Clinical trials: Photodamage
Skin Ageing, Skin
Skin Type Determination Using Image Artificial Intelligence
Skin color, how easily a person burns or tans in the sun (skin phototype), and the amount of chronic sun damage in the skin are important factors in skin health.
- Trial name
- SPAI (NCT07765303)
- Testing
- Skin imaging and skin characteristic assessment
- Where
- 13 sites in Australia, Brazil and 9 more
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Region Skane
Rosacea, Acne Vulgaris
The Role of Topically Dissolved Oxygen (TDO) to Ameliorate Signs of Photodamage
This study is an evaluation of the role of topical dissolved oxygen to lessen visible signs of photodamage using a select regimen of topical dissolved oxygen containing cosmeceutical products.
- Conditions
- Rosacea, Acne Vulgaris, Atopic Dermatitis, Seborrheic Dermatitis
- Trial name
- NCT00991198
- Testing
- Topical oxygen
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Aria Aesthetics Inc.
Skin Manifestations
Tolerability and Efficacy of Anti-Aging Treatment Regimen in Subjects With Photodamage
The subjects will use the test skincare products. This is a full face, twice daily application study, with digital photos and expert grader evaluations at Baseline, 4 and 8 week periods.
- Trial name
- NCT02422836
- Testing
- Three Product Anti-Aging Treatment Regimen
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- US CosmeceuTechs, LLC
Skin Care
Study to Assess the Cosmetic Changes in the Facial Skin After Use of a Topical Retinoid Product in Participants With Moderate to Severe Photodamage
This study will assess the cosmetic changes of a cosmetic topical retinoid product in participants with moderate to severe photodamage utilizing non-invasive in vivo skin imaging instrumentation.
- Trial name
- NCT03302559
- Testing
- Retinol Complex 0.5, Facial cleanser, Moisturizing lotion
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Allergan
Wrinkle
Evaluating the Safety and Effectiveness of the Tixel Fractional System in the Treatment of Photodamage at Low Settings
To demonstrate the safety and performance of the Tixel fractional system for treatment of photodamage using low-energy settings.
- Trial name
- NCT05182502
- Testing
- Tixel
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Eric Bernstein, MD
Facial Photodamage
Study to Evaluate Efficacy and Tolerability of Two Topical Regimens in Subjects With Moderate to Severe Facial Photodamage Who Have Received Cosmetic Injections
This study will assess the efficacy and tolerability of two topical regimens (containing cosmetic human fibroblast-derived, physiologically-balanced growth factor combination products (HULK and TNS Essential Serum)
- Trial name
- NCT03559972
- Testing
- on-label facial injection
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Allergan
Skin Roughness, Mottling
Efficacy and Safety Study of Kinerase® for Treatment of Cutaneous Facial Photodamage
The purpose of the K.I.S.S. study is to evaluate the efficacy of Kinerase® Cream (Kinetin 0.1%) in Thai patients, on the basis of the severity and clinical signs of facial photodamage.
- Conditions
- Skin Roughness, Mottling, Blotchiness, Pigmentation
- Trial name
- NCT01885091
- Testing
- Kinerase
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Menarini (Thailand) Limited
Photodamage
Single Band vs. Dual Band Pulsed Light Technology for the Treatment of Photodamage - A Split Face Comparison Study
Both the Dye - VL 500 - 600 nm and the Dual band will improve significantly the appearance of Photo Damage with high efficacy including; safety, minimal discomfort and downtime.
- Trial name
- NCT04519736
- Testing
- Single Band vs. Dual Band Pulsed Light Technology for the Treatment of Photodamage
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Alma Lasers Inc.
Photodamaged Skin, Wrinkles
Comparison of Retinol 1.0% and Tretinoin 0.02% in the Treatment of Moderate to Severe Photodamage and Wrinkles
The purpose of this study is to assess the comparative efficacy of retinol 1.0% and tretinoin 0.02% in minimizing wrinkles, discoloration, roughness, and other signs of moderate to severe photodamage.
- Trial name
- NCT01283464
- Testing
- Retinol, Tretinoin
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Johns Hopkins University
Anti-aging, Photoaging
A Twelve Week Clinical Study to Evaluate the Efficacy and Tolerability of a Sunscreen Moisturizer SPF 50+
The primary objective of this study is to evaluate the efficacy and tolerance of a moisturizer SPF 50+ when used over a 12-week time period by women with moderate to severe facial photodamage.
- Trial name
- NCT06148558
- Testing
- Sunscreen Moisturizer, Gentle Cleansing Lotion, Facial Moisturizer
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Photodamage, Irregular Pigmentation
Comparison of the RevLite Electro-optic Q-Switched Neodymium-doped Yttrium Aluminium Garnet (EO QS Nd:YAG) Laser to a Fractionated Laser System
The purpose of this study is to compare the results of treatment between the side of the face treated with the RevLite Laser and the side of the face treated with a fractionated laser system.
- Conditions
- Photodamage, Irregular Pigmentation, Acne Scars
- Trial name
- NCT00955461
- Testing
- RevLite laser treatment, Fractionated Laser treatment
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- ConBio, a Cynosure Company
Photoaging
Adapalene Gel 0.3% Versus Tretinoin 0.05% Emollient Cream for Treatment of Photodamage
The primary purpose of this study is to compare the efficacy of adapalene (Differin®) gel 0.3% and tretinoin 0.05% emollient cream for the treatment of signs of photodamage, with tolerability assessment as a secondary objective.
- Trial name
- NCT00647556
- Testing
- adapalene gel, 0.3%, tretinoin 0.05% emollient cream
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Galderma R&D
Photodamaged Skin
Placebo-Controlled Study Assessing the Use of a Novel Exfoliative Serum With A Chemical Peel to Improve Photodamage in Adults
This is a split-face, double-blind, placebo-controlled study assessing the use of a novel exfoliative serum with a chemical peel to improve photodamage in healthy female subjects between the ages of 30 and 65 years, inclusive…
- Trial name
- NCT05908825
- Testing
- Vitamin C with AHA Exfoliative Serum
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Austin Institute for Clinical Research
Non-melanoma Skin Cancer
Dietary Prevention of Photodamage in Skin With Grapes
To assess the effect of orally administered grape powder on the sunburn reaction in humans.
- Trial name
- NCT02760160
- Testing
- Reconstituted grape powder
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Hyperpigmentation, Melasma
Annurca Apple Peel Oleolite for the Treatment of Skin Hyperpigmentation
The aim of this cosmetic clinical trial is to learn if an oleolite derived from Annurca Apple peel (AAO) works to enhance skin tone and luminosity, by counteracting the visibility of skin hyperpigmentation and dark spots in adult…
- Conditions
- Hyperpigmentation, Melasma, Skin Spots, Photodamaged Skin
- Trial name
- EAAO22G01 (NCT07040345)
- Testing
- Annurca apple oleolite
- Where
- Italy
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ritamaria Di Lorenzo
Facial Photodamage
Efficacy of Methyl Aminolevulinate + Daylight in Patients With Facial Photodamage
Treatment of actinic damage has included multiple procedures but to date there is limited scientific evidence to support the preferential use of one of these therapies according to their efficacy, safety and pain tolerance by…
- Trial name
- NCT02139618
- Testing
- Methyl Aminolevulinate (MAL)
- Where
- Colombia
- Volunteers
- 60 people
- Sponsor
- Fundación Dermabase
Photodamaged Skin, Photoaging
Altreno for Chest Rejuvenation
This is a single-center, prospective, double-blind, randomized, vehicle-controlled study to evaluate the efficacy, safety and patient satisfaction of tretinoin 0.05% lotion (Altreno) for chest rejuvenation.
- Trial name
- NCT04096742
- Testing
- tretinoin 0.05% lotion (Altreno), Vehicle
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Photodamage, Photoaging
Efficacy and Safety of Oral Isotretinoin for Cutaneous Photodamage
This is a randomized, comparative, single evaluator-blinded trial to evaluate clinical, histological and immunohistochemical effects of oral isotretinoin plus moisturizer sunscreen as compared to the use of 0,05% tretinoin cream…
- Trial name
- NCT00842907
- Testing
- oral isotretinoin, Tretinoin
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Photoaging, Photodamage
A Comparative Study of Adapalene Gel,0.3% Versus Tretinoin Emollient Cream, 0.05% for the Treatment of Photoaging
The purpose of this study is to: 1. Evaluate the efficacy of Adapalene gel 0.3% compared to Tretinoin Emollient cream 0.05%, reducing signs of cutaneous photoageing, measured trough photonumeric scale evaluation, investigator…
- Trial name
- FOTEN (NCT01406080)
- Testing
- Adapalene, Tretinoin
- Where
- 4 sites in Brazil
- Volunteers
- 128 people
- Sponsor
- Galderma Brasil Ltda.
Improve Photoaging Signs
Skin Care Regimen for Improving Photoaging Signs on the Face
Compare the effectiveness of laser treatment using CE Ferulic versus vehicle pre/post laser.
- Trial name
- NCT06603857
- Testing
- CE Ferulic, 1927nm (Clear and Brilliant Perméa®)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff