Clinical trials: Photobiomodulation, open to volunteers
Chronic Fatigue Syndrome (CFS), Quality of Life
Photobiomodulation in Chronic Fatigue Syndrome
The goal of this clinical trial is to evaluate whether photobiomodulation therapy (low-level laser therapy) can reduce fatigue and improve quality of life in patients with chronic fatigue syndrome (CFS).
- Trial name
- NCT07546539
- Testing
- Photobiomodulation (Low-Level Laser Therapy)
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- University of Lahore
Oral Mucositis Due to Chemotherapy, Hematolymphoid Malignancies
Phase II Single Arm Open Label Study Evaluating the Feasibility and Safety of Photobiomodulation as an Adjunct to Standard Supportive Care for Chemotherapy Induced Oral Mucositis in Pediatric Patients With Hematolymphoid Malignancies
Chemotherapy induced oral mucositis is a common and debilitating complication in pediatric patients receiving chemotherapy for hematolymphoid malignancies.
- Trial name
- BEAM (NCT07605234)
- Testing
- Photobiomodulation Therapy
- Volunteers
- 46 people
- Sponsor
- Tata Memorial Hospital
Stroke, Spasticity
The Use of Photobiomodulation in the Treatment of Spasticity After Stroke.
Stroke is a non-progressive and permanent syndrome in adults, with approximately 60% of patients presenting with spastic hemiparesis.
- Conditions
- Stroke, Spasticity, Photobiomodulation, NIRS
- Trial name
- DarbarIllora (NCT07784231)
- Testing
- Photobiomodulation Therapy, Standard Multidisciplinary Rehabilitation Program for Spasticity
- Where
- Brazil
- Volunteers
- 42 people
- Sponsor
- University of Nove de Julho
Radiotherapy Side Effect, Vaginal Abnormality
Photobiomodulation Therapy in the Prevention and Management of Radiotherapy-induced Vaginal Toxicity
This study aims to investigate the effectiveness of photobiomodulation therapy (PBMT) in the prevention and management of radiotherapy-induced vaginal toxicity (RIVT).
- Trial name
- GynLight (NCT05165056)
- Testing
- Intimleds
- Where
- 2 sites in Belgium
- Volunteers
- 62 people
- Sponsor
- Jessa Hospital
Symptoms of Anxiety
Transcranial Photobiomodulation in Anxiety Disorders
The investigators have previously shown that safe, non-invasive methods of brain stimulation such as the administration of transcranial infrared light can result in improvements to cognition and emotion.
- Trial name
- NCT07133893
- Testing
- Attention bias assessment and modification, Transcranial photobiomodulation
- Where
- United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Francisco Gonzalez-Lima, PhD
Aphthous Ulcer
Effects of Photobiomodulation (PBM) on Pain After Presentation of Aphthous Ulcers in Pediatric Dental Patients
The purpose of this study is to compare the efficacy of laser photobiomodulation and "Magic Mouthwash" for treatment of pain in pediatric patients with aphthous ulcers , to assess how photobiomodulation influences the rate of…
- Trial name
- NCT06819033
- Testing
- PBM Therapy, Maalox plus Benadryl
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The University of Texas Health Science Center, Houston
Bell's Palsy
Effects of Photobiomodulation and Electrical Stimulation Among Bell's Palsy Patients
Despite promising evidence supporting both photobiomodulation (PBM) and electrical stimulation (ES) in Bell's palsy rehabilitation, key gaps remain in the literature.
- Trial name
- NCT07266636
- Testing
- Photobiomodulation alongwith facial exercise, Electrical Stimulation alongwith facial exercise
- Volunteers
- 34 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Infraorbital Nerve Injury, Inferior Alveolar Nerve Injury
Nd:YAG Laser Photobiomodulation for Neurosensory Recovery Following Bimaxillary Orthognathic Surgery
This study investigates whether low-energy laser light therapy applied to the skin (photobiomodulation, PBM) can speed up recovery of sensation in the lower lip, chin, and cheek area following jaw surgery (bimaxillary…
- Conditions
- Infraorbital Nerve Injury, Inferior Alveolar Nerve Injury, Neurosensory Disturbance Following Orthognathic Surgery, Photobiomodulation
- Trial name
- NCT07789821
- Testing
- Nd:YAG laser photobiomodulation
- Volunteers
- 36 people
- Sponsor
- National University Hospital, Singapore
Chemotherapy-induced Peripheral Neuropathy
Photobiomodulation Therapy in the Management of Chemotherapy-Induced Peripheral Neuropathy
This study aims to investigate the effectiveness of photobiomodulation therapy (PBM) in the management of chemotherapy-induced peripheral neuropathy (CIPN).
- Trial name
- NeuroLight 2 (NCT05763706)
- Testing
- Multiwave Locked System® (M6 laser, ASA srl, Arcugnano (VI), Italy)
- Where
- Belgium
- Volunteers
- 172 people
- Sponsor
- Jessa Hospital
Orthodontic Tooth Movement
Acceleration of Tooth Movement Using PRP and Photobiomodulation With Clear Aligners
This study compares the effectiveness of two adjunct therapies- photobiomodulation (low-level laser therapy) (PBM) and localized platelet-rich plasma (PRP) injections in accelerating orthodontic tooth movement.
- Trial name
- NCT07795073
- Testing
- Platelet Rich Plasma (PRP) injection, photobiomodulation (PBM) Therapy, clear aligner(12-hour wear protocol)
- Where
- Yemen
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sana'a University
Postoperative Facial Ecchymosis, Postoperative Facial Edema
Perioperative Photobiomodulation in Facial Plastic Surgery
This study is testing whether a new light therapy schedule can reduce bruising after facial plastic surgery, compared with the light therapy schedule currently used in the investigator's practice.
- Trial name
- CLEAR PBM (NCT07846631)
- Testing
- ELIXIR MD Photobiomodulation (PBM) System
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Elixir MD Inc
Inflammation, Osteoarthritis
Photobiomodulation Therapy in Patients Receiving Total Knee Arthroplasty
Photobiomdoulation is the use of near-infrared light to relieve pain, stimulate healing and reduce inflammation. Swelling and inflammation is a common condition after orthopedics surgeries over extremity and spine.
- Conditions
- Inflammation, Osteoarthritis, Post Operative Pain
- Trial name
- NCT06426251
- Testing
- Photobiomodulation
- Where
- Taiwan
- Volunteers
- 15 people
- Sponsor
- National Taiwan University Hospital Hsin-Chu Branch
Healthy Volunteers (HV), Transcranial Photobiomodulation
Frequency-Dependent Effects of Transcranial Photobiomodulation on Cortical Excitability
This study aims to investigate the frequency-dependent effects of near-infrared (NIR) transcranial photobiomodulation (tPBM) on human cortical excitability and fine motor performance.
- Conditions
- Healthy Volunteers (HV), Transcranial Photobiomodulation, Cortical Excitability
- Trial name
- NCT07707284
- Testing
- Transcranial Photobiomodulation
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Ankle Dorsiflexion
Red Light Therapy: a Potential Strategy to Reduce Sports Injury Risk?
This study investigates whether near-infrared light therapy can acutely improve ankle dorsiflexion mobility and hamstring flexibility, two factors associated with sports injury risk.
- Trial name
- DIAERESIS (NCT07477678)
- Testing
- Near-infrared photobiomodulation, Cycling Warm-up
- Where
- Portugal
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cláudio da Silva Ferreira
Oral Mucositis
A Study to Describe the Effect of Photobiomodulation (Low Level Laser Therapy) in Reducing the Severity and Incidence of Oral Mucositis (Oral Ulceration) in Oral Cancer Patients Undergoing Radiation Treatment
The goal of this study is to describe the effect of photobiomodulation (PBM) on the incidence and severity of oral mucositis in post-operative oral cancer patients receiving radiotherapy +/- chemotherapy.
- Trial name
- PBM (NCT07387978)
- Testing
- photobiomodulation
- Where
- Australia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peter MacCallum Cancer Centre, Australia
Dry Eye Syndromes, Meibomian Gland Dysfunction
Photobiomodulation With REd vs BluE Light (REBEL)
The use of photobiomodulation or low-level light therapy (LLLT) in the ophthalmic field stemmed from dermatology which has shown impact on skin blood flow and regeneration.
- Conditions
- Dry Eye Syndromes, Meibomian Gland Dysfunction, Blepharitis
- Trial name
- NCT06371300
- Testing
- Red LLLT, Blue LLLT
- Where
- 2 sites in New Zealand, United Kingdom
- Volunteers
- 36 people
- Sponsor
- Aston University
Elderly Depression, Sleep Disturbance
Wearable-Based Study of Depression and Sleep in Older Adults
This 4-year study aims to develop a safe and effective management model for late-life depression using wearable technologies. The research will recruit older adults (aged 60 and above) with major depressive disorder, confirmed by…
- Trial name
- NCT07232472
- Testing
- Photobiomodulation
- Where
- United Kingdom
- Volunteers
- 162 people
- Sponsor
- China Medical University Hospital
Athletic Performance, Muscle Fatigue
Whole-Body Photobiomodulation Use in Professional Soccer Players During a State Championship
This study aims to investigate the effects of whole-body photobiomodulation on professional soccer players during a state championship.
- Conditions
- Athletic Performance, Muscle Fatigue, Muscle Strength, Sports
- Trial name
- WBPBM-PSC (NCT07224646)
- Testing
- Whole-Body Photobiomodulation (PBM) (Active PBM)
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Rhinoplasty, Edema
Effects of Red and Infrared Photobiomodulation in Rhinoplasty at a Single Centre
This single-centre, randomized, double-blind, sham-controlled clinical trial evaluates whether preoperative photobiomodulation (PBM) with red and infrared light can reduce early postoperative periorbital edema in patients…
- Trial name
- NCT07033039
- Testing
- Photobiomodulation, Simulation of Photobiomodulation, Standard treatment protocol
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Temporomandibular Disorders
Three Photobiomodulation Wavelengths (635, 940, and 1064 nm) on Chronic Myogenic Temporomandibular Disorder
Temporomandibular disorders (TMDs) are among the most common musculoskeletal conditions associated with chronic orofacial pain and functional disability.
- Trial name
- NCT07626164
- Testing
- 635 nm red diode laser, 940 nm NIR diode laser (Biolase), 1064 nm Nd:YAG laser (Fotona)
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Alexandria University