Clinical trials: Photoaging
Photoaging
Xeomin, Radiesse, and Belotero Facial/Neck Rejuvenational
The purpose of this study is to determine the improvement in signs of photoaging and subject satisfaction after combination, global facial and/or neck treatment with IncobotulinumA (Xeomin), HA (Belotero) and/or calcium…
- Trial name
- NCT05039723
- Testing
- Radiesse, Xeomin, Belotero
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Main Line Center for Laser Surgery
Fine Lines, Wrinkles
A Clinical Study to Evaluate Efficacy and Safety of a Cosmetic Product in the Treatment of Facial Lines
This randomized, double-blind, placebo-controlled clinical trial was conducted to assess the efficacy and safety of an anti-aging serum to improve the appearance of expression lines as well as overall skin health of aging skin…
- Conditions
- Fine Lines, Wrinkles, Photoaging
- Trial name
- NCT04545970
- Testing
- Facial cleanser, Facial moisturizer, Sunscreen
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Sun-Damaged Skin, Retinoid Intolerance
The Effect Of A Controlled Daily Skin Care Regimen On Retinoic Acid Tolerance
Sun-damaged skin, caused by chronic exposure to ultraviolet (UV) light, is characterized by features such as wrinkling, uneven skin color, roughness and brown spots.
- Trial name
- NCT00440024
- Testing
- Tazorac, Dove Mild Cleanser, Dove Facial Moisturizer
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Sun Damaged Skin
Photoprotective Effects of a SPF50+ Sunscreen on Skin Genotoxicity Induced by Repeated Chronic Outdoor Sun Exposure
Between 2 and 3 million non-melanoma skin cancers and 132,000 melanoma skin cancers occur globally each year. Sun protection continues to be a major public health issue and has always been a priority research area for Pierre…
- Trial name
- NCT05926791
- Testing
- Cosmetic product
- Where
- France
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Dermo Cosmetique
Sun Damaged Skin
Efficacy Evaluation of Products Against Long Wavelength Ultraviolet A1 and Visible Light Induced Biological Effects
The purpose of this study is to evaluate the efficacy of topical products in providing protection against the visible light and ultraviolet A1 (UVA1) part of sunlight.
- Trial name
- NCT04181476
- Testing
- Sunscreening Agents
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Photoaging
The Efficacy and Safety of a Single 70% Glycolic Acid Peel With Vitamin C for the Treatment of Photoaging
Our study involves the evaluation of a high potency peel in its efficacy for skin rejuvenation in the treatment of photoaging. This chemical peel regime is a high potency peel 70% glycolic acid combined with vitamin C that is…
- Trial name
- NCT02126644
- Testing
- 70% glycolic acid
- Where
- Singapore
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Skin Aging, Sun Damaged Skin
The Effects of an LED Face Mask & Neck and Chest Mask On Skin Health
This 12-week single-group virtual study evaluates the effects of the iRESTORE Illumina LED Face Mask and Neck \& Chest Mask on skin health in adult females.
- Trial name
- NCT07025837
- Testing
- iRESTORE Illumina LED Face Mask and Neck & Chest Mask
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Freedom Laser, Inc.
Erythema, Sun Damaged Skin
Efficacy Study of a Novel Skin Health Product to Reduce an UVB Induced Erythema
The aim of this study is to determine the erythema-reducing efficacy of a test product in two concentrations on a light sunburn induced by a sun simulator compared to an untreated control and a placebo product.
- Conditions
- Erythema, Sun Damaged Skin, Skin Inflammation
- Trial name
- NCT05300542
- Testing
- Topical Cream with 0.5% Active, Topical Cream with 1% Active
- Where
- Germany
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Photodamaged Skin, Photoaging
Altreno for Chest Rejuvenation
This is a single-center, prospective, double-blind, randomized, vehicle-controlled study to evaluate the efficacy, safety and patient satisfaction of tretinoin 0.05% lotion (Altreno) for chest rejuvenation.
- Trial name
- NCT04096742
- Testing
- tretinoin 0.05% lotion (Altreno), Vehicle
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Photoaging, Wrinkle
A Clinical Study to Evaluate the Long-Term Efficacy and Tolerability of a Daily Anti-Aging Daily Serum
This double-blind, randomized, placebo-controlled, single-center clinical trial was conducted to assess the efficacy and tolerance of an anti-aging daily serum to improve moderate overall photodamage and skin fatigue after…
- Trial name
- NCT05514782
- Testing
- Cleansing Lotion, Facial Moisturizer, Sunscreen SPF 40+
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Tobacco Addiction, Smoking Related Diseases
A Photoaging Mobile App Promoting Poster Campaign for Preventing Smoking in Secondary Schools
The purpose of this study is to determine whether photoaging mobile app promoting poster campaigns are effective to reduce smoking prevalence among adolescents in Germany. This is measured via questionnaire.
- Conditions
- Tobacco Addiction, Smoking Related Diseases, Adolescent Smoking
- Trial name
- Smokerface (NCT02544360)
- Testing
- Photoaging mobile app promoting poster campaign.
- Where
- Germany
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- University of Giessen
Sun Damaged Skin
An Assessment of TLR4 and TOPK/PRPK Signaling in Sun Damaged Human Skin Acutely Exposed to Solar Simulated Light
The purpose of this project is to obtain clinical data, including skin samples, that will help investigators evaluate changes occurring in sun damaged human skin as a result of light that simulates sun exposure (Solar Simulated…
- Trial name
- NCT05398237
- Testing
- Solar Simulated Light (SSL)
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Photo-aging, Keratosis
The Effect of Efudex Treatment on Photoaged Skin
The researchers propose that skin improvements may be seen following a course of Efudex, (5-fluorouracil), a FDA-approved topical therapy (applied directly to the skin).
- Trial name
- NCT00121511
- Testing
- Efudex (5-fluorouracil)
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Intrinsic Aging of Skin, Solar Elastosis
Onabotulinum Toxin Type A and Abobotulinum Toxin Type A Crow's Feet Rhytid Study
The objective of the study is to compare the time to onset of Dysport® versus Botox® in the treatment of lateral orbital rhytids ("crow's feet").
- Trial name
- NCT01529788
- Testing
- Right lateral orbital injection of Botox Cosmetic or Dysport, Left lateral orbital injection of Botox Cosmetic or Dysport
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The Maas Clinic
Photodamage, Photoaging
Efficacy and Safety of Oral Isotretinoin for Cutaneous Photodamage
This is a randomized, comparative, single evaluator-blinded trial to evaluate clinical, histological and immunohistochemical effects of oral isotretinoin plus moisturizer sunscreen as compared to the use of 0,05% tretinoin cream…
- Trial name
- NCT00842907
- Testing
- oral isotretinoin, Tretinoin
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Skin Photoaging
Efficacy and Tolerance Evaluation of an Amino Acid Food Supplement
Skin moisturizing and elasticizing efficacy of an amino acid food supplement
- Trial name
- NCT03801343
- Testing
- Nutrakos®
- Where
- Italy
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Derming SRL
Skin Cancer
The Effect of Green Tea and Vitamin C on Skin Health
There is little information on the effect of oral bioactive compounds on human skin clinically despite evidence of a beneficial effect from laboratory studies.
- Trial name
- NCT01032031
- Testing
- Green tea + vitamin C high dose
- Where
- United Kingdom
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Photoaging, Hyperpigmentation
Randomized, Double-Blind Evaluation of Maple Leaf Extract (Maplifa) for Photoaging
Recent research has reported that the maple leaf extract exhibits anti-aging effects by inhibiting elastase activity, thereby preventing the breakdown of elastin and interfering with the formation of wrinkles.
- Conditions
- Photoaging, Hyperpigmentation, Rhytides
- Trial name
- NCT04586816
- Testing
- 1% red maple leaf extract in cream base, 5% red maple leaf extract, vehicle
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Cutaneous Photoaging
Efficacy and Safety of Kinetin 0.1% for Treatment of Skin Photoaging
The purpose of the study is to evaluate the change in the severity and clinical signs of skin photoaging among Filipino patients using Kinerase cream (Kinetin 0.1%).
- Trial name
- NCT01898182
- Testing
- Kinetin, N6-furfuryladenine, 0.1%
- Where
- 2 sites in Philippines
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Makati Medical Center
Sunburn, Sun Damaged Skin
Natural Sunlight Protection and Simulated Sunlight Protection Offered by Sunscreens and Fabrics
The purpose of this study is to assess how human skin reacts and how sunscreens and sun protection fabrics protect in natural sunlight compared to their labeled claims, indoor testing methods (existing or modified) and…
- Conditions
- Sunburn, Sun Damaged Skin, Overexposure to Sun Rays
- Trial name
- NCT03007589
- Testing
- otc sunscreens, sun protection fabrics, Optical Filters
- Where
- 5 sites in United States, Chile and 1 more
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sun Protection Foundation