Clinical trials: Pervasive Development Disorders
Autism
Adipose Derived Stem Cell Therapy for Autism
The intent of this clinical study is to answer the questions: 1. Is the proposed treatment safe 2. Is treatment effective in improving the disease pathology of patients with Autism.
- Trial name
- NCT01502488
- Testing
- Fat Harvesting and Stem Cell Injection
- Where
- United States
- Sponsor
- Ageless Regenerative Institute
Autism Spectrum Disorder (ASD)
Modified and Context-Focused Sports Intervention in Adolescents With Autism: Study Protocol
Adolescents with Autism Spectrum Disorder (ASD) typically engage less in physical activities than their typically developing peers, influenced by intrinsic and extrinsic factors.
- Trial name
- ASD (NCT06916988)
- Testing
- Sports Stars Brazil, context-centered therapy
- Where
- Brazil
- Volunteers
- 52 people
- Sponsor
- Federal University of Minas Gerais
Autism Spectrum Disorder
Effects of Probiotic Consumption in Children With Autism Spectrum Disorder (ASD)
The goal of this clinical trial is to determine the effects of Saccharomyces boulardii (Sb) consumption on Ecuadorian children with a diagnosis of autism spectrum disorder (ASD) and digestive symptoms.
- Trial name
- NCT06568588
- Testing
- S. boulardii CNCM (National Collection of Cultures of Microorganisms) I-745
- Where
- Ecuador
- Volunteers
- 66 people
- Sponsor
- Universidad San Francisco de Quito
Asperger's Disorder, Asperger Disorder
QAIAx - SGI/SI Smart Health Cities: Microcity Enclave Program (Quantum SI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360; USPTO EO 9424 Assignment ID: 2101042 / ARN: REEL/FRAME: 76481/0026 - OUSD-R&E, Department of War)
BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum SI/SGI Public Health Agency), known operationally as the "AI City Hall Project," represents a landmark intergovernmental research…
- Conditions
- Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism
- Trial name
- QAIAx (NCT07661823)
- Testing
- AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Veterans Recovery Network Inc.
PTEN, ASD
Natural History Study of Individuals With Autism and Germline Heterozygous PTEN Mutations
The purpose of this study is to determine cross-sectional and longitudinal medical, behavioral, and cognitive differences between PTEN ASD and other groups, as well as to identify cognitive, neural systems, and molecular…
- Conditions
- PTEN, ASD, Autism, Macrocephaly
- Trial name
- NCT02461446
- Where
- 5 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Children at Risk for ASD
Biomarkers of Developmental Trajectories and Treatment in Autism Spectrum Disorder (ASD)
The study will evaluate the efficacy of a novel intervention implemented in a classroom setting aimed at improving joint attention and joint engagement skills with infants who are at risk of developing an Autism Spectrum Disorder.
- Trial name
- BabyJ (NCT01874327)
- Testing
- Baby JASPER, Standard Baby Classroom
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of California, Los Angeles
Asperger Syndrome, High Functioning Autism
Portable Visual Guidance System Phase II
Abstract: In Phase I, we designed and tested a Portable Visual Guidance System (PVGS), which combines a PDA - for user guidance - and an Internet website - for linking the user to an educational support team.
- Trial name
- PVGS-II (NCT00848874)
- Testing
- PVGS
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Minna Levine, PhD
Autism
An Open Label Study of CM-AT for the Treatment of Children With Autism
This is a Phase III, open label extension study evaluating the continued safety and efficacy of CM-AT in pediatric patients with autism with all levels of fecal chymotrypsin.
- Trial name
- NCT02649959
- Testing
- CM-AT
- Where
- 31 sites in United States
- Volunteers
- 405 people
- Sponsor
- Curemark
Autism Spectrum Disorder
Reasoning Skills in Theory of Mind and Linguistic Tests in the Autistic Population
The purpose of this study is to investigate the correlation and the causality direction between mastering linguistic tests and second-order reasoning tasks in the autistic population.
- Trial name
- NCT02465086
- Testing
- Training of linguistic recursion
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Roskilde University
Autism Spectrum Disorder
Establish the Couple Intervention Program for Adults With Autism Spectrum Disorder
The development of adult intimate relationships and the transition into couplehood are part of most people's life cycles, but these transitions become very challenging for individuals diagnosed with autism spectrum disorder (ASD)…
- Trial name
- NCT05875376
- Testing
- Couple group therapy
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder
Communication Intervention for Toddlers With Autism
The goal of this study is to conduct an efficacy trial to determine whether an early communication intervention which blends two evidence-based interventions, Enhanced Milieu Teaching (EMT) and Joint Attention, Symbolic Play and…
- Trial name
- J-EMT (NCT02595697)
- Testing
- J-EMT for Toddlers with Autism
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Autism Spectrum Disorder, Microbiota
Gut-oral Axis Microbiome in Autism Spectrum Disorders
Autism Spectrum Disorder (ASD) is a neurodevelopment disorder characterized by impairment in social interaction, communication, and behavior, as well as sensory challenges.
- Trial name
- NCT05830591
- Testing
- Characterization of the microbiome in oral and fecal samples
- Where
- Italy
- Volunteers
- 86 people
- Sponsor
- IRCCS Burlo Garofolo
Autism Spectrum Disorders
Brain Imaging of Intranasal Oxytocin Treatment in Autism
This is a 4 part study: Phase 1a. -functional magnetic resonance imaging (fMRI) ( with oxytocin 24 IU vs. placebo = oxytocin 0 IU) - funded by grant #U54 HD079124-01, Phase 1b-eye-tracking(oxytocin 24 IU vs.
- Trial name
- NCT01945957
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of North Carolina, Chapel Hill
Autistic Disorder, Attention Deficit and Disruptive Behavior Disorders
Manville Moves: an Exercise Intervention for Behavioral Regulation Among Children With Behavioral Health Challenges
The purpose of this study is to examine whether an exergaming, aerobic physical education (PE) curriculum is acceptable and elicits improvements in behavioral self-regulation and classroom functioning among children with…
- Conditions
- Autistic Disorder, Attention Deficit and Disruptive Behavior Disorders, Anxiety Disorders, Mood Disorders
- Trial name
- MM (NCT02766101)
- Testing
- Aerobic Exergaming PE Curriculum, Standard PE
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Harvard School of Public Health (HSPH)
Autism Spectrum Disorder
Hyperthermia and the Amelioration of Autism Symptoms
The febrile hypothesis of Autism Spectrum Disorder (ASD) stems from the observation that clinical symptoms improve during fever.
- Trial name
- NCT01784744
- Testing
- Hydroworx Pool at 98 degrees Fahrenheit, Hydroworx Pool at 102 degrees Fahrenheit
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Montefiore Medical Center
Autism
Study of Pharmacokinetics, Safety, Efficacy, and Tolerability of Memantine in Children With Autism
The purpose of this study is to investigate the safety and efficacy of memantine extended release, as well as its extent of absorption in pediatric patients with autism.
- Trial name
- NCT00872898
- Testing
- Memantine - Extended Release (ER)
- Where
- 17 sites in United States
- Volunteers
- 124 people
- Sponsor
- Forest Laboratories
Autism
Show Me to Help Me
This cohort observation, randomized controlled trial is intended to provide data that icons and non-verbal communication improve communication and cooperation with children with Autism/communication delay and aid in the…
- Trial name
- NCT01311596
- Testing
- Icons
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Akron Children's Hospital
Autism Spectrum Disorder, Autistic Disorder
Sulforaphane for the Treatment of Young Men With Autism Spectrum Disorder
The aim of this randomized controlled trial is to determine if a nutritional supplement containing broccoli sprout and seed extracts, a rich source of sulforaphane, is effective in reducing core symptoms of autism spectrum…
- Conditions
- Autism Spectrum Disorder, Autistic Disorder, Neurodevelopmental Disorder, Childhood Developmental Disorders, Pervasive
- Trial name
- NCT02909959
- Testing
- Sulforaphane
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of North Carolina, Chapel Hill
Autism Spectrum Disorder, Wearable Devices
ASD Wearables Feasibility Study
The goal of this clinical study is to evaluate and compare the feasibility of wearable device use among pediatric participants with autism spectrum disorder (ASD) across four different wearable device form factors: a wristband…
- Trial name
- ASDW (NCT07504224)
- Testing
- 14-Day Device Monitoring
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Rady Pediatric Genomics & Systems Medicine Institute
Autism Spectrum Disorder, TMS
Transcranial Magnetic Stimulation (TMS) for Autism Spectrum Disorder
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by persistent difficulties in social communication and interaction, as well as restricted and repetitive patterns of behavior.
- Trial name
- TMS for ASD (NCT07910305)
- Testing
- Individualized Cerebellar-Targeted Repetitive Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Sir Run Run Shaw Hospital
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