Clinical trials: Pharmaceutical Care
Hypertansion
Generative AI-Supported Personalized Education Compared With Printed Material for Adults With Hypertension
This study evaluates whether generative artificial intelligence-supported personalized education can improve hypertension knowledge and medication adherence in adults with hypertension compared with standard printed educational…
- Trial name
- GenAI-HYPER (NCT07776834)
- Testing
- Standard Hypertension Education, Generative AI-Supported Personalized Hypertension Education
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Akdeniz University
Primary Care, Health Services Utilization
Study on Primary Care Health Service Utilization in Hong Kong
The aim of this study was to find out the utilization rate and pattern of primary health care services, and the process and outcomes of primary care consultations of the general population in Hong Kong, and whether having a…
- Conditions
- Primary Care, Health Services Utilization, Family Practice
- Trial name
- NCT01422031
- Where
- China
- Volunteers
- 3,148 people
- Sponsor
- The University of Hong Kong
Clinical Sepsis
Improving Morbidity During Post-Acute Care Transitions for Sepsis
The purpose of this study is to improve transitions of care for the highest risk, complex patients with suspected sepsis. Atrium Health has developed a nurse-navigator facilitated care transition strategy, called the Sepsis…
- Trial name
- IMPACTS (NCT03865602)
- Testing
- Sepsis Transition And Recovery (STAR), Usual care
- Where
- United States
- Volunteers
- 712 people
- Sponsor
- Wake Forest University Health Sciences
Polypharmacy, Adverse Drug Reaction
Deprescribing of Symptomatic Medications in Rehabilitative or Subacute Care Patients
Deprescribing is a systematic method of withdrawing potentially inappropriate or unnecessary medications and is warranted in the elderly due to the high prevalence of polypharmacy.
- Trial name
- NCT03354845
- Testing
- Deprescribing intervention
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bright Vision Hospital
Metastatic Prostate Cancer
The Present Study Aims to Compare Patients Who Receive the Investigational Product (177Lu-DOTA-rosopatamab) Plus Standard of Care, in Comparison to Standard of Care Only
This multinational, multicenter, prospective, randomized, controlled, open label Phase 3 study is designed to investigate and confirm the benefits and risks associated with the PSMA-targeted antibody, 177Lu DOTA rosopatamab…
- Trial name
- NCT04876651
- Testing
- 177Lu-DOTA-rosopatamb, Standard of Care
- Where
- 6 sites in Australia, New Zealand
- Volunteers
- 16 people
- Sponsor
- Telix Pharmaceuticals (Innovations) Pty Ltd
Acute Bacterial Skin and Skin Structure Infection (ABSSSI), Non-healing Wound
Phase 2 Randomized Study to Compare Ultrasonic Drug Delivery to Standard of Care for the Treatment of Infections in Non-Healing Wounds
This is a randomized study to compare the safety and efficacy of a single dose of up to 2 grams of cefazolin administered using a new drug delivery method called Ultrasonic Drug Delivery (UDD), combined with standard of care…
- Trial name
- NCT03732365
- Testing
- Ultrasonic Drug Delivery, Standard of Care Antibiotic Treatment
- Volunteers
- 30 people
- Sponsor
- Sonescence, Inc.
Acute Disease, Sepsis
Acutelines: a Large Data-/Biobank of Acute and Emergency Medicine
Research in acute care faces many challenges, including enrollment challenges, legal limitations in data sharing, limited funding, and lack of singular ownership of the domain of acute care.
- Conditions
- Acute Disease, Sepsis, Pneumonia, Frailty
- Trial name
- Acutelines (NCT04615065)
- Where
- Netherlands
- Volunteers
- 35,000 people
- Sponsor
- University Medical Center Groningen
HIV Infections
The Effect of Teaching HIV-Infected Patients About HIV and Treatment
The purpose of this study is to see if an HIV-education course can help under-represented, HIV-infected patients. This study examines the areas of faithfulness to drug regimen, level of HIV in the blood, and health status.
- Trial name
- NCT00002409
- Testing
- Lamivudine/Zidovudine, Abacavir sulfate
- Where
- 25 sites in United States
- Volunteers
- 200 people
- Sponsor
- Glaxo Wellcome
Cholangitis, Secondary Biliary, Treatment Compliance
Antibiotics Treatment of Cholangitis Post-Kasai Portoenterostomy
Application of multi-center, prospective study on the severity of postoperative cholangitis biliary atresia classification, according to the degree of cholangitis targeted therapy, to improve the therapeutic effect of…
- Conditions
- Cholangitis, Secondary Biliary, Treatment Compliance, Antibodies Drug Specific
- Trial name
- NCT04370145
- Testing
- Sulperazon, Teicoplanin, Meropenem Injection
- Where
- 2 sites in China
- Volunteers
- 160 people
- Sponsor
- Tongji Hospital
Traumatic Brain Injury, Subdural Hematoma
Hypernatremia for the Prevention and Treatment of Cerebral Edema in Traumatic Brain Injury
Cerebral edema is seen heterogenous group of neurological disease states that mainly fall under the categories of metabolic, infectious, neoplasia, cerebrovascular, and traumatic brain injury disease states.
- Conditions
- Traumatic Brain Injury, Subdural Hematoma, Cerebral Contusion, Head Injury
- Trial name
- NCT01605357
- Testing
- Induced, sustained hypernatremia using hypertonic saline, Standard of care (hypertonic saline and mannitol; serum sodium)
- Sponsor
- Massachusetts General Hospital
Poison;Medicinal, Extracorporeal Membrane Oxygenation
Treatment of Extracorporeal Membrane Oxygenation in Severe Poisoning
This is a prospective, multicentre clinical study to determine the value of the Extracorporeal Membrane Oxygenation in the treatment of critically ill poisoning patients and whether there are significant differences in the…
- Trial name
- NCT05762029
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Affiliated Hospital of Nantong University
Chronic Disease, Medication Adherence
Impact of Pillboxes on Medical Adherence
This study uses an experimental design to test the impact of different types of pillboxes on medication adherence. Participants in this study will randomized to receive one of the three pillbox interventions: 1) A standard seven…
- Trial name
- NCT03861845
- Testing
- Standard off-the-shelf pillbox, Custom off-the-shelf pillbox, Custom designed and manufactured pillbox
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Florida International University
Primary Open-Angle Glaucoma (POAG)
Personalized Mobile Reminders for Medication Adherence and Intraocular Pressure Control in Primary Open-Angle Glaucoma
This study evaluates whether a personalized mobile reminder program improves treatment adherence and clinical outcomes in adults with primary open-angle glaucoma (POAG) using topical antiglaucoma eye drops.
- Trial name
- M-GLAUCO (NCT07480577)
- Testing
- Digital Reminder Intervention
- Volunteers
- 84 people
- Sponsor
- Sakarya Yenikent State Hospital
Type 2 Diabetes
Nutritional Therapy and Education With Multimedia Application in Patients With Type 2 Diabetes
The purpose of this study is to evaluate the effectiveness of nutrition therapy in combination with education in diabetes using a multimedia application for improving indicators of metabolic control in patients with type 2…
- Trial name
- NCT02441023
- Testing
- Nutritional therapy and education, Nutritional therapy
- Where
- Mexico
- Volunteers
- 306 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Depression
Pharmaceutical Care Program for Pharmacological Treatment of Depression in Primary Care
The purpose of this study is to evaluate the impact of pharmaceutical services among patients starting a treatment with antidepressants for a diagnosis of depression.
- Trial name
- PRODEFAR (NCT00794196)
- Testing
- Pharmaceutical care program for antidepressant treatment
- Where
- 2 sites in Spain
- Volunteers
- 179 people
- Sponsor
- Fundació Sant Joan de Déu
Occupational Stress or Workplace Stress, Exhaustion, Caregiver
Feasibility of Body Acupuncture for Stress, Burnout, Sleep Quality and Wellbeing: A Pilot Study
This pilot study investigates the acceptability and effects of traditional Chinese medicine (TCM) body acupuncture on stress and exhaustion among healthcare professionals working in an acute care hospital.
- Trial name
- TCM-ACU-PILOT (NCT07818837)
- Testing
- Traditional Chinese Medicine Body Acupuncture
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Swiss University for Traditional Chinese Medicine
Medication Adherence, Hypertension
Optimizing the Approach of Mobile Application Use to Improve Medication Adherence in Patients With Hypertension
The purpose of this study was to determine the effectiveness of using a custom-designed mobile application to improve blood pressure (BP) and promote adherence to antihypertensive medication regimens.
- Trial name
- NCT04066010
- Testing
- Mobile application (BP-n-Me)
- Volunteers
- 55 people
- Sponsor
- Mercer University
Home-based Care Service, Hospice Care Needs
Survey on Home-Based Hospice Care Service Needs
This study aims to investigate and analyze the demand for "Internet +" integrated TCM-Western medicine home-based hospice care across different populations, in order to evaluate the local region's awareness, demand levels, market…
- Trial name
- NCT07815041
- Where
- China
- Volunteers
- 1,229 people, healthy volunteers welcome
- Sponsor
- Emeishan Hospital of Traditional Chinese Medicine
Medication Adherence, HIV Prevention
Single Dose Truvada Study
This study examines tenofovir (TFV) drug concentrations in adults one day after taking a single dose of Truvada® - a pill used to prevent and treat HIV infection.
- Trial name
- NCT03719053
- Testing
- Tenofovir
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Drug Resistance
Aspirin and Clopidogrel Resistance Study
Resistance to antiplatelet drugs (aspirin, clopidogrel) is a recognized phenomenon with a prevalence from 17% to 35%. Resistance as detected by in vitro tests such as Multiple Electrode Aggregometry (MEA) has been shown to…
- Trial name
- NCT01039480
- Where
- Switzerland
- Volunteers
- 82 people
- Sponsor
- University Hospital, Basel, Switzerland