Clinical trials: Pervasive Development Disorders
Autism Spectrum Disorder
Partners in School: Promoting Continuity Across Home and School
Partners in School is a collection of implementation strategies (e.g., communication training, problem-solving consultation) to help parents/primary caregivers and teachers of children with autism spectrum disorder implement the…
- Trial name
- NCT05154981
- Testing
- Education communication skills (ECS) training, Partners in School
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Autism
Autism in Adult Patients and the Effects on Caregivers
Background: The number of adults with autism is expected to rise significantly in the near future, due to two main reasons: First, a dramatic increase in the estimates of the prevalence of autism starting in the mid 1980s…
- Trial name
- NCT00367107
- Where
- Israel
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder
Motor Impairments in Children With Autism Spectrum Disorder: a Multimodal Approach
The general goal of the present proposal, Progetto MOSAICO, is the identification of a multimodal panel of neuropsychological, kinematic, neurophysiological, and genetic markers associated with motor abnormalities present in ASD.
- Conditions
- Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder, Intellectual Disability
- Trial name
- MOSAICO (NCT04769011)
- Testing
- Clinical evaluation, Neuropsychological evaluation, Neurophysiological evaluation
- Where
- Italy
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Autism Spectrum Disorder
Cannabidiol (CBD) in Adults With ASD
There are no FDA approved treatments for use in adults with autism spectrum disorder (ASD), many of whom have distressing anxiety, mood disturbances, sleep problems, and agitation.
- Trial name
- NCT05015439
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Autism, Autism Spectrum Disorder
Comparing Imitation and Stereotyped Behaviors in Autistic Children: Robots vs. Human Operators
Virtual QT is a social robot designed to interact with humans in social and educational contexts. Equipped with visual and vocal interfaces, the robot can recognize and respond to various human inputs, providing emotional support…
- Trial name
- NCT06144528
- Testing
- QT robot
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Autism
Investigation of Neuroserpin as an Autism Candidate Gene
Previously it has been shown that Familial Encephalopathy with neuroserpin inclusion bodies (FENIB) patients develop abnormalities that partially overlap with Autism Spectrum disorders (ASD), confounded with additional features…
- Trial name
- NCT00917683
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Autistic Disorder
Associative Memory in Autism Spectrum Disorder
The aim of this study is to investigate the neural substrates of associative memory in Autism Spectrum Disorder using both behavioural and EEG assessments.
- Trial name
- MEM-TA (NCT02265094)
- Testing
- Electroencephalography, Neuropsychological assessment
- Where
- France
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Autism-Spectrum Disorder, Conduct Disorder
Investigating the Specificity of Neural Correlates for Emotion Processing Deficits in Conduct Disorder and Autism Spectrum Disorders
This study is 1. to investigate the differential and shared neural underpinnings of facial emotion processing within Conduct disorder (CD) and Autism-Spectrum disorder (ASD) and 2.
- Trial name
- NCT04324099
- Testing
- neuroimaging session (with simultaneously acquired eye-tracking), Questionnaire (for children) assessing traumatic experiences (Childhood trauma questionnaire (CTQ)), Social and Health Assessment (SAHA) questionnaire (for children)
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Autism Spectrum Disorder
Investigation of Brain Plasticity in Autism Spectrum Disorders
Individuals with autism spectrum disorders (ASD) commonly experience variances in tactile behaviors, such as hypersensitivity to light touch stimuli, altered texture discrimination, and hyporesponsivity to pain.
- Trial name
- NCT04706364
- Testing
- Neuropsychological Testing, (Optional) Saliva Collection, Sensory Testing
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Autism, Autism Spectrum Disorder
SenseToKnow Autism Screening Device Validation Study
This is a pivotal, prospective, double-blind, study to evaluate the sensitivity and specificity of the SenseToKnow device for the detection of autism spectrum disorder in children 16-36 months of age.
- Trial name
- NCT05874466
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Duke University
Autism Spectrum Disorder
Autism Biomarker Consortium for Clinical Trials
This is a multicenter longitudinal study that aims to identify, develop and validate a set of measures that can be used as stratification biomarkers and/or sensitive and reliable objective measures of social impairment in autism…
- Trial name
- ABC-CT (NCT02996669)
- Where
- United States
- Volunteers
- 399 people, healthy volunteers welcome
- Sponsor
- Yale University
Physical Inactivity, Sedentary Behavior
ASDactive: An Integrated Theory-based Intervention to Promote Habitual Physical Activity
ASDactive is a theory-based behaviour change intervention aimed at improving the physical activity behaviours of autistic youth.
- Conditions
- Physical Inactivity, Sedentary Behavior, Autism, Autism Spectrum Disorder
- Trial name
- ASDactive (NCT05958680)
- Testing
- ASDactive
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aberystwyth University
Autism, Asperger's Syndrome
Cognitive Behavioral Therapy for Anxiety Disorders in Adolescents With Autism
Due to the considerable prevalence of anxiety in youth with autism spectrum disorders, this study seeks to establish the efficacy of a modified cognitive behavioral therapy protocol in 50 adolescents versus other available…
- Conditions
- Autism, Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified, Generalized Anxiety Disorder
- Trial name
- NCT01563003
- Testing
- Cognitive Behavioral Therapy, Treatment as usual
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Autism, Attention Deficit Hyperactivity Disorder
a2 Milk for Autism and Attention-deficit Hyperactivity Disorder (ADHD)
Under double-blind, placebo-controlled, cross-over conditions, the short-term effects of use of A1 beta casein free milk (a2 milk) and milk containing A1 beta casein will be compared in a sample of pre-pubescent boys diagnosed…
- Conditions
- Autism, Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder
- Trial name
- A2MT (NCT02911194)
- Testing
- a2 milk, a1 containing milk
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Autism
Brain Plasticity of Autism in Response to Early Behavioral Intervention: A Multimodal MRI Study
Autism is a well-recognized neurodevelopmental disorder severely affecting the health of children. While the unclear neurobiological basis of autism and the lack of effective medication, the most commonly used approach for…
- Trial name
- NCT02807766
- Testing
- Behavior modification, Behavior modification and sensory integration training, Behavior modification and applied behavioral analysis
- Where
- 2 sites in China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Autism Spectrum Disorder
The Effect of Hepatic Impairment on the Pharmacokinetics of Balovaptan
This is a multi-center, non-randomized, open-label, parallel group, multiple-dose study to assess the pharmacokinetic, safety, and tolerability of balovaptan in male and female subjects with moderate hepatic impairment compared…
- Trial name
- NCT03912350
- Testing
- Balovaptan
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Autism Spectrum Disorders, Normal Hearing
The Effects of ProFoveate on Reducing Self-Stimulating Behaviors
This study is designed to pilot an intervention technique to reduce the self-stimulating behaviors seen in individuals with autism spectrum disorders using intervention with ProFoveate pellets.
- Conditions
- Autism Spectrum Disorders, Normal Hearing, Normal Intelligence, Exhibit Self- Stimulating or Ritualistic Behaviors
- Trial name
- NCT02088047
- Testing
- ProFoveate
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Autism Spectrum Disorder (ASD), Joint Attention Impairment
Social Attention in ASD and TD Children
To examine whether the spatiotemporal organization of gaze strategies differs between children with autism spectrum disorder (ASD) and typically developing (TD) children during a staged joint attention interaction, and to…
- Trial name
- NCT07583615
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Autism Spectrum Disorder, Disruptive Behavior
Iterative Redesign of a Behavioral Skills Training Program for Use in Educational Settings
This study proposes to redesign the RUBI Parent Training program, a low-intensity intervention for youth with autism spectrum disorder and disruptive behavior, for use by school personnel in the classroom.
- Trial name
- NCT04199533
- Testing
- RUBI, RUBIES
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Washington
Anxiety Acute, Stress
Drumming Groups for Parents of Autistic Children
This project aims to encourage a sense of belonging, community, and emotional support for parents of autistic children through a group drumming (music therapy) intervention.
- Conditions
- Anxiety Acute, Stress, Depression and Quality of Life, Stress in Parents of Autistic Children
- Trial name
- DG_PAC (NCT07375043)
- Testing
- Group Drumming
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Arizona State University