Clinical trials: Phacoemulsification
Cataract
Postoperative Total Wavefront Pattern Between Two Types of Intraocular Lenses Implanted in Cataract Surgery
With the advancement of cataract eye surgery and wavefront sensors, the previously unquantifiable refractive measurements have been identified and the high order aberrations have shown their effect on high resolution imaging.
- Trial name
- NCT04701255
- Testing
- phacoemulsification with intraocular lens implantation, ocular aberrometer assesment
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Glaucoma, Open-Angle, Glaucoma Secondary
Assessment of Effectiveness Ex-Press Surgery Modification
The purpose of the study is to compare the effectiveness and safety profile of ExPress implantation versus partial deep sclerectomy combined with ExPress implantation with simultaneously phacoemulsification.
- Conditions
- Glaucoma, Open-Angle, Glaucoma Secondary, Glaucoma, Primary Open Angle
- Trial name
- NCT03800589
- Testing
- phacoemulsification with implantation of the Ex-Press, deep sclerectomy, phacoemulsification, ExPress implantation
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Military Institute od Medicine National Research Institute
Post Operative Anterior Chamber Inflammation (Flare)
A Comparison of Post Phacoemulsification Aqueous Flare in Patients Using Ketorolac 0.45% 2 Times Daily (BID) and Bromfenac 0.09% 2 Times Daily (BID)
Approximately 50 patients undergoing cataract surgery will be randomized in an even allocation (1:1) into two treatment groups, either ketorolac 0.45% BID or bromfenac 0.09% BID.
- Trial name
- NCT01023724
- Testing
- Ketorolac Tromethamine 0.45%, Bromfenac 0.09%
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bucci Laser Vision Institute
Cystoid Macular Edema, Cataract
Anti-inflammatory Efficacy for Prophylaxis of Cystoid Macular Edema (CME) After Phacoemulsification
To compare the anti-inflammatory efficacy of ketorolac of tromethamine 0.4% and nepafenac 0.1% eye drops for prophylaxis of cystoid macular edema (CME) after small-incision cataract extraction.
- Trial name
- NCT02084576
- Testing
- Nepafenac, Ketorolac
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital Oftalmologico de Brasilia
Cataract; Surgery; Phacoemulsification; Biometry; Intraocular Lens Power
Comparison of SRK-T With Kane Formula for Prediction of Refractive Outcome After Phacoemulsification
Cataract is a leading cause of blindness in the world. Cataract surgery is one of the most commonly performed ocular procedures.
- Trial name
- NCT05564455
- Testing
- Biometry with Kane formula, Biometry with SRK-T formula
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Cataract
Parameters of 2 Phaco Tips Designs in Torsional Phacoemulsification
To compare the efficiency of surgical procedures using 2 phaco tip designs in torsional phacoemulsification using the bevel-down technique.
- Trial name
- NCT02089698
- Testing
- Mini-flared, Reversed tip
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Oftalmologico de Brasilia
Oral Anxiolytic, Phacoemulsification
Anxiety and Surgery Satisfaction for Cataract Patient With Different State Anxiety
This study aims to explore the effects of anxiety traits on pain, anxiety, and anesthesia satisfaction in patients undergoing cataract surgery under topical anesthesia.
- Conditions
- Oral Anxiolytic, Phacoemulsification, Cataract Surgery, Satisfaction Survey
- Trial name
- NCT06826417
- Testing
- Xanax
- Where
- Taiwan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cataracts
Aqueous Absorption and Pharmacokinetics of Besivance Versus VIGAMOX in Patients Undergoing Phacoemulsification
The purpose of this study is to compare drug concentrations in aqueous humor following ocular instillation of Besivance and VIGAMOX in subjects undergoing cataract surgery.
- Trial name
- NCT01296191
- Testing
- Moxifloxacin, besifloxacin
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Frank A. Bucci, Jr., M.D.
Cataract Surgery
A Prospective Multicenter Study To Assess The Clinical Outcomes Of Current Phacoemulsification Approach To Cataract Extraction Versus The Micor System Device
The purpose of this research study is to evaluate the clinical outcomes of current phacoemulsification approaches to cataract extraction involving high-frequency thermogenic energy versus the use of the MICOR System device using…
- Trial name
- NCT05729477
- Testing
- miCOR System, Phaco Subject Cohort
- Where
- 6 sites in United States
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Cystoid Macular Edema Following Cataract Surgery
CME With Different Fluidic Parameters
Understanding and modulating fluid parameters is an important, but often overlooked aspect of phacoemulsification. In a previous study we compared the impact of using high fluid parameters versus low fluidic parameters on…
- Trial name
- NCT01385852
- Testing
- microcoaxial phacoemulsification
- Where
- India
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Iladevi Cataract and IOL Research Center
Lenses, Intraocular
Visual Acuity After Using A New Monofocal Intraocular Lens Compared To Standard Monofocal Lens
This is a prospective comparative interventional clinical study, that took place from January 2021 to November 2021. Twenty patients (20) were enrolled in this study 10 patients in each group.
- Trial name
- NCT05430295
- Testing
- phacoemulsification, monofocal intraocular lens implantation
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Diabetes Mellitus
Corneal Changes in Diabetics After Phacoemulsification
This study aims to assess the corneal damage after phacoemulsification and to assess the factors causing it in diabetics in comparison with non-diabetics.
- Trial name
- NCT02548273
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Jawaharlal Institute of Postgraduate Medical Education & Research
Refractive Errors, Cataract
Refractive Outcomes After Cataract Surgery in Eyes With Pseudoexfoliation Syndrome
To evaluate the refractive outcomes of cataract surgery in PEX syndrome and determine which of the commonly used IOL formulas (SRK/T, Barrett Universal II and Hill-RBF) is the best in predicting postoperative refractive outcomes…
- Trial name
- NCT04783909
- Testing
- Phacoemulsification cataract surgery
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Lublin
Astigamtism
Prospective Comparative Study of Refractive Outcome of STAAR and Alcon Toric Intraocular Lenses
Several methods have been developed to address and reduce preexisting astigmatism. The refractive results associated with the use of toric IOLs are likely to be more predictable.
- Trial name
- NCT01121861
- Testing
- Phacoemulsification with implantation of toric IOL
- Where
- Singapore
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Dry Eye
Dryness Difference Between Before and After Phacoemulsification
The aim of this study is to compare tear film and tear film secretion before and after phacoemulsificaton cataract surgery
- Trial name
- NCT06513000
- Testing
- Dry eye diagnostic system
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Posterior Synechiae of Iris
Mydriatic Drops After Combined Surgery
The study goal is to evaluate the influence of mydriatic drops on the development of posterior synechia after combined cataract and vitrectomy surgery.
- Trial name
- NCT05614622
- Testing
- Cyclopentolate Hydrochloride 1.0% eye drops
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Cataract
Outcomes of Phacoemulsification With Torsional Ultrasound
To determine the differences in intra-operative complications, surgical duration, fluid usage, corneal thickness and endothelium cell density in eyes undergoing microcoaxial phacoemulsification (MCP) either with Torsional or…
- Trial name
- NCT01010490
- Testing
- Torsional ultrasound (INFINITI, Alcon, USA), Longitudinal U/S (Infiniti system, Alcon, USA), Longitudinal U/S (LEGACY 20000, Alcon, USA)
- Where
- India
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Iladevi Cataract and IOL Research Center
Cataract Unilateral Pending Extraction, Anesthesia
Comparing Ropivacaine and Bupivacaine in DTFNB Anesthesia in Patients Undergoing Phacoemulsification
Deep topical fornix nerve block anaesthesia is now a known form of nerve block for cataract surgeries by phacoemulsification. In this study the investigators intend to compare ropivacaine and bupivacaine in various parameters…
- Trial name
- DTFNB (NCT02925832)
- Testing
- Deep Topical Fornix Nerve block anesthesia, Ropivacaine, Bupivacaine
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Government Medical College, Haldwani
Cataract
A Randomized Controlled Study of Phacoemulsification by the Enlarged Internal Incision and the Regular 2.2mm Incision
Objective and Principle: To evaluate whether enlarging the incision can reduce corneal complications associated with phacoemulsification with regular 2.2 mm incision.
- Trial name
- NCT03976791
- Testing
- enlarged internal incision, regular 2.2mm incision
- Where
- China
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Cataract, Shallow Anterior Chamber
Assessment Of Anterior Chamber Configuration Changes After Phacoemulsification
To investigate changes in anterior chamber angle configuration after phacoemulsification and intraocular lens (IOL) implantation with Swept-Source Optical Coherence Tomography (SS-OCT).
- Conditions
- Cataract, Shallow Anterior Chamber, Narrow Angle
- Trial name
- AOACCCAP (NCT02238002)
- Testing
- cataract surgery
- Where
- China
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Zheng Qian