Clinical trials: Phantom Limb Pain (PLP)
Phantom Limb Pain After Amputation
Preventing Chronification of Phantom Limb Pain Through Mirror Therapy in Conjunction With tDCS
Background: Most amputees experience phantom limb pain (PLP), for years after amputation. Virtually all PLP research to date has focused on the mechanisms of chronic PLP, ignoring the mechanisms of chronification.
- Trial name
- NCT07139483
- Testing
- Trans Direct-Cranial Stimulation (tDCS), Mirror therapy
- Where
- 3 sites in Israel
- Volunteers
- 108 people
- Sponsor
- University of Haifa
Phantom Limb Pain
Massage Therapy for Phantom Limb Pain: Feasibility and Pilot Study
Massage therapy is a treatment self-reported by those with phantom limb pain (PLP) as moderately to extremely effective, but no research to date has been specifically designed to examine such efficacy or effectiveness in this…
- Trial name
- NCT03372668
- Testing
- massage therapy combined with components of mirror therapy
- Volunteers
- 3 people
- Sponsor
- Indiana University
Phantom Limb Pain
Incidence and Factors Affecting the Development and Outcome of Phantom Limb Pain (PLP) - A Single-centre Prospective Cohort Study.
Phantom limb pain (PLP), defined as pain felt in the missing portion of the amputated limb following amputation, occurs in a significant percentage of patients who undergo limb amputation and it is among the most difficult…
- Trial name
- NCT05005481
- Testing
- NIL intervention
- Where
- Singapore
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Pain Management
A Non-invasive Intervention (BreEStim) for Management of Phantom Limb Pain (PLP) After Limb Amputation (Experiment 3)
The purpose of this study is to compare the effectiveness of innovative intervention of breathing controlled electrical stimulation (BreEStim) and conventional electrical stimulation (EStim) in management of neuropathic phantom…
- Trial name
- NCT04751526
- Testing
- BreEStim 240, EStim 240
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- The University of Texas Health Science Center, Houston
Pain Management
A Non-invasive Intervention (BreEStim) for Management of Phantom Limb Pain (PLP) After Limb Amputation (Experiment 1)
The purpose of this study is to compare the effectiveness of innovative intervention of breathing controlled electrical stimulation (BreEStim) and conventional electrical stimulation (EStim) in management of neuropathic phantom…
- Trial name
- NCT04750525
- Testing
- BreEStim, EStim
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The University of Texas Health Science Center, Houston
Phantom Limb Pain (PLP), Primary/Secondary Scar Hyperalgesia
A Trial of Lidocaine Patch for Lower Limb Amputation Pain
Phantom limb pain (PLP) and scar hyperalgesia (SH) are frequent problems after amputation; in particular most persons who undergo limb amputation will experience phantom pain.
- Trial name
- NCT02696720
- Testing
- Lidocaine
- Where
- 2 sites in Belgium
- Sponsor
- Brugmann University Hospital
Residual Limb Pain, Stump Pain
Post-Amputation Stump Infection as a Predictor of Persistent Residual Limb Pain: A Prospective Cohort Study
Persistent residual limb pain is common after traumatic amputation and significantly impairs rehabilitation and prosthetic use. Postoperative stump infection may contribute to peripheral nerve sensitization, scar fibrosis, and…
- Conditions
- Residual Limb Pain, Stump Pain, Post-Amputation Pain, Surgical Site Infection
- Trial name
- INF-STUMP-PAIN (NCT07438795)
- Volunteers
- 150 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
Phantom Limb Syndrome With Pain
Clinical Trial Exploring the Outpatient Treatment of Phantom Limb Pain With Ketamine Administration in a Six Month Study With a Minimum Remission Period of 7 Days Between Treatment Session. 25-30 Subjects With an Ongoing History of Significant PLP.--FDA and IRB Approved.
Must be living Within a 50 mile radius of our study sites: Bay Area, Los Angeles, Albuquerque, Sacramento, Los Angeles An anecdotal report with administration of ketamine in a non-clinical setting providing and sustained…
- Trial name
- PLP (NCT07276542)
- Testing
- IM ketamine in dose finding and then continuation
- Where
- 4 sites in United States
- Volunteers
- 30 people
- Sponsor
- The Ketamine Research Foundation
Phantom Limb Pain (PLP)
Immersive Healing: The Therapeutic Potential of Virtual Reality
Phantom limb pain (PLP) is a significant and pervasive issue among upper limb amputees, severely impacting their quality of life.
- Trial name
- NCT06077227
- Testing
- virtual reality therapy, matched control group
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Wake Forest University Health Sciences
Phantom Limb Pain
Phantom Motor Execution Via MPR, VR/AR, and SG, as a Treatment of PLP
This international, multi-center, double-blind, randomized, controlled clinical trial aims to evaluate the efficacy of Phantom Motor Execution (PME) and Phantom Motor Imagery (PMI) as treatments of Phantom Limb Pain (PLP).
- Trial name
- NCT03112928
- Testing
- Phantom Motor Execution, Phantom Motor Imagery
- Where
- 9 sites in United States, Canada and 5 more
- Volunteers
- 77 people
- Sponsor
- Integrum
Pain Management
A Non-invasive Intervention (BreEStim) for Management of Phantom Limb Pain (PLP) After Limb Amputation (Experiment 2)
The purpose of this study is to compare the effectiveness of innovative intervention of breathing controlled electrical stimulation (BreEStim) and conventional electrical stimulation (EStim) in management of neuropathic phantom…
- Trial name
- NCT04750538
- Testing
- BreEStim 120, BreEStim 240
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- The University of Texas Health Science Center, Houston
Phantom Limb Pain
Long-term Effects of Transcranial Direct Current Stimulation (tDCS) on Patients With Phantom Limb Pain (PLP)
Phantom limb pain (PLP) refers to pain in a limb that has been amputated or deafferented. Phantom limb pain might be related to brain cortical plastic changes.
- Trial name
- NCT02051959
- Where
- Israel
- Volunteers
- 24 people
- Sponsor
- Sheba Medical Center