Clinical trials: Photoprotection
Pigmentation, Redness
Photoprotection Efficacy With Sunscreen Formulas Containing the Cyclic Merocyanine Long-UVA Absorber MCE Under Long-UVA Exposure
To evaluate the photo-protector effect of BC_3 (E212657) formulated in SPF compared to SPF alone on long-UVA induced pigmentation in healthy volunteers.
- Trial name
- NCT04865094
- Testing
- cyclic merocyanine
- Where
- Romania
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Visible Light Exposure on Healthy Back Skin
Evaluation of the Photoprotection Efficacy of Three Sunscreen Products Under Visible Light Exposure.
To evaluate the protective effect of three sunscreens products on the pigmentation caused by visible light in comparison to an untreated control zone in healthy volunteers.
- Trial name
- NCT06796205
- Testing
- Treated zones exposed with Visible Light source, Untreated zone exposed with Visible Light source
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Real Life Pigmentation
Photoprotection Efficacy With Sunscreen Formulas Containing the Cyclic Merocyanine Long-UVA Absorber MCE, Under Real Sun Exposure
To evaluate the photo-protector effect of BC_3 (E212657) formulated in SPF30 compared to SPF30 alone on real sun exposure induced pigmentation in healthy volunteers
- Trial name
- NCT04865055
- Testing
- cyclic merocyanine
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Visible Light Exposure on Healthy Back Skin
Photoprotection Efficacy of Different Topical Agents Under Visible Light Exposure
To evaluate the protective effect of seven sunscreens on the pigmentation induced by visible light in comparison to an untreated control zone in healthy volunteers
- Trial name
- NCT06796153
- Testing
- Visible Light Exposure - Treated zones, Visible Light Exposure - Untreated zone
- Where
- Romania
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Phototoxicity
Prevention of Phototoxicities in Patients Undergoing Vemurafenib Treatment
Vemurafenib is an anti-cancer treatment indicated as monotherapy in the treatment of adult patients with non-resectable or metastatic melanoma carrying a BRAF V600 mutation.
- Trial name
- NCT03108209
- Testing
- Photoderm Max lait SPF50+, Photoderm Max Stick SPF50+
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Michele Sayag
Aging
Evaluation of Efficacy of Anthelios Sunscreen on Face Versus Usual Routine on Signs of Aging
This experimental, randomized study aims at evaluating the preventative effect of a Sun Protection Factor (SPF) 50+ sunscreen (Anthelios UVMUNE 400 Fluid SPF 50+) with high Ultraviolet A (UVA) protection on clinical signs of skin…
- Trial name
- NCT06697288
- Testing
- Tested product group, Control group
- Where
- Brazil
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Actinic Keratosis (AK)
Study of the Photoprotection and Prevention of Actinic Damage With Anthelios Fluide 100 KA+ UVMune 400 in Patients With Multiple Actinic Keratoses
Participants will be invited to take part in a research study as they have been diagnosed with multiple actinic keratosis lesions (AK).
- Trial name
- NCT07335003
- Testing
- Tested product group, Control group
- Where
- Australia
- Volunteers
- 80 people
- Sponsor
- Cosmetique Active International
Polymorphic Light Eruption (PLE)
Phase III Trial of CUV1647 in Polymorphic Light Eruption (PLE)
The purpose of this study is to determine whether the afamelanotide (CUV1647) formulation is effective in preventing PLE episodes or reducing the severity of PLE symptoms in patients with a well documented history of the disease.
- Trial name
- NCT00472901
- Testing
- Afamelanotide (CUV1647)
- Where
- 3 sites in Australia, Austria and 1 more
- Volunteers
- 18 people
- Sponsor
- Clinuvel Pharmaceuticals Limited
Study the Potency of Sunscreen to Protect Against the Pigmentation Induced by Visible Light Exposure on Healthy Back Skin
Evaluate the Photoprotection Efficiency of Sunscreen Formulas Under Visible Light Exposure
To evaluate the protective effect of three sunscreens on the pigmentation caused by visible light in comparison to an untreated control zone in healthy volunteers.
- Trial name
- NCT06796088
- Testing
- Treated zones exposed to Visible Light source, Untreated zone exposed to Visible Light source
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Visible Light Exposure, Healthy Back Skin
Photoprotection Efficacy of Four Sunscreen Formulas Under Visible Light Exposure
To evaluate the protective effect of four sunscreens on the pigmentation caused by visible light in comparison to an untreated control zone in healthy volunteers.
- Trial name
- NCT06796010
- Testing
- Visible Light Exposure - Treated zones, Visible Light Exposure - Untreated zone
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Pigmentation, Redness
Photoprotection Efficacy With Sunscreen Formulas Containing the Cyclic Merocyanine Long-UVA Absorber MCE Under UV Day Light Exposure
To evaluate the photo-protector effect of BC_3 (E212657) formulated in SPF compared to SPF alone on UV Day Light induced pigmentation in healthy volunteers
- Trial name
- NCT04866797
- Testing
- cyclic merocyanine
- Where
- Romania
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Ultraviolet-Induced Change in Normal Skin
UVA Protection Factors of SPF 50 and 50+ Face Sunscreens
The goal of this observational study is to use the International Organization for Standardization (ISO) 24442:2011 in vivo method for assessment of the Ultraviolet A Protection Factor (UVAPF) of topical sunscreen products in…
- Trial name
- NCT06068010
- Where
- 6 sites in Brazil, France and 2 more
- Volunteers
- 412 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Sunscreen Sensitivity, Ultraviolet-Induced Change in Normal Skin
Photoprotection Efficacy With Sunscreen Formulas Containing the Cyclic Merocyanine Long-UVA Absorber MCE Under Long-UVA Exposure.
To evaluate the photo-protector effect of BC_3 (E212657) formulated in SPF compared to SPF alone on long-UVA induced pigmentation in healthy volunteers.
- Trial name
- NCT04865120
- Testing
- cream cyclic merocyanine
- Where
- Romania
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Efficacy of Sunscreen Products, Healthy Back Skin
Evaluation of the Photoprotection Efficacy with Sunscreen Formulas Under Visible Light Exposure
To evaluate the protective effect of three sunscreens on the pigmentation caused by visible light in comparison to an untreated control zone in healthy volunteers.
- Conditions
- Efficacy of Sunscreen Products, Healthy Back Skin, Pigmentation Induced by Visible Light Exposure
- Trial name
- NCT06803901
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Actinic Keratoses, Carcinoma, Squamous Cell
Phase II AK Study in Organ Transplant Patients
The purpose of this study is to determine whether afamelanotide (CUV1647) is effective in reducing the number of actinic keratoses and squamous cell carcinomas developing in immune compromised organ transplant recipients, who are…
- Conditions
- Actinic Keratoses, Carcinoma, Squamous Cell, Organ Transplant Recipients
- Trial name
- NCT00829192
- Testing
- Afamelanotide (CUV1647)
- Where
- 12 sites in Australia, Belgium and 5 more
- Volunteers
- 200 people
- Sponsor
- Clinuvel Pharmaceuticals Limited
Visible Light Exposure on Healthy Back Skin
Determine the Photoprotection Efficacy of Seven Sunscreen Products Under Visible Light Exposure.
To evaluate the protective effect of seven sunscreens on the pigmentation caused by visible light in comparison to an untreated control zone in healthy volunteers.
- Trial name
- NCT06796179
- Testing
- Visible Light Exposure - Treated zones with sunscreen products, Visible Light Exposure - Untreated zone
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Visible Light Exposures on Healthy Back Skin
Photoprotection Efficacy of a Sunscreen Under Visible Light Exposure by Using Two Different Simulators
To assess the ability of a protected agent to prevent the pigmentation under visible light exposures (VL) using two different simulators in healthy volunteers
- Trial name
- NCT06796140
- Testing
- Visible Light Exposure - Treated zone - Left hemi-back, Visible Light Exposure - Treated zone - Right hemi-back, Visible Light Exposure - Untreated zone - Left hemi-back
- Where
- Romania
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Study the Protection Potency of Sunscreen Products Against Pigmentation Induced by Visible Light Exposure on Healthy Back Skin
Evaluate the Photoprotection Efficacy of Sunscreen Formulas Under Visible Light Exposure
To evaluate the protective effect of three sunscreens on the pigmentation caused by visible light in comparison to an untreated control zone in healthy volunteers.
- Trial name
- NCT06796192
- Testing
- Visible Light Exposure - Treated zones, Visible Light Exposure - Untreated zone
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Efficiency of Agents, Against Pigmentation Induced by Visible Light Exposures
Photoprotection Efficiency with Sunscreen Formulas Under Visible Light Exposure.
To evaluate the protective effect of three Laboratoire VICHY formulations on the pigmentation caused by visible light in comparison to a non-treated control zone in healthy volunteers
- Trial name
- NCT06827392
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International