Clinical trials: Pervasive Development Disorders
Autism Spectrum Disorder, Neurodevelopmental Disorders
School-based Paraeducator Education for Engagement at Recess
The purpose of the proposed three-site study is to test whether an educator-level implementation strategy, coaching, with or without a school-level implementation strategy, school-based teams, will maximize paraeducators' use…
- Trial name
- SPEER (NCT06559267)
- Testing
- Remaking Recess, TEAM
- Where
- 3 sites in United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Washington
Autism Spectrum Disorder, Adverse Childhood Experiences
Assessing the Gut Microbiome and Its Association With Pediatric Stress and Cognition
Using a metabolomics approach in combination with eye-tracking data, this research study proposes to gather evidence from two interrelated body systems (gut and brain) in order to assess how the microbiome is involved in stress…
- Conditions
- Autism Spectrum Disorder, Adverse Childhood Experiences, Stress Reaction
- Trial name
- NCT06269614
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Biospecimen Donation, Brain Injury
University of Central Florida CereBank
Millions of persons are affected by brain diseases. The CereBank will be used to support research studies aimed at improving the diagnosis and treatment of brain diseases.
- Conditions
- Biospecimen Donation, Brain Injury, Brain Diseases
- Trial name
- NCT06876857
- Where
- United States
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Autism Spectrum Disorder, Asperger Disorder
Understanding the Effects of Intervention on the Brain in Autism
This study examines how the PEERS (Laugeson \& Frankel, 2010; Laugeson, 2016) social-behavioral intervention affects social relationships and brain development and function in autistic preschoolers, adolescents, and young adults.
- Conditions
- Autism Spectrum Disorder, Asperger Disorder, PDD-NOS, Autism
- Trial name
- NCT02680015
- Testing
- PEERS
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Marquette University
Autism Spectrum Disorder, Autism
Advocating for Supports to Improve Service Transitions
This is a randomized intervention study to develop and test the national curriculum of a parent intervention training targeting parent's ability for advocate for services to improve the transition to adulthood for their youth…
- Trial name
- ASSIST (NCT04173663)
- Testing
- ASSIST
- Where
- 3 sites in United States
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Autism With High Cognitive Abilities, COVID-19 Pandemic
The Impact of Covid-19 Pandemic On The Children With Autism Spectrum Disorder
The Covid-19 outbreak has caused families and individuals to change their life routines and eating habits, and has affected their psychology, especially for children with autism, due to the change in their routines.
- Trial name
- NCT05197634
- Testing
- Not Applicable (observation)
- Where
- Turkey (Türkiye)
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Autism Spectrum Disorder, Anxiety
CBT for Anxiety in Children With Autism
This is a randomized controlled trial of Cognitive Behavioral Therapy (CBT) versus Psychoeducation and Supportive Therapy (PST) in children with Autism Spectrum Disorder and moderate to severe anxiety.
- Trial name
- NCT02725619
- Testing
- CBT, PST
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Yale University
Autism Spectrum Disorders
A Comparative Study of Driving Performance Among Adolescents With Autism Spectrum Disorder and Neurotypical Adolescents
The primary objective of this study is to compare the number of driving errors made by novice adolescents (0-5 hours of driving instruction) with ASD to those made by neurotypical adolescents during a standardized driving…
- Trial name
- Perf-TSA (NCT07630298)
- Testing
- Assessment of executive functions and attention, Evaluation on a driving simulator, Evaluation on-road
- Where
- France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Hopital La Musse
Autism Spectrum Disorder
Study of the Visual Perception During Emotional States on Subjects With an Intrusive Disorder of the Development
The Pervasive Developmental Disorders (PDD) are severe neurodevelopmental disorders, affecting nearly 1% of the general population.
- Trial name
- VisioTED (NCT02827279)
- Testing
- emotional induction
- Where
- France
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Autism, Autism Spectrum Disorder
Services to Enhance Social Functioning in Adults With Autism Spectrum Disorders
The purpose of this study is to test a novel, three-part cognitive behavioral treatment strategy to improve social functioning in adults with autism spectrum disorder.
- Conditions
- Autism, Autism Spectrum Disorder, Autistic Disorder, Asperger Syndrome
- Trial name
- NCT04788537
- Testing
- Training to Understand and Navigate Emotions and Interactions (TUNE In)
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Autism Spectrum Disorder
Procedure Sedation With Dexmedetomidine in Children With Autism Spectrum Disorders During Magnetic Resonance Imaging
Autism spectrum disorders (ASD) is a neurodevelopmental disorder and is characterized by functional impairment in social communication, restricted interests, and repetitive behaviors.The children with ASD has been shown different…
- Trial name
- NCT03597477
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Autism Spectrum Disorder
Insecure Attachment and Psychosocial Functioning in Autistic Adults Are Mediated by Depression and Paranoid Ideation
The present study examines if depressive symptoms, paranoid ideation, and emotion regulation strategies mediate the relationship between attachment and psychosocial functioning in autistic adults.
- Trial name
- NCT06030167
- Testing
- Insecure attachment and psychosocial functioning in autistic adults
- Where
- Netherlands
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Parnassia Groep
Autism Spectrum Disorder
Exosomal MicroRNA Expression in Children With Autism Spectrum Disorder
There is accumulating evidence that genetic expression plays a role in autism spectrum disorder, but the regulation of such genes is poorly understood.
- Trial name
- NCT01749670
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Autism, Psychotic Disorders
Brain and Oculometric Markers of Emotional Facial Expression Recognition Deficits
Disorders in the recognition of emotional facial expressions are part of the social cognition disorders described in several diseases.
- Trial name
- FERmarkers (NCT05501405)
- Testing
- Electroencephalogram and eye-tracking recordings
- Where
- France
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Autism Spectrum Disorder
Examining an Adaptive Telehealth Intervention
The purpose of this study is to explore the acceptability and effects of internet-based approaches for helping parents learn early intervention strategies (e.g., methods or tips for improving a child's behavior and development).
- Trial name
- NCT03840642
- Testing
- Mirror Me, Remote Coaching
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Autism, Development Delay
Culturally-Responsive Curriculum for Caregivers With Children at Autism Likelihood
The goal of this clinical trial is to examine how helpful and relevant the Family Care Project workbook is for families from culturally and linguistically diverse backgrounds who have a young child at autism likelihood.
- Trial name
- NCT06314438
- Testing
- Family Care Project
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Washington
Autism Spectrum Disorder
Neurocognitive and Psychosocial Outcome of Youths With Autism Spectrum Disorder
Autism spectrum disorders (ASD) is a common childhood-onset, multi-factorial, highly heritable, clinically and genetically heterogeneous, neurodevelopmental disorder.
- Trial name
- NCT02233348
- Where
- Taiwan
- Volunteers
- 523 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder (ASD), Intellectual Disability
Emotion Intensity Modulates Intention in ASD
This study used eye-tracking to examine how emotional expression intensity (low/medium/high) influences intention understanding in children with ASD, PDD, and TD during a puzzle-search task.
- Trial name
- NCT07597655
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Attention Deficit Hyperactivity Disorder (ADHD), Autism
The TEAM Study - Treatment Efficacy for Autism/Attention Using Mixed Amphetamine
The investigators are conducting a 10-week brain imaging and medication study. They are doing the research to study the response of Attention-Deficit/ Hyperactivity Disorder (ADHD) in youth with Autism Spectrum Disorder (ASD) on…
- Conditions
- Attention Deficit Hyperactivity Disorder (ADHD), Autism, Autism Spectrum Disorder
- Trial name
- NCT06853665
- Testing
- Adderall XR (mixed salts amphetamine)
- Where
- United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Gagan Joshi
Autism Spectrum Disorder
Social Motivation Intervention for Children With Autism Spectrum Disorder: Improving Peer Initiation
The purpose of this study is to investigate whether a social initiation motivation intervention (SIMI) focused on training children with ASD to initiate to peers during structured play activities will result in more frequent…
- Trial name
- NCT02360449
- Testing
- Social Initiation Motivation Intervention
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Stanford University