Clinical trials: Phototherapy Complication
Premature, Retinopathy of Prematurity
Comfort Level in Premature Infants Undergoing Retinopathy of Prematurity Screening
Retinopathy of prematurity (ROP) screening is a routine yet painful procedure for premature infants, often necessitating pharmacological mydriasis.
- Conditions
- Premature, Retinopathy of Prematurity, Pain
- Trial name
- NCT07016984
- Testing
- standard phototherapy eye patches
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Istanbul Nisantasi University
Prematurity, Light-For-Dates
Early Human Milk Fortification After Early, Exclusive, Enteral Nutrition in Very Preterm Infants
In this proposed clinical trial, the investigators will randomize 80 very preterm (VPT) infants to receive either early (between day 4 and 7) or delayed (between day 10 and 14) fortification and determine if providing early…
- Conditions
- Prematurity, Light-For-Dates, Enteral Feeding Intolerance
- Trial name
- ENACT+ (NCT05525585)
- Testing
- Early HMF, Delayed HMF
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Alabama at Birmingham
Premature; Infant, Light-for-dates, Enteral Feeding Intolerance
Exclusive Enteral Nutrition in Preterm Neonates
To test the hypothesis that early exclusive enteral nutrition with the minimal use of parenteral nutrition will improve preterm infants' nutritional outcomes when compared to delayed progression of enteral nutrition and prolonged…
- Trial name
- ENACT (NCT04337710)
- Testing
- Exclusive Enteral Nutrition, Progressive Enteral Nutrition
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Alabama at Birmingham
Depression, Postpartum
The Effects of Light Therapy on Circadian Rhythms, Sleep, and Mood in Postpartum Depression
The proposed study aims to establish the feasibility of light therapy for postpartum depression delivered via Re-Timer, demonstrate its preliminary efficacy, and illuminate relationships between circadian shifts and mood changes…
- Trial name
- NCT02769858
- Testing
- Light therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Michigan
Diabetic Neuropathies
Light-emitting-diode in Diabetic Subjects
Diabetes mellitus (DM) is a metabolic disorder, characterized by hyperglycemia and metabolic disorders, resulting in changes in insulin secretion and / or action.
- Trial name
- NCT03369834
- Testing
- Red Light-emitting diode device, Infrared Light-emitting diode device, Infrared and Red Light-emitting diode device
- Where
- Brazil
- Volunteers
- 65 people
- Sponsor
- Rinaldo Roberto de Jesus Guirro
Overactive Bladder, Urinary Incontinence
Low-level Light Therapy for Overactive Bladder and Urinary Incontinence
This study aims to evaluate the effectiveness of a self-therapeutic approach of skin adhesive low-level light therapy (LLLT) in females with Overactive Bladder (OAB) and Urinary Incontinence (UI)
- Trial name
- NCT02980328
- Testing
- Low-level light therapy
- Where
- 2 sites in South Korea
- Volunteers
- 120 people
- Sponsor
- Seoul National University Hospital
Cancer
Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients
RATIONALE: Liposomal amphotericin B may be effective in controlling fever and granulocytopenia. It is not yet known which regimen of liposomal amphotericin B is more effective in treating cancer patients who have these…
- Trial name
- NCT00003938
- Testing
- liposomal amphotericin B
- Where
- 24 sites in Belgium, Czechia and 13 more
- Volunteers
- 115 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Diabetic Macular Edema
Near-infrared Light (NIR) Therapy for Diabetic Macular Edema: A Pilot Study
Summary of Study Rationale Near-infrared light (NIR) via light-emitting diodes (LED) treatment promotes retinal healing and improve visual function following high intensity laser retinal injury by augmenting cellular energy…
- Trial name
- NIR (NCT00846092)
- Testing
- Warp 10 LED Device, Near-infrared light (NIR)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Medical College of Wisconsin
Bladder Cancer
Study to Improve Detection and Early Recurrence Rate in Bladder Cancer Patients Using Hexvix Fluorescence Cystoscopy
The purpose of this study is to document the additional detection of papillary bladder cancer and the reduced early recurrence due to the improved detection and resection of these tumors after Hexvix cystoscopy compared to…
- Trial name
- NCT00233402
- Testing
- Hexvix, Standard white light cystoscopy
- Where
- 25 sites in United States, Austria and 3 more
- Volunteers
- 789 people
- Sponsor
- Photocure
Infant Malnutrition, Light-For-Dates With Signs of Fetal Malnutrition
Early DHA/ARA Supplementation in Growth-restricted Very Preterm Infants: A Randomized Clinical Trial
Growth-restricted very preterm infants (VPT) are born without adequate fat mass (FM) deposits and low docosahexaenoic acid (DHA) concentrations.
- Conditions
- Infant Malnutrition, Light-For-Dates With Signs of Fetal Malnutrition, Premature, Nutrition Disorder, Infant
- Trial name
- NCT06207071
- Testing
- DHA
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Polycystic Ovary Syndrome
Light Fasting Diet and Magnesium in Polycystic Ovary Syndrome (PCOS)
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of reproductive age, which is associated with hormonal imbalances, dyslipidemia, chronic inflammation, and increased oxidative stress, and…
- Trial name
- NCT07322120
- Testing
- Light fasting, Magnesium supplementation
- Volunteers
- 46 people
- Sponsor
- Behnood Abbasi
Depression, Depression, Postpartum
Chronobiology, Sleep Related Risk Factors and Light Therapy in Perinatal Depression: the Life-ON Project
In a 3 years longitudinal, observational, multicentre study, about 500 women will be recruited and followed-up from early pregnancy (10-15 gestational week) until 12 months after delivery.
- Conditions
- Depression, Depression, Postpartum, Depressive Disorder, Depressive Disorder, Major
- Trial name
- NCT02664467
- Testing
- Philips EnergyUp EnergyLight HF3419/01
- Where
- Switzerland
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Ospedale Regionale di Lugano
Diabetic Foot Ulcer
Laser Therapy for At-Home Treatment of DIabetic Foot Ulcers
The global prevalence of diabetes is on the rise and with it increase in prevalence of diabetic foot ulcers (DFU). These recalcitrant wounds are difficult to manage and pose a heavy economic burden.
- Trial name
- LLL&DIAB-01 (NCT03687320)
- Testing
- B-Cure Pro
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Erika Carmel ltd
Bacterial Vaginosis, Fungal Vaginal Infections
Clinical Protocol CERN Feasibility Study
The goal of this clinical trial is to learn if the intravaginal Cern device works to treat bacterial vaginosis and fungal vaginitis in premenopausal women. It will also learn about the safety of the device.
- Trial name
- NCT06933420
- Testing
- Cern Device
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- Cern Corporation
NMIBC, MIBC
Outcomes for IR and High Risk (HR) Non-muscle Invasive Bladder Cancer (NMIBC) and ctDNA-based Biomarkers for Response and Recurrence in Muscle Invasive Bladder Cancer (MIBC)
This study aims to better understand how treatment choices impact outcomes for patients with intermediate- and high-risk non-muscle-invasive bladder cancer (NMIBC), as well as the factors that influence treatment decisions made…
- Conditions
- NMIBC, MIBC, Muscle Invasive Bladder Cancer (MIBC), Non Muscle Invasive Bladder Cancer
- Trial name
- BLAST (NCT07893509)
- Testing
- This is a non-interventional, observational, prospective study.
- Where
- United States
- Volunteers
- 1,400 people
- Sponsor
- Bladder Cancer Advocacy Network
Cervical Intraepithelial Neoplasia
Clinical Evaluation of Polarized Light Assisted Colposcopy
This is a prospective study to compare unpolarized (conventional) to polarized light colposcopy. Subjects will be asked to participate in the study when they arrive for their prescheduled colposcopic examination.
- Trial name
- NCT01349621
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Augusta University
Bladder Cancer
High-power Green-light Laser Endoscopic Submucosal Dissection for Non-muscle-invasive Bladder Cancer
A retrospective study was designed in this study. The surgeon performed high-power green-light laser endoscopic submucosal dissection (HPL-ESD) for the treatment of primary non-muscle-invasive bladder cancer (NMIBC).
- Trial name
- NCT05290623
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Shandong Provincial Hospital
Bacterial Vaginosis, Vulvovaginal Candidiases
Light Treatment of Vaginal Infections in Reproductive Age Women
Antimicrobials have helped in managing vaginal dysbiotic conditions such as bacterial vaginosis (BV) and vulvovaginal candidiasis (VVC).
- Trial name
- NCT06985433
- Testing
- Vaginal light therapy - Once, Vaginal Light Therapy - Twice
- Where
- Denmark
- Volunteers
- 38 people
- Sponsor
- UVISA Health ApS
Depression, Light; Therapy, Complications
ROOM-LIGHT: Dynamic LED-light as Treatment for Depressed Patients in Inpatient Wards
Depression is a major health challenge, and despite developments in pharmacotherapy and psychotherapy a substantial part of patients will only recover very slowly and incompletely, and 10-25 % of the patients are resistant to…
- Conditions
- Depression, Light; Therapy, Complications, Sleep Disorders, Circadian Rhythm
- Trial name
- ROOM-LIGHT (NCT03363529)
- Testing
- Dynamic light, Standard
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Benign Prostate Hyperplasia, Urinary Retention
Prostatic Artery Embolization Versus 532 nm Green Light PVP for Catheterized Patients
The primary objective is to assess whether prostatic artery embolization has a similar efficacy and safety profile as GreenLight PVP in treating patients with urinary retention secondary to benign prostate hyperplasia (BPH).
- Trial name
- NCT02006303
- Testing
- Green light PVP, Prostatic artery embolization
- Where
- 2 sites in Canada
- Volunteers
- 73 people
- Sponsor
- Royal Victoria Hospital, Canada