiety, Depression
Feasibility Study on the Use of Mindfulness-based Intervention for Family Carers of People With Dementia
The aim of this study is to examine which mindfulness-based intervention protocol, MBCT or MBSR, is more suited for use among local carers of people with dementia (PWD), as measured by better mental health outcomes in PWD such as…
- Conditions
- Anxiety, Depression, Dependency Burden, Stress, Psychological
- Trial name
- NCT02667782
- Testing
- Mindfulness-Based Stress Reduction (MBSR), Mindfulness-Based Cognitive Therapy (MBCT)
- Where
- 2 sites in Hong Kong
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Autistic Spectrum Disorders
A Pilot Trial of a Developmental, Individual-Difference, Relationship-Bases (DIR)/Floortime for Children With Autistic Spectrum Disorders
Thirty two children age 2-6 years are recruited into the study and the randomization will be stratified for chronological age and symptom severity into 2 main groups, intervention and control.
- Trial name
- DIR (NCT00954083)
- Testing
- DIR/Floortime, Routine care
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Social Anxiety Disorder
Effect of Nursing Interventions Using Roy Adaptation Model with Virtual Reality on Social Anxiety in Youth
The study was conducted to determine the effect of nursing practices based on the RAM integrated with VR on the social anxiety level of young people.The main questions it aims to answer are: H1: "Nursing practices based on the…
- Trial name
- NCT06586944
- Testing
- Nursing Practices Based On Roy Adaptation Model Integrated With Virtual Reality, Roy Adaptation Model
- Where
- Turkey (Türkiye)
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Aytuğ Türk
Autism Spectrum Disorder
Improving Daily Living Skills in People With Autism Spectrum Disorder Through a Personalised Serious Game
This study evaluates the efficacy of a rehabilitation intervention for people with Autism Spectrum Disorder through an individualised serious game developed for improving skills related to a specific daily living activity…
- Trial name
- NCT04295746
- Testing
- Serious Game ShopAut
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Federico II University
Autism Spectrum Disorders
A Study of a Developmental,Individual-Difference,Relationship-Bases/Floortime Intervention for Children With Autistic
Thirty eight autistic spectrum disorder children age 2-6 years recruited into the study. The new treatment intervention is based on the DIR Model. Parents will be coached at the start and then every 3-4 months for 1 year.
- Trial name
- DIR (NCT00954213)
- Testing
- DIR/Floortime parent intervention
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Cognition Disorders in Old Age
Study on the Effectiveness and Safety of Two Olive Extract- Based (Olea Europea L. Folium) Supplements, Alone or Combined With a Mullein Extract (Verbascum Thapsus L. Herba Cum Floribus), for the Maintenance of Cognitive Function.
The goal of this clinical trial is to learn if two food supplements based on olive leaf extract, alone or combined with mullein extract, help maintain cognitive function in older adults with mild cognitive impairment (MCI).
- Trial name
- NCT07586410
- Testing
- ACTIVE TREATMENT 1 - OLI-COGNITIVE FOOD SUPPLEMENT, ACTIVE TREATMENT 2 - OLI-VERB-COGNITIVE FOOD SUPPLEMENT
- Where
- Italy
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- ISTITUTO FARMOCHIMICO FITOTERAPICO: EPO SRL
Parkinson Disease, Parkinsonism
Misfolded Proteins in the Skin of People With Parkinson's Disease and Other Parkinsonism
The purpose of this study is to determine whether identification of misfolded proteins in the skin will help to determine what sort of parkinsonism someone has.
- Conditions
- Parkinson Disease, Parkinsonism, Dementia With Lewy Bodies, Multiple System Atrophy
- Trial name
- NCT04518059
- Testing
- punch skin biopsy
- Where
- 2 sites in United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center