Clinical trials: Pesticide Exposures
Pesticide Safety
Reducing Farmworkers Exposure to Agricultural Chemicals
The goal of this project is to develop and test the effectiveness of a Lay Health Advisor program to teach migrant and seasonal farmworkers about pesticide safety in their homes.
- Trial name
- NCT00298649
- Testing
- Lay Health Advisor
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Infant, Newborn
MecoExpo Study Protocol
The MecoExpo project seeks to evaluate the in utero exposure of newborns in the Picardie region to commonly used pesticides. These pesticides were selected in a pilot study (the Mecopic study) on the basis of their toxicity…
- Trial name
- MecoExpo (NCT02899819)
- Testing
- meconium
- Where
- 11 sites in France
- Volunteers
- 1,020 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Infant, Low Birth Weight, Infant, Premature, Diseases
Farm Work & Preterm Low Birthweight Among Hispanic Women
The most persistent and intractable cause of infant and child mortality and morbidity in the US remains preterm and low birthweight deliveries.
- Trial name
- NCT00015613
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Toxicology
Temporal Variation of the Exposure to Pesticides in the Employees of the Limoges University Hospital
In a sample of 300 employees of the Limoges University Hospital, it is proposed to explore the intraindividual and interindividual variability of urinary concentrations of glyphosate and 320 other pesticides.
- Trial name
- VESTAL (NCT06045234)
- Testing
- Urine sampling
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Lymphoma Diffuse Large B-cell
Occupational Exposure to Pesticides in the Prognosis of Lymphomas
The link between the products of synthetic chemistry and cancer is at the heart of much research. Recent work has identified the use of plant protection agents by farmers as a risk factor for developing non-Hodgkin lymphoma…
- Trial name
- ProLyPhy (NCT02898870)
- Where
- France
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Prostate Cancer, Pesticide Exposures
Agriculture Health Study
The "Agricultural Health Study" (AHS) is a collaborative effort between the National Cancer Institute and the National Institute of Environmental Health Sciences. The U.S.
- Conditions
- Prostate Cancer, Pesticide Exposures, Lymphoma, Multiple Myeloma
- Trial name
- NCT00352924
- Where
- United States
- Volunteers
- 89,655 people
- Sponsor
- National Cancer Institute (NCI)
Organophosphate Poisoning
Farming, Personal Protective Equipment, Nepal
According to the World Health Organization pesticide poisoning is a major health problem due to the millions of cases annually occurring worldwide.
- Trial name
- NCT02137317
- Testing
- LAPPE (locally adapted personal protective equipment)
- Where
- Nepal
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Pesticide Exposure
Organochlorine Pesticide Exposure in Residents Near Lake Apopka
In the Lake Apopka, Florida area for over 50 years starting in the 1940s, organochlorine pesticides (OCPs) including 4,4'-dichlorodiphenyltrichloroethane (DDT), dieldrin, chlordane, toxaphene and more recently methoxychlor were…
- Trial name
- NCT02530814
- Testing
- Blood Collection
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Florida
Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype
Impact of Pesticide Exposure on Survival and Tumor Aggressiveness in Patients With Glioblastoma: A Prospective Clinical Study
This prospective, interventional, monocentric study will aim at investigating the relationship between pesticide exposure and the treatment response of patients with GBM.
- Trial name
- EXPOGLIO (NCT07788430)
- Testing
- Biological sample collection, Self-reported questionnaire
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Institut Claudius Regaud
Pesticide Exposure
Pesticide Exposure and Health Status in North Carolina African American Male Farmers and Farm Workers
We propose to conduct a study to increase our understanding of farming practices and of the potential for previous exposure to DDT in North Carolina African American male agricultural workers, a group especially likely to have…
- Trial name
- NCT00341965
- Where
- United States
- Volunteers
- 275 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Non Communicable Diseases, Microbiome
Mapping the Health Status of the Population of French Polynesia: the MATAEA Project
This is a cross-sectional study carried out on a sample of the adult population aged 18 to 69, distributed over the five archipelagos of French Polynesia.
- Conditions
- Non Communicable Diseases, Microbiome, Communicable Diseases, Pesticide Exposure
- Trial name
- MATAEA (NCT06133400)
- Testing
- Questionnaire, Physical measurements, Biological samples
- Where
- French Polynesia
- Volunteers
- 1,942 people, healthy volunteers welcome
- Sponsor
- Institut Louis Malardé
Congenital Malformation
Pregnancy Environment and Newborn Malformations
Congenital malformations rate is about 3% in France. There are already 5 registries in France, covering about 16% of French births: Paris Registry, (about 38 000 births /year), Alsace Registry, (about 23 000 births/year)…
- Trial name
- PENEW (NCT01613638)
- Testing
- meconium samples + maternal self-questionnaire
- Where
- 11 sites in France
- Volunteers
- 1,657 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Multiple Myeloma
Multiple Myeloma and Environmental Exposure to Pesticides in the French West Indies: A Population Based Case-control Study.
Multiple myeloma (MM) is a malignancy of plasma cells engaging in monoclonal immunoglobulin production. A strong presumption was established between exposure to pesticides and the risk of MM.
- Trial name
- MYELODOM (NCT04260490)
- Where
- 2 sites in Guadeloupe, Martinique
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
Diet, Food, and Nutrition, Exercise
The NutriNet-Santé Study
The NutriNet-Santé study was set up to investigate nutrition and health relationships. Specifically, it was the first web-based cohort worldwide on such a large scale (n=171 000 as of 2021) focused on the complex link between…
- Conditions
- Diet, Food, and Nutrition, Exercise, Diseases Category, Cohort Studies
- Trial name
- NCT03335644
- Where
- France
- Volunteers
- 170,000 people, healthy volunteers welcome
- Sponsor
- University of Paris 13
Pesticide, Breast Milk
Impact of Exposure to Persistent Organic Pollutants During Pregnancy on the Composition of Breast Milk and Consequences on the Newborn
Epidemiological studies link early exposure to persistent organic pollutants (POPs) with health consequences in the newborn. Experimental studies have shown the impact of POPs on the gut microbiota.
- Conditions
- Pesticide, Breast Milk, Pollution; Exposure, Meconium
- Trial name
- PESTIMICOBLAIT (NCT03969459)
- Testing
- breast milk collection, meconium collection, newborn feces collection
- Where
- France
- Volunteers
- 88 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Poisoning
Pesticide Exposure Pathways for Farmworker Children
This project is aimed at better understanding how children living in agricultural environments are exposed to pesticides, and how such exposures can be prevented or reduced.
- Trial name
- NCT00013754
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Pesticide Exposure, Food Safety
COM-B Model-based Behavioral Intervention on Safe Pesticide Use and Food Safety Practice Among Farmers
This study evaluates the effectiveness of a COM-B-based behavioral intervention to improve safe pesticide use and food safety practices among smallholder farmers in Ethiopia, using a cluster-randomized controlled trial design.
- Trial name
- NCT07507994
- Testing
- COM-B-Based Behavioral Intervention, Active Comparator: Routine agricultural extension services
- Volunteers
- 572 people, healthy volunteers welcome
- Sponsor
- Bahir Dar University
Peripheral Neuropathy
Neurotoxic Health Hazards of Long-Term Low-Level Exposure to Organophosphate (OP) Compounds in in Hula Valley
During 1987-1991, WHO supported studies of exposures and short term neurobehavioral effects in a cohort (n=200) with occupational and community exposures to pesticide drift containing organophosphates from orchards and cotton…
- Trial name
- NCT00671866
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Multiple Myeloma, Leukemia
Specimen Collection for Agricultural Health Study Cohort Pesticide Exposure Study
Background: Multiple myeloma (MM), a type of cancer that affects the white blood cells, is often preceded by a precancerous disorder known as monoclonal gammopathy of undetermined significance (MGUS).
- Conditions
- Multiple Myeloma, Leukemia, MGUS, Monoclonal B-Cell Lymphocytosis
- Trial name
- NCT01139476
- Where
- United States
- Volunteers
- 1,892 people
- Sponsor
- National Cancer Institute (NCI)
Pregnancy Related, Pregnancy Complications
The Heartland Study
The Heartland Study is a prospective, observational study that will enroll up to 2,600 pregnant participants across the Heartland States in the U.S..
- Conditions
- Pregnancy Related, Pregnancy Complications, Birth Defect, Gestational Age and Weight Conditions
- Trial name
- NCT05492708
- Where
- 4 sites in United States
- Volunteers
- 2,600 people, healthy volunteers welcome
- Sponsor
- Heartland Health Research Alliance