Clinical trials: Pervasive Development Disorders
Autism Spectrum Disorder
Assessing the Effectiveness of Reciprocal Imitation Teaching in Part C Early Intervention Settings (Sprout Study)
Despite strong consensus that early, specialized intervention for children with Autism Spectrum Disorder (ASD) can have a dramatic impact on outcomes, the public health system's capacity to provide such services is severely…
- Trial name
- NCT05425277
- Testing
- Reciprocal Intervention Teaching (RIT), Daily Routines
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Washington
Attention Deficit Hyperactivity Disorder (ADHD), Autism Spectrum Disorder (ASD)
Exploring Eye Vergence Markers ADHD) and ASD
The investigators study aims to evaluate the utility of eye vergence, an eye-tracking measure, as an indicator of visuo-spatial attention in children aged 4-17 years and adults, using computer-based eye-tracking tasks.
- Trial name
- NCT06885060
- Testing
- BGaze ADHD Diagnostic Test, Oddball/Alerting Computer Task, Facical Emotion Computer Task
- Where
- 3 sites in Spain, United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Elizabeth Kilbey
Autism Spectrum Disorders
Virtual Reality Social Cognition Training for Adults With Autism Spectrum Disorders
The purpose of this study is to predict and explain on the basis of brain function and structure the behavioral and brain effects of an evidence-based intervention for adults with high-functioning autism, Virtual Reality-Social…
- Trial name
- NCT02139514
- Testing
- Virtual Reality Social Cognition Training
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Yale University
Autism Spectrum Disorder
Shifting Brain Excitation-Inhibition Balance in Autism Spectrum Disorder
This study investigates brain response to single acute dose of cannabidiol, cannabidivarin, and placebo in healthy men with and without autism spectrum disorder
- Trial name
- NCT03537950
- Testing
- PLC, CBD, CBDV
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- King's College London
Autistic Disorder
Characterisation of Circadian Rhythm in Autistic Spectrum Disorder
Autism spectrum disorders (ASDs) are complex neurodevelopmental conditions characterized by deficits in social communication, delay in language and repetitive behaviors.
- Trial name
- NCT01984944
- Testing
- Autistic functional exploration, Control functional exploration
- Where
- France
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Psychiatric Disorder
Familial and Functional Study of Genetic Variants Identified in People With Schizophrenia, Bipolar Disorder, Autism Spectrum Disorder or Resistant Depression
Genetic analyses conducted on patient with psychiatric disorders assessed at the expert centres resulted in the identific action of genetic variants associated with psychiatric disorders (Courtois, 2020).
- Trial name
- GENI (NCT05480826)
- Testing
- study of the transmission of genetic variants
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fondation FondaMental
Autism Spectrum Disorder (ASD), Neurotypical
Autistic Eye Contact?
This research explored both breadth and depth of the experiences with eye contact in adults with and without ASD. A hermeneutic phenomenological multicenter design was used in which 15 adults with ASD and 15 adults without ASD…
- Trial name
- NCT06921876
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Autism Spectrum Disorder
Evaluation of Behavioural Psycho & Physiological Responses in People With ASD During a Blood Test in Routine Care Practice
The project is a prospective study designed to characterize behaviour and its psycho-physiological correlates of participants with ASD (children and adults) in comparison with subjects without ASD matched in age during blood test…
- Trial name
- AUTICOPP (NCT04638452)
- Testing
- Video & movements recording, Questionnaires
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
Autism Spectrum Disorder (ASD)
Investigation of the Genetic and Environmental Causes of Autism: a Multi-Center Study
The goal of this observational study is to investigate the genetic and epigenetic mechanisms that may contribute to the development of Autism Spectrum Disorder (ASD) in individuals of different age groups.
- Trial name
- ASD-Omics-TR (NCT06662591)
- Where
- 20 sites in Turkey (Türkiye)
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Research and Treatment Society of Genetic Disorders
Autism Spectrum Disorder, Temporomandibular Joint Disorders
Balance, TMJ, Social Adaptive Assessment in Individuals With Autism Spectrum Disorder
The aim of our study is to evaluate temporomandibular joint (TMJ), cervical posture, balance, dual-task performance, and social adaptation skills in individuals with autism.
- Conditions
- Autism Spectrum Disorder, Temporomandibular Joint Disorders, Postural; Defect
- Trial name
- NCT06721104
- Testing
- Dual Task, Functional Balance, Social Adaptation Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Autism Spectrum Disorders
Brain Imaging Study of Adults With Autism Spectrum Disorders
This research study investigates the effects of oxytocin and vasopressin on brain activity in adults with Autism Spectrum Disorders using functional magnetic resonance imaging (fMRI).
- Trial name
- NCT01093768
- Testing
- Oxytocin, Vasopressin
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Mental Disorders, Healthy Control
Psychiatric Multi-omics and Neuroimaging Project
This study focuses on the structure and function of the brain and gene expression in peripheral blood of patients with schizophrenia, to explore the interaction and influence between the three.
- Trial name
- PMNP (NCT06580860)
- Testing
- Antipsychotic drugs, antidepressants, mood stabilizers, and sleep aids
- Where
- China
- Volunteers
- 1,899 people, healthy volunteers welcome
- Sponsor
- mingjun Zhong
Autism Spectrum Disorder (ASD)
Internalized Symptoms in Adolescents With Autism Spectrum Disorder (ASD) and Typically Developing Adolescents : Gaining Insight Into Coping Strategies and the Psychological Processes Involved
Introduction: Adolescents with autism spectrum disorder (ASD) have more mental health problems than typically developping adolescents (without ASD).
- Trial name
- NCT07360223
- Testing
- Questionnaire and interview
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Autistic Disorder
Associative Memory in Adults With an Autism Spectrum Disorder
The objective of this multidisciplinary project is to explore the deficit of associative memory in ASD (Autistic Spectrum Disorder) that could result from abnormal brain connectivity.
- Trial name
- MEM-T2A (NCT02279680)
- Testing
- Electroencephalography, Neuropsychological assesments
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Eye-tracking, Autism Spectrum Disorder
Social COgnition Screening
Social cognition refers to the mental processes involved in social interactions, including social perception, motivation, communication, emotion recognition, and theory of mind.
- Conditions
- Eye-tracking, Autism Spectrum Disorder, Social Cognition, Diagnosis
- Trial name
- ECoS-A (NCT07377227)
- Testing
- eye-tracking, cognitive assessments
- Where
- France
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Autism Spectrum Disorder
Preliminary Efficacy of Occupational Therapy Integrating Horses on Self-regulation in Youth With Autism
The goal of this clinical trial is to learn about occupational therapy integrating horses for autistic youth. The main questions it aims to answer are: Does occupational therapy integrating horses improve self-regulation in…
- Trial name
- NCT05846932
- Testing
- OTEE HORS, OT Clinic
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Autism
Use of Functional Behavioral Assessments to Evaluate Stereotypy and Repetitive Behaviors in a Double-blind, Placebo Controlled Trials of Various Medications Used to Treat Children With Autism.
Autism, originally described by Kanner (1943), is among the most severe of neuropsychiatric disorders. It is a pervasive developmental disorder affecting social, communicative, and compulsive/repetitive behaviors characterized by…
- Trial name
- NCT00211770
- Testing
- Behavioral Assessment
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Autism Spectrum Disorder
CPI Training for Parents of Children With ASD
The purpose of this 24-week study is to determine whether the "Parent-based Crisis Prevention Institute (CPI) physical management training program" (i.e., P-CPI) is effective in increasing self-efficacy in parents of children…
- Trial name
- NCT03537261
- Testing
- Parent-based Crisis Prevention Institute (CPI) physical management training program (P-CPI)
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder
Radiomics of Autism Spectrum Disorder
Autism Spectrum Disorder (ASD) refers to a group of neurodevelopmental disorders including autism.Despite ongoing studies, the pathogenesis of ASD still remains unclear.The global prevalence of ASD was estimated at 1% in 2015.The…
- Trial name
- NCT05439954
- Where
- China
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Qingling Chen
Autism Spectrum Disorders
Improving Services and Outcomes for Children With Autism Spectrum Disorder (ASD)
Based on the need to characterize and improve early intervention services for minority and under-resourced children with ASD, this study translates a manualized and proven training model to examine its impact on the use of…
- Trial name
- NCT01800539
- Testing
- Provider Education Model (PEM)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.