Clinical trials: Photodamaged Skin
Photodamaged Skin
Long-Pulsed Dye Laser and Intense Pulsed Light for Skin Rejuvenation.
The purpose of the trial is to compare clinical efficacy and occurrence of side effects in the treatment of photodamaged skin with Pulsed Dye Laser and Intense Pulsed Light.
- Trial name
- NCT00375141
- Testing
- Pulsed dye laser, Intense pulsed light
- Where
- Denmark
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Photodamaged Skin, Photoaging
Altreno for Chest Rejuvenation
This is a single-center, prospective, double-blind, randomized, vehicle-controlled study to evaluate the efficacy, safety and patient satisfaction of tretinoin 0.05% lotion (Altreno) for chest rejuvenation.
- Trial name
- NCT04096742
- Testing
- tretinoin 0.05% lotion (Altreno), Vehicle
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Hyperpigmentation, Photodamaged Skin
A Multi-Center, Open-label Study Evaluate the Efficacy and Tolerability of a Dual Skincare Regimen Treatment for Facial Hyperpigmentation and Photodamaged Skin in Patients Exposed to Extrinsic Factors of Aging
This open-label, multi-center clinical trial was conducted to evaluate the dual skincare regimen of vitamin C serum and moisturizing sunscreen SPF 45 to improve facial hyperpigmentation and photodamage after 12 weeks of twice…
- Conditions
- Hyperpigmentation, Photodamaged Skin, Wrinkle, Fine Lines
- Trial name
- NCT05423873
- Testing
- Gentle Cleansing Lotion, Revision Skincare
- Where
- 3 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Photodamaged Skin
Effect of Topical Agents With Various Antioxidant Containts on Photodamage Skin Induced
Ultraviolet (UV) irradiation of the skin leads to acute inflammatory reactions such as erythema, sunburn, and chronic reactions, including premature skin aging and skin tumors.
- Trial name
- NCT06170346
- Testing
- Antioxidants, Vehicle
- Where
- Indonesia
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran
Photoaging, Weight Loss
Evaluation of the Effects of a Biostimulator and Dermal Fillers for Cheek Augmentation and Contour Deficiencies
Adult subjects with a history of or currently taking glucagon-like peptide-1 (GLP-1) receptor agonist medication and moderate-to-severe cheek wrinkles and midface contour deficiencies will be treated with Sculptra correction of…
- Conditions
- Photoaging, Weight Loss, Skin Laxity, Photodamaged Skin
- Trial name
- NCT06351358
- Testing
- Sculptra treatment, Restylane Treatment
- Where
- 2 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Photodamaged Skin, Volume Deficiency of the Midface
A Study to Evaluate the Effects for Midface Improvement When Pairing a Biostimulator with a Skincare Regimen
To assess skin structural change in midface after treatment with a biostimulator using Line-Field Optical Coherence Tomography
- Trial name
- NCT05963204
- Testing
- Sculptra and Alastin Restorative Skin Complex, Sculptra and CeraVe Daily Moisturizing Lotion
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Atopic Dermatitis (AD), Psoriasis
A Clinical Evaluation of Marula-Derived Ceramide Cream on Skin Barrier Function Enhancement
Previously, the investigators have demonstrated in vitro the excellent efficacy of marula oil-derived ceramide NPs in enhancing skin barrier function.
- Conditions
- Atopic Dermatitis (AD), Psoriasis, Acne Vulgaris, Contact Dermatitis
- Trial name
- NCT07066150
- Testing
- Apply a cream containing 0.05% marula oil-derived ceramide NPs
- Where
- China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Shanghai Chicmax Cosmetic Co., Ltd.
Photodamaged Skin, Skin Care
A Clinical Study to Evaluate Efficacy and Tolerability of a Cosmetic Product for Arm Firming
This single-center, split-body, double-blind, randomized, controlled clinical trial was conducted to assess the efficacy and tolerance of a topical firming body moisturizer when used over the course of 12 weeks by women with mild…
- Trial name
- NCT04065035
- Testing
- Topical Body Firming Moisturizer, Body Cleanser, Sunscreen
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Photodamaged Skin
Placebo-Controlled Study Assessing the Use of a Novel Exfoliative Serum With A Chemical Peel to Improve Photodamage in Adults
This is a split-face, double-blind, placebo-controlled study assessing the use of a novel exfoliative serum with a chemical peel to improve photodamage in healthy female subjects between the ages of 30 and 65 years, inclusive…
- Trial name
- NCT05908825
- Testing
- Vitamin C with AHA Exfoliative Serum
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Austin Institute for Clinical Research
Photodamaged Skin
Study Comparing Two Serums With Intense Pulsed Light for the Treatment of Moderate to Severe Photodamage and Crepiness on the Forearms
The primary objective is to compare Re-Q Pro-Longevity serum versus vehicle serum combined with Intense Pulsed Laser for the treatment of moderate to severe photodamage and crepiness on the dorsal forearms.
- Trial name
- NCT07686198
- Testing
- Right Arm treated with Active Re-Q Pro-Longevity Serum and Intense Pulsed Light Therapy, Left Arm treated with vehicle serum and Intense Pulsed Light Therapy
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Photodamaged Skin
A Study to Evaluate and Compare the Efficacy of Two Facial Creams on Moderately to Severely Photodamaged Skin
The objective of this study is to evaluate the efficacy of a retinol alternative-containing facial cream in improving skin texture, radiance/brightness, and the appearance of fine lines, wrinkles, uneven skin tone, and dark…
- Trial name
- NCT06852742
- Testing
- Facial Cream A, Facial Cream B
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Photodamaged Skin
A Study to Assess the Effects of an Oral Dietary Supplement on Overall Facial Appearance Among Healthy Adult Women With Existing Skin Damage From Sun Exposure
The study hypothesis is that Imedeen will show effects on skin health, when compared to placebo over a 6 month intervention period with respect to changes in skin appearance, skin density, moisture, and in fine lines and wrinkles.
- Trial name
- NCT01787461
- Testing
- Imedeen
- Where
- 4 sites in United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Pfizer
Skin Wrinkling
Mechanisms of Skin Repair by Topical Estrogen
The purpose of this study is to investigate the way by which estrogen improves the appearance of sun damaged human skin. Accumulating evidence suggests that estrogen, taken by post menopausal women, may cause skin to look younger…
- Trial name
- NCT00113100
- Testing
- Topical 17-beta estradiol in ethanol/propylene glycol (ETOH/PG)
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Photoaged Skin, Normal Skin
Immunologic Profile of Chronically Photodamaged Skin
Chronically photodamaged skin is visually characterized by dryness, wrinkles, brown spots, leathery appearance, etc. This happens as a result of excessive exposure to UV light from the sun.
- Trial name
- NCT02889159
- Testing
- Candida albicans antigen, histamine phosphate, imiquimod 5% cream
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Skin Diseases
Transepidermal Application of Metilaminolevulinate in Daylight PDT in the Treatment of Photodamaged Skin
Chronic sun exposure enhances the incidence of cutaneous neoplasms (NMSC - non melanoma skin cancer), wrinkles, roughness, telangiectasia and irregular pigmentation of the skin.
- Trial name
- NCT03963765
- Testing
- Group I (Standard DL-PDT), Group II (DL-PDT with microneedles), Group III (DL-PDT with CO2 laser)
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Hyperpigmentation, Melasma
Annurca Apple Peel Oleolite for the Treatment of Skin Hyperpigmentation
The aim of this cosmetic clinical trial is to learn if an oleolite derived from Annurca Apple peel (AAO) works to enhance skin tone and luminosity, by counteracting the visibility of skin hyperpigmentation and dark spots in adult…
- Conditions
- Hyperpigmentation, Melasma, Skin Spots, Photodamaged Skin
- Trial name
- EAAO22G01 (NCT07040345)
- Testing
- Annurca apple oleolite
- Where
- Italy
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ritamaria Di Lorenzo