Clinical trials: Pervasive Development Disorders
Autism Spectrum Disorder, Healthy
Investigating the Clinical Utility of the Oxford Virtual Autism Assessment Tool (OVAAT)
The goal of the study is to evaluate a new Autism Spectrum Disorder (ASD) diagnostic tool (Oxford Virtual Autism Assessment Tool (OVAAT)) to see whether it can: Be able to identify autistic traits Be able to distinguish between…
- Conditions
- Autism Spectrum Disorder, Healthy, Neurotypical
- Trial name
- NCT06582290
- Testing
- Oxford Virtual Autism Assessment Tool (OVAAT)
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Oxford Health NHS Foundation Trust
Fetal Growth Restriction
A Randomized Air Filter Intervention Study of Air Pollution and Fetal Growth in a Highly Polluted Community
The purpose of this study is to use an air filter intervention to evaluate the relationship between particulate matter air pollution exposure during pregnancy and fetal growth.
- Trial name
- NCT01741051
- Testing
- HEPA Filter
- Where
- Mongolia
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Simon Fraser University
Autism Spectrum Disorders
Telehealth Coaching for Families of Children With Autism
The purpose of this study is to investigate the efficacy of a 12 week telehealth intervention for families of children with autism spectrum disorders under the age of 6 years on child participation and parent efficacy.
- Trial name
- NCT02928068
- Testing
- Occupational Performance Coaching (OPC)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Autism Spectrum Disorders
Brain Mechanisms for Language Processing in Adolescents With Autism Spectrum Disorder
The main goal of our study is to find out why some people with Autism Spectrum Disorder (ASD) do not develop verbal abilities or remain minimally-verbal throughout adolescence and adulthood.
- Trial name
- BSL (NCT02700074)
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Autism Spectrum Disorder
Autism Access Link for Early Referral and Treatment
Autism Access Link for Early Referral and Treatment [ALERT], the intervention proposed in this application, is a novel state-wide referral and case management platform that PCPs can activate to ensure that a child with suspected…
- Trial name
- Autism ALERT (NCT04861740)
- Testing
- Autism ALERT, Screening Intervention
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Autism Spectrum Disorder
A Novel Framework for Impaired Imitation in ASD
There is long-standing recognition that people with autism spectrum disorders (ASD) have difficulty imitating others' actions; some investigators have highlighted impaired imitation as being a core contributor to the development…
- Trial name
- NCT03423160
- Testing
- None--observational
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Autistic Disorder
A Chart Review to Evaluate the Safety and Efficacy of MeRT on Subjects With ASD
The purpose of this study is to evaluate the safety and efficacy of Magnetic EEG/ECG-Guided Resonance Therapy (MeRT) on subjects with Autism Spectrum Disorder (ASD).
- Trial name
- NCT02758496
- Testing
- MeRT Efficacy Chart Review
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Wave Neuroscience
Autism, Cerebral Palsy
Near-infrared Spectroscopy and Electroencephalography to Assess Cortical Activation During Motor Tasks in Infants and Toddlers With and Without Cerebral Palsy
Background: New ways to study the brain as people move include near-infrared spectroscopy (NIRS) and electroencephalography (EEG).
- Trial name
- NCT03434080
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Autism Spectrum Disorder
Emergence of Generative Language
The purpose of this study is to investigate the effects of several applied behavior teaching procedures on the use of multi-word utterances by children with autism.
- Trial name
- NCT02555241
- Testing
- Mand Training, Matrix, Stimulus Equivalence Training
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Emory University
Autism Spectrum Disorder
Feasibility of Using Telepractice to Provide Modified Interaction Guidance.
The purpose of this study is to determine the feasibility of using telepractice to provide Modified Interaction Guidance (MIG) to caregivers and their child with autism.
- Trial name
- NCT03972254
- Testing
- Modified Interaction Guidance
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Autism, Children
Biomarker of Children With Familial Autoimmune History
The purpose of this study is to identify biomarkers in this subset of autism patients, design a protein based assay system for screening serum for these biomarkers and confirm that these serum antibodies are still present at one…
- Trial name
- NCT01541033
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Le Bonheur Children's Hospital
Autism
Psychophysiological Effects of Lactobacillus Plantarum PS128 in Preschool Children With Autism Spectrum Disorder
Autism Spectrum Disorders (ASD) comprises a complex group of disorders of neuronal development characterized by social and communication impairment along with presence of repetitive and restrictive behaviors.
- Trial name
- NCT03982290
- Testing
- Probiotic, Lactobacillus plantarum PS128
- Where
- Taiwan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Autism Spectrum Disorders, Non-verbal Learning Disorder
Comparison of ABLLS-R and Portage Guide in the Development of Receptive Language Skills Autism Spectrum Disorder.
Language is the system someone uses to communicate with another person. This covers the origins and construction of words, their definitions, and the use of language in various contexts.
- Trial name
- NCT06292520
- Testing
- Portage Guide Protocol, ABLLS-R protocol
- Where
- Pakistan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Autism Spectrum Disorder
Evaluation of Social ABCs With Attention Training Intervention for Toddlers With Suspected Autism
The Social ABCs is an evidence-based, developmentally informed, caregiver-mediated behavioural intervention for toddlers with suspected or confirmed Autism Spectrum Disorder (ASD).
- Trial name
- NCT03215394
- Testing
- Attention Training Program, Social ABCs, Treatment As Usual
- Where
- 4 sites in Canada, United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Neurodevelopmental Outcomes, ADHD - Attention Deficit Disorder With Hyperactivity
Where Wild Things Grow: Nature- and Activity-based Group Interventions for Neurodivergent Children and Youth
The goal of this action research project is to develop and implement nature- and activity-based group interventions across health care, school and leisure settings in Southern Norway.
- Conditions
- Neurodevelopmental Outcomes, ADHD - Attention Deficit Disorder With Hyperactivity, Autism, Tourette Syndrome
- Trial name
- NCT07203469
- Testing
- Universal approach, Selective approach, Outdoor therapy
- Where
- 2 sites in Norway
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Sorlandet Hospital HF
Autism Spectrum Disorder
Open Label, Adaptive, Parallel Group PET Study Using RO7017773 And [11C] RO15-4513
This is a single dose (SD), non-randomized, open-label, adaptive, parallel group study with the purpose of investigating the occupancy of alpha5-containing GABAA receptors by RO7017773 in healthy participants.
- Trial name
- NCT03507569
- Testing
- RO7017773, [11C] Ro15-4513
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Autism Spectrum Disorder, Repetitive Compulsive Behavior
Family-Implemented Treatment on the Behavioral Inflexibility of Children With Autism
The overall goal of this project is to determine whether a new form of family-based treatment for repetitive and inflexible behaviors, delivered using videoconferencing technology, can counter any negative effects of those…
- Trial name
- FITBI (NCT05125003)
- Testing
- FITBI, Parental Education
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Autism Spectrum Disorder, Bone Diseases, Developmental
Bone Mass Accrual in Children With Autism Spectrum Disorder
This is a observational study to investigate the degree to which bone mineral density is impaired in boys with autism compared with typically developing controls.
- Trial name
- NCT03162445
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder
JASPER Implementation in NFLD
This study will focus on examining the supports required to enable community Senior JASPER Trainers to support the training and development of junior interventionists throughout the province of Newfoundland and Labrador, Canada.
- Trial name
- NCT03205475
- Testing
- Alternate Coaching and Video Feedback Phase 1, Weekly Coaching in Phase 1, Weekly Coaching plus Intensive Refresher Course Phase 2
- Where
- Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Government of Newfoundland and Labrador
Autism Spectrum Disorder
Can a Novel Telemedicine Tool Reduce Disparities Related to the Identification of Preschool Children With Autism?
Families seeking evaluation for autism spectrum disorder (ASD) often face barriers such as low availability of specialists, lengthy waitlists, and long distances to tertiary care diagnostic centers.
- Trial name
- TAP-P (NCT05373173)
- Testing
- Tele-assessment + In-person assessment, Tele-assessment only
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center