Clinical trials: Phototherapy
Premature; Infant, Light-for-dates
Cue-based Tactile Stimulation and Infant Stress Reactivity
The present study is an examination of cue-directed tactile stimulation (CTDS), administered by mothers and NICU nurses, on infant and maternal stress reactivity, infant immune system functioning, maternal parenting cognitions…
- Trial name
- NCT01121523
- Testing
- Cue directed tactile stimulation
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Penn State University
Sleep
Effects of Combined Blue and Red Home-Based Light Therapy on Sleep in Adults With Self-Reported Sleep Difficulties
The goal of this intervention is to learn if a combination of morning blue light and evening red light therapy can improve sleep quality in adults with subclinical sleep complaints (non-diagnosed difficulty initiating or…
- Trial name
- NCT07465250
- Testing
- LED portable light therapy bulb
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Secondary Caries
Reliability of Secondary Caries Detection Around Composite Restoration Using Light Induced Fluorescence
A total of 29 volunteer patients will be assigned in this study. Each patient should have one resin composite restoration. The restoration will be evaluated by two diagnostic methods (D), where D1 represents visual-tactile…
- Trial name
- NCT03558113
- Testing
- light induced fluorescence intraoral camera
- Where
- Egypt
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Cairo University
Myopia
Ambient Light Levels in the Kindergarten and Schools and the Relation to Refractive Development
Myopia, the most common human eye disorder, is a phenomenon characterized by an unconstrained elongation of the eye globe There are number of theories concerning the environmental effect on the emmetropization process, most are…
- Trial name
- NCT02854891
- Testing
- autorefractometer, A-scan ultrasound
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Vitiligo
Determining the Tolerance of Depigmented Skin to Targeted Phototherapy Using UVB in Patients With Vitiligo
The purpose of this study is to determine if vitiligo patients develop tolerance to ultraviolet light therapy, a type of treatment available for vitiligo.
- Trial name
- NCT00367224
- Testing
- 6 to 9 ultraviolet B treatments, Skin biopsies
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Acne
Blue Light Therapy of C. Acnes
This proposal aims to investigate a novel light-based treatment to reduce morbidity in shoulder surgical patients. This has potential to improve outcomes and reduce health care utilization associated with infectious complications…
- Trial name
- NCT04300010
- Testing
- 5% Topical Benzoyl Peroxide Gel, Blue Light Therapy
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Cataract
Dynamic Light Scattering for Studying Lens Aging and Cataract Formation
This study will use dynamic light scattering (DLS) technology to study normal lens aging and early cataract formation. Cataract is a clouding of the lens that interferes with the passage of light to the retina, impairing visual…
- Trial name
- NCT00081991
- Where
- United States
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Nanotechnology, Dental Materials, Composites
Nano Composites and Light Cure Composites - A Comparative Assessment of Bond Failure Rates
This randomized clinical trial is aimed to evaluate the bond failure rates of the brackets bonded with nano-hybrid composites (Filtek Z250) to that of conventional composites (Transbond XT)
- Trial name
- NCT05644860
- Testing
- Nanohybrid Compisite Group (Filtek Z250), Conventional Composite Group (Transbond XT)
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Healthy
Pigment-Tan-Safety Study of a Light-based Home Device for Hair Removal in Adult Subjects
This studies was designed to investigate the importance of skin type and UV-exposure on side effects after exposure to an Intense Pulsed Light Home-use device.
- Trial name
- NCT01763723
- Testing
- IPL-home use device
- Where
- Denmark
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Orthodontic Treatment, Bracket Failure
Comparison of One-Step and Two-Step Light Curing of Bonding Agents and Composite in Orthodontics
Effectiveness of One-Step Versus Two-Step Light Curing of Bonding Agent and Composite in Orthodontic Bracket Bonding: Study Design: A Randomized Controlled Trial (RCT) Study Type: Interventional Allocation: Randomized…
- Trial name
- 1STEP-2STEP-LC (NCT07491796)
- Testing
- One step light curing of bonding agent and composite, Two step light curing of bonding agent and composite
- Where
- Pakistan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
Keratoconus
Accelerated Corneal Collagen Crosslinking Protocols
To evaluate and compare the effect of pulsed light (pl-ACXL) accelerated and continuous light accelerated (cl-ACXL) epithelium-off cross-linking in halting the progression of keratoconus.
- Trial name
- NCT05693740
- Testing
- Accelerated crosslinking (ACXL)
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Assiut University
Striae Distensae
Clinical Evaluation of Using Intense Pulsed Light for Improving the Appearance of Striae Distensae
This trial is intended to evaluate the effect of IPL treatment on the Striae Distensae. The study hypothesis is that the SR580 applicator will improve the appearance of Striae Distensae by at least 1 point on the Global Aesthetic…
- Trial name
- NCT02452359
- Testing
- Venus Versa
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Venus Concept
UVB Phototherapy Burn, Insulin-like Growth Factor 1
Gene Expression Changes In Young and Geriatric Skin
This study does not involve any particular diagnosis. The goal of this research study is to explore the effects of artificial sunlight (ultraviolet B radiation; UVB) on the skin of young adults versus geriatric adults.
- Conditions
- UVB Phototherapy Burn, Insulin-like Growth Factor 1, Aging
- Trial name
- NCT03932162
- Testing
- Insulin-Like Growth Factor 1, No Insulin-Lie Growth Factor 1
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Wright State University
Narrowband Ultraviolet B-Induced Skin Erythema, Erythema
Mangosteen Gel for Sunburn-Like Skin Redness Caused by Ultraviolet B Light
The goal of this clinical trial was to learn whether a gel made from mangosteen (Garcinia mangostana) fruit rind helps sunburn-like skin redness fade faster when it is applied after the redness has already appeared.
- Conditions
- Narrowband Ultraviolet B-Induced Skin Erythema, Erythema, Sunburn, Erythema
- Trial name
- NCT07849842
- Testing
- Topical Garcinia mangostana Pericarp Extract Gel 2.5%, Topical Garcinia mangostana Pericarp Extract Gel 5%, Topical Garcinia mangostana Pericarp Extract Gel 10%
- Where
- Indonesia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hasanuddin University
Measurement of Pupil Diameter
Effects of Sevoflurane and Propofol on Light Flash Evoked Pupillometry
Null hypothesis (HO): There will be no difference in pupillometry readings when using any of the maintenance anesthetic techniques within subjects.
- Trial name
- NCT00695890
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Dentistry of New Jersey
Endometriosis, Infertility
Harnessing the Disease Signatures From Endometrium and Menstrual Blood to Identify Avenues for the Treatment of Chronic Conditions Such as Endometriosis and Related Pathologies: This is an Observational Study Aimed at Shedding Light on Women's Health
Many women's health conditions have limited treatments available and poor outcomes, in part due to the lack of understanding of disease processes and lack of data available.
- Conditions
- Endometriosis, Infertility, Endometrial Cancer, Adenomyosis, Endometriosis
- Trial name
- CYCLE_ENDO (NCT06990971)
- Testing
- No Intervention: Observational Cohort
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cycle Therapeutics Ltd
Risk Reduction Behavior
What is in Fact the Contribution of Reducing Time Spent in Sedentary Behaviors on Daily Energy Expenditure? A Doubly Labeled Water Study
The main purposes of this randomized cross-over trial are to test if a 3h/day reduction of time spent in sedentary behaviour (SB) through breaking up hourly and shifting it for standing and walking behaviours would substantially…
- Trial name
- NCT02007681
- Testing
- Reduction of sedentary time by breaking it with low intensity physical activity
- Where
- Portugal
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Technical University of Lisbon
Dentin Sensitivity
Evaluation of the Effect of Fluoride and Laser Application on the Prevention of Sensitivity in Bleached Teeth
To investigate the effects of desensitizing agents on the dental bleaching process, testing the hypothesis that they may prevent dental sensitivity.
- Trial name
- NCT03044171
- Testing
- Low Level Laser Therapy, 1.1% Sodium Fluoride, In-office dental bleaching
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Pain, Impairment, Light Touch Sensation
The Phonophoresis of Lidocaine Gel and Its Effect on Sensory Blockage
The optimisation of drug absorption through skin is of great value in modern therapy.Phonophoresis is the use of therapeutic ultrasound to increase percutaneous drug absorption.
- Trial name
- NCT01404468
- Testing
- pulsed ultrasound device with lidocaine, off device, continuous ultrasound device with lidocaine
- Where
- Iran
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Shiraz University of Medical Sciences
Cognitively Healthy People, Alzheimer Disease
Brain Effects of Gamma Frequency Sensory Stimulation (40Hz Light, Sound and Other Devices)
Despite the huge healthcare and economic impact of AD, there is still no disease modifying therapeutics available. In fact, the available therapeutics show low efficacy at best in the treatment of cognitive impairment in…
- Trial name
- GENUS (NCT07496918)
- Testing
- GENUS, Tactile GENUS
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Massachusetts Institute of Technology