Clinical trials: Pervasive Development Disorders
Autism Spectrum Disorder
Therapist and Parent Delivered Reciprocal Imitation Training for Young Children With Autism Spectrum Disorder
The purpose of this study is to examine whether adding a parent education component to an existing intervention (Reciprocal Imitation Training) results in improved outcomes for children with Autism Spectrum Disorder.
- Trial name
- ParentRIT (NCT03020927)
- Testing
- Reciprocal Imitation Training (Therapist-Delivered), Reciprocal Imitation Training (Therapist + Parent Delivered)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Ohio State University
Autism Spectrum Disorder
Early Intervention and Autism: Transformation From Research to Practice Through a Competency Based Model
This study evaluates the effect of a competency based model on program quality in Swedish preschools for Children with autism spectrum disorder (ASD).
- Trial name
- AUT-TID (NCT03634761)
- Testing
- Competency based model, Comprehensive program
- Where
- 2 sites in Sweden
- Volunteers
- 17 people
- Sponsor
- Stockholm University
Autism Spectrum Disorder
Telehealth Autism Assessment for Adults
The study aims to investigate the reliability and validity of an adapted Autism Spectrum Disorder assessment measure for use in a telehealth visit.
- Trial name
- NCT04766970
- Testing
- ADOS-2 Module 4, Adapted Telehealth ADOS-2 Module 4
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Autism Spectrum Disorder
Acceptability and Efficacy of a Culturally Adapted, Low-Frequency Parent-Mediated Early Start Denver Model (ESDM) Versus Standard Care in Young Children With Autism
Early intervention is effective in improving developmental outcomes of children on the autism spectrum. However, cultural and contextual factors may influence parental acceptability of treatment models, highlighting a need for…
- Trial name
- NCT07840586
- Testing
- Early Start Denver Model
- Where
- Singapore
- Volunteers
- 58 people
- Sponsor
- National University Hospital, Singapore
Autistic Disorders Spectrum
Neurostimulation for Cognitive Rehabilitation in Autistic Spectrum Disorders
This study is a clinical trial aims investigate the effects of neurostimulation in the treatment of children with mild ASD, specifically the action of tDCS on social cognition skills.
- Trial name
- NCT03947086
- Testing
- Transcranial Direct Current Stimulation (TDCS)- Active, Cognitive Training
- Where
- Brazil
- Volunteers
- 16 people
- Sponsor
- Federal University of Paraíba
Autism
Psychological and Quality of Life Impact of Brain in Hand
A prospective cohort mixed study using both qualitative and quantitative elements. The quantitative component will involve tracking outcomes at baseline and at twelve weeks, using Health of the Nation Outcome Scale for People…
- Trial name
- BraininHand (NCT05468541)
- Where
- United Kingdom
- Volunteers
- 101 people
- Sponsor
- Cornwall Partnership NHS Foundation Trust
Autism Spectrum Disorder, Anxiety
Effect of Cognitive Behavioural Therapy (CBT) for Children With Autistic Spectrum Disorders
Cognitive Behavioural Therapy is an effective intervention program for children with High-Functioning Autistic Spectrum Disorder to remediate anxiety issues.
- Trial name
- NCT01031511
- Testing
- Cognitive Behavioural Therapy, Social Recreational
- Where
- Singapore
- Volunteers
- 73 people
- Sponsor
- National Healthcare Group, Singapore
Sleep, Autism Spectrum Disorder
Transdiagnostic Sleep and Circadian Treatment for Autistic Adults
Sleep and circadian problems are associated with deleterious social, emotional, and cognitive outcomes, yet are modifiable. This prospective study will adapt and optimize an empirically supported behavioral intervention that…
- Conditions
- Sleep, Autism Spectrum Disorder, Transdiagnostic
- Trial name
- NCT07461844
- Testing
- Transdiagnostic Intervention for Sleep and Circadian Dysfunction
- Volunteers
- 24 people
- Sponsor
- Milton S. Hershey Medical Center
ASD, Scoliosis Idiopathic Adolescent
Quality of Life, Psychosocial Burden, and Structural-functional Status in Adults With Spinal Deformity.
This study examines which factors influence quality of life in adults with a spinal deformity. It looks at imaging findings together with pain, daily functioning, psychosocial factors, and frailty to support more person-centred…
- Conditions
- ASD, Scoliosis Idiopathic Adolescent, Scoliosis Idiopathic Adolescent Treatment
- Trial name
- ASD-QoL (NCT07749534)
- Testing
- first corrective surgery, Reoperation
- Where
- Belgium
- Volunteers
- 320 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Autism Spectrum Disorder
Emotion Awareness and Skills Enhancement Program
This project will address impaired emotion regulation in adolescents with ASD (autism spectrum disorder). There are no evidence-based interventions to improve emotion regulation (ER) in this population, yet poor emotion…
- Trial name
- EASE (NCT03432832)
- Testing
- EASE, Supportive Therapy
- Where
- 2 sites in United States
- Volunteers
- 113 people
- Sponsor
- University of Pittsburgh
Autistic Disorders Spectrum, Sexual Behavior
Sexaffectivity in Autistic Spectrum Disorder
The WHO defines sexual health as a state of physical, emotional, mental and social well-being, related to sexuality, not only the absence of illness, dysfunction or disability.
- Conditions
- Autistic Disorders Spectrum, Sexual Behavior, Adolescent Development, Sexual Inadequacy
- Trial name
- NCT03625609
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Parc Taulí Hospital Universitari
Autism, Food Allergies
Treatment of Autistic Children Using NAET Procedures
1. Purpose of this study is to determine whether NAET procedures are effective in the treatment of children with allergy-related autism spectrum disorders in restoring their verbal and nonverbal communication. 2.
- Trial name
- NCT00277407
- Testing
- NAET with acupressure and/or chiropractic procedures
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Nambudripad's Allergy Research Foundation
Autism Spectrum Disorder
The Effect of Exergame-Supported Training on Reaction Time and Agility
This study looks at whether a type of exercise video game, called an exergame, can help adolescent boys with autism spectrum disorder (ASD) who play table tennis react faster and move more quickly (agility) during play.
- Trial name
- NCT07765277
- Testing
- Exergame Training
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Princess Nourah Bint Abdulrahman University
Autism Spectrum Disorder (ASD
Combination of Supplements for Treating Autistic Spectrum Disorder
A pilot study to compare the efficacy of a combination of apitherapy supplements versus placebo in children with autistic spectrum disorder.
- Trial name
- APITSA (NCT06756711)
- Testing
- A combination of apitherapy and plant extracts
- Where
- 2 sites in Romania
- Volunteers
- 40 people
- Sponsor
- Fundatia Bio-Forum
Autism Spectrum Disorder, High-functioning Autism
Neuralized1 and RGS14 Genes
Autism is a broad spectrum neurodevelopmental disease. Some individuals with ADS by high cognitive functions are diagnosed with High Functioning Autism (HFA).
- Conditions
- Autism Spectrum Disorder, High-functioning Autism, Healthy
- Trial name
- NCT04865198
- Testing
- Neurl1 gene expression, RGS14 gene expression
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Autism Spectrum Disorder, Autism
Effects of Animal-assisted Therapy on the Physical Function and Communication of Adults With Autism
The aim is to evaluate the effects of a dog-assisted therapy program on physical function and communication in a sample comprised of 24 adults with autism spectrum disorder.
- Trial name
- NCT04859998
- Testing
- dog-assisted therapy
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- Daniel Collado-Mateo
Autism Spectrum Disorder, Parent-Child Relations
Pilot Testing of a Mobile Phone App-based Intervention for Parents of Children With Autism Spectrum Disorder (ASD)
The objective of this study is to conduct a pilot randomised controlled trial (RCT) evaluating the feasibility, acceptability, and preliminary efficacy of a 6-week mobile app-based intervention in empowering and supporting…
- Trial name
- NCT05927207
- Testing
- TRIP
- Where
- Hong Kong
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
ASD
Differences in N-CAD Concentration and Brain Function Between Children With ASD and TD
The incidence of autism spectrum disorders is increasing, about 1 / 36. Neural cadherin (NCAD) is closely related to synaptic structure and function.
- Trial name
- NCT07400484
- Where
- China
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Chen Li
Autism Spectrum Disorders
A Study of a Developmental,Individual-Difference,Relationship-Bases/Floortime Intervention for Children With Autistic
Thirty eight autistic spectrum disorder children age 2-6 years recruited into the study. The new treatment intervention is based on the DIR Model. Parents will be coached at the start and then every 3-4 months for 1 year.
- Trial name
- DIR (NCT00954213)
- Testing
- DIR/Floortime parent intervention
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Parent-Child Relations, Meals
Parent-Mediated Intervention for Families With Children With Autism and Feeding Challenges
The goal is to pilot a parent-mediated intervention for feeding challenges in children with autism building on recent research and current successful models already being used.
- Conditions
- Parent-Child Relations, Meals, Autism Spectrum Disorder
- Trial name
- NCT03071120
- Testing
- Parent-Mediated Intervention
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
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