Clinical trials: Pharyngitis
Sore Throat, Hoarseness
The Effectiveness of Preemptive Nebulized Dexamethasone in Reducing Post-Operative Sore Throat in Supraglottic Airway
This study aims to study the effectiveness of preoperatively nebulized dexamethasone in reducing the incidence and severity of Post Operative Sore Throat, POST in patients undergoing surgery under general anesthesia using the…
- Conditions
- Sore Throat, Hoarseness, Dexamethasone, Supraglottic Airway Devices
- Trial name
- SGA (NCT04771026)
- Testing
- Dexamethasone
- Where
- Malaysia
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Personal Satisfaction
Evaluating the Clinical Efficacy and Safety of Colflex
This study is designed to test the safety and efficacy of Colflex, an oral spray created by Innotech Nutrition, on human subjects to measure changes on frequency/duration of colds and sore throats, as well as dental and oral…
- Trial name
- NCT02011035
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Laryngeal Masks, Pharyngitis
Postoperative Sore Throat in Children: Comparison Between Two Supraglottic Devices, Ambu® AuraOnce™ Laryngeal Mask Airway (LMA) and I-Gel®.
Sore throat is minor but well recognized complaint after receiving general anaesthesia. It is rated as 8th most undesirable outcome in postoperative period.It not only affects the patient's satisfaction but also can affect…
- Conditions
- Laryngeal Masks, Pharyngitis, Minors, Anesthesia
- Trial name
- NCT03140228
- Testing
- I-Gel, LMA
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Surgery, Nurse's Role
Effects of Aromatic Solution Applied After Surgery
Today, surgical applications are used to solve many health problems. In order for the surgical intervention to take place, anesthesia applications are often required.
- Conditions
- Surgery, Nurse's Role, Throat, Sore, Thirst
- Trial name
- NCT05522023
- Testing
- group treated with aromatic solution, group treated with drinking water
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Post Operative Sore Throat at 6hrs and 24hrs After Endotracheal Intubation
Comparison of Efficacy of Betamethasone Gel With Lidocaine Gel in Prevention of Post Endotracheal Intubation Sore Throat.
The goal of this clinical trial is to compare the incidence of postoperative sore throat in adult patients of either gender belonging to ASA I or II ,undergoing endotracheal intubation using betamethasone gel versus lidocaine…
- Trial name
- NCT07256834
- Testing
- Betamethasone dipropionate 0.05%, Lidocaine hydrochloride 2%
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jinnah Postgraduate Medical Centre
Streptococcus Pyogenes Pharyngitis, Streptococcus Infection
A Strep Throat Controlled Human Infection Trial in Healthy Adults
This aim of this study is to further develop a new way to study the bacteria that causes pharyngitis (strep throat). The scientific name for this bacterium is Streptococcus pyogenes and it is commonly known as Strep A.
- Trial name
- CHIVAS-M1 (NCT06992141)
- Testing
- Streptococcus pyogenes M1UK strain MCRI0102
- Where
- Australia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Murdoch Childrens Research Institute
Streptococcus Pyogenes Pharyngitis, Streptococcus Pharyngitis
Controlled Human Infection for Vaccination Against Streptococcus Pyogenes
Group A Streptococcus (GAS) infection is a major cause of death and disability globally with a disproportionately high burden in settings of disadvantage worldwide.
- Conditions
- Streptococcus Pyogenes Pharyngitis, Streptococcus Pharyngitis, Strep Throat, Streptococcus Pyogenes Infection
- Trial name
- CHIVAS (NCT03361163)
- Testing
- emm75 Streptococcus pyogenes (GAS M75, strain 611024)
- Where
- Australia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Andrew Steer
Tonsillectomy, Tonsillitis
EXPAREL® for Pain After Tonsillectomy
The purpose of this study is to determine whether liposomal bupivacaine (long acting injectable anesthetic) provides greater post operative pain relief compared to the standard post operative pain regiment for tonsillectomy…
- Conditions
- Tonsillectomy, Tonsillitis, Post-operative Pain
- Trial name
- NCT02444533
- Testing
- Liposomal Bupivacaine
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Upper Respiratory Tract Infections, Rhinopharyngitis
Effect of the Consumption of a Fermented Milk on Common Infections in Adults Submitted to Multi-stressor Situation
This multicentric, randomized, double-blind and controlled study aims to examine the effect of a fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 (Actimel® = tested product) on the incidence of…
- Conditions
- Upper Respiratory Tract Infections, Rhinopharyngitis, Sore Throat, Sinusitis
- Trial name
- NCT01315418
- Testing
- 1-Fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 (Actimel®), 2-Non fermented dairy product (control)
- Where
- France
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Acute Otitis Media, Allergic Rhinitis
A Trial of Point of Care Information in Ambulatory Pediatrics
Does presentation of clinical evidence for decision making at point-of-care improve prescribing patterns in ambulatory pediatrics?
- Conditions
- Acute Otitis Media, Allergic Rhinitis, Sinusitis, Constipation
- Trial name
- NCT00368823
- Testing
- Electronic point-of-care delivery system
- Where
- 2 sites in United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Washington
Sore Throat After Thyroid Surgery
Transcutaneous Electrical Acupoint Stimulation on Postoperative Pharyngeal Pain
Thyroid surgery is a common type of surgery in thyroid and breast surgery, mainly used to treat benign and malignant thyroid diseases.
- Trial name
- NCT07117123
- Testing
- Transcutaneous electrical acupoint stimulation, No electrical stimulation
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Sore Throat
Comparing Efficacy Preoperative Nebulized: Ketamine , Mgspo4 ,and Lidocaine In Attenuating Endotracheal Sore Throat
One of the most common complications after endotracheal intubation is sore throat Lidocaine jelly or spray, preoperative gargles with licorice or ketamine or I.V steroids used for prophylaxis against POST are expensive ,and…
- Trial name
- NCT03729973
- Testing
- Ketamine, Magnesium Sulfate, Lidocaine
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Neurocognitive Disorders, Post Operative Delirium
Safe Brain Initiative, Operationalizing Precision Anaesthesia
Perioperatively, patients experience an unnecessarily high level of side effects associated with their treatment. These side effects include nausea, severe pain, anxiety, and stress.
- Conditions
- Neurocognitive Disorders, Post Operative Delirium, Pain, Nausea
- Trial name
- SBI (NCT05765162)
- Testing
- Patient reported ourcomes
- Where
- Denmark
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Rheumatic Heart Disease in Children
School-based Program for the Prevention of Rheumatic Heart Disease in Endemic Regions
The overall objective of the PREVENT trial is to evaluate the effectiveness of an integrated, school-based program for the prevention of rheumatic heart disease (RHD) in regions with an endemic pattern of RHD.
- Trial name
- PREVENT (NCT06720272)
- Testing
- School nurse program
- Where
- 2 sites in Nepal, Zambia
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Thomas Pilgrim
Common Cold, Sore-throat
Efficacy and Safety of Silfamin for Common Cold
This is a 2-arm, prospective, randomized, double-blind, placebo-controlled, and three-days-treatment clinical study comparing the efficacy and safety of Silfamin at a dose of 2 tablets@150 mg twice daily in subjects with common…
- Trial name
- NCT06497439
- Testing
- Silfamin
- Where
- 2 sites in Indonesia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dexa Medica Group
Pharyngitis
Safety, Tolerability, and Pharmacokinetic Profile of Grammidin, a Metered Dose Topical Spray in Healthy Volunteers
This study aims to evaluate the safety, tolerability, and pharmacokinetic profile of the Grammidin, a metered dose topical spray, compared to Grammidin lozenges following single administration in healthy volunteers .
- Trial name
- NCT06859281
- Testing
- Grammidin neo, Grammidin, a metered dose topical spray
- Where
- Russia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Valenta Pharm JSC
Peritonsillar Abscess
Assessing the Necessity of Prescribing Antibiotics (Clavulin or Clindamycin Versus Placebo) Post-peritonsillar Abscess Drainage
This study aims to look at the necessity for prescribing antibiotics post-drainage of peritonsillar abscesses (PTA). This will be a single-blinded randomized-control trial with two arms - patients receiving placebo versus those…
- Trial name
- PTA (NCT01715610)
- Testing
- Clavulin, Clindamycin
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Optic Nerve Diameter, Intracranial Pressure Increase
Effect of Optıc Nerve Dıameter ın Tymphanoplasty Surgery Performed ın Lateral Head Posıtıon
Studies exist to determine the effect of laparoscopic surgical procedures on increased intra-abdominal pressure; these studies include optic nerve sheath diameter (ONSD) measurement in various positions such as trendelenburg and…
- Trial name
- ONSD (NCT07407972)
- Testing
- optic nerve diameter
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Peritonsillar Abscess
Peritonsillar Abscess: Aspiration Versus Tonsillectomy a Chaud
Peritonsillar abscess (PTA) has a relatively high incidence of 41 per 100,000/year in Denmark. In spite of that, there is no regional or national consensus on treatment of PTA.
- Trial name
- NCT03326661
- Testing
- Aspiration, Tonsillectomy a chaud, Penicillin V + metronidazol (Penicillin allergy: Clindamycin alone)
- Where
- Denmark
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Viral Gastro Enteritis, Pharyngitis
Impact of Handing to Patients a Copy of the Consultation Report on Their Medicine Consumption
In France, patients with benign viral infections (ie: gastro enteritis and/or rhinopharyngitis, etc.) often receive several prescriptions from their doctors, although there is evidence that these medicines are not efficient.
- Trial name
- NCT02237573
- Testing
- Written medical report and standardized medical advices, Control
- Where
- France
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University Paris 7 - Denis Diderot