Clinical trials: Pharyngeal Dysphagia
Esophageal Motility Disorders
Codeine on Pharyngeal and Esophageal Motility
Opioids act on opioid receptors located in the brain as well as in the gastrointestinal (GI) tract to induce changes in motility.
- Trial name
- NCT03784105
- Testing
- Codeine Phosphate, Siripus simplex
- Where
- 2 sites in Belgium
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Oropharyngeal Dysphagia
Effect of Pharyngeal Inhibition by rTMS on Swallowing Function
The aim of this study is to test the hypothesis that rTMS on the dominant swallowing hemisphere is able to modify swallowing coordination.
- Trial name
- rTMSvideoSS (NCT02170454)
- Testing
- magnetic stimulation
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Critical Illness, Dysphagia
Detection of Neuromuscular Complications in Critically Ill Patients
Dysphagia and the intensive care unit-acquired weakness (ICU-AW) are common and outcome-relevant neuromuscular complications in critically ill patients, especially after prolonged mechanical ventilation, sepsis and multi-organ…
- Conditions
- Critical Illness, Dysphagia, Intensive Care Unit Acquired Weakness, Neuromuscular Diseases
- Trial name
- NMCiCIP (NCT04541602)
- Where
- Germany
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Rostock
Deglutition Disorders
A New Ultrasound Score for Swallowing Disorders Diagnosis in Difficult-to-wean Tracheostomised Patients
Swallowing Disorders (SD) is commonly observed in intensive care unit (ICU) patients. Disruption to the upper airway by way of a tracheostomy may lead to physiological and/or biomechanical changes to the swallow, thereby…
- Trial name
- SHUBACA (NCT06630013)
- Where
- 4 sites in France
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Hopital Forcilles
Chronic Obstructive Pulmonary Disease
Decreased Tongue Strength is Related to Skeletal Muscle Mass in COPD Subjects
Background: Dysphagia is frequently observed in subjects with chronic obstructive pulmonary disease (COPD). But tongue strength has not been investigated yet in COPD subjects.
- Trial name
- NCT04761380
- Testing
- balloon-based tongue pressure measurement device
- Where
- Japan
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Kindai University
Dysphagia, Healthy Aging
Swallowing Impairments in ICU Survivors and Community-Dwelling Adults
Post-intensive care syndrome (PICS), which consists of physical, cognitive, and psychosocial problems, is a pervasive complication for older intensive care unit (ICU) survivors and contributes to detrimental health outcomes and…
- Conditions
- Dysphagia, Healthy Aging, Post Intensive Care Syndrome, Caregiver Burden
- Trial name
- NCT07005037
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Swallowing Disorder
Compare Swallowing Kinematics and Suprahyoid Muscle Activation Among Three Different Swallowing Tasks
The aim of this study is to swallowing kinematics and suprahyoid muscle activation among Masako, Mendelsohn Maneuvers and new-designed Mouth Open Swallowing Maneuver
- Trial name
- NCT05579041
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Swallowing Disorders
Modelling of Pharyngeal Laryngeal Effectiveness
The purpose of this study is to collect the signals of pharyngeal laryngeal activity through five non-invasive sensors (microphone, accelerometer, surface electromyography (EMG), nasal cannula and oximeter) in order to identify…
- Trial name
- Eph-L (NCT06014710)
- Testing
- Swallowing evaluation
- Where
- 4 sites in France
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Deglutition Disorders, Stroke
Computerized Acoustic Swallowing Evaluation
It is the purpose of this study to determine if a commercially available electronic stethoscope synchronized with an smart phone or iPad application can be used as an accurate and objective screening tool for measuring dysphagia.
- Trial name
- CASE (NCT02925507)
- Testing
- Swallowing Screen
- Volunteers
- healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Dysphagia, Intervention
Swallowing Difficulties in People Over 60 Years: Prevalence, Degree of Difficulty and Intervention
Participants included in SCAPIS2 (Swedish Cardio Pulmonary bioimage study) are screened regarding swallowing difficulty using a timed water swallow test.
- Conditions
- Dysphagia, Intervention, Ageing
- Trial name
- NCT06599021
- Testing
- Muscular strengthening training, Skill-based training
- Where
- Sweden
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Lisa Tuomi
Parkinson's Disease
Cough According to Stimulus Type in PD
Aspiration pneumonia (APn) occurs at a higher rate in patients with Parkinson's disease (PD) versus healthy adults. This is of particular public health concern given that death secondary to aspiration pneumonia and lung infection…
- Trial name
- NCT02390089
- Testing
- Capsaicin vapor, fog, Videofluoroscopic swallow evaluation
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- University of Florida
Dysphagia, Swallowing Disorders
Novel Pharyngeal Metrics to Predict Dysphagia Outcomes
This multi-site trial will follow a cohort of Veterans with dysphagia for 8 weeks as they undergo clinically guided oropharyngeal exercises with oropharyngeal strengthening as the primary goal.
- Trial name
- NCT04569097
- Testing
- standard of care lingual strengthening
- Where
- 3 sites in United States
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Head and Neck Neoplasms, Swallowing Sparing IMRT
The SWOAR Trial Sparing of Swallowing and Aspiration Related Organs at Risk & Submandibular Gland With Intensity Modulated Radiotherapy Versus Standard IMRT in Head and Neck Squamous Cell Carcinomas
The aim of SWOAR TRIAL is to test sparing of Dysphagia/ Aspiration risk structures (DARS) and contra lateral submandibular gland by IMRT.
- Trial name
- SWOAR (NCT05187091)
- Testing
- Swallowing and submandibular sparing IMRT, Standard IMRT with medical CRT/RT, Cisplatine
- Where
- India
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences
Dysphagia
AI-Based Dysphagia Rehabilitation Program: Development and Validation
The goal of this clinical study is to learn if an artificial intelligence (AI)-assisted swallowing rehabilitation program can improve swallowing function in adults with dysphagia.
- Trial name
- NCT07767123
- Testing
- Neuromuscular electrical stimulation for swallowing, Multi-sensor swallowing screening for dysphagia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Research Center for Rehabilitation Technical Aids
Cough, Vocal Cord Atrophy
Usefulness and Feasibility of Ultrasound in Office Laryngology Procedures
Investigators will assess the usefulness of using ultrasound in office procedures for laryngology interventions. Participants who qualify will be adults who are undergoing superior laryngeal nerve block, injection laryngoplasty…
- Conditions
- Cough, Vocal Cord Atrophy, Vocal Cord Paresis, Vocal Cord Paralysis
- Trial name
- NCT06579989
- Testing
- Ultrasound for cough, Ultrasound for vocal fold atrophy or vocal fold paresis/paralysis, Ultrasound for dysphagia
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Functional Voice and Swallowing Outcomes
Swallowing and Voice Outcomes After Thyroidectomy
Impairment in voice and swallowing functions are common after thyroidectomy. The investigators aimed to evaluate the objective functional voice and swallowing outcomes in a series of patients undergoing thyroidectomy.
- Trial name
- NCT03436186
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Ege University
Otorhinolaryngologic Disease, Otorhinolaryngologic Neoplasm
Ultrasound Evaluation of Tongue Movements in Speech and Swallowing
This study will assess the use of ultrasound-a test that uses sound waves to produce images-as a diagnostic tool for evaluating speech and swallowing.
- Conditions
- Otorhinolaryngologic Disease, Otorhinolaryngologic Neoplasm, Pharyngeal Neoplasm, Polymyositis
- Trial name
- NCT00001167
- Where
- United States
- Volunteers
- 570 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Dysphagia, Oropharyngeal, Stroke
Screening of Dysphagia Via Ultrasonography in Patients With Stroke
Oropharyngeal dysphagia is commonly seen in patients with stroke. Clinical assessment may be used to evaluate dysphagia in patients with stroke however reliability of this method is controversial and videofluoroscopic study is…
- Trial name
- NCT04344392
- Testing
- Ultrasonographic study, Videofluoroscopic study temporal parameters, Videofluoroscopic study distance parameters
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Dysphagia, Stroke
Fostering Eating After Stroke With Transcranial Direct Current Stimulation
Swallowing difficulties are common after a stroke and can lead to serious complications like pneumonia and malnutrition. Unfortunately, there are no effective treatment for improving swallowing in stroke patients.
- Trial name
- FEASt (NCT01919112)
- Testing
- tDCS
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Dysphagia
External Pharyngeal Exerciser and Pharyngeal Phase of Swallowing
This study of healthy young and elderly individuals is intended to assess the effects of pharyngeal exerciser on pharyngeal pressure phenomenon during swallowing.
- Trial name
- NCT05708911
- Testing
- Pharyngeal exerciser
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin