Clinical trials: Photoaging
Photoaging, Wrinkle
Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With a Radiofrequency Microneedling for Facial Rejuvenation
This randomized, single-center, double-blinded, controlled, clinical trial was conducted to investigate the tolerability, safety, and efficacy of a post-procedure cream when used immediately after radiofrequency microneedling and…
- Trial name
- NCT06157853
- Testing
- Radiofrequency Microneedling, Facial Cleanser, Facial Moisturizer
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Photoaging
Xeomin, Radiesse, and Belotero Facial/Neck Rejuvenational
The purpose of this study is to determine the improvement in signs of photoaging and subject satisfaction after combination, global facial and/or neck treatment with IncobotulinumA (Xeomin), HA (Belotero) and/or calcium…
- Trial name
- NCT05039723
- Testing
- Radiesse, Xeomin, Belotero
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Main Line Center for Laser Surgery
Photoaging
Effect of Platelet Rich Plasma on Photoaged Skin
The goal of this study is to assess the safety, tolerability and effectiveness of platelet rich plasma in the treatment of photoaged skin. This study will be divided into two parts.
- Trial name
- NCT01372566
- Testing
- Harvest PRP Separation System, Sterile Saline injection
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Moderate-severe Skin Aging/Photoaging
Efficacy and Tolerance Evaluation of an Anti-age Food Supplement
Efficacy and Tolerance Evaluation of an Anti-age Food Supplement: a Randomized, Controlled Clinical Study Versus Untreated Group
- Trial name
- NCT03274154
- Testing
- Pre-Hyaluron 465 Innēov
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Derming SRL
Photodamage, Photoaging
Efficacy and Safety of Oral Isotretinoin for Cutaneous Photodamage
This is a randomized, comparative, single evaluator-blinded trial to evaluate clinical, histological and immunohistochemical effects of oral isotretinoin plus moisturizer sunscreen as compared to the use of 0,05% tretinoin cream…
- Trial name
- NCT00842907
- Testing
- oral isotretinoin, Tretinoin
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Intrinsic Aging of Skin, Solar Elastosis
Onabotulinum Toxin Type A and Abobotulinum Toxin Type A Crow's Feet Rhytid Study
The objective of the study is to compare the time to onset of Dysport® versus Botox® in the treatment of lateral orbital rhytids ("crow's feet").
- Trial name
- NCT01529788
- Testing
- Right lateral orbital injection of Botox Cosmetic or Dysport, Left lateral orbital injection of Botox Cosmetic or Dysport
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The Maas Clinic
Sun Damaged Skin
Singlet Oxygen Quantification After Skin Exposure to Ultraviolet A (UVA) Light
The objective of this study is quantification of singlet oxygen species in the skin after exposure to Ultraviolet A (UVA) light
- Trial name
- NCT05865431
- Testing
- Zinc Oxide and Avobenzone
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Photoaging, Skin Aging
AI-Personalized Skincare Regimen for Facial Photoaging in Women
The goal of this clinical study was to learn whether a skincare regimen personalized by an artificial intelligence (AI) skin-analysis tool improves signs of facial skin aging in women aged 35 to 65 with mild-to-moderate facial…
- Trial name
- NCT07879833
- Testing
- AI-personalized skin longevity regimen
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- MDalgorithms Inc.
Photoaging
Effects of an Oral Herbal Supplement on Skin Aging, Hydration, and Elasticity
The purpose of this study is to evaluate how an oral herbal supplementation influences facial skin elasticity and facial hydration as well as markers of photoaging (erythema and pigmentation).
- Trial name
- NCT06146140
- Testing
- Oral herbal supplement
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Chronic Effect of Ultraviolet Radiation on Photoaged Skin, Dermatologic Disorders
Safety Study of Bone Marrow Derived Stem Cells on Patients With Cutaneous Photoaging
The purpose of this study is to determine whether a one-time injection of allogeneic mesenchymal bone marrow cells is safe and beneficial in the treatment of photodamage on the face.
- Trial name
- NCT01771679
- Testing
- Allogeneic Mesenchymal Bone Marrow Cells
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Stemedica Cell Technologies, Inc.
Photoaging, Weight Loss
Evaluation of the Effects of a Biostimulator and Dermal Fillers for Cheek Augmentation and Contour Deficiencies
Adult subjects with a history of or currently taking glucagon-like peptide-1 (GLP-1) receptor agonist medication and moderate-to-severe cheek wrinkles and midface contour deficiencies will be treated with Sculptra correction of…
- Conditions
- Photoaging, Weight Loss, Skin Laxity, Photodamaged Skin
- Trial name
- NCT06351358
- Testing
- Sculptra treatment, Restylane Treatment
- Where
- 2 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Photoaging, Wrinkle
Same-Day Combination of VI Peel and Botox for Correction of Sun Damage, Fine Lines and Wrinkles
This study is being conducted to improve standards of care in the cosmetic treatment of sun damage, fine lines, and wrinkles. VI Peels® and Botox® have been used cosmetically to improve patient concerns as monotherapies.
- Conditions
- Photoaging, Wrinkle, Sun Damaged Skin
- Trial name
- NCT05162300
- Testing
- Same Day Intervention of VI Peel (Procedure) and Botulinum Toxin (Drug)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Vitality Institute Medical Products
Photoaging
Trial Evaluating Both Tolerability and Improvement for Signs of Facial Photoaging, Discoloration, and Texture in Adult Females of All Skin Types by Combining a Placebo Moisturizer and Non-ablative Laser.
This is a phase 4 trial evaluating the clinical effect of combining a placebo moisturizer and non-ablative laser to improve procedural outcomes in patients with facial dyschromia.
- Trial name
- NCT06090071
- Testing
- LaseMD Laser, Sciton Laser, Phyto A+ Brightening Treatment
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Austin Institute for Clinical Research
Skin Aging, Photoaging of Skin
Clinical Evaluation of Day and Night Skin Care Creams Supplemented With MediCell Technology (MCT)'s Composition of Defensins and Supportive Molecules
This is a placebo-controlled blinded clinical evaluation of day and night skin care creams supplemented by Medicell Technology's composition of defensins and supportive molecules determine the skin hydration and anti-aging…
- Trial name
- NCT02765763
- Testing
- 2-Minute Reveal Masque, 24/7 Barrier Repair Cream, 8-in-1 BioSerum
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Advanced Dermatology
Skin Cancer
Sunface Mirroring RCT in Brazil
Randomized trial looking at the effects of a behavioral photoaging software intervention on sunscreen use in the city of Itauna, Brazil.
- Trial name
- NCT03178240
- Testing
- photoaging mirroring intervention
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Giessen
Healthy Skin, Skin Wrinkling
The Effects of Microdermabrasion on Skin Remodeling
This research project aims to study the effects of microdermabrasion, a technique causing minimal injury used to improve the appearance of fine lines, wrinkles, and scars.
- Trial name
- NCT00111254
- Testing
- Microdermabrasion
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Cardiovascular Risk Factor, Metabolic Disease
Effects of Shockwave Therapy Versus Radiofrequency
The main objective of this study is to compare the effect of 6 sessions of shock wave therapy versus radiofrequency followed by a protocol of moderate aerobic exercise, in the reduction of adiposity and abdominal flaccidity, in…
- Conditions
- Cardiovascular Risk Factor, Metabolic Disease, Photoaging
- Trial name
- NCT04282057
- Testing
- Radiofrequency, Aerobic exercise, Shock wave therapy
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Escola Superior de Tecnologia da Saúde do Porto
Photoaging
Platelet Rich Fibrin Versus Platelet Rich Plasma for Microneedling Treatment of Facial Photoaging
The present study was conducted for analyzing the efficacy and safety of platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) in photoaging therapy. Specific arms: 1.
- Trial name
- NCT06452667
- Testing
- platelet-rich fibin, platelet-rich palsma
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Wrinkle, Photoaging
An Exploratory Investigation of a Novel Skincare Regimen
This trial will assess the effectiveness of the Aria Trio Complete Facial system in being able to reduce blemishes, lines, and wrinkles.
- Conditions
- Wrinkle, Photoaging, Acne, Skin Inflammation
- Trial name
- NCT05517720
- Testing
- Aria Trio complete Facial System
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Trophy Skin
Photoaging, Wrinkle
Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With a Hybrid-Fractional Laser for Facial Rejuvenation
This randomized, multi-center, double-blinded, split-face, controlled clinical trial was conducted to investigate the tolerability, safety, and efficacy of a post-procedure cream when used immediately after hybrid-fractional…
- Conditions
- Photoaging, Wrinkle, Skin Laxity
- Trial name
- NCT06436261
- Testing
- Hybrid Fractional Laser, Facial Cleanser, Facial Moisturizer
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Revision Skincare