Clinical trials: Phrenic Nerve Paralysis
Respiratory Paralysis
Diaphragmatic Height Index: the New Diagnostic Test for Phrenic Nerve Dysfunction
Diaphragmatic contraction is controlled by phrenic nerve which consists of anterior rami of 3rd- 5th cervical nerve roots. Usually, It can't be evaluated from history taking and physical examination.
- Trial name
- NCT01450917
- Volunteers
- 245 people
- Sponsor
- Mahidol University
Anesthesia, Local, Phrenic Nerve Paralysis
Interscalene Brachial Plexus Block Washout to Reverse Inadvertent Phrenic Nerve Blockade
One of the most frequently performed peripheral nerve blocks (the injection of local anesthetic near nerves to block sensation/ movement to a specific part of the body) is the interscalene brachial plexus block for upper…
- Conditions
- Anesthesia, Local, Phrenic Nerve Paralysis, Upper Extremity Injury, Phrenic Nerve Palsy on the Left
- Trial name
- NCT03677778
- Testing
- Normal saline injected via interscalene nerve catheter
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Stanford University
Diaphragm Issues, Diaphragm; Paralysis, Due to Accidental Section of Phrenic Nerve During Procedure
A Chart Review to Evaluate the Safety and Efficacy of Phrenic Nerve Reconstruction for the Treatment of Diaphragmatic Paralysis
A retrospective chart review to evaluate the safety and efficacy of phrenic nerve reconstruction for diaphragmatic paralysis.
- Conditions
- Diaphragm Issues, Diaphragm; Paralysis, Due to Accidental Section of Phrenic Nerve During Procedure, Breath Shortness, Diaphragmatic Paralysis
- Trial name
- NCT06257589
- Where
- 2 sites in United States
- Volunteers
- 700 people
- Sponsor
- Advanced Reconstructive Surgery Alliance
Diaphragmatic Paralysis, Anterior Suprascapular Nerve Block
Combined Anterior Suprascapular Nerve Block and Superficial Cervical Plexus Block In Shoulder Arthroplasty Surgery
The suprascapular nerve, originating from the C5 trunk, provides innervation to the acromioclavicular and glenohumeral joints. The supraclavicular nerve, a branch of the cervical plexus, contributes to the sensory innervation of…
- Conditions
- Diaphragmatic Paralysis, Anterior Suprascapular Nerve Block, Superficial Cervical Plexus Block, Phrenic Nerve Paralysis
- Trial name
- NCT06146179
- Where
- Turkey (Türkiye)
- Volunteers
- 8 people
- Sponsor
- Istanbul Medeniyet University
Phrenic Nerve Paralysis
the Clinicaltrail of the Effection Which of Phrenic Block Using in Non-intubated Video-assisted Thoracoscopic Surgery
Putting 80 patients divided into group S（non-intubated general anesthesia combine with Paravertebral blocks、surface spray anesthesia and Vagus block） and group D（non-intubated general anesthesia combine with Paravertebral…
- Trial name
- NCT03653494
- Testing
- phrenic block, no phrenic block
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Shenzhen People's Hospital
Phrenic Nerve Paralysis, Diaphragm Sellae Meningioma
Comparison of Different Approaches for Supraclavicular Block and Their Effects on Diaphragm Muscle Function
Brachial plexus blocks used for anesthesia in upper extremity operations can be performed with interscalene, axillary, supraclavicular and infraclavicular approaches.
- Conditions
- Phrenic Nerve Paralysis, Diaphragm Sellae Meningioma, Complications, Respiratory Complication
- Trial name
- NCT04756050
- Testing
- Bupivacaine HCl 0.5% Injectable Solution, Prilocaine HCl % 2 injectable solution, adrenaline amp 0.5mg
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bozyaka Training and Research Hospital
Phrenic Nerve Paralysis
Supraclavicular Block vs Retroclavicular Block: Incidence of Phrenic Nerve Paralysis
The aim of this study is to evaluate differences between ultrasound guided supraclavicular versus retroclavicular brachial plexus blocks: two similar brachial plexus nerve block techniques that differ in their needle trajectory…
- Trial name
- NCT02631122
- Testing
- Supraclavicular vs Retroclavicular Nerve Block
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Brigham and Women's Hospital
Diaphragm; Paralysis
Neck Anatomy and Phrenic Nerve Palsy After BPB
The purpose of this study was to determine the association between the anatomical characteristics of neck and postoperative diaphragmatic paralysis in patients undergoing interscalene brachial plexus block before shoulder…
- Trial name
- NCT04783064
- Testing
- Interscalene brachial plexus block
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital
Diaphragmatic Paralysis, Pain, Chest
Phrenic Nerve Reconstruction for the Treatment of Diaphragmatic Paralysis: Patient Experiences and Reported Outcomes.
This study utilizes a grounded theory methodology to explore patient experiences of phrenic nerve reconstructive surgery as a treatment for diaphragmatic paralysis.
- Conditions
- Diaphragmatic Paralysis, Pain, Chest, Breath Shortness
- Trial name
- NCT06243718
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- Advanced Reconstructive Surgery Alliance
Diaphragmatic Paralysis
Effects of Inspiratory Muscle Training on Exertional Breathlessness in Patients With Unilateral Diaphragm Paralysis
Treatment options for unilateral diaphragm paralysis are limited. Diaphragmatic plication via mini thoracotomy is sometimes considered in the University Hospital Leuven if severe symptoms persist for longer than 12 months after…
- Trial name
- NCT04563468
- Testing
- Strength inspiratory muscle training, Endurance inspiratory muscle training
- Where
- Belgium
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Prolonged Air Leak, Phrenic Nerve
Postoperative Effects of Intraoperative Temporary Phrenic Nerve Paralysis in Lung Resection Surgery
This prospective clinical study aimed to evaluate the postoperative effects of temporary phrenic nerve paralysis induced by intraoperative phrenic nerve crush during lung resection surgery.
- Conditions
- Prolonged Air Leak, Phrenic Nerve, EMG
- Trial name
- PNCrush (NCT07259031)
- Testing
- İntraoperative phrenic nerve compression
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Ferdane Melike Duran
Phrenic Nerve Paralysis
Comparison of Costoclavicular Brachial Plexus Block and Supraclavicular Brachial Plexus Block
The investigator will compare Costoclavicular approach of infraclavicular block and supraclavicular block. Especially, the incidence of phrenic nerve palsy and the quality of block.
- Trial name
- BPB (NCT03097159)
- Testing
- Costoclavicular block
- Where
- South Korea
- Sponsor
- Ajou University School of Medicine
Phrenic Nerve Palsy
Does Saline Injection Around Phrenic Nerve Reduce Incidence of Diaphragmatic Paresis Following Interscalene Block?
Hemi-diaphragmatic palsy is a common undesirable effect of interscalene block, with an incidence of up to 100%. Mechanism of palsy is thought to be related to spread of local anaesthetic anterior to the anterior scalene muscle.
- Trial name
- NCT02893228
- Testing
- Saline, Levobupivacaine
- Where
- Ireland
- Volunteers
- 36 people
- Sponsor
- The Adelaide and Meath Hospital, incorporating The National Children's Hospital
Regional Anesthesia Morbidity, Complication Following Peripheral Nerve Block
Comparison of the Effects of Interscalene Block and Superior Trunk Block on Pulmonary Functions
The interscalene block (ISB) is one of the peripheral nerve blocks providing surgical anesthesia and postoperative analgesia in shoulder arthroscopy, eliminating the need for general anesthesia.
- Conditions
- Regional Anesthesia Morbidity, Complication Following Peripheral Nerve Block, Phrenic Nerve Paralysis
- Trial name
- NCT06703281
- Testing
- Interscalene Nerve Block, Superior trunk block
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people
- Sponsor
- Gazi University
Phrenic Nerve Paralysis
Evaluation of Diaphragm Movement After an Interscalene Block
The purpose of this study is to evaluate the movement of the diaphragm after an interscalene block with liposome bupivacaine (LB) compared to interscalene block (IB) with bupivacaine.
- Trial name
- NCT03636542
- Testing
- liposomal bupivacaine, bupivacaine
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Minnesota
Hemidiaphragmatic Paralysis, Postoperative Pain
Comparative Evaluation of Diaphragmatic Function Following Interscalene, Anterior Suprascapular, and Costoclavicular Nerve Blocks in Shoulder Surgery
Shoulder surgery causes significant postoperative pain, and ultrasound-guided regional anesthesia is central to its management. The interscalene block (ISB) is the gold standard but frequently causes phrenic nerve paralysis and…
- Conditions
- Hemidiaphragmatic Paralysis, Postoperative Pain, Shoulder Surgery, Brachial Plexus Block
- Trial name
- NCT07671352
- Testing
- Ultrasound-guided interscalene brachial plexus block, Ultrasound-guided suprascapular nerve block, Ultrasound-guided costoclavicular brachial plexus block
- Volunteers
- 75 people
- Sponsor
- Menoufia University
Anesthesia, Local, Phrenic Nerve Paralysis
Erector Spinae Plane Versus Interscalene Blocks for Shoulder Surgery
The goal of this study is the evaluation of erector spinae plane (ESP) blocks as an alternative to interscalene brachial plexus nerve blocks for rotator cuff repair and total shoulder arthroplasty procedures.
- Conditions
- Anesthesia, Local, Phrenic Nerve Paralysis, Upper Extremity Injury, Shoulder Injury
- Trial name
- NCT03807505
- Testing
- Interscalene brachial plexus nerve block, Erector spinae plane block
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Vocal Cord Paralysis
Bilateral Laryngeal Paralysis Reinnervation
Bilateral laryngeal reinnervation induces a rise in laryngeal resistance and speech alteration. The aim of this study is to propose laryngeal reinnervation by a phrenic nerve root to patients with bilateral laryngeal paralysis.
- Trial name
- NCT00213616
- Testing
- surgical reinnervation
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Rouen
Tetraplegia
Diaphragmatic Reinnervation of Tetraplegic Patients With Respiratory Insufficiency
This study evaluates the diaphragmatic reinnervation by inferior laryngeal nerve in tetraplegic patients with ventilatory insufficiency.
- Trial name
- TETRADIA-UNI (NCT01350297)
- Testing
- reinnervation
- Where
- France
- Volunteers
- 5 people
- Sponsor
- University Hospital, Rouen
Phrenic Nerve Paralysis
Incidence of Hemidiaphragmatic Palsy After Interscalene Block
Primary objective of this study is to find out the incidence of hemi-diaphragmatic palsy associated with interscalene block done under ultrasound guidance.
- Trial name
- NCT01784601
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's