Clinical trials: Pervasive Development Disorders
Autism
Nutritional and Dietary Treatment Study for Children/Adults With Autism
70 children and adults with autism spectrum disorders will be enrolled in a 1-year, single-blind treatment study. Assessments will be conducted at the beginning and end of the study, including measurements of nutritional…
- Trial name
- NCT02059577
- Testing
- Nutritional and Dietary Interventions
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Autism Spectrum Disorder
Cognitive and Emotional Processing of Social Stimuli in Children and Youth With Autism Spectrum Disorder
Children and youth diagnosed with autism spectrum disorder (ASD) have been shown to react abnormally to social stimuli, especially to human faces.
- Trial name
- NCT01322984
- Testing
- Pictures, Startle eliciting noise
- Where
- Norway
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Tromso
Autism Spectrum Disorders
Emotional and Change-related Attention in Autism
Several studies seem to indicate that emotional attention and change-related attention are impaired in ASD. The goal of this study is to identify the relationships between those two types of automatic attention in visual and…
- Trial name
- AUTATTEN (NCT02160119)
- Testing
- MRI-based techniques, EEG
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Autism, Language Acquisition
Study of Toddlers With Language Delay
The purpose of this study is to learn more about risk factors for autism by studying the behavior and brain functioning of toddlers with early communication delays and typically developing toddlers.
- Conditions
- Autism, Language Acquisition, Language Development, Toddlers
- Trial name
- NCT01339767
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Autism, Autism Spectrum Disorder
Trial of Suvorexant for Sleep in Children With Autism
The purpose of this study is to examine the effect of suvorexant on sleep in children and adolescents with Autism Spectrum Disorder (ASD).
- Trial name
- NCT05546554
- Testing
- Suvorexant
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Stanford University
Autism Spectrum Disorder
Measuring Brain Inflammation in Autism
Autism spectrum disorders (ASD) are highly disabling, persistent neurodevelopmental disorders. There are no available treatments for core symptoms of ASD or biologically-based clinical biomarkers.
- Trial name
- NCT03117530
- Testing
- Minocycline
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Autism Spectrum Disorder
Interactive Mirroring Games wIth sOcial Robot (IOGIOCO) and Robotic System Adapted Into a Clinical Scale (RISCALE)
Background: The importance of early intervention in Autism Spectrum Disorders (ASD) has been widely demonstrated, and developmental trajectories in ASD highlight the importance of nonverbal communication, such as intransitive…
- Trial name
- RISCALE (NCT06855446)
- Testing
- Intervention with social robot NAO, Treatment as usual
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Autistic Disorder
Building Social Skills With Interdisciplinary Process Drama in ASD
This is a one group pre-post feasibility study of an interdisciplinary (theatre, Occupational Therapy (OT) and Speech Language Pathology (SLP)) intervention targeted at social skill development in children, aged 3-4.
- Trial name
- NCT03536351
- Testing
- Interdisciplinary process drama
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Utah
Schizophrenia / Schizoaffective Disorder, First Episode Psychosis (FEP)
French Minds Cohort: a French Longitudinal and Multimodal Cohort of Patients With Major Mood Disorders, Psychotic Disorders, Autism Spectrum Disorders, and Healthy Controls
The goal of this study is to learn whether people living with severe psychiatric disorders can be grouped into more homogeneous subgroups, across usual diagnostic categories, based on two key dimensions: social withdrawal and…
- Conditions
- Schizophrenia / Schizoaffective Disorder, First Episode Psychosis (FEP), Bipolar Disorder (BD), Major Depressive Disorder (MDD
- Trial name
- FRENCH-MINDS (NCT07881016)
- Testing
- 3T Brain MRI, Biological Sampling, Clinical, Cognitive and Digital Assessments
- Where
- 17 sites in France
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Fondation FondaMental
Autism, Autism Spectrum Disorder
Cerebellum and Autism: Regional Specialization for Social and Executive Functions
The goal of this study is to determine the impact of neuromodulation to the cerebellum on social and executive functions in neurotypical young adults and young adults with autism.
- Trial name
- NCT05396352
- Testing
- Transcranial direct current stimulation
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- American University
Autism
Parent Language Intervention for Autism
Improving social communication outcomes for children with autism spectrum disorders (ASD) has important public health implications.
- Trial name
- NCT02632773
- Testing
- Responsive Intervention, Directive Intervention
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Autism, Stress
5Minutes4Myself: A Wellness Program for Caregivers
This research study refines a wellness program designed for caregivers of autistic children called 5Minutes4Myself and further investigates its feasibility.
- Conditions
- Autism, Stress, Autism Spectrum Disorder
- Trial name
- NCT03771001
- Testing
- Motivational Interviewing coaching and habit-building app
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Physical Activity, Motor Skills Development
Feasibility and Acceptability of a Co-produced Intervention to Improve Physical Activity and Motor Competence Amongst Children With Intellectual Disabilities and/or Autism Spectrum Disorder: Movement Matters
The goal of this observational study is to find out whether an intervention designed to improve physical activity levels and movement skills is practical and acceptable for children aged 7-11 years with intellectual disabilities…
- Trial name
- MM (NCT07456514)
- Testing
- Movement Matters
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Autistic Disorder
A Trial to Assess the Efficacy and Safety of Medical Grade Cannabis in Children Diagnosed With Autism Spectrum Disorder
This single center, double-blinded, randomized, placebo-controlled crossover trial will assess the efficacy and safety of extraction of cannabis flowers dissolved in olive oil (30% CBD and 1.5% Δ9-THC) vs.
- Trial name
- NCT05413187
- Testing
- Medical Grade Cannabis oil
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- TO Pharmaceuticals
Autism Spectrum Disorder
A Collaborative Public/Private Employment Training and Placement Model ASD Transition Age Youth With Autism Spectrum Disorder (ASD)
The aim of the research project is to conduct evidence-based research on a nationally known vocational rehabilitation (VR) service model (Project Search) for individuals with Autism Spectrum Disorders (ASD).
- Trial name
- ProjSEARCH1 (NCT02360332)
- Testing
- Project SEARCH plus ASD Supports
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Autism, Challenging Behavior
Testing a Measurement Feedback App to Improve Data Quality, Supervision & Outcomes in Behavioral Health
The goal of this clinical trial is to test whether a smartphone-based data collection and feedback application ("Footsteps") improves the quality of behavioral data collected by one-to-one aides and leads to better youth mental…
- Conditions
- Autism, Challenging Behavior, ADHD, Oppositional Defiant Disorder
- Trial name
- Footsteps (NCT07042347)
- Testing
- Behavioral economics strategies, Electronic platform
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Autism Spectrum Disorder
The Therapeutic Effects of Intermittent Theta Burst Stimulation in Autism Spectrum Disorder
The investigator would like to investigate the impact of theta burst stimulation over right inferior frontal gyrus in autism spectrum disorder
- Trial name
- NCT04987749
- Testing
- intermittent theta burst stimulation
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Autism Spectrum Disorder
Effectiveness of the Care Coordination, Assessment, and Responsive Engagement Program for Transition-aged Adolescents (t-CARE) With ASD
An analysis of data for adolescents and young adults diagnosed with Autism Spectrum Disorders (ASDs) who are evaluated as part of the Care Coordination, Assessment, and Responsive Engagement for transition-aged adolescents…
- Trial name
- t-CARE (NCT03019952)
- Testing
- Care Coordination Visit
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Cognitive Function 1, Social
Social Cognition Assessment in Young Adults
The primary objective of this study is to determine the efficacy and feasibility of a battery of neuropsychological measures evaluating social cognition and behavior in young adults diagnosed with schizophrenia, autism spectrum…
- Trial name
- NCT02922400
- Testing
- Social Cognition Assessment and Training
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Autism Spectrum Disorder, Autism
Achieving Steady Work Among Adults With Autism Through Specialized Employment Program
Individuals with autism spectrum disorder (ASD) have significantly higher levels of unemployment and underemployment compared to their typically developing peers and all other groups with neurodevelopmental disorders, even though…
- Trial name
- NCT04107064
- Testing
- NaW, NaW-DS
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lawrence Fung