Clinical trials: Persons With Psychiatric Disorders
Alzheimer Disease, Dementia
Care Coordination System for People With Dementia
Dementia, a chronic disease of aging, is characterized by progressive cognitive decline that interferes with independent functioning.
- Conditions
- Alzheimer Disease, Dementia, Dementia Alzheimers
- Trial name
- NCT04308512
- Testing
- Active Nili device, Passive Nili system
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Bijan Najafi, PhD
Bipolar Disorder (BD), Quality of Life (QOL)
Evaluating the PolarUs App in People With Bipolar Disorder
Our team recently pilot tested a new mobile app, PolarUs, co-designed with people who live with bipolar disorder (BD), to support BD self-management and quality of life (QoL) measurement.
- Trial name
- NCT07890805
- Testing
- PolarUs Mobile App
- Where
- Canada
- Volunteers
- 504 people
- Sponsor
- University of British Columbia
Dementia of Alzheimer Type, Alzheimer Disease
Telehealth-enabled Integrated Palliative Care for People With Dementia
In prior work, this team developed a telehealth primary care model (TIPC), designed in close partnership with patients and clinicians to address a widespread increase in telehealth use during the COVID-19 pandemic.
- Conditions
- Dementia of Alzheimer Type, Alzheimer Disease, Frontotemporal Degeneration, Lewy Body Dementia
- Trial name
- IBC (NCT05524181)
- Testing
- Telehealth Integrated Primary Care (TIPC)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Thomas Jefferson University
Severe Mental Disorder, Obesity
Health Education Programme Through Physical Exercise for People With Severe Mental Disorders
The goal of this clinical trial is to [learn about, test, compare etc.] in individuals with severe mental disorders and obesity comorbid.
- Trial name
- HEPPE-PSMI (NCT06069739)
- Testing
- Guided physical activity, Standard physical activity
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Mild-moderate Cognitive Impairment
Train Your Brain Fitness SC: An Exercise Intervention for People With Cognitive Impairments
The goal of this clinical trial is to test a twice a week, moderate intensity exercise and coaching program (an in-person group and a distance group) for adults with mild-moderate cognitive impairments living in South Carolina.
- Trial name
- NCT06799429
- Testing
- Supervised Exercise and Behavior Modification Support, Monitored Exercise and Behavioral Modification Support
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of South Carolina
Cognitive Impairment, Older People--Abuse of
Pre- and Post TAVI Cognitive Functioning and Intraoperative Carotid Flow Measurements
Purpose: 1. Measuring and optimize the usability of the BAMCOG (games to measure cognitive functioning) 2. Concurrent validation of BAMCOG with MoCA to see if BAMCOG can serve as a monitoring instrument/screener 3.
- Conditions
- Cognitive Impairment, Older People--Abuse of, Aortic Stenosis, Severe
- Trial name
- NCT05813353
- Where
- Netherlands
- Volunteers
- 54 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Schizophrenia and Disorders With Psychotic Feature, Psychotic Episode
Mindfulness-based Social Cognition Training for Psychosis (SocialMind): A Feasibility Study
The current investigation has been designed to test the feasibility of a mindfulness-based social cognition training (SocialMind) for people with a first episode of psychosis (AGES-Mind Study, NCT03309475).
- Trial name
- NCT03434405
- Testing
- SocialMind, Psychosocial treatment, Psychotropic treatment
- Where
- Spain
- Volunteers
- 27 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Intellectual Disabilities With Other Behavioral Symptoms, Acceptance Processes
Evaluation of an ACT and PBS Group for Parents and Education Staff
Parents and education staff who work with children with intellectual disabilities (ID) are known to be at a higher risk of experiencing psychological distress.
- Conditions
- Intellectual Disabilities With Other Behavioral Symptoms, Acceptance Processes, Psychological Distress, Burnout, Professional
- Trial name
- NCT03917329
- Testing
- ACT and PBS group workshop
- Where
- 2 sites in United Kingdom
- Volunteers
- 37 people
- Sponsor
- University of Edinburgh
Major Depressive Disorder (MDD)
The WORKER Study: Escitalopram and Telephone-based Cognitive Behaviour Therapy (CBT) for Depressed Working People
This study will investigate the additional benefits of telephone-based cognitive behavioral therapy (Tel-CBT) as added treatment to an antidepressant (escitalopram) in working people with major depressive disorder (MDD) versus…
- Trial name
- NCT00702598
- Testing
- Telephone-based Cognitive Behaviour Therapy (CBT), Telephone reminder calls
- Where
- Canada
- Volunteers
- 105 people
- Sponsor
- University of British Columbia
Insomnia, Sleep Efficiency
Feasibility of Non-pharmacological Insomnia Therapy in People Living With HIV
To establish with a prospective randomized placebo-controlled study the feasibility of allied-health personnel-administered cognitive behavioral insomnia therapy (CBTI) as a means of improving HIV/AIDS treatment adherence.
- Trial name
- NCT01804907
- Testing
- Cognitive Behavioral Therapy, Behavioral Modification
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Duke University
Schizophrenia, Metabolic Disturbance
Accelerated cTBS on Metabolic Dysfunction in People With Schizophrenia
cTBS is a promising novel intervention, which has strong potential on moderating disease syndrome. However, the most effective pattern of the cTBS is still under debate.
- Conditions
- Schizophrenia, Metabolic Disturbance, Eating Behavior, Transcranial Magnetic Stimulation
- Trial name
- NCT05358899
- Testing
- accelerated theta burst stimulation
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Central South University
Mild Cognitive Impairment, Mild Dementia
Computer-based Cognitive Rehabilitation Program for Healthy Older Adults, Older People With Mild Cognitive Impairment and Mild Dementia
This study will adopt a newly developed computer-based cognitive rehabilitation program targeting the encoding stage of memory. The aims of the study are: 1.
- Conditions
- Mild Cognitive Impairment, Mild Dementia, Healthy Older Adults
- Trial name
- NCT03430401
- Testing
- Perceptual-based memory encoding, Semantic-based memory encoding, Cognitive stimulation
- Where
- Australia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Western Sydney
Schizophrenia, Schizoaffective Disorder
Galantamine for Cognition in People With Schizophrenia
This study is a double-blind, placebo-controlled trial of the nicotinic receptor agonist, galantamine, for the improvement of memory and attention in people with schizophrenia and schizoaffective disorder.
- Trial name
- NCT00320736
- Testing
- galantamine
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- North Suffolk Mental Health Association
Insomnia, HIV
RCT of CBT for Insomnia With PLWHA
The proposed study will consist of a randomized controlled trial (RCT) comparing a known efficacious treatment for insomnia (CBT-I) to a sleep hygiene (SH) comparison condition.
- Conditions
- Insomnia, HIV, Aids
- Trial name
- NCT02259101
- Testing
- CBT-I Treatment Condition, SH Comparison Condition
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Emory University
Salutogenesis, Mental Health Disorder
Salutogenic Approach Based Interview With People With Schizophrenia
This study determines the effectiveness of the interviewing based on salutogenic approach on the sense of coherence and resilience of people with schizophrenia.
- Conditions
- Salutogenesis, Mental Health Disorder, Schizophrenia, Sense of Coherence
- Trial name
- NCT04740944
- Testing
- Salutogenic Approach Based Interview
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people
- Sponsor
- Istanbul University - Cerrahpasa
Psychomotor Status, Schizophrenia
The Motor Neurological Soft Signs (MNSS) in Persons With Schizophrenia
The aim is to contribute to the knowledge of the relationship between Motor Neurological Soft Signs (MNSS) and schizophrenia, as well as to point out the implications and recommendations for clinical and rehabilitative practices…
- Conditions
- Psychomotor Status, Schizophrenia, Motor Skills Disorders
- Trial name
- MNSS (NCT04495998)
- Testing
- Brief Motor Scale_portuguese version (BMS_pt)
- Where
- Portugal
- Volunteers
- 103 people
- Sponsor
- Faculdade de Motricidade Humana
Alzheimer Disease, Dementia
Effects of Exercise on Functional Ability in People With Dementia in Nursing Homes:a Cluster Randomised Controlled Trial
This is a cluster randomised controlled trial composed of two research arms: exercise training group (experimental group) and a social activity group (control group).
- Trial name
- LEDEN (NCT02444078)
- Testing
- Exercise, Social Activity
- Where
- 8 sites in France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Toulouse
HIV, Mental Health
NOLA GEM: Feasibility and Acceptability of an MHealth Intervention for Violence-affected PLWH
The objective of the proposed research is to conduct formative work to develop, pilot and refine a smartphone delivered intervention for violence affected people living with HIV utilizing a novel spatial-temporal methodology…
- Conditions
- HIV, Mental Health, Substance Use
- Trial name
- NCT05784714
- Testing
- NOLA GEM
- Where
- 4 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Tulane University
Dementia Mild, Mild Cognitive Impairment
An Advance Care Planning Programme for Persons With Early Stage Dementia in the Community
Advance care planning (ACP) has been widely advocated for persons with early stage dementia (PWEDs) and persons with mild cognitive impairment (MCI).
- Trial name
- NCT04491578
- Testing
- ACP programme "Have a Say"
- Where
- 10 sites in Hong Kong
- Volunteers
- 100 people
- Sponsor
- Hong Kong Metropolitan University
Alcohol Dependence, Insomnia
Pharmacotherapy and Mechanisms of Sleep Disturbance in Alcohol Dependence
Insomnia and other sleep abnormalities are common, persistent, and associated with relapse in alcohol-dependent patients. The overall, long-term objectives of the proposed research are to investigate the neurophysiologic…
- Trial name
- MA (NCT01014533)
- Testing
- Gabapentin dispensed to subject.
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Dr. Kirk Brower
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