Clinical trials: Persons With Psychiatric Disorders
Alzheimer's Disease
A First in Human Study of IBC-Ab002 in Persons With Early Alzheimer's Disease (AD)
This is a randomized, double-blind, placebo-controlled first-in-human, Phase 1, safety, tolerability, pharmacokinetic (PK) and preliminary exploratory activity study of escalating multiple intravenous (IV) doses of IBC-Ab002 in…
- Trial name
- NCT05551741
- Testing
- IBC-Ab002
- Where
- 10 sites in Israel, Netherlands and 1 more
- Volunteers
- 40 people
- Sponsor
- Immunobrain Checkpoint
Schizophrenia Spectrum and Other Psychotic Disorders
Cognitive Behavior Therapy for Patients With Psychoses.
Patients with psychoses are randomized either to group treatment (ACT) or individual CBT for 18 sessions.
- Trial name
- NCT03501888
- Testing
- Cognitive Behavior Therapy, Acceptance and Commitment Therapy
- Volunteers
- 16 people
- Sponsor
- Karolinska Institutet
Dementia, Caregiver Mental Health
Forest Bathing Intervention for Persons Living with Dementia and Family Carers
This study assessed the feasibility and acceptability of a forest bathing intervention for people living with dementia and their family carers, and examined its effectivness on care burden and quality of life by comparing to an…
- Trial name
- NCT06813196
- Testing
- Forest Bathing, Art activity
- Where
- Hong Kong
- Volunteers
- 107 people
- Sponsor
- The University of Hong Kong
Schizophrenia, Schizoaffective Disorder
Remediation of Visual Perceptual Impairments in People With Schizophrenia
The purpose of this study is to evaluate the effectiveness of a visual remediation intervention for people with schizophrenia. The intervention targets two visual functions that much research has shown are impaired in many people…
- Trial name
- VRiS (NCT03314129)
- Testing
- UltimEyes, Contour Integration Training, UltimEyes + Contour Integration Training
- Where
- 2 sites in United States
- Volunteers
- 79 people
- Sponsor
- University of Rochester
ADHD, Autism Spectrum Disorders
Internet-based Support for Young People With ADHD and Autism - a Controlled Study
Young people between age 15 and 25 with ADHD and/or autism spectrum disorders are offered internet-based support and coaching during eight weeks (chat and e-mail).
- Trial name
- NCT02300597
- Testing
- Internet based support and coaching
- Where
- Sweden
- Volunteers
- 45 people
- Sponsor
- Göteborg University
Major Depressive Disorder, Bipolar Disorder
Testing the Value of Smartphone Assessments of People With Mood Disorders
The purpose of this study is two-fold: 1. To identify the best smartphone data features (based on keyboard, sensor, voice/speech data) that correlate with mood, anxiety, and cognitive assessments in patients with Major Depressive…
- Trial name
- NCT03429361
- Testing
- Health by Mindstrong
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Mindstrong
Autism Spectrum Disorder, Intellectual Disabilities
An Evaluation of Care (Education) and Treatment Reviews for People With Learning Disabilities and Autistic People
Aims In this research project, we will determine whether Care (Education) and Treatment Reviews are helpful for people with learning disabilities and autistic people and their families.
- Trial name
- CECiLiA (NCT06918483)
- Volunteers
- 695 people
- Sponsor
- Coventry and Warwickshire Partnership NHS Trust
Depression
Collabri Flex - Effect of Collaborative Care for People With Depression in General Practice
The aim of the study Collabri Flex is to: Develop a Danish model for collaborative care for patients with depression in general practice, based on past experience gained in the Collabri Project.
- Trial name
- Collabri Flex (NCT03113201)
- Testing
- Collaborative care, Consultations-Liaison
- Where
- Denmark
- Volunteers
- 389 people
- Sponsor
- Amager Hospital
Alcohol Drinking, Chronic Inflammation
30-to-90 Day Challenge: Effects of Alcohol Cessation on Health Outcomes
The objective for this project is to determine whether how certain behavioral and health functions change in persons with heavy drinking when they stop (or reduce) drinking for 30 days, and whether changes continue for up to 90…
- Conditions
- Alcohol Drinking, Chronic Inflammation, Neurocognitive Dysfunction, Liver Diseases
- Trial name
- NCT03353701
- Testing
- Contingency Management (CM)
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Florida
Adjustment Impairment, Accident
SelFIT: Internet-based Treatment for Adjustment Problems After an Accident
In this study, people who suffer from adjustment problems after having experienced an accident will be randomized to one of two study groups.
- Conditions
- Adjustment Impairment, Accident, Adjustment Disorders, Mental Disorder
- Trial name
- SelFIT (NCT03785912)
- Testing
- Internet-based self-help
- Where
- Switzerland
- Volunteers
- 23 people
- Sponsor
- University of Bern
Hypertension, Depression
Patient-Centred Innovations for Persons With Multimorbidity - Quebec
The aim of Patient-Centred Innovations for Persons With Multimorbidity (PACE in MM) study is to reorient the health care system from a single disease focus to a multimorbidity focus; centre on not only disease but also the…
- Conditions
- Hypertension, Depression, Anxiety, Musculoskeletal Pain
- Trial name
- PACEinMM-QC (NCT02789800)
- Testing
- DIMAC02
- Where
- 2 sites in Canada
- Volunteers
- 284 people
- Sponsor
- Université de Sherbrooke
Alzheimer Disease, Dementia
Supporting Caregivers of Persons With Dementia: A Pilot Study
The purpose of this study is to pilot the home Environmental Skill-Building Program (ESP) and an educational control intervention with persons with dementia and their caregivers (n=40) in preparation for a larger double-blind…
- Trial name
- NCT00908492
- Testing
- Education Control, Environmental Skill Building
- Where
- Canada
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- McMaster University
Tourette Syndrome
Epidemiology of Assertiveness and Emotion Management Disorders in People With Tourette's Syndrome
The goal of this study is to evaluate the proportion of assertiveness difficulties in Tourette syndrome. Participants will complete several e-questionnaires (on assertiveness, Tourette severity, quality of life, self-esteem and…
- Trial name
- AFFIRMATICS (NCT06136572)
- Testing
- Rathus Assertiveness scale
- Where
- France
- Volunteers
- 350 people
- Sponsor
- University Hospital, Clermont-Ferrand
Primary Progressive Aphasia, Frontotemporal Dementia
Better Living With Non-memory-led Dementia
This is a feasibility study on the effects of an online-based training and education programme for carers of people with posterior cortical atrophy (PCA), primary progressive aphasia (PPA) and behavioural-variant frontotemporal…
- Conditions
- Primary Progressive Aphasia, Frontotemporal Dementia, Alzheimer Disease
- Trial name
- NCT05525377
- Testing
- Better living with non-memory led dementia course
- Where
- United Kingdom
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University College, London
Bipolar Disorder, Type II
Internet-based Cognitive Behaviour Therapy (CBT) for Persons Diagnosed With Bipolar II
The aim of the study is to test the feasibility and acceptability of internet-based Cognitive Behaviour Therapy (CBT) for persons diagnosed with bipolar disorder, type II.
- Trial name
- NCT01742351
- Testing
- Guided internet-based cognitive behavior therapy
- Where
- Sweden
- Volunteers
- 7 people
- Sponsor
- Örebro County Council
Alzheimer's Disease, Down Syndrome
Multicenter Vitamin E Trial in Aging Persons With Down Syndrome
The purpose of this study is to determine the safety and effectiveness of 2,000 international units of Vitamin E (alpha tocopherol)on cognitive function of aging persons with Down syndrome.
- Trial name
- NCT01594346
- Testing
- Alpha-Tocopherol, Sugar Pill
- Volunteers
- 349 people
- Sponsor
- New York State Institute for Basic Research
Mild Cognitive Impairment
Exploring Feasibility, Acceptability and Impact of Using Neurofeedback with Persons with Mild Cognitive Impairment
The goal of this pilot study is to determine the feasibility, acceptability and potential impact of using neurofeedback interventions to manage cognitive, emotional, and behavioural symptoms in individuals with mild cognitive…
- Trial name
- NCT06762522
- Testing
- Nonlinear dynamical neurofeedback (NLD), Low energy neurofeedback system (LENS), Brain Music
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Queen's University
Alcohol Use Disorder, Mental Health Disorder
Integrating Combined Therapies for Persons With Co-occurring Disorders
The purpose of this study is to assess the effectiveness and implementability of ICT for co-occurring alcohol use and mental health disorders within community addiction treatment, as delivered by routine community addiction…
- Trial name
- ICT (NCT02598518)
- Testing
- Integrating Combined Therapies, Standard Care
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Stanford University
Schizophrenia, Insulin Resistance
Salsalate for Insulin Resistance in Schizophrenia
Being obese is a common problem for people with schizophrenia. People with schizophrenia are more likely to be overweight compared to the general population.
- Trial name
- NCT01182727
- Testing
- salsalate
- Where
- 2 sites in United States
- Volunteers
- 13 people
- Sponsor
- University of Maryland, Baltimore
HIV/AIDS and Infections, Disorder Sleep
Quality of Life, Sleep, and Biomarkers in People With HIV/AIDS
Aim: Evaluate the influence of exercise, in different times, on quality of life, sleep and clinical parameters in people living with HIV/AIDS (PLHA). Methods: Intervention study, prospective.
- Conditions
- HIV/AIDS and Infections, Disorder Sleep, Lipodystrophy
- Trial name
- PLHA (NCT03445351)
- Testing
- Aerobic, resistance and concorrent.
- Volunteers
- 17 people
- Sponsor
- JULIANY DE SOUZA ARAUJO
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