Clinical trials: Phacoemulsification Cataract Surgery
Corneal Astigmatism
Limbal Relaxing Incisions Versus Paired 4 mm Clear Corneal Incisions on Steep Meridian During Phacoemulsification
The goal of this is prospective, computer based randomized clinical trial is to compare the efficacy of reduction of the pre-existing corneal astigmatism at the time of cataract surgery in patients admitted in sohag university…
- Trial name
- LRI-CCI (NCT05593263)
- Testing
- surgical correction of astigmatism with cataract
- Volunteers
- 120 people
- Sponsor
- Sohag University
Cataract Extraction
Comparison of Visual Outcomes and Patient Satisfaction After Cataract Surgery and Implantation of ReSTOR and ReZoom IOLs
Cataract is prevalent throughout the world and IOLs are routinely implanted after the extraction of the cataractous lens. It is the most frequently performed surgery in the United States with an estimated 2-3 million procedures…
- Trial name
- NCT00366587
- Testing
- Cataract surgery and IOL implantation
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Medical University of South Carolina
Dry Eye Disease, Dry Eye Syndrome
Comprehensive Study on Dry Eye and Ocular Surface Disease Prior and After Cataract Surgery
Ocular surface disease (OSD), particularly dry eye, is one of the most common conditions seen by ophthalmologists. Dry eye (DE) is a multifactorial disease of the tears and ocular surface that results in symptoms of discomfort…
- Conditions
- Dry Eye Disease, Dry Eye Syndrome, Evaporative Dry Eye, Cataract
- Trial name
- NCT04711642
- Testing
- The study will include three arms, one non interventional and 2 interventions. The intervention arms will include two commercially available sodium hyaluronate 0.1% (Systane ultra plus and Hylo-comod)
- Volunteers
- 100 people
- Sponsor
- Fundación Oftalmológica Los Andes
Corneal Astigmatism, Intraocular Pressure
How Astigmatism Influences Corneal Biomechanics and Intraocular Pressure
The aim of the study was to identify whether preoperative corneal astigmatism can influence corneal biomechanics and the assessment of intraocular pressure (IOP) following micro-incision phacoemulsification.
- Conditions
- Corneal Astigmatism, Intraocular Pressure, Cataract Senile
- Trial name
- NCT03162471
- Testing
- non-contact measurement of intraocular pressure
- Volunteers
- 39 people
- Sponsor
- Medical University of Lodz
Macular Holes
Evaluation of Anatomic and Visual Outcomes of Initially Closed Macular Holes
To evaluate the anatomic and visual outcomes in patients with initially closed macular holes after vitreoretinal surgery and with one to seven years of follow-up.
- Trial name
- NCT01229657
- Where
- China
- Volunteers
- 79 people
- Sponsor
- Sun Yat-sen University
Cataract Surgery
A Prospective Multicenter Study To Assess The Clinical Outcomes Of Current Phacoemulsification Approach To Cataract Extraction Versus The Micor System Device
The purpose of this research study is to evaluate the clinical outcomes of current phacoemulsification approaches to cataract extraction involving high-frequency thermogenic energy versus the use of the MICOR System device using…
- Trial name
- NCT05729477
- Testing
- miCOR System, Phaco Subject Cohort
- Where
- 6 sites in United States
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec, Inc.
Primary Open Angle Glaucoma, Pseudoexfoliative Glaucoma
Phacotrabeculotomy Versus CCI+Phaco in Patients With Borderline Control of Intraocular Pressure
The purpose of the study is to determine whether combined cataract and glaucoma surgery (phacotrabeculotomy)is more effective in lowering intraocular pressure than cataract surgery alone in patients with borderline control of…
- Trial name
- NCT00346931
- Testing
- Phacoemulsification, implantation of intraocular lens, Phacoemulsification, Implantation of IOL, trabeculotomy
- Volunteers
- 9 people
- Sponsor
- Medical University of Vienna
Cataract
Difference Between Three-Dimensional Heads-Up Surgery System and Traditional Surgery Methods in Cataract Surgery
To evaluate the differences between three-Dimensional heads-Up surgery system and traditional surgery methods of cataract surgery
- Trial name
- NCT04839250
- Testing
- heads-up method
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Wenzhou Medical University
Endothelial Cell Loss, Corneal, Cataract and Intraocular Lens (IOL) Surgery
Effect of Vitamin C Supplementation in Corneal Endothelial Damage in Phacoemulsification of Patients with Hard Cataracts
The goal of this clinical trial is to analyze the protective effects of oral ascorbic acid on the corneal endothelial layer undergoing oxidative stress due to phacoemulsification in patients with hard cataracts.
- Trial name
- NCT06781970
- Testing
- Oral Vitamin C
- Where
- 2 sites in Indonesia
- Volunteers
- 120 people
- Sponsor
- Universitas Indonesia
Cataract
A Single Centre Study to Compare the Efficacy and Safety of Femtosecond Laser-Assisted Versus Manual Cataract Surgery
This clinical study is a controlled, open, prospective, single-centre, multi-surgeon eye study to determine the safety and efficacy of intraocular cuts for femtosecond laser assisted lens frag-mentation to support…
- Trial name
- 1103 (NCT01373853)
- Testing
- Lens Fragmentation by means of a femtosecondlaser, Manual Phacoemulsification
- Where
- India
- Volunteers
- 131 people
- Sponsor
- Technolas Perfect Vision GmbH
High Myopia, Low Intraocular Pressure
Improved Operation of Low Intraocular Pressure in Phacoemulsification for Patients With High Myopia Complicated With Cataract
Approximately 60 participants at Eye Hospital of Wenzhou Medical University during October,2021 to January 2022 will be enroll in the investigators' study.
- Trial name
- NCT05201677
- Testing
- Supplement of perfusion fluid through the subiris suspensory ligament space from the lateral incision
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Yune Zhao
Cataract Surgery, Cataract (Post-operative Cataract Surgery Follow-up)
Subincisional Pockets for Sealing Clear Corneal Incisions in Cataract Surgery
The main goal of the sub-incisional pocket (SIP) is to provide a wound seal option during corneal surgery. This retrospective cohort study aims to report the efficacy and safety of SIP among eyes undergoing routine cornea surgery…
- Conditions
- Cataract Surgery, Cataract (Post-operative Cataract Surgery Follow-up), Phacoemulsification Cataract Surgery, Wound Closure Technique
- Trial name
- SIPSIP (NCT07821203)
- Testing
- Sub-Incisional Pocket
- Where
- Philippines
- Volunteers
- 35 people
- Sponsor
- Philippine Eye Research Institute
Cataract
Phaco Versus Small Incision Cataract Surgery (SICS) Health Economic Study
To compare the health economic parameter and clinical outcome of Phacoemulsification with small incision cataract surgery (SICS)
- Trial name
- NCT00762606
- Testing
- Phacoemulsification cataract extraction surgery, Small incision cataract surgery
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Alcon Research
Cataract
Anterior Capsule Polishing Effect on Effective Lens Position
The purpose of this study is to evaluate effects of anterior capsule polishing on effective lens position (ELP) and actual axial movement of the intraocular lens (IOL) by measuring anterior chamber depth (ACD) patients with…
- Trial name
- NCT01598428
- Testing
- anterior capsule polishing
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shandong University
Cataract Extraction
Clinical Evaluation of Intraocular Caliper-assisted Capsulotomy for Age-related Cataract
The purpose of this study is to compare the accuracy of capsulotomy assisted by intraocular caliper and Verion navigation system in phacoemulsification surgery and postoperative visual quality of patients.
- Trial name
- NCT04977115
- Testing
- Intraocular caliper-assisted capsulotomy, Verion navigation system-assisted capsulotomy
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Cataracts
Endothelial Cell Loss After Phacoemulsification Intra and Supracapsular
Cataract is the clouding of the lens of the eye, which initially prevents clear vision and eventually progresses to blindness if left untreated.
- Trial name
- PERCEPOLIS (NCT02535819)
- Testing
- Subluxation, Divide and Conquer
- Where
- France
- Volunteers
- 294 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Cataract
Registry of PHAcoemulsification for Cataract Surgery
Cataracts cause vision loss due to opacities in the lens. Cataract surgery is performed by emulsifying the nucleus of the lens. A phacoemulsifier is the machine used to deliver ultrasonic energy in the eye to fragment the lens…
- Trial name
- ROPHACS (NCT06659419)
- Where
- France
- Volunteers
- 100,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cataract
Impact of 0.1% and 0.2% Sodium Hyaluronate on Postoperative Discomfort Following Phacoemulsification Surgery
Primary objective of the study is the assessment of the patients' discomfort following cataract extraction surgery by means of phacoemulsification and intraocular lens implantation.
- Trial name
- NCT03705949
- Testing
- Sodium Hyaluronate 0.1% drops, Sodium Hyaluronate 0.2% drops
- Where
- Greece
- Volunteers
- 180 people
- Sponsor
- Democritus University of Thrace
Cataract Extraction, Phacoemulsification
A Study Comparing Two Monofocal, Aspheric, Hydrophobic Acrylic Intraocular Lenses: the Alcon CLAREON® and the Abbott Medical Optics PCB00
This is a bilateral randomised controlled study to compare visual performance, refractive outcome, forward light scatter, patient satisfaction and objective measurement of glistenings following insertion of two monofocal…
- Conditions
- Cataract Extraction, Phacoemulsification, Glistenings, Intraocular Lens Implant
- Trial name
- NCT03364972
- Testing
- Cataract surgery
- Where
- United Kingdom
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Quality of Ocular Akinesia (Onset and Duration)
Efficacy and Safety of Adding Atracurium to Percaruncular Block for High Myopes Undergoing Cataract Surgery
There are several local anesthetic techniques available for cataract surgery and the choice depends on patient, surgical and operator factors.
- Trial name
- NCT03243500
- Testing
- Atracurium, Lidocaine 2%, Bupivacaine 0.5%
- Where
- Egypt
- Volunteers
- 91 people
- Sponsor
- Kasr El Aini Hospital