Clinical trials: Pervasive Developmental Disorders
Autism Spectrum Disorders
Social Interactions: Ocular Explorations and Pupillometry in Autism
The primary objective of this work will first to characterize in typical childhood, visual exploratory behavior and pupillary response associated with salience of human social stimuli (faces and body movements), and then to…
- Trial name
- ISEOP (NCT01647295)
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Autism
Assessment Of Spinal Posture, Balance And Ankle Muscle Shortness İn Children With Autism
The aim of this study is to evaluate spinal posture, mobility, balance and ankle muscle shortness in children with autism. The study will feature two groups, First group will consist of children with autism Second group will…
- Trial name
- NCT06995716
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Physical Activity, Motor Skills Development
Feasibility and Acceptability of a Co-produced Intervention to Improve Physical Activity and Motor Competence Amongst Children With Intellectual Disabilities and/or Autism Spectrum Disorder: Movement Matters
The goal of this observational study is to find out whether an intervention designed to improve physical activity levels and movement skills is practical and acceptable for children aged 7-11 years with intellectual disabilities…
- Trial name
- MM (NCT07456514)
- Testing
- Movement Matters
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Autism Spectrum Disorder
Social Motivation Intervention for Children With Autism Spectrum Disorder: Improving Peer Initiation
The purpose of this study is to investigate whether a social initiation motivation intervention (SIMI) focused on training children with ASD to initiate to peers during structured play activities will result in more frequent…
- Trial name
- NCT02360449
- Testing
- Social Initiation Motivation Intervention
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Stanford University
Autism Spectrum Disorder
The Effect of Hepatic Impairment on the Pharmacokinetics of Balovaptan
This is a multi-center, non-randomized, open-label, parallel group, multiple-dose study to assess the pharmacokinetic, safety, and tolerability of balovaptan in male and female subjects with moderate hepatic impairment compared…
- Trial name
- NCT03912350
- Testing
- Balovaptan
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Autism Spectrum Disorder
Neuro Strengths-Based Approach to Autism
The Neuro-Strength-Based Approach to Autism (NSBAA) attempts to translate what research has discovered about the autistic brain into terms that autistics, and those involved with autistics, can understand.
- Trial name
- NSBAA (NCT05499910)
- Testing
- NSBAA
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Baio Enterprises
Autism Spectrum Disorders
Emotion Regulation in Preschoolers With Autism and Their Parents
In the proposed study, the investigators would like to investigate the emotion regulation (ER) strategies children with Autism Spectrum Disorders (ASD) demonstrate, and the influence parents have on their children's ER.
- Trial name
- NCT01643720
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Autism
Neurophysiological Molecular and Developmental Analysis of the Glutamate Synapse in Autism
Neurophysiological, Molecular and Developmental Analysis of the glutamate synapse in Autism
- Trial name
- NMDA-Autism (NCT01770548)
- Testing
- analysis of the glutamate synapse in autism, DNA collection, Auditory evoked potentials
- Where
- 4 sites in France
- Volunteers
- 497 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Autism Spectrum Disorder, Fragile X Syndrome
Speech-in-noise Perception in Autism and Fragile X
The goal of this study is to identify which brain regions are active during speech-in-noise perception, as well as how those regions interact.
- Trial name
- NCT06088589
- Testing
- Mismatch negativity
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autism, Developmental Delay
Developmental Delay in Children Exposed During Pregnancy to Either Lamotrigine,Sodium Valproate, or Carbamazepine
This study is investigating the neurodevelopmental effects of prenatal exposure to lamotrigine (LTG), sodium valproate (VPA), or carbamazepine (CBZ) monotherapies. The hypotheses to be tested include: 1.
- Conditions
- Autism, Developmental Delay, Birth Defects
- Trial name
- NCT01097720
- Where
- United States
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Anxiety, Autism Spectrum Disorder
Aromatherapy for Anxiety Among Children With Autism Spectrum Disorder
This study evaluated the use of bergamot aromatherapy in the treatment of anxiety in a medical office setting among children who are diagnosed with an autism spectrum disorder. H
- Trial name
- NCT03818490
- Testing
- Bergamot Aromatherapy
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Nutraceuticals Research Institute
Autism Spectrum Disorder
Tool for Evaluating the Effectiveness of the DENVER Protocol
Early remediation of the communicative and social difficulties of children with autism spectrum disorders (ASD) is central. However, from the age of 6-8 months, children with ASD show a lack of attention to social stimuli such as…
- Trial name
- FACECOM (NCT06253793)
- Where
- 3 sites in France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Anxiety Acute, Stress
Drumming Groups for Parents of Autistic Children
This project aims to encourage a sense of belonging, community, and emotional support for parents of autistic children through a group drumming (music therapy) intervention.
- Conditions
- Anxiety Acute, Stress, Depression and Quality of Life, Stress in Parents of Autistic Children
- Trial name
- DG_PAC (NCT07375043)
- Testing
- Group Drumming
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Autism Spectrum Disorder
Biofeedback Intervention in Adolescents With Autism Spectrum Disorder
This study consists of two phases, a cross-sectional and a interventional. The cross-sectional phase will provide more insight into the differences in the autonomic functioning between adolescents with autism spectrum disorder…
- Trial name
- NCT04628715
- Testing
- RSA biofeedback
- Where
- Belgium
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Autistic Disorder
Diffusion Tensor Imaging in Autism
Using a new and more detailed approach to diffusion tensor imaging (DTI) recently developed in our lab, the investigators hope to learn more about irregularities in the brain that are related to autism.
- Trial name
- NCT00382382
- Testing
- diffusion tensor imaging (DTI)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Autism Spectrum Disorder
Emotional Proactive Brain Study in Adults With Autism Spectrum Condition
This project aims: to study behavioral and cerebral activity specificity (latency and amplitude of evoked potentials, time frequency maps and cerebral connectivity) in predictive process (top-down regulation) during visual…
- Trial name
- PREDEMAUT (NCT04069676)
- Testing
- EEG
- Where
- France
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Autism Spectrum Disorder
Early Screening of Autism Spectrum Disorder in General and Pediatric Practices
Early screening for Autism Spectrum Disorder has been validated using different screening tools, in particular M-CHAT-R and ITC in different countries. Unfortunaltely, in France, they are not often used.
- Trial name
- KitCAT (NCT04274127)
- Testing
- early detection kit composed of 2 questionnaires (M-CHAT-R + CSBS-ITC)
- Where
- France
- Volunteers
- 1,211 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Autism Spectrum Disorder
Reliability Study Using Electrodermal Activity to Measure Sensory Processing in Children With and Without Autism Spectrum Disorder
The purpose of this study is tTho establish test-retest reliability of electrodermal markers used to quantify physiologic response to sensation using the Sensory Challenge Protocol in children with and without Autism Spectrum…
- Trial name
- NCT02646696
- Testing
- Sensory Challenge Protocol
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Barpak Geriatric Health Services, Inc. d/b/a Barpak Occupational Therapy
Autism Spectrum Disorders, Mood Disorders
Multidimensional Measurement of Psychopharmacological Treatment Response
The study examines actigraphic, observational, psychometric and associated repeated measurements obtained prior to and during psychopharmacological treatment.
- Conditions
- Autism Spectrum Disorders, Mood Disorders, Sleep Disorders, Attention Deficit Disorders
- Trial name
- NCT01184235
- Testing
- Pharmacological Intervention
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Child Psychopharmacology Institute
Autism Spectrum Disorders, Non-verbal Learning Disorder
Comparison of ABLLS-R and Portage Guide in the Development of Receptive Language Skills Autism Spectrum Disorder.
Language is the system someone uses to communicate with another person. This covers the origins and construction of words, their definitions, and the use of language in various contexts.
- Trial name
- NCT06292520
- Testing
- Portage Guide Protocol, ABLLS-R protocol
- Where
- Pakistan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Riphah International University