Clinical trials: Pervasive Development Disorders
Autism Spectrum Disorders
Structural Connectivity as Imaging Endophenotypes of Autism Spectrum Disorders
Autism spectrum disorders (ASD) is a highly hereditary neuropsychiatric disorder. In children and adolescents worldwide, the prevalence of ASD is estimated at 0.6%.
- Trial name
- NCT01513629
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder, Autism
Feasibility of Mobile Game System for Potential Treatment of Developmental Delays
The investigators will test the feasibility and preliminary efficacy of a Mobile game system meant to generate valuable data for measuring progress and building novel artificial intelligence models while delivering impactful…
- Trial name
- NCT04909710
- Testing
- Mobile Game System for Potential Treatment of Developmental Delays
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stanford University
Autism Spectrum Disorder, Motor Activity
rTMS to Improve Motor Function in Autism
In the current project, investigators have two main goals: i) Testing whether an excessive plasticity, i.e. hyperplasticity in the motor cortex underlies motor function difficulties in autistic adults, and ii) Using repetitive…
- Trial name
- (AMBLE Autism) (NCT06497920)
- Testing
- Active rTMS to the motor cortex
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Autism Spectrum Disorder
Motor Intervention, Motor Skills, and Dual Task in ASD
This study is designed to understand whether a structured movement (motor) program can help improve movement skills and daily functioning in young children with autism spectrum disorder (ASD).
- Trial name
- NCT07386106
- Testing
- Motor Support Program
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Autism
TMS Measures of Plasticity and Excitatory/Inhibitory Ratio as Biomarkers: R-baclofen Effects in Normal Volunteers
Our overall objective is to apply Transcranial Magnetic Stimulation (TMS) to develop measures of human synaptic plasticity and of brain excitatory:inhibitory ratio (E:I ratio), which we propose as novel biomarkers and outcome…
- Trial name
- NCT01172509
- Testing
- R-baclofen
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Gonzalez-Heydrich, Joseph, M.D.
Autism Spectrum Disorder
Cognitive Support Technology for Postsecondary Students With Autism Spectrum Disorder
This study will fill important knowledge gaps in the availability of best practices that use innovative methods to integrate the cognitive and vocational needs of students with Autism Spectrum Disorder (ASD) who will be…
- Trial name
- NCT04980963
- Testing
- Cognitive Support Technology (CST)
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kent State University
Schizophrenia, Autism Spectrum Disorder
Dyad Oxytocin Study (DOS)
The purpose of the investigators proposed study is twofold: 1) To investigate the role of the affiliative neuropeptide oxytocin in unhealthy interactions in families of patients with schizophrenia and families of patients with…
- Trial name
- DOS (NCT02302209)
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Autism Spectrum Disorder, Child Safety
ESCAPE Kits for Elopement Prevention in Children With Autism
This study will evaluate elopement prevention kits for children with autism spectrum disorder who exhibit elopement behavior such as dashing or wandering away from safe settings.
- Conditions
- Autism Spectrum Disorder, Child Safety, Caregiver Stress
- Trial name
- NCT07225907
- Testing
- Elopement Prevention Kits
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Autism Spectrum Disorder
Satisfaction Rates Among Parents of Children With Autism in the ED
This study is a randomized controlled trial utilizing a patient-centered questionnaire distributed to parents of children with autism.
- Trial name
- ASD (NCT02675933)
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Seton Healthcare Family
Autism Spectrum Disorder, Attention Deficit Disorder With Hyperactivity (ADHD)
Pai.ACT: AI-Driven ACT Chatbot for Mental Health Triage and Service Evaluation
Parents of children with special needs in Hong Kong often face limited psychological support, which can negatively impact the child rehabilitation process and the well-being of parent-child relationships.
- Conditions
- Autism Spectrum Disorder, Attention Deficit Disorder With Hyperactivity (ADHD), Neurodevelopmental Disorder (Diagnosis), Dyslexia
- Trial name
- NCT06808555
- Testing
- Pai.ACT Group, Control Group
- Where
- 20 sites in Hong Kong
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Autism, Attention Deficit Disorder With Hyperactivity
Methylphenidate for Attention Deficit Hyperactivity Disorder and Autism in Children
This study examined the cognitive and behavioral differences in children who have an autism spectrum disorder (ASD) with or without additional symptoms of ADHD.
- Trial name
- NCT00178503
- Testing
- Methylphenidate-extended release, Methylphenidate-immediate release
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Autism Spectrum Disorder, Neurodevelopmental Disorders
Early Detection and Referral for Autism and Neurodevelopmental Disorders at the Maternal and Child Protection Services
This study aims to compare two screening strategies for identifying infants with a potential risk of Autism Spectrum and Neurodevelopmental Disorders to provide early access to care and increase the likelihood of a favorable…
- Trial name
- NCT05815095
- Testing
- PREAUT grid
- Where
- France
- Volunteers
- 10,400 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Autism Spectrum Disorder
Facebook for Social Skills Training in Autism: Project Rex Connect
Twelve participants were randomized to either a Facebook group or a book club group for six weeks. Data was collected on the participants social and behavioral function at both the start and the conclusion of the intervention.
- Trial name
- FBREX (NCT02897687)
- Testing
- Facebook Group, Book Club Group
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Autism Spectrum Disorder, Behavior
The Effects of Exercise on Behavior and Fitness in Children With ASD
This study will examine the effects of a school based exercise intervention programme on the behaviour and fitness levels in children with autism.
- Trial name
- NCT04047615
- Testing
- Exercise
- Where
- Ireland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- South East Technological University
Chronic Pain, Chronic Pain Syndrome
Outcomes Mandate National Integration With Cannabis as Medicine
This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Chronic Pain Due to Injury, Chronic Pain Due to Trauma
- Trial name
- OMNI-Can (NCT03944447)
- Testing
- Cannabis, Medical, RYAH-Medtech Inhaler
- Where
- 17 sites in United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- OMNI Medical Services, LLC
Autism Spectrum Disorder
Participant(s) With Autism and High Pain Tolerance Treated With High Dose Naltrexone
High dose naltrexone with response gauged by pain tolerance as measured by the cold pressor test may help treat autism.
- Trial name
- NCT05100563
- Testing
- 50 mg naltrexone
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Autism Spectrum Disorder, Neurodevelopmental Disorders
Evaluation of a Novel Intervention for Infants At Risk for Neurodevelopmental Disorders
This study entails a "proof of concept" evaluation of a novel intervention, Parents and Infants Engaged (PIE), for prodromal infants at-risk for neurodevelopmental disorders (NDs).
- Trial name
- PIE (NCT03388294)
- Testing
- Parents and Infants Engaged
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Autistic Disorders Spectrum, Adhd
Studies of Brain and Body Interaction
The goal of this study is to characterize biophysiolgoical signals as a comprehensive profile of the nervous systems in order to understand interactions between the brain and body, while an individual performs naturalistic…
- Conditions
- Autistic Disorders Spectrum, Adhd, Asperger Syndrome, Alzheimer Disease
- Trial name
- NCT03672266
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rutgers University
Autism Spectrum Disorder, Intellectual Disability
TMS for the Investigation of Brain Plasticity in Autism Spectrum Disorders
The main purpose is to study brain plasticity (the changes that occur in the brain through experience) in individuals with autism spectrum disorder (ASD).
- Trial name
- NCT02836405
- Testing
- Transcranial Magnetic Stimulation
- Where
- 2 sites in United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Neurodevelopmental Disorders, Autism Spectrum Disorder (ASD)
Pai.ACT - An Artificial Intelligence Driven Chatbot Assisted ACT (Full Scale RCT)
Interventions for parents of children with NDD face two pivotal challenges. Firstly, many overlook the consequential influence of parenting stress, symptoms of parental anxiety and depression on the well-being of parent-child…
- Conditions
- Neurodevelopmental Disorders, Autism Spectrum Disorder (ASD), Attention Deficit Disorder With Hyperactivity (ADHD)
- Trial name
- NCT06779422
- Testing
- Pai.ACT, Positive parenting advice
- Where
- Hong Kong
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong