Clinical trials: Phobias
Social Phobia
Social Safety Learning in the Brain Oxytocin System
The investigators are conducting this research study to examine whether oxytocin enhances social safety learning (learning safety through the experience of another individual) in people with social anxiety disorder (SAD) compared…
- Trial name
- NCT05968651
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Washington
Social Anxiety Disorder
PH94B Nasal Spray for Anxiety Induced by a Public Speaking Challenge
This Phase 3 clinical trial is designed to evaluate the efficacy, safety, and tolerability of the acute administration of 3.2 µg of PH94B to relieve symptoms of anxiety in adult subjects with social anxiety disorder (SAD) during…
- Trial name
- Palisade-1 (NCT04754802)
- Testing
- PH94B Nasal Spray
- Where
- 21 sites in United States
- Volunteers
- 224 people
- Sponsor
- VistaGen Therapeutics, Inc.
Social Anxiety Disorder
12-Week Study of Pristiq (Desvenlafaxine) Social Anxiety Disorder
This study is designed to evaluate the efficacy and safety of Pristiq® in treatment of the symptoms of Generalized Social Anxiety Disorder (SAD).
- Trial name
- NCT01316302
- Testing
- Pristiq
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- The Medical Research Network
Social Anxiety Disorder
Efficacy of an Attention Guidance VR Intervention for Social Anxiety Disorder
Social anxiety disorder (SAD) is a prevalent mental health concern that impacts approximately 12% of the population. One mechanism thought to maintain SAD is avoidance of faces (i.e. avoidance of negative evaluative threat).
- Trial name
- NCT03683823
- Testing
- Attention guidance, Control intervention
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Texas at Austin
ANXIETY DISORDERS (or Anxiety and Phobic Neuroses)
Fast-Fail Trials in Mood and Anxiety Spectrum Disorders; Kappa Opioid Receptor Phase 2a
The available treatment for patients with mood and anxiety disorders have significant limitations (Rush, 2007; Denys and de Geus, 2005). There is a need to develop new treatments for people with these disorders.
- Trial name
- FASTMAS_Kor2 (NCT02218736)
- Testing
- CERC-501
- Where
- 6 sites in United States
- Volunteers
- 163 people
- Sponsor
- Duke University
Phobic Disorders, Anxiety
Use of an Antibiotic as an Enhancer for the Treatment of Social Phobia
This study examines whether an antibiotic, d-cycloserine (DCS), boosts the effectiveness of cognitive behavior therapy (CBT) for social anxiety.
- Conditions
- Phobic Disorders, Anxiety, Social Phobia
- Trial name
- NCT00128401
- Testing
- D-Cycloserine
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- National Institute of Mental Health (NIMH)
Social Anxiety Disorder
Hormones and Social Anxiety Disorder Treatment
The purpose of this study is to determine whether power posing (i.e., holding poses associated with dominance and power), compared to submissive posing or rest, prior to exposure therapy for social anxiety disorder: 1) leads to a…
- Trial name
- NCT02482805
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Jasper A. Smits
Phobia, Social
Internet Treatment for Social Phobia in Romania
The main aim of this study is to investigate the effectiveness of an Internet-delivered intervention for social phobia by comparing it to a waitlist control group.
- Trial name
- iSOFIE-Ro (NCT01557894)
- Testing
- iSOFIE
- Where
- Romania
- Volunteers
- 76 people
- Sponsor
- Babes-Bolyai University
Social Anxiety Disorder
Attention, Teleconferencing and Social Anxiety
This study involves completing some online assessments and an intervention for social anxiety that all involve interactions with other people on a teleconferencing call.
- Trial name
- NCT04729803
- Testing
- Experimental: Attention Guidance + Exposure, Active Comparator: Exposure Alone, Experimental: Attention Control + Exposure
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- University of Texas at Austin
Social Phobia
Social Phobia Intervention Study of Mannheim
Primary objective: The purpose of this study is to examine efficacy and efficiency of a Stepped Care Program (SCP) for patients with Social Phobia in comparison to the standard cognitive therapy for Social Phobia according to…
- Trial name
- NCT00434759
- Testing
- cognitive therapy, stepped care program based on cognitive therapy
- Where
- Germany
- Volunteers
- 89 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Social Anxiety Disorder
Effect of D-cycloserine Plus Cognitive Behavioral Therapy on People With Social Phobia
This study will assess the effectiveness of D-cycloserine combined with cognitive-behavior therapy in treating people with social anxiety disorder.
- Trial name
- NCT00515879
- Testing
- D-cycloserine, Cognitive behavioral therapy (CBT)
- Where
- United States
- Volunteers
- 169 people
- Sponsor
- Boston University Charles River Campus
Fear of Flying
Emotional Processes in VR Exposure Treatment for Flight Phobia
This study will assess emotional processes and their relation to treatment outcomes during Virtual reality exposure therapy for Flight Phobia.
- Trial name
- NCT04213859
- Testing
- VRET - Virtual Reality Exposure Therapy
- Where
- Israel
- Volunteers
- 84 people
- Sponsor
- Idan Moshe Aderka
Arachnophobia, Phobia
TMS and Exposure Therapy
Spider phobia is an exceedingly common phobia throughout the world. The current standard treatment involves exposure therapy, which consists of a series of brief exposures of an individual to the thing they fear, in this case…
- Trial name
- NCT04019054
- Testing
- Intermittent Theta Burst Stimulation (iTBS), Ventromedial Prefrontal Cortex (vmPFC), Intermittent Theta Burst Stimulation (iTBS), vertex
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of California, Los Angeles
Generalized Social Phobia
Efficacy and Tolerability of Atomoxetine (Strattera) in Adult Patients With Generalized Social Anxiety Disorder
The purpose of this study is to determine the effectiveness and tolerability of atomoxetine (Strattera) in adult patients with generalized social anxiety disorder (an anxiety disorder characterized by a fear of interpersonal…
- Trial name
- NCT00260533
- Testing
- atomoxetine
- Volunteers
- 27 people
- Sponsor
- University of California, San Diego
Generalized Anxiety Disorder, Separation Anxiety Disorder
Treatment of Pediatric Anxiety Disorders by Predicting Treatment Response Through Biocellular Markers and Sleep
1 out of 8 children, adolescents, and young adults suffer from an anxiety disorder. Studies over the past decade show that selective serotonin-reuptake inhibitors (SSRIs), a class of medication that treats anxiety in adults, also…
- Conditions
- Generalized Anxiety Disorder, Separation Anxiety Disorder, Social Phobia
- Trial name
- NCT02189213
- Testing
- Sertraline
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Claustrophobia, Complication of Diagnostic Procedure
Comfort Talk and Economic Outcomes in MRI
Annually, an estimated 700,000 patients do not complete their scheduled MRI scans because of claustrophobia or inability to hold still.
- Trial name
- ComfortTalk® (NCT02427737)
- Testing
- Comfort Talk® Training
- Where
- 3 sites in United States
- Volunteers
- 12 people
- Sponsor
- Hypnalgesics, LLC
Anxiety Disorders
Threat Interpretation Bias as Cognitive Marker and Treatment Target in Pediatric Anxiety
Anxiety is the most common mental health problem in children and adolescents. This two-phased study will test the effects of an experimental computerized intervention aimed at reducing threat-based thinking (i.e., interpretation…
- Trial name
- NCT04245501
- Testing
- Cognitive Bias Modification for Interpretations (CBM-I), Interpretation Control Condition (ICC)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Denver
Phobic Disorders
D-Cycloserine to Enhance Cognitive Behavioral Therapy (CBT) for Acrophobia
The purpose of this study is to investigate the utility of post-session administration of D-cycloserine to enhance fear extinction in a sample of people with acrophobia who will be treated with CBT.
- Trial name
- NCT01102803
- Testing
- Individual Cognitive Behavioral Therapy (CBT), D-Cycloserine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Southern Methodist University
Anxiety Disorder Social, Anxiety
A Study of the Efficacy of Botox in the Treatment of Social Anxiety Disorder
The goal of this study is to see whether Botox is an effective treatment for social anxiety disorder (SAD). Participants will complete two short surveys on depression and anxiety symptoms, receive a one-time injection of Botox…
- Trial name
- NCT03078270
- Testing
- botulinum toxin A
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Daniel Lieberman
Dental Anxiety
Efficacy of an Internet-based Intervention for Dental Anxiety
The overall objective of the activities described in this protocol is to examine the efficacy of the Internet-based intervention in the reduction of dental anxiety in patients seeking dental treatment.
- Trial name
- NCT03680755
- Testing
- Internet-based intervention for dental anxiety
- Where
- United States
- Volunteers
- 503 people
- Sponsor
- Temple University