Clinical trials: Physical Activity
Prehypertension, Hypertension
Equity in Prevention and Progression of Hypertension by Addressing Barriers to Nutrition and Physical activitY
The goal of this study is to test an intervention to prevent high blood pressure among rural, Black adults living in Alabama. Black adults in this region have one of the highest rates of high blood pressure in the US.
- Conditions
- Prehypertension, Hypertension, Blood Pressure
- Trial name
- EPIPHANY (NCT05367544)
- Testing
- Health Education, Individual-Level Peer Support, Community-Level Peer Support
- Where
- United States
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Hyperkyphosis
Physical Therapy Exercises in Hyperkyphosis
This proposal is a single center preliminary prospective cohort trial that evaluates patients with hyperkyphosis. Participants will receive physical therapy exercises and be followed for the above outcome measures over time.
- Trial name
- NCT03212664
- Testing
- exercise
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Texas Scottish Rite Hospital for Children
Childhood Obesity, Type 2 Diabetes
Cardiovascular Risk Factors, Body Composition, Fitness Levels And Quality Of Life In Overweight And Obese 8-17 Year Olds
This project will address the important area of childhood obesity and the risk of cardiovascular disease associated with obesity.
- Conditions
- Childhood Obesity, Type 2 Diabetes, Hypercholesterolemia, Hypertension
- Trial name
- NCT02024399
- Testing
- Exercise
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Crohn's Disease
A Study of TRK-170 for the Treatment of Crohn's Disease
In Crohn's Disease Patients To evaluate the efficacy of TRK-170 To evaluate the PK characteristics of TRK-170 To assess the safety of TRK-170
- Trial name
- NCT01345799
- Testing
- TRK-170
- Where
- 13 sites in Belgium, Bulgaria and 11 more
- Volunteers
- 123 people
- Sponsor
- Toray Industries, Inc
Advanced Solid Tumor
Phase 1 Trial of RP-3467 Alone and in Combination With Olaparib in Participants With Advanced Solid Tumors
This is a multicenter, open-label Phase 1 trial to investigate the safety, PK, and pharmacodynamics of the Polθ inhibitor RP-3467 alone or in combination with the poly-ADP ribose polymerase inhibitor (PARPi) olaparib in adults…
- Trial name
- POLAR (NCT06560632)
- Testing
- RP-3467 at assigned dose and schedule, Olaparib 200-300 mg BID, daily
- Where
- 5 sites in United States
- Volunteers
- 26 people
- Sponsor
- Repare Therapeutics
Athletic Performance, Athletic Performance Enhancement
Bench Press During Squat Conditioning and PAPE
The goal of this clinical trial is to learn whether adding a moderate-load bench press exercise during the recovery periods between sets of back squats affects subsequent jumping performance in competitive male basketball…
- Trial name
- NCT07765732
- Testing
- Back Squat Conditioning Activity, Bench Press During Inter-Set Recovery
- Where
- Poland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Healthy Volunteers
Forward and Backward Walking Exercise on Physical and Cognitive Functions
To investigate the acute effects of forward and backward walking exercise on physical functions such as static and dynamic balance and cognitive functions such as attention, concentration, memory, processing speed, visual…
- Trial name
- NCT06604416
- Testing
- Forward walking, Backward walking
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Atlas University
Intellectual Disability
Physical Activity, mHealth and Intellectual Disability - a Pilot Study
The main objective of this pilot study is to assess distant procedures, study experiences and feasibility of a planned randomized controlled trial investigating the use of a mHealth support tool on physical activity for…
- Trial name
- NCT04929106
- Testing
- mHealth support tool
- Where
- Norway
- Volunteers
- 9 people
- Sponsor
- University Hospital of North Norway
Inflammation
Enhancing Adaptations to Exercise
Researchers are trying to understand how chronic inflammation affects muscle function and responses to exercise.They are also trying to determine if suppressing chronic inflammation using omega-3 fatty acids (n3-PUFA) restores…
- Trial name
- NCT03350906
- Testing
- n3-PUFA, Biopsy, Body Composition Scan
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Heart Disease, Heart Failure With Preserved Ejection Fraction
Acute Effects of Inorganic Nitrite on Cardiovascular Hemodynamics in Heart Failure With Preserved Ejection Fraction
Heart failure with preserved ejection fraction (HFpEF) is a major public health problem that has no proven effective treatment. This study assessed the effects of acute nitrite administration on resting and exercise hemodynamics…
- Conditions
- Heart Disease, Heart Failure With Preserved Ejection Fraction, Exercise Intolerance, Pulmonary Hypertension
- Trial name
- NCT01932606
- Testing
- Nitrite
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Barry Borlaug
Exercise-induced Pulmonary Arterial Hypertension
An Open-Label Uncontrolled Study of the Safety and Efficacy of Ambrisentan in Participants With Exercise-Induced Pulmonary Arterial Hypertension (PAH)
The purpose of this study is assess whether ambrisentan can help people with exercise- induced pulmonary arterial hypertension (EIPAH).
- Trial name
- EiPAH (NCT01338636)
- Testing
- Ambrisentan
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Brigham and Women's Hospital
Resistance Exercise
Effect of a Novel Blend of Plant Protein and Additional Ingredients on Resistance Training Adaptations
This study seeks to compare the observed changes in resistance training adaptations (strength, performance, body composition, recovery, and lactate responses) after supplementation of isocaloric and isonitrogenous amounts of a…
- Trial name
- IOV (NCT06908811)
- Testing
- Novel Plant Protein Blend, Pea/Rice Protein Blend, Whey Protein
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Lung Cancer
Preliminary Efficacy of Different Exercise Training During Immunotherapy in Patients With Lung Cancer: The ENHANCE Trial
The purpose of this study is to examine the feasibility and effects of 12-week exercise training at different intensities among individuals with advanced lung cancer receiving immune checkpoint inhibitors.
- Trial name
- ENHANCE (NCT06026111)
- Testing
- High-Intensity Interval Training (HIIT), Moderate-Intensity Continuous Training (MICT)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Dana-Farber Cancer Institute
Solid Tumor, Gastric Cancer
A Phase I Trial of CCT303-406 in Patients With Relapsed or Refractory HER2 Positive Solid Tumors
This clinical study is to investigate the safety and tolerability of CCT303-406 CAR modified autologous T cells (CCT303-406) in subjects with relapsed or refractory stage IV metastatic HER2-positive solid tumors.
- Conditions
- Solid Tumor, Gastric Cancer, Breast Cancer, Ovarian Cancer
- Trial name
- NCT04511871
- Testing
- CCT303-406
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Shanghai PerHum Therapeutics Co., Ltd.
Chronic Conditions, Multiple
A Physiotherapy-led Disease-agnostic Telerehabilitation Programme for People With Chronic Health Conditions
This protocol outlines a planned mixed methods feasibility trial which will be conducted to examine the feasibility and acceptability of a physiotherapy-led exercise-based telerehabilitation programme for groups of people with…
- Trial name
- NCT06388499
- Testing
- TECC (Telerehabilitation and Exercise for Chronic Conditions)
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- University of Limerick
Attention Deficit Hyperactivity Disorder (ADHD)
Impact of Structured Exercise Programs on Cognitive, Motor and Behavioral Outcomes in Children With ADHD
The purpose of this study is to investigate the effects of structured exercise interventions (Gince Zumba and Square Stepping) on cognitive, motor and behavioral functions of children diagnosed with Attention Deficit…
- Trial name
- ADHD (NCT07376863)
- Testing
- Gince Zumba Exercise, Square Stepping Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Cukurova University
Obesity
Randomized Controlled Clinical Trial of Weight Loss Programs in Obese Persons
The purpose of this study is to compare two approaches to a diet and exercise-based weight loss program.
- Trial name
- SHINE (NCT00960414)
- Testing
- SHINE
- Where
- United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
SPONDYLOARTHRITIS
Discontinuation of TNF-alpha Inhibitors in Patients With Spondyloarthritis
Spondylarthropathy (SpA) comprises a group of rheumatic diseases mainly affecting the spine and sacroiliac joints. In most of the patients disease activity alternates, and some patients have symptom free periods.
- Trial name
- SPARTA (NCT00726804)
- Testing
- Discontinuation of TNF-alpha inhibitor and re-starting it if flare-up in disease activity (etanercept or adalimumab)
- Where
- 6 sites in Denmark
- Volunteers
- 7 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Axial Spondyloarthritis (Ankylosing Spondylitis)
Mediterranean Diet and Disease Activity in Axial Spondyloarthritis Receiving Biologic Therapy
This study aims to evaluate the effect of the Mediterranean diet on disease activity, quality of life, inflammation, pain, and treatment response in patients with axial spondyloarthritis (ankylosing spondylitis) who are receiving…
- Trial name
- NCT07170384
- Testing
- Mediterranean Diet, Healthy Eating Advice
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Sinem Kübra Beke
Pulmonary Hypertension
Inspiratory Muscle Training in Pulmonary Hypertension
The aim of this study is to investigate the effective of inspiratory muscle training on respiratory function, exercise capacity, physical activity and quality of life.
- Trial name
- NCT03385733
- Testing
- inspiratory muscle training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul University
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