Clinical trials: Persons With Psychiatric Disorders
Schizophrenia
Effects of Intranasal Oxytocin on Satiety Signaling in People With Schizophrenia
The objective of this study is to test a single dose of intranasal oxytocin, compared to placebo, in a within subjects, crossover design, to see if oxytocin will improve satiety signaling (behaviorally and/or by self report)…
- Trial name
- NCT01614093
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Maryland, Baltimore
Anxiety
Sensory Awareness Program
Few alternatives to addictive medical treatment exists for persons with severe mental health problems (SMHP) and anxiety, often connected to high risk of suicide.
- Trial name
- NCT06432114
- Testing
- Sensory Awareness Program (SAP), Treatment as usual (TAU)
- Where
- Sweden
- Volunteers
- 207 people
- Sponsor
- Lund University
Multiple Sclerosis, Nurse's Role
The Effect of Nurse Practitioner (NP-led) Care Upon Mood in People With Multiple Sclerosis
MS is the leading cause of non-traumatic disability in young adults. Canada and Alberta, have the highest prevalence of people with multiple sclerosis (PwMS) in the world.
- Trial name
- NCT04388592
- Testing
- Nurse Practitioner (NP) Led Care Arm
- Where
- Canada
- Volunteers
- 248 people
- Sponsor
- University of Alberta
Dementia, Alzheimer Disease
All About Me: An Intervention to Ease the Transition to Long Term Care
This Phase I study will involve initial development and evaluation of an innovative cross-platform software app called All About Me (AAM), which will consist of Serious Digital Health Games (SDHGs) for PWD.
- Conditions
- Dementia, Alzheimer Disease, Dementia, Vascular, Dementia, Mixed
- Trial name
- AAM (NCT05516134)
- Testing
- SAFE at Home
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Hopeful Aging
Alzheimer Disease
Investigating if a Stronger tDCS Intensity is More Effective for Improving Naming Ability in People Living With Alzheimer's Disease
There is currently little symptomatic therapy for Alzheimer's Disease (AD) and nothing effective for individuals with Frontotemporal dementia (FTD).
- Trial name
- NCT05509387
- Testing
- transcranial direct current stimulation and naming training
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- Baycrest
Sleep Disturbance, Dementia
Telephone-Coached Sleep Bibliotherapy for Dementia Caregivers
Sleep disturbances are common among informal caregivers of people with dementia and can negatively affect their physical and psychological well-being.
- Trial name
- NCT07826663
- Testing
- Telephone-Coached Sleep Bibliotherapy, Educational Booklet
- Where
- Hong Kong
- Volunteers
- 120 people
- Sponsor
- The Hong Kong Polytechnic University
Amputation, Depression
Self-Management Program for Persons With Limb Loss
The specific aims of this study are: 1. To develop and pilot a self-management (SM) intervention for persons with limb loss in a group setting using a participatory action research (PAR) strategy. 2.
- Conditions
- Amputation, Depression, Pain, Anxiety
- Trial name
- NCT00198692
- Testing
- self-management
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Schizoaffective Disorder, Schizophrenia
Effectiveness of a Mobile Texting Intervention for People With Serious Mental Illness
Testing an mHealth mobile interventionist texting program on illness management.
- Conditions
- Schizoaffective Disorder, Schizophrenia, Bipolar Disorder, Major Depressive Disorder
- Trial name
- NCT03062267
- Testing
- Mobile Interventionist
- Where
- 2 sites in United States
- Volunteers
- 49 people
- Sponsor
- University of Washington
Anxiety
A Randomised Feasibility Trial With Internet Based Self-help Therapy
Background. In Denmark, about 350,000 persons suffer from anxiety. Public health-care services plan to implement internet based self-help psychotherapy (IBT) to be an important alternative and supplement to ordinary face-to-face…
- Trial name
- IBT (NCT02499055)
- Testing
- FearFighter
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Transcutaneous Vagal Nerve Stimulation (tVNS), Prader-Willi Syndrome
Proof of Concept Study of Vagus Nerve Stimulation
The investigator's recent pilot study of vagus nerve stimulation (VNS) from a surgically implanted medical device to control the excess eating behaviour characteristic of Prader-Willi Syndrome (PWS) found that it was safe and…
- Trial name
- NCT03689621
- Testing
- Transcutaneous vagus nerve stimulation (tVNS)
- Volunteers
- 9 people
- Sponsor
- Jessica Beresford-Webb
Caregivers of People With Dementia, Quality of Life
Mindfulness-Based VR for Family Caregivers of People With Dementia
The goal of this clinical trial is to explore the effectiveness of mindfulness-based VR could enhance depression, sleep quality, and overall quality of life for family caregivers providing care for people with dementia.
- Trial name
- NCT06034249
- Testing
- Mindfulness-Based VR, Audio
- Where
- Taiwan
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Schizophrenia, Psychosis
Tele-group Cognitive Behavioural Family Intervention for People With Schizophrenia and Their Families (Feasibility tgCBFI)
This mixed-method study aims to examine the feasibility of delivering tgCBFI programme to dyads of people with schizophrenia and their family caregivers, and generate preliminary evidence on the effectiveness of tgCBFI in…
- Trial name
- NCT05808244
- Testing
- tgCBFI, Usual psychiatric care
- Where
- Hong Kong
- Volunteers
- 24 people
- Sponsor
- The Hong Kong Polytechnic University
Caregiver Burden, Alzheimer Disease
Reducing Burden in Care Partners of Community-Dwelling Persons With Dementia and Oropharyngeal Dysphagia
The goal of this clinical trial is to learn if a newly-created website tool, called WeCareToFeedDysphagia, helps to reduce feelings of burden in care partners of patients with Alzheimer's disease and related dementias (AD/ADRD)…
- Conditions
- Caregiver Burden, Alzheimer Disease, Dementia, Oropharyngeal Dysphagia
- Trial name
- NCT06557863
- Testing
- WeCareToFeedDysphagia web tool
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Northwell Health
Mild Cognitive Impairment (MCI), Dementia
Exercise Workshop, Skill-Based Art Approaches, and Awareness Studies for Elderly Individuals
Purpose: The aim of the project is to contribute to the physical, social, and psychological well-being of elderly individuals with cognitive impairment within a multidisciplinary approach framework, and to increase the level of…
- Conditions
- Mild Cognitive Impairment (MCI), Dementia, Alzheimer Disease, Geriatric Rehabilitation
- Trial name
- NCT07016893
- Testing
- Healthy aging interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Istanbul University - Cerrahpasa
Autism Spectrum Disorder (ASD
Effectiveness of DIR/Floortime™ in Children With Autism Spectrum Disorder
This randomized controlled trial evaluates the efficacy of Integrated DIR/Floortime™ in improving functional emotional development and adaptive behavior in children aged 4-12 years with Autism Spectrum Disorder (ASD).
- Trial name
- DIR-ASD (NCT07758465)
- Testing
- DIR/Floortime, Standard therapy
- Where
- Pakistan
- Volunteers
- 14 people
- Sponsor
- Fatima Tabassum
Psychiatric Hospitalization
Networked-Based Recovery With User Involvement
Introduction Over the past 20 years there has been an overall deterioration in the mental health of young people. An increasing number of young people are diagnosed with emotional disorders such as anxiety and depression.
- Trial name
- RENEW-S (NCT04097977)
- Testing
- An educational support model called RENEW (Rehabilitation for Empowerment, Natural Support, Education and Work) targeting young people with mental health difficulties.
- Volunteers
- healthy volunteers welcome
- Sponsor
- Psychiatric Research Unit, Region Zealand, Denmark
Frontotemporal Dementia, Behavioral Variant, Alzheimer Disease
Links Between Self-awareness and Sociocognitive Processes in Neurodegenerative Diseases
This monocentric, non-interventional study (SELFSOC) investigates the relationship between self-awareness and social cognition in patients with behavioral variant frontotemporal dementia (bvFTD) and Alzheimer's disease (AD).
- Trial name
- SELFSOC (NCT07531732)
- Testing
- Computer-based facial expression recognition task, Computerized affective task, UCLA Structured Insight Interview
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Depression, Anxiety
Improving Psychological Wellness After Acquired Brain Injury
The purpose of the study is to investigate the potential benefits of a psychological therapy, called cognitive behaviour therapy (CBT), for improving emotional well being after acquired brain injury and to demonstrate its…
- Conditions
- Depression, Anxiety, Brain Injury
- Trial name
- NCT00866632
- Testing
- Cognitive Behavioural Therapy
- Where
- 2 sites in Canada
- Volunteers
- 75 people
- Sponsor
- Toronto Rehabilitation Institute
Alexithymia, Alcohol Use Disorder
Impact of Art Therapy on Alexithymia in People With Alcohol Use Disorder
Art therapy support combined with standard care for people with an alcohol use disorder coming to a day hospital for withdrawal could be beneficial compared to standard care alone because it would improve the alexithymia of these…
- Trial name
- ALEXART (NCT04206930)
- Testing
- Art Therapy
- Where
- France
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Dementia
Caregiver Bootcamp
This study will assess the preliminary efficacy of a synchronous/asynchronous psychoeducation program designed to promote caregiving mastery in the immediate time period after a dementia diagnosis.
- Trial name
- NCT07006116
- Testing
- Synchronous/asynchronous online course
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Emory University