Clinical trials: Pharmaceutical Preparations
Healthy Volunteers
A Study to Compare the Bioavailability (BA) of Dexlansoprazole Delayed-release Capsules
The purpose of this study is to assess the BA of 30 or 60 milligram (mg) dexlansoprazole capsule manufactured at TOB (Takeda GmbH Plant Oranienburg) to the corresponding 30 or 60 mg dexlansoprazole manufactured at TPC (Takeda…
- Trial name
- NCT03801148
- Testing
- 30 mg dexlansoprazole capsules manufactured at TOB, 30 mg dexlansoprazole capsules manufactured at TPC, 60 mg dexlansoprazole capsules manufactured at TOB
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Takeda
Healthy Adult Participants
Safety, Tolerability and Pharmacokinetics Study of L608 in Healthy Adults
This is a single ascending dose study of L608 in healthy participants and is being conducted to evaluate the safety of L608 with dose level ranging from 10 μg to 20 μg.
- Trial name
- NCT06429930
- Testing
- L608 Liposomal inhalation suspension
- Where
- New Zealand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pharmosa Biopharm Inc.
Influenza
Project to Investigate Ways to Reduce the Spread of Influenza in Schools and Households With Children
The purpose of this study is to understand the spread of influenza (flu) in schools and households with elementary (K-5) school children, and develop ways to reduce the flu using non-pharmaceutical means.
- Trial name
- PIPP (NCT00446628)
- Testing
- behaviors reducing spread of influenza
- Where
- United States
- Volunteers
- 3,360 people, healthy volunteers welcome
- Sponsor
- Kiren Mitruka
Healthy Volunteers
Bioequivalence Study of Dexlansoprazole Capsules From Two Manufacturing Plants
The purpose of this study is to assess the bioavailability of dexlansoprazole from a 30 milligram (mg) or 60 mg delayed-release capsule manufactured at Takeda GmbH Plant Oranienburg, Germany (TOB) relative to that of…
- Trial name
- NCT03131895
- Testing
- 30 mg dexlansoprazole capsules manufactured at TOB, 30 mg dexlansoprazole capsules manufactured at TPC, 60 mg dexlansoprazole capsules manufactured at TOB
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Takeda
Healthy
Non-pharmaceutical Motion Sickness Mitigation
The purpose of this study is evaluate the effect of timing and magnitude on the administration of our nonpharmaceutical treatment to motion sickness, and to evaluate the effect of Galvanic Vestibular Stimulation (GVR) amplitude…
- Trial name
- NCT04859868
- Testing
- Galvanic Vestibular Stimulation
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Exposure, Radiation
Preparation of Radiopharmaceuticals by Automaton: Operators Dosimetry
The radiopharmaceuticals manipulation used in nuclear medicine department is a significant source of radiation for operators. According to Article R.
- Trial name
- AUTOTEC (NCT03974256)
- Testing
- Training in the use of the automaton
- Where
- France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Healthy
Bioequivalence Study of Favipiravir From Flupirava 200 mg Tablet (European Egyptian Pharmaceutical Industries , Egypt) Versus Avigan 200 mg Tablets (Man. by Toyama Chemical Co., Ltd Japan)
An open label randomized, single dose, two-way crossover bioequivalence study to determine the bioequivalence of Favipiravir from Flupirava 200 mg tablet (European Egyptian Pharmaceutical Industries, Egypt) versus Avigan 200 mg…
- Trial name
- NCT04478448
- Testing
- Flupirava, Avigan
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Genuine Research Center, Egypt
Medical Education, Health Education
Idea Density in Exam Performance
Text can be written in multiple ways to mean the same thing; changing how a text is written can make it easier or harder to understand.
- Conditions
- Medical Education, Health Education, Educational Assessment
- Trial name
- IDEP (NCT05526365)
- Testing
- Reduced Idea Density
- Where
- United Kingdom
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Healthy
Bioequivalence Study of Torrent Pharmaceutical Ltd's Esomeprazole Magnesium Delayed Release Capsules
Subjects to compare the single dose bioavailability of Torrent's Esomeprazole Delayed Release Capsule 1 × 40 mg and Nexium 1× 40 mg of AastraZeneca LP, USA. Dosing periods of studies were separated by a washout period of 7 days.
- Trial name
- NCT02680132
- Testing
- Nexium 40 mg DR Capsules of AstraZeneca LP, USA, Torrent's Esomeprazole Magnesium DR Capsules 40 mg
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Torrent Pharmaceuticals Limited
Healthy
Bioequivalence Study of Torrent Pharmaceutical Ltd.'s of Escitalopram Oxalate Tablets Under Fasting Condition
Objective: Primary objective of the present study was to compare the single dose bioavailability of Torrent's Escitalopram Oxalate Tablet 20 mg [Test formulation, Torrent Pharmaceuticals Ltd., India] Versus Lexapro® (Escitalopram…
- Trial name
- NCT01996462
- Testing
- Escitalopram Oxalate Tablets
- Where
- India
- Volunteers
- healthy volunteers welcome
- Sponsor
- Torrent Pharmaceuticals Limited
Healthy
Bioequivalence Study of Torrent Pharmaceutical Limited's Isosorbide Mononitrate 120 mg ER Tablets Under Fed Conditions
Objective: to compare the single dose bioavailability of Torrent's Isosorbide Mononitrate 120 mg ER Tablets (Test) and Isosorbide Mononitrate 120 mg ER Tablets (Reference) of Kremers Urban, USA under fed condition.
- Trial name
- NCT01418547
- Testing
- Torrent's Isosorbide Mononitrate 120 mg ER Tablets
- Where
- 2 sites in India
- Volunteers
- healthy volunteers welcome
- Sponsor
- Torrent Pharmaceuticals Limited
To Determine Bioequivalence Under Fed Conditions
Bioequivalence Study of Doxycycline Monohydrate Tablets Under Fed Conditions
The purpose of this study is to compare the single-dose bioequivalence of Par and Oclassen doxycycline monohydrate 100 mg.
- Trial name
- NCT01380496
- Testing
- doxycycline monohydrate
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Par Pharmaceutical, Inc.
Renal Transplantation
A Study to Compare the Pharmacokinetics of Belatacept Using Active Pharmaceutical Ingredient Manufactured by Process E Relative to Process C
The purpose of the study is to compare the Pharmacokinetics (PK) of Process E belatacept relative to Process C belatacept in Healthy subjects
- Trial name
- NCT02564497
- Testing
- Process E Belatacept, Process C Belatacept
- Where
- United States
- Volunteers
- 491 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Healthy
Open-label Crossover Metformin Gum Versus Tablet in Healthy Volunteers
Single-dose, randomized, open-label, cross over study. The study will have an open-label, 3 period, 3 treatments, and randomized design.
- Trial name
- NCT00648869
- Testing
- metformin tablet, metformin gum
- Where
- Israel
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Healthy
Bioequivalence Study of Torrent Pharmaceutical Ltd.'s Rabeprazole Sodium Delayed Release Tablets Under Fed Conditions
Objective: Primary objective of the present study was to compare the single dose bioavailability of Torrent's Rabeprazole Sodium Delayed Release Tablets 20 mg and Aciphex® Delayed Release Tablets 20 mg (Reference, Eisai Inc.…
- Trial name
- NCT01990586
- Testing
- Rabeprazole sodium 20 mg Delayed Release tablet
- Where
- India
- Volunteers
- healthy volunteers welcome
- Sponsor
- Torrent Pharmaceuticals Limited
Shoulder Pain
Biopsychosocial Influence on Shoulder Pain
Chronic shoulder pain is a common, costly, and disabling problem for society. The identification of factors predictive of the development of chronic shoulder pain is necessary to develop innovative and effective treatments to…
- Trial name
- BISP (NCT02620579)
- Testing
- Propranolol LA (60 mg), Shoulder Anatomy Education, Pain Processing Education
- Where
- United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Duke University
Bioavailability and Pharmacokinetics
To Assess Dose Proportionality and Pharmacokinetic Linearity of Saninova Tablets in Healthy Participants Under Fasting Conditions
An open-label, randomized, single dose study to assess dose proportionality and pharmacokinetic linearity in healthy participants under fasting condition.
- Trial name
- Saninova (NCT07664657)
- Testing
- Vitamin C, Vitamin B2, Astragalus Root dry extract etc
- Where
- India
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sichuan Credit Pharmaceutical Co., Ltd.
Healthy
Bioequivalence Study of Fenofibrate Capsules, 130 mg Under Fasting Conditions
The study was conducted as an open label, balanced, randomized, two-treatment, two-period, two-sequence, crossover bioequivalence study comparing a single oral dose of fenofibrate capsules, USP 130 mg, of Ohm Laboratories Inc.
- Trial name
- NCT02306889
- Testing
- Fenofibrate, ANTARA® (fenofibrate)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ranbaxy Laboratories Limited
Covid-19, SARS Pneumonia
Assess the Safety and Immunogenicity of NDV-HXP-S Vaccine in Thailand
This study will be conducted in 2 phases. Phase 1 designed to evaluate safety, tolerability and immunogenicity COVID-19 vaccine (NDV-HXP-S) administered at different doses levels (1, 3, and 10 µg) without adjuvant, and at two…
- Conditions
- Covid-19, SARS Pneumonia, Pneumonia, Viral, Covid-19 Vaccine
- Trial name
- NCT04764422
- Testing
- Normal Saline, NDV-HXP-S vaccine
- Where
- Thailand
- Volunteers
- 455 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Parkinson Disease
Bioavailability and Bioequivalence Between Two Active Pharmaceutical Ingredient (API) Sources of Opicapone (OPC)
This study evaluates the bioavailability and bioequivalence between two active pharmaceutical ingredient (API) sources of opicapone (OPC) at two different dosage strengths (50 mg and 25 mg) after single and multiple dose…
- Trial name
- NCT04265027
- Testing
- 50 mg BIA 9 1067, 25 mg BIA9 1067, 50 mg Ongentys
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Bial - Portela C S.A.