Clinical trials: Pervasive Development Disorders
Autism Spectrum Disorder, Autistic Disorder
A Folinic Acid Intervention for Autism Spectrum Disorders
Researchers at Arkansas Children's Hospital Research Institute are conducting a study looking at the effects of Folinic Acid on language in Autism Spectrum Disorder and language impairment. The study has 3 phases.
- Conditions
- Autism Spectrum Disorder, Autistic Disorder, Autism, Asperger's Syndrome
- Trial name
- NCT01602016
- Testing
- Folinic Acid
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- University of Arkansas
Autism, Aggression
The Family VOICE Study
Family centered mental health treatment with children values and supports the role of parents in their child's recovery. However, medications are often the primary focus in community treatment, even in preschool age youth, with…
- Conditions
- Autism, Aggression, Bipolar Disorder, Psychotic Disorders
- Trial name
- NCT01804582
- Testing
- Family Navigator consultation
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- University of Maryland, Baltimore
Autism Spectrum Disorder
Exploring the Effectiveness of Dance as an Intervention to Promote Social-Emotional Health in Children With Autism Spectrum Disorder (ASD)
This study will explore the effectiveness of dance as an intervention to promote social-emotional health within children with ASD.
- Trial name
- ASD (NCT06295705)
- Testing
- Hip-Hop Dance
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Loma Linda University
Autism Spectrum Disorder
Evaluating the Impact of Telehealth-Based ASD Assessments and Supports on Child and Caregiver Outcomes
The overall goal of this study is to evaluate telehealth and internet-based approaches to meet accessibility challenges for families with concerns about ASD in their infants.
- Trial name
- NCT04881656
- Testing
- Help is in Your Hands
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of California, Davis
Autism Spectrum Disorder (ASD), Intellectual Disability
Verbal Intent and Gaze Cues on Action Prediction in ASD
A 2×2×3 mixed design (intent word × object type × group: TD, ASD, ID) was used. Age-matched children watched videos and judged which object a model would pick; their choices and eye movements were recorded.
- Trial name
- NCT07597694
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Autism Spectrum Disorder
Executive Function Intervention for Children With ASD Combining a Digital App and Parent Coaching
The purpose of this randomized controlled study is to develop and evaluate a digital cognitive control intervention that integrates a digital application-based child training program with an online parent coaching program for…
- Trial name
- NCT07376356
- Testing
- ChuckChuck Step, ChuckChuck Step (Shortened Parent Coaching)
- Volunteers
- 40 people
- Sponsor
- Korea University
Eating Disorders
Eating Disorders and Autism Spectrum Disorders
This is an observational study where patients with eating disorders (ED) are compared with healthy controls without eating disorder (HC) regarding eating disorders features and autism spectrum features.
- Trial name
- NCT04564170
- Where
- Spain
- Volunteers
- 135 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Autism Spectrum Disorders
Autism Spectrum Disorders (ASD) Characterization Study
The overarching aim of the study is to characterize children and adults with ASDs, and compare them with age-matched controls in relation to their functioning in family, academic, employment, and social spheres.
- Trial name
- NCT00801554
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Autistic Spectrum Disorder
Umbilical Cord Blood vs Personalized Treatments for Improving Autistic Disorder
The clinical study evaluates in an open-label, crossover design the comparative efficacy and safety of intranasal oxytocin and autologous umbilical cord blood for improving the functioning of children with autistic spectrum…
- Trial name
- NCT04007224
- Testing
- Intranasal oxytocin, Autologous umbilical cord blood
- Where
- 2 sites in Romania
- Volunteers
- 35 people
- Sponsor
- Fundatia Bio-Forum
Depression, Autism
Behavioral Activation for Treatment of Depression in Adolescents With Autism
In this study, the investigators will examine the feasibility, acceptability, and preliminary efficacy of a novel, behavior-based approach for treatment of depression symptoms in adolescents with autism spectrum disorder or ASD…
- Trial name
- BA-A (NCT05018169)
- Testing
- BA-A
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Virginia
Child Autism
Hyperbaric Oxygen Treatment in Autism Spectrum Disorders
Hyperbaric oxygen therapy (HBOT) is part of a multidisciplinary therapeutic management of infant autism including psychotherapy, drug treatment and other therapeutics (speech therapy, occupational therapy restrictive diet ...).
- Trial name
- NCT04472780
- Testing
- Hyperbaric oxygen Therapy HBOT
- Where
- Tunisia
- Volunteers
- 80 people
- Sponsor
- General Administration of Military Health, Tunisia
Fragile X Syndrome, FXS
A 2-Period Crossover Study of BPN14770 in Adults Males With Fragile X Syndrome
This is a single-center, randomized, double-blind, 2-period crossover study to explore the effects of BPN14770 on cognitive function and behavior in subjects with Fragile X Syndrome.
- Conditions
- Fragile X Syndrome, FXS, Fra(X) Syndrome
- Trial name
- NCT03569631
- Testing
- BPN14770
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Tetra Discovery Partners
Child Psychiatry
Evaluation of a Therapeutic Education Program for Pregnant Women with a First Child Diagnosed with an Autism Spectrum Disorder
Autism Spectrum Disorder (ASD) is a heterogeneous set of severe developmental abnormalities of the nervous system characterized by deficits affecting social interactions and verbal and non-verbal communication, as well as the…
- Trial name
- AUTMER (NCT05104112)
- Testing
- The M.E.R. program
- Where
- France
- Volunteers
- 132 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism Spectrum Disorder (ASD
EEG As a Genetic Selection Lever in Autism Spectrum Disorder
Autism Spectrum Disorder (ASD) is a growing public health concern, with genetic causes identified in about 20% of cases. While exome/genome sequencing is powerful, its cost and limited yield call for better patient selection.
- Trial name
- EAGLE (NCT07891065)
- Testing
- Collection of routine care data
- Where
- 2 sites in France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Autism, Cognition Disorder
The Effect of Donepezil (Aricept(Registered Trademark)) on REM Sleep in Children With Autism
This study will test whether donepezil (Aricept(Registered Trademark)), a drug that is approved by the Food and Drug Administration to treat Alzheimer's disease, can increase rapid eye movement (REM) sleep in children with autism…
- Trial name
- NCT00695136
- Testing
- Donepezil hydrochloride, Increase REM sleep percentage
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- National Institute of Mental Health (NIMH)
Autism Spectrum Disorder
Comparing Two Different Emotion Therapies for Autistic Youth and Young Adults
Too few clinicians are able and willing to help autistic patients. A recent review identified challenges to mental health service delivery in autism, including a lack of interventions designed for community implementation and…
- Trial name
- NCT06158581
- Testing
- The Emotion Awareness and Skills Enhancement Program, The Unified Protocol
- Where
- 2 sites in United States
- Volunteers
- 470 people
- Sponsor
- University of Pittsburgh
Schizophrenia, Autistic Disorder
Exploration of the Social Cognition in Adolescents With a Dissociative Disorder or Autism Spectrum
The schizophrenic disorders and pervasive developmental disorders are neurodevelopmental disorders distinct origin who share common challenges to engage and maintain social relationships and mutual disturbances of affective…
- Trial name
- NCT01805128
- Testing
- Facial recognition of emotions, understanding metaphors, Attribution of intentionality to others in social situations depending on the type of situation
- Where
- 3 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Autism Spectrum Disorder
Evaluating a Social and Communication Intervention for Preschoolers
The purpose of this study is to test the effectiveness of a school-based treatment aimed at increasing language and social skills in preschool-aged children with autism spectrum disorder (ASD).
- Trial name
- NCT01591707
- Testing
- ISC+PRT Intervention
- Where
- 3 sites in United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Autism Spectrum Disorder, Intellectual Disability
Expert Guiding Technology to Help Individuals With Developmental Challenges Build Life and Vocational Skills
Clinical trials will evaluate the efficacy of expert guiding technology to support instructors to better help individuals with developmental challenges due to ASD and ID learn life and vocational skills.
- Trial name
- NCT04518358
- Testing
- Use of Expert Guiding Technology (GAINS) to Improve Live and Vocational Skills for Individuals with Developmental Challenges
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- John T. Nosek
Autism, Autism Spectrum Disorder
Maternal Risk Factors for Autism Spectrum Disorders: A Case-Control Approach
New research suggests that about 1 in 8 children may be diagnosed with an autism spectrum disorder (ASD) in the United States. This could be due to several reasons which remain unknown.
- Conditions
- Autism, Autism Spectrum Disorder, Autistic Disorder, Pregnancy Related
- Trial name
- NCT05453708
- Testing
- Survey
- Where
- United States
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Walden University
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