Clinical trials: Photoaged Skin
Photoaged Skin, Normal Skin
Immunologic Profile of Chronically Photodamaged Skin
Chronically photodamaged skin is visually characterized by dryness, wrinkles, brown spots, leathery appearance, etc. This happens as a result of excessive exposure to UV light from the sun.
- Trial name
- NCT02889159
- Testing
- Candida albicans antigen, histamine phosphate, imiquimod 5% cream
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Aged Skin, Photoaged Skin
Retinol-induced Dermatitis in Aged Skin
Topical therapy with retinoids is the only proven medical therapy for aged/photoaged human skin. However, topical therapy with retinoids often result in unwanted cutaneous dermatitis, including erythema and scaling.
- Trial name
- NCT00857610
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Photo-aging, Keratosis
The Effect of Efudex Treatment on Photoaged Skin
The researchers propose that skin improvements may be seen following a course of Efudex, (5-fluorouracil), a FDA-approved topical therapy (applied directly to the skin).
- Trial name
- NCT00121511
- Testing
- Efudex (5-fluorouracil)
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Rhytides, Skin Texture Irregularities
Efficacy & Safety of hADM Skin Booster
The goal of this randomized, split-face, double-blinded clinical trial is to evaluate the efficacy and safety of Elravie Re2O (particulated human Acellular Dermal Matrix, phADM) as a skin booster compared with hyaluronic acid…
- Conditions
- Rhytides, Skin Texture Irregularities, Photoaged Facial Skin, Skin Lifting and Tightening
- Trial name
- NCT07155278
- Testing
- Elravie Re2O, Elravie Balance
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Yonsei University
Photoaged Skin
Comparison of Metvix Photodynamic Therapy (PDT) With Its Vehicle in the Treatment of Photoaged Skin
Skin photoaging or skin photodamage were terms used to describe the change in the structure, function and appearance of skin caused by prolonged and repeated exposure to sunlight or other ultraviolet light sources.
- Trial name
- NCT00437320
- Testing
- Metvix Cream 160 mg/g, Metvix Vehicle Group
- Where
- 3 sites in Spain, United Kingdom
- Volunteers
- 32 people
- Sponsor
- Galderma R&D
Photoaged Facial Skin, Photoaging
Study of RRS® HA Long Lasting for Improving Facial Wrinkles and Skin Quality
The objective of this clinical study is to confirm the clinical performance and long-term safety of the CE-marked RRS® HA Long Lasting in the treatment of skin photoaging and its consequences, with a primary focus on improving…
- Conditions
- Photoaged Facial Skin, Photoaging, Wrinkle Reduction, Skin Quality Improvement
- Trial name
- ORACLE LL (NCT07551609)
- Testing
- RRS® HA Long Lasting
- Where
- 6 sites in Spain
- Volunteers
- 207 people
- Sponsor
- Skin Tech Pharma Group S.L.U.
Chronic Effect of Ultraviolet Radiation on Photoaged Skin, Dermatologic Disorders
Safety Study of Bone Marrow Derived Stem Cells on Patients With Cutaneous Photoaging
The purpose of this study is to determine whether a one-time injection of allogeneic mesenchymal bone marrow cells is safe and beneficial in the treatment of photodamage on the face.
- Trial name
- NCT01771679
- Testing
- Allogeneic Mesenchymal Bone Marrow Cells
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Stemedica Cell Technologies, Inc.
Photoaging
The Effects of Zinc Di-(Dibutyryl Lisinate) on Skin Health and the Skin Microbiome in Photoaged Skin
This study is a double-blind randomized vehicle-controlled study assessing how Zinc Di-(dibutyryl lisinate) (Z-DBL) influences skin biophysical measures such as skin hydration, transepidermal water loss, and elasticity, as well…
- Trial name
- NCT06096649
- Testing
- Topical Vehicle + Zinc Di-(dibutyryl lisinate), Topical Vehicle
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Skin Aging, Hyperpigmentation
Homocysteic Acid Biostimulator for Photoaged Facial Skin
This study evaluated whether a chemical skin biostimulator containing ammonium trichloroacetate, homocysteic acid, phytic acid and citric acid can improve signs of photoaged skin in women with mature skin.
- Trial name
- NCT07722351
- Testing
- Chemical skin biostimulation with ammonium trichloroacetate and homocysteic acid
- Where
- Poland
- Volunteers
- 25 people
- Sponsor
- Medical University of Silesia
Photoaging
Efficacy in Daily Use of a Novel Skin Care Product for the Treatment of Photoaged Skin
Photoaged or chronically sun-exposed skin is characterised by a number of clinical features including fine and coarse wrinkles. The pathogenesis of wrinkle formation has yet to be determined fully but recent work suggests that…
- Trial name
- NCT03144193
- Testing
- Topical anti-aging cosmetic cream
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Photoaging
RFMN in Combination With 1927 nm Thulium Laser for Treating Photoaged Skin
The appearance of the aging skin is influenced by different factors including by the reduced elasticity and increased laxity of the skin, the decreasing volume as well as pigmentation disorders and dilated vascular markings.
- Trial name
- NCT06029725
- Testing
- radiofrequency microneedling combined with 1927 nm thulium laser, radiofrequency microneedling monotherapy
- Where
- Germany
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Aging Problems, Pigmentation
16-Week Randomized Split-Face Efficacy Study of Cosmetic Formulations in Photoaged Pigmented Skin Subjects
The objective of this study is to determine the efficacy of seven different formulations currently marketed and commercially available cosmetic products on skin tone evenness, post-inflammatory hyperpigmentation, and discrete…
- Trial name
- NCT05160103
- Testing
- Cosmetic Formulations
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Avon Products, Inc.
Actinic Keratosis, Photo-aged Skin
Clinical and Histologic Evaluation of Picato 0.15% Gel in the Cosmetic Improvement of Photoaged Skin
Clinical Evaluation: Subjects having actinic keratoses and meeting Glogau Photoaging Class III or IV complete the FDA approved 3 day course of Picato® 0.015% gel as approved for the treatment of facial Actinic Keratosis.
- Trial name
- NCT03508856
- Testing
- Ingenol Mebutate (Picato®) 0.015% gel
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Skin Laser & Surgery Specialists
Pigmentation, Pigmentation Disorder
A Prospective, Split-face, Randomized Study of the Poly-D, L Lactic Acid (PDLLA) for Photoaged Skin
Juvelook® (VAIM, Korea) is made by dissolving irregular PDLLA particles in a solvent mixture of DMSO (Dimethylsulfoxide) and EC (Ethylene Carbonate) and then injecting them through microneedling to create reticulated foamy…
- Trial name
- NCT05913102
- Testing
- PDLLA
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jin Cheol Kim
Photoaging
Effects of an Oral Herbal Supplement on Skin Aging, Hydration, and Elasticity
The purpose of this study is to evaluate how an oral herbal supplementation influences facial skin elasticity and facial hydration as well as markers of photoaging (erythema and pigmentation).
- Trial name
- NCT06146140
- Testing
- Oral herbal supplement
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Photoaged Facial Skin
VBeam Prima for Treatment of Photoaged Facial Skin
This is an open-label, single-center study. Subjects in this study will receive up to four (4) facial treatments at 4-6 (±1) weeks interval, with the VBeam Prima device according to the study protocol.
- Trial name
- NCT03383705
- Testing
- VBeam Prima
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Photoaging
Efficacy of Topical Antioxidants in Tretment of Photoaging
This randomized controlled trial study aims at investigating the efficacy and safety of topical antioxidants in treatment of a cohort of non-elderly volunteers with photoaged skin.
- Trial name
- NCT04835259
- Testing
- Selenium Amino Acid Chelate (Selenium ACE cream)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Photoaging
Effect of Platelet Rich Plasma on Photoaged Skin
The goal of this study is to assess the safety, tolerability and effectiveness of platelet rich plasma in the treatment of photoaged skin. This study will be divided into two parts.
- Trial name
- NCT01372566
- Testing
- Harvest PRP Separation System, Sterile Saline injection
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Northwestern University