Clinical trials: Photorefractive Keratectomy
Refractive Surgery
Comparison of Outcomes Between TransPRK and Off-flap Epi-LASIK
To compare the quantitative and qualitative optical outcomes between single-step transepithelial photorefractive keratectomy (TransPRK) and off-flap epipolis laser in situ keratomileusis (Epi-LASIK) in moderate to high myopia.we…
- Trial name
- NCT05060094
- Volunteers
- 38 people
- Sponsor
- Wenzhou Medical University
Myopia
Codeine Plus Paracetamol Versus Placebo for PRK Post-operative Pain
Compare the use of codeine/paracetamol against placebo for pain control after cornea photorefractive keratectomy (PRK).
- Trial name
- NCT02625753
- Testing
- Codeine, paracetamol
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo General Hospital
Post-operative Pain Control
Post-operative Pain Control After Photorefractive Keratectomy Comparing Acetaminophen/Codeine vs Acetaminophen/Oxycodone
Photorefractive keratectomy (PRK) is a refractive error correction procedure that helps eliminate or reduce the dependence on corrective lenses. An important aspect of PRK is post-operative pain management.
- Trial name
- NCT04399122
- Testing
- acetaminophen/codeine vs acetaminophen/oxycodone
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- 59th Medical Wing
Anisometropic Amblyopia, Refractive Errors
Excimer Laser Surgery for Anisometropic Amblyopia
Study Objectives To compare the efficacy and safety of surgical treatment (PRK) versus non-surgical treatment of anisometropic amblyopia in children who have failed conventional treatment due to non-compliance or non-response.
- Trial name
- ATS19 (NCT03342235)
- Testing
- Photorefractive Keratectomy (PRK), Patching 2 hours per day, Excimer Laser System
- Sponsor
- Jaeb Center for Health Research
Astigmatism
Comparison of Cross-cylinder and Conventional Photorefractive Keratectomy(PRK) in Correcting Medium-high Astigmatism
The purpose of this study is to determine whether cross-cylinder approach is more effective than routine method in laser correction of astigmatism.
- Trial name
- PRK (NCT00663923)
- Testing
- photorefractive keratectomy (PRK)
- Where
- Iran
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tabriz University
Corneal Wound Healing
Sutureless Cryopreserved Amniotic Membrane Graft (ProKera) and Wound Healing After Photorefractive Keratectomy
The purpose of this study is to evaluate the effect of ProKera on corneal wound healing after photorefractive keratectomy (PRK) in terms of re-epithelialization, pain, adverse effects, visual recovery, refractive accuracy, and…
- Trial name
- NCT00915759
- Testing
- ProKera, Bandage contact lens
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Must be PRK Candidate
Safety and Efficacy of Lotemax Versus FML in Subjects Undergoing PRK for the Correction of Mild to Moderate Myopia, 3- Month Follow-up Study
STUDY OBJECTIVE: To evaluate and compare the safety and efficacy of (corneal Wound Healing and Intraocular Pressure) Fluorometholone and Loteprednol after photorefractive keratectomy (PRK) surgery.
- Trial name
- NCT02974387
- Testing
- Fluorometholone(FML), Loteprednol (Lotemax)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Dr Salouti Eye Research Center
Myopia
Comparison of Conventional and Custom Photorefractive Keratectomy (PRK)
The study objective is to compare the clinical outcomes using wavefront guided PRK with iris registration and conventional laser PRK using FDA-approved laser technology on the same patient.
- Trial name
- NCT00713856
- Testing
- Custom PRK with iris registration, Conventional PRK
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Utah
Keratoconjunctivitis Sicca
Goblet Cell Response and Dry Eye Symptoms After PRK and LASIK
Purpose: To develop a screening metric by examining both the characteristics of the preoperative tear film and the intracellular signaling pathways of conjunctival goblet cells in order to determine if there are certain…
- Trial name
- NCT00411827
- Testing
- PRK with conjunctival impression cytology before and after surgery, LASIK with conjunctival impression cytology before and after surgery
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Refraction Error, Photorefractive Keratectomy
Comparison of Ketorolac Tromethamine 0.5%-Soaked Bandage Contact Lenses Versus Non-Medicated Bandage Contact Lenses on Postoperative Pain Control After Photorefractive Keratectomy
Photorefractive keratectomy (PRK) is a well-established surface ablation procedure for the correction of refractive errors. Despite excellent visual and refractive outcomes, postoperative pain remains a significant concern…
- Trial name
- NCT07705763
- Testing
- Ketorolac Tromethamine 0.5%-Soaked Bandage Contact Lenses, Contact Bandage Lenses
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Madina Teaching Hospital Faisalabad
Keratoconus
Blurring Strength & Aberrometric Changes Following Corneal Cross-linking (CxL) and CxL Combined With Photorefractive Keratectomy (PRK) in Keratoconus
Primary objective of this study was to assess the impact of the two prevalent therapeutic options, CxL and CxL combined with topography-guided photorefractive keratectomy (t-PRK), on both anterior and posterior corneal High order…
- Trial name
- NCT01527721
- Testing
- Corneal Collagen Cross-Linking (CxL), Corneal Collagen Cross-Linking combined with t-PRK
- Where
- Greece
- Volunteers
- 32 people
- Sponsor
- Democritus University of Thrace
Photorefractive Keratectomy, Corneal Haze
Effect of Ectoine After Photorefractive Keratectomy (PRK).
This is a comparative, open label, parallel group, non interventional study aims to assess the effect of Ectoine containing eye drops on stromal haze, pain and epithelial healing after Photorefractive keratectomy (PRK).
- Trial name
- NCT05313425
- Testing
- Ectohylo (R) eye drops
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Tanta University