Clinical trials: Persons With Psychiatric Disorders, open to volunteers
Serious Mental Illness, Older Adults
A Pilot Randomized Controlled Trial of the Hopeful and Healthy Living Program
The goal of this clinical trial is to learn if a novel psychosocial intervention is effective in helping adults over 50 with serious mental illness (SMI) increase their social connections and participate in more healthy lifestyle…
- Trial name
- (HHL) (NCT06940843)
- Testing
- Hopeful and Healthy Living (HHL)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Boston University Charles River Campus
Schizophrenia
The Effect of an Individual Empowerment Program Provided to Relatives of Schizophrenia Patients
Psychoeducation provided to family members caring for individuals with schizophrenia. Has been found to positively impact caregivers' psychological well-being and the effective management of schizophrenia patients.However…
- Trial name
- NCT07173192
- Testing
- Individual empowerment program
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Istanbul Arel University
Multiple Sclerosis, Gait Disorders, Neurologic
Investigating the Effects of Wearable Robotic Exoskeleton for Improving Mobility and Cognition in Persons With MS
The purpose of this research study is to evaluate the usefulness of a wearable robotic exoskeleton device (Ekso-GT), to improve learning and memory, and gait therapy in persons with walking disability due to Multiple Sclerosis.
- Conditions
- Multiple Sclerosis, Gait Disorders, Neurologic, Motility Disorder, Cognitive Impairment
- Trial name
- NCT04855825
- Testing
- Robotic Exoskeleton Rehabilitation, Conventional Gait Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Kessler Foundation
Alcohol Use Disorder, Cognition Disorders
Influence of Individual Traits on Adaptation Processes in Individuals With Alcohol Use Disorder
Alcohol Use Disorder (AUD) is a chronic condition that affects behavior, decision-making, and the ability to adapt to changing situations.
- Trial name
- TIPA (NCT07468825)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Knee Osteoarthritis
Effect of an Information- and Self-management App for People With Knee Osteoarthritis
The primary aim of the trial is to assess if an information- and self-management app provided in the period between referral and consultation in specialist healthcare can improve knowledge about osteoarthritis and decision…
- Trial name
- OA-AID (NCT07603973)
- Testing
- Information- and self-management app, Control
- Where
- Norway
- Volunteers
- 204 people
- Sponsor
- Diakonhjemmet Hospital
Multimorbidity, Older Adults (65 Years and Older)
Integrated Care for Older Adults With Major Depression and Physical Multimorbidity - The I-CONNECT
The goal of this clinical trial is to learn if I-CONNECT (Integrated Care for Older Adults with Major Depression and Physical Multimorbidity) can improve the health and well-being of older adults with depression or bipolar…
- Conditions
- Multimorbidity, Older Adults (65 Years and Older), Mood Disorders, Depression - Major Depressive Disorder
- Trial name
- I-CONNECT (NCT07211750)
- Testing
- integrated care intervention tailored to the needs of older adults leaving at home with mood disorders and multimorbidity in Leuven
- Where
- Belgium
- Volunteers
- 82 people
- Sponsor
- KU Leuven
Quality of Life
A Hybrid Effectiveness-Implementation and Cost-Utility Evaluation of a Support Programme for Informal Carers of People With Dementia in Primary Care (EsCuidar2)
The aim of this study is to evaluate whether the School of Caring programme improves quality of life and reduces caregiver burden among informal carers of people living with dementia.
- Trial name
- EsCuidar2 (NCT07861789)
- Testing
- School of Caring Programme
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Bipolar Disorder I or II
A Compassionate-focused Intervention for Older People with Bipolar Disorder
The aim of this study is to determine whether it is feasible to deliver a 9-session compassionate-focused therapy for older people with bipolar disorder.
- Trial name
- NCT06882590
- Testing
- Compassionate-focused therapy
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- University of Manchester
Intellectual Disabilities (F70-F79), Autism Spectrum Disorder
Emotion Processing and Regulation in People With Intellectual Disability
BACKGROUND Intellectual disability (ID) is neurodevelopmental disorder with social impairments, in areas such as interpersonal communication skills and emotion regulation.
- Trial name
- EPRID (NCT06894264)
- Testing
- Emotion regulation
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Falls, Intellectual Disabilities (F70-F79)
Falls In Spanish People With Intellectual Disabilities: Risk Factors And Predictive Equation. Falls.Di Study
This multicenter study aims to understand the specific risk factors for falls in Spanish people with intellectual disabilities in order to design an instrument to assess the risk of future falls in this population.
- Conditions
- Falls, Intellectual Disabilities (F70-F79), Risk Factors
- Trial name
- Falls_Di (NCT07282704)
- Where
- Spain
- Volunteers
- 600 people
- Sponsor
- Fundación Hospitalarias Betanzos
Well-Being, Psychological, Mood Disturbance
Neurofeedback and Well-Being Among People With Co-Occurring Obsessive Compulsive Disorder and Post-traumatic Stress Symptoms
The proposed study will collect novel data evaluating the feasibility of a neurofeedback training program delivered to prospective clients with a history of clinically concerning trauma-related mental health symptoms who are on a…
- Conditions
- Well-Being, Psychological, Mood Disturbance, Emotional Regulation, Dissociation
- Trial name
- NCT07217925
- Testing
- Neuroptimal (Zengar, Inc.) Neurofeedback
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Wayne State University
Cancer, Psycho-Oncology
What Impact Does an Initial Psycho-oncological Contact Have on People With Cancer?
When diagnosed with cancer, patients or their relatives may, if they wish, on the recommendation of the treatment team and/or in cases of high stress, seek psycho-oncological support.
- Trial name
- PICS (NCT07544446)
- Testing
- initial psycho-oncological contact, Standard
- Where
- 5 sites in Switzerland
- Volunteers
- 148 people
- Sponsor
- Lindenhofgruppe AG
HIV-1-infection, Opioid Use Disorder
Evaluation of Switch to Dolutegravir/Lamivudine (DTG/3TC) From Current Suppressive Antiretroviral Therapy in People Living With HIV (PLWH) Receiving Opioid Agonist Therapy (OAT)
The goal of this clinical trial is to determine the efficacy of Dolutegravir/Lamivudine (DTG/3TC), or "Dovato", in virally-suppressed (HIV-1 RNA < 200 copies/mL) individuals receiving opioid agonist therapy such as methadone…
- Trial name
- NCT06580873
- Testing
- DOVATO
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Saskatchewan Health Authority - Regina Area
Alcohol Use Disorder, Insomnia
Daridorexant for People With Insomnia and Alcohol Use Disorder Study
The goal of this clinical trial is to see if a sleep medication, daridorexant (DTX), can help decrease drinking in people who have alcohol use disorder (AUD) and insomnia.
- Trial name
- DIAS (NCT07701928)
- Testing
- Daridorexant, Brief Counseling, MEMS and Medication Accounting
- Where
- United States
- Volunteers
- 205 people
- Sponsor
- Sterling McPherson
Parkinson's Disease (PD), Alzheimer's Disease (AD) and Related Disorders
Moving Yourself in Space and Time: MYSTIC
This study is being done to answer the question: Do people with Parkinson's benefit from a new stepping therapy, and how do people with Parkinson's best learn new steps and rhythms set to music? Researchers will also compare…
- Conditions
- Parkinson's Disease (PD), Alzheimer's Disease (AD) and Related Disorders, Older Adults (60 - 85 Years Old)
- Trial name
- MYSTIC (NCT07697664)
- Testing
- Complex Rhythmic Movement Sequences (CRMS) Sessions
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Emory University
Mild Cognitive Impairment
The Impact of Physical Exercise on Working Memory in Elderly People With Mild Cognitive Impairment
Age-related cognitive decline has evolved into a global public health concern, with deteriorated executive function serving as its predominant manifestation.
- Trial name
- NCT07644156
- Testing
- Resistance band exercise intervention, Brisk walking intervention, Eight-Section brocade exercise intervention
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Shanghai University of Sport
Mild Cognitive Impairment (MCI)
Non-pharmacological Interventions for People With Mild Cognitive Impairment in the Community
Mild cognitive impairment (MCI) may increase the risk of dementia. This study will evaluate an 8-week community-family mutual support intervention for adults aged 60 years or older with MCI.
- Trial name
- CNPI-MCI (NCT07703267)
- Testing
- Community-Family Mutual Support Intervention, Routine Community Care
- Volunteers
- 70 people
- Sponsor
- Anhui Medical University
Subjective Cognitive Decline, Alzheimer Disease
Using Artificial Intelligence to Detect Early Signs of Alzheimer's Disease in People With Memory Concerns
AHEAD is a prospective, longitudinal, risk-stratified single-arm interventional study enrolling 300 patients with Subjective Cognitive Decline (SCD) at IRCCS San Raffaele Hospital, Milan, Italy.
- Conditions
- Subjective Cognitive Decline, Alzheimer Disease, Mild Cognitive Impairment, Cognitive Decline
- Trial name
- AHEAD (NCT07652931)
- Testing
- High-frequency Transcranial Magnetic Stimulation (TMS), Digital Cognitive Training, Structured Physical Exercise
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- IRCCS San Raffaele
Attention-Deficit/Hyperactivity Disorder (ADHD), Autism Spectrum Disorder
Home Play-based Intervention for Parents and Infants
The goal of this clinical trial is to learn whether a 12-week home-based intervention (Sociometric Play-based Remediation of Individual Neurodevelopmental Trajectories (SPRINT)) helps support parenting and the development of…
- Conditions
- Attention-Deficit/Hyperactivity Disorder (ADHD), Autism Spectrum Disorder, Premature Birth, Global Developmental Delay
- Trial name
- SPRINT (NCT07716072)
- Testing
- SPRINT Intervention, Waitlist Protocol
- Where
- Singapore
- Volunteers
- 120 people
- Sponsor
- Nanyang Technological University
Diabetes, Alzheimer's Disease (Incl Subtypes)
Enhancing Shared Decision-making to Guide Care for People With Dementia and Diabetes
The goal of this study is to test CGM ASSIST. This is a digital tool that uses an interactive information display-an easy-to-read screen designed to help people with dementia (or memory loss) and diabetes, as well as their…
- Conditions
- Diabetes, Alzheimer's Disease (Incl Subtypes), Dementia, Hypoglycemia
- Trial name
- CGM ASSIST (NCT05643144)
- Testing
- Continuous Glucose Monitoring
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Indiana University