Clinical trials: Phacoemulsification
Corneal Endothelial Cell Loss, Pseudoexfoliation Syndrome
Corneal Endothelium After Phacoemulsification in Pseudo Exfoliation Syndrome
To study corneal endothelial cells changes after phacoemulsification in patients with senile cataract and pseudoexfoliation syndrome (PEX) compared with control patients with senile cataract using specular microscope.
- Trial name
- NCT05447130
- Testing
- phacoemulsification
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Minia University
Cataracts
Comparison of Tetracaine 0.5% and Lidocaine 2% Jelly for Topical Phacoemulsification Cataract Surgery
The purpose of this study is to determine if there is a difference on the penetration of betadine 5% when using lidocaine 2% jelly versus topical tetracaine 0.5% in topical cataract surgery.
- Trial name
- NCT00827073
- Testing
- tetracaine 0.5%, Lidocaine 2% Jelly
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hermann Eye Center
Cataract Surgery
Comparison of Two Phacoemulsification Systems in Cataract Surgery (UNITY VCS vs. Centurion)
This prospective, randomized, contralateral (crossover) study compares the ultrasound efficiency and early postoperative outcomes (Day 1 and Day 7) of two phacoemulsification platforms - the UNITY® VCS system with 4D Phaco and…
- Trial name
- COMPASS (NCT07756385)
- Testing
- UNITY VCS SYSTEM ®, CENTURION VISION SYSTEM ®
- Where
- Croatia
- Volunteers
- 30 people
- Sponsor
- University Hospital Sveti Duh
Cataract
Physiologic Phacofluidics: Ghost Protocol
The goal of this clinical trial is to investigate the early post-operative benefits of performing phacoemulsification at physiologic intraocular pressures.
- Trial name
- NCT06904404
- Testing
- Cataract surgery at high IOP, Cataract surgery at low IOP
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Wolfe Eye Clinic
Refractive Errors, Cataract
Refractive Outcomes After Cataract Surgery in Eyes With Pseudoexfoliation Syndrome
To evaluate the refractive outcomes of cataract surgery in PEX syndrome and determine which of the commonly used IOL formulas (SRK/T, Barrett Universal II and Hill-RBF) is the best in predicting postoperative refractive outcomes…
- Trial name
- NCT04783909
- Testing
- Phacoemulsification cataract surgery
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Lublin
Cataract Surgery, Shallow Anterior Chamber
FLACS vs Phaco in Shallow Anterior Chamber
Phacoemulsification in eyes with a shallow anterior chamber (ACD < 2.2mm) presents with problems of safe access to the cataract and increased vulnerability of the endothelium and a higher tendency of complications such as…
- Conditions
- Cataract Surgery, Shallow Anterior Chamber, Phacoemulsification
- Trial name
- NCT03587909
- Testing
- Phacoemulsification Cataract SUrgery, Femtosecond Cataract Surgery
- Where
- India
- Volunteers
- 91 people
- Sponsor
- Iladevi Cataract and IOL Research Center
Cataract
A Cataract Surgery Clinical Trial
The purpose of the study is to compare the efficiency and safety of UNITY™ Vitreoretinal Cataract System (UNITY VCS) to CENTURION® Vision System with Active Sentry (CAS) in adult subjects with grade 2 or greater nuclear sclerotic…
- Trial name
- NCT07044674
- Testing
- UNITY Vitreoretinal Cataract System, CENTURION Vision System with Active Sentry, Anterior segment ophthalmic surgery
- Where
- 5 sites in United States
- Sponsor
- Alcon Research
Phacoemulsification, Complications
First Postoperative Day Review After Uneventful Phacoemulsification
The purpose of this randomized trial was to examine the value of the review on the first postoperative day after uneventful phacoemulsification cataract surgery.
- Conditions
- Phacoemulsification, Complications, BCVA
- Trial name
- NCT01247155
- Where
- Greece
- Sponsor
- Veroia General Hospital
Cataract, Phacoemulsification
Comparison of Manual Super Small Incision Cataract Surgery and Phacoemulsification
The purpose of this study is to compare the safety and efficacy of manual super small incision cataract surgery (MSSICS) and Phacoemulsification.
- Trial name
- NCT01146964
- Testing
- MSSICS, Phacoemulsification
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Wenzhou Medical University
Cataract, Mydriasis
Subconjunctival Atropine and Intracameral Epinephrine for Pupil Dilation in Phacoemulsification
Mydriatic eye drops are routinely used before phacoemulsification but they are not free of drawbacks. Several alternatives were tried to overcome their limitations.
- Conditions
- Cataract, Mydriasis, Adverse Drug Event
- Trial name
- NCT03638726
- Testing
- Atropine sulfate and epinephrine, Topical cyclopentolate and phenylephrine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Dar El Oyoun Hospital
Cataract
Laser Treatment of the Crystalline Lens
The use of a femtosecond laser in cataract surgery that gives equivalent or improved results comapred to conventional phaco-emulsification surgery.
- Trial name
- NCT01001117
- Testing
- LensAR laser surgery, Phaco-emulsification cataract surgery
- Where
- Mexico
- Volunteers
- 75 people
- Sponsor
- LensAR Incorporated
Diabetes, Cataract
Healing of Corneal Incision After Cataract Surgery in Diabetic Patients
The objective of this observational study was to understand the healing of corneal incision after cataract surgery in diabetic patients and its influencing factors.
- Trial name
- NCT07076420
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Zhongnan Hospital
Cataract, Glaucoma
IOP Changes Associated With SICS and Phako
Prospective randomized trial in patients requiring cataract surgery in which IOP, angle anatomy and other demographic and clinical data are compared. Subjects randomized to both MSICS and phakoemulsification
- Trial name
- NCT02642211
- Testing
- cataract surgery
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Robin, Alan L., M.D.
Diabetic Retinopathy, Cataract
Cataract Surgery with Near Normal Eye Pressure in Patients with Diabetic Retinopathy
Diabetes mellitus is a chronic metabolic disease that can lead to visual impairment and eye complications such as diabetic retinopathy and diabetic macular edema.
- Trial name
- NNIOP-PHACO (NCT06617273)
- Testing
- Ophthalmosurgical handpiece with active anterior chamber pressure sensing and regulation
- Where
- Austria
- Volunteers
- 72 people
- Sponsor
- Medical University Innsbruck
Cataracts
Comparison of Two Phacoemulsification-methods: EasyTip 2.2mm vs. Infusion Assisted EasyTip 2.2mm
The aim of this study was to compare the intraoperative efficiency, safety and postoperative outcomes of cataract surgery with two different "high-fluidic" settings.
- Trial name
- NCT01936727
- Testing
- cataract surgery
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Macular Edema
Prophylactic Nepafenac and Ketorolac Versus Placebo in Patients Undergoing Cataract Surgery
Assess prophylactic efficacy of topical non-steroidal anti-inflammatory drops in preventing macular edema. Patient undergoing uncomplicated cataract surgery will be enrolled and randomized to nepafenac, ketorolac, or placebo.
- Trial name
- PNK (NCT01395069)
- Testing
- Nepafenac 0.1%, Ketorolac 0.5%
- Where
- Canada
- Volunteers
- 162 people
- Sponsor
- Queen's University
Diabetes Mellitus
Corneal Changes in Diabetics After Phacoemulsification
This study aims to assess the corneal damage after phacoemulsification and to assess the factors causing it in diabetics in comparison with non-diabetics.
- Trial name
- NCT02548273
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Jawaharlal Institute of Postgraduate Medical Education & Research
Cataract
Intra-Operative Metrics With CENTURION® and INFINITI® Vision Systems
The purpose of this study is to evaluate intra-operative phacoemulsification machine metrics after phacoemulsification with the CENTURION® vision system configuration compared with the INFINITI® vision system configuration.
- Trial name
- NCT01848288
- Testing
- CENTURION® Vision System (CVS), INFINITI® Vision System (IVS)
- Volunteers
- 112 people
- Sponsor
- Alcon Research
Age Related Cataract, Cataract
Effect of Trypan Blue on Corneal Endothelial Cell Count During Phacoemulsification
This randomized controlled trial evaluated the effect of trypan blue on corneal endothelial cell count in patients undergoing phacoemulsification for age-related cataract.
- Trial name
- NCT07735000
- Testing
- Trypan Blue, Phacoemulcification
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Hayat Abad Medical Complex, Peshawar
Non-Proliferative Diabetic Retinopathy
Intravitreal and Intracameral DEX in NPDR
To investigate the effects of intravitreal and intracameral injection of dexamethasone during cataract phacoemulsification in patients with mild to moderate non-proliferative diabetic retinopathy
- Trial name
- NCT06951087
- Testing
- Dexamethasone sodium phosphate
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Affiliated Hospital of Nantong University