Clinical trials: Physical Activity
Dementia, Alzheimer Disease
Effects of a Multicomponent Exercise Intervention on Physical and Cognitive Function of Older Adults With Dementia
Dementia is a leading cause of death and disability that was declared as one of the greatest health and social care challenges of the 21st century.
- Conditions
- Dementia, Alzheimer Disease, Vascular Dementia, Neurocognitive Disorders
- Trial name
- Body&Brain (NCT04095962)
- Testing
- Exercise
- Where
- Portugal
- Volunteers
- 110 people
- Sponsor
- Universidade do Porto
Parkinson Disease
Exercise & Brain Energetics in PD
There is increasing evidence that the usage and delivery of energy to the brain, known as brain energetics, is altered in people with Parkinson's disease (PD).
- Trial name
- EBEPD (NCT04426786)
- Testing
- Active exercise, Passive exercise
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Pacific Parkinson's Research Centre
Stroke
Adaptive Physical Activity for Chronic Stroke
This study will compare the Adaptive Physical Activity program (APA) to a less vigorous group exercise program, (Sittercise) to see if APA leads to greater improvements in walking endurance, quality of life, and participation in…
- Trial name
- APA-Stroke (NCT00773370)
- Testing
- APA-Stroke, Sittercise
- Where
- 2 sites in United States
- Volunteers
- 76 people
- Sponsor
- VA Office of Research and Development
Bed Rest, Pregnancy
Physical Activity in Bed Rest Hospitalized High-Risk Pregnant Women
This pilot study aims to evaluate the impact of a specifically designed exercise program for hospitalized high-risk pregnant individuals on bed rest.
- Conditions
- Bed Rest, Pregnancy, Pregnancy Complications
- Trial name
- BedRest (NCT06713083)
- Testing
- Exercise
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Montse Palacio
Prostate Cancer
The Remote Study: Investigating the Effects or Online Exercise on Quality of Life in Men With Prostate Cancer
Currently, there are few opportunities for patients with cancer to have individual exercise guidance, and this has further been impacted by the Covid-19 pandemic.
- Trial name
- NCT05989854
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Surrey
Hepatitis C
A Study to Assess the Anti-viral Activity, Safety, Tolerability and Pharmacokinetics of TMC435350 in Participants Infected With Hepatitis C-Virus (HCV)
The purpose of this study is to assess anti-viral activity (inhibition of viral growth) of TMC435350 in genotype 2,3,4,5 and 6 hepatitis C virus infected participants who have never received treatment for their hepatitis C…
- Trial name
- NCT00812331
- Testing
- TMC435
- Where
- 10 sites in Belgium, Germany and 1 more
- Volunteers
- 37 people
- Sponsor
- Tibotec Pharmaceuticals, Ireland
Disorders, Substance Related
A Study on the Effects of Breathing Exercises and Aerobic Exercise on the Health of Men in Drug Rehabilitation
This study aims to investigate the effects of an 8-week combined exercise program on male individuals in drug rehabilitation. The program integrates resistance-based breathing training with aerobic exercise.
- Trial name
- NCT07592195
- Testing
- Resistance Breathing Training, Aerobic Exercise
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Southwest Medical University
Pregnancy Complications, Obesity
Acute Exercise Effects in Obese Pregnancy
Obesity before and during pregnancy is associated with a higher risk for a number of obstetric and metabolic complications in women and their offspring.
- Conditions
- Pregnancy Complications, Obesity, Pre-Eclampsia, Gestational Diabetes
- Trial name
- NCT03750695
- Testing
- Resistance exercise, Aerobic Exercise, Rest
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Duke University
Physical Activity, Behavior
A Walking Intervention Through Text Messaging
The purpose of this study is to develop and evaluate adaptive goal setting and feedback interventions (Adaptive Interventions) to promote physical activity behaviors and compare it to static physical activity interventions…
- Conditions
- Physical Activity, Behavior, Overweight, Motor Activity
- Trial name
- WalkIT (NCT02053259)
- Testing
- Adaptive Goals, Reinforcement, Static Goals
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Lung Cancer
Training Effects Following Resection Surgery in Patients With Lung Cancer
The purpose of this study is to determine the potential benefits resulting from a specific training on exercise tolerance and muscle function at the medium and long-time, as well as study its effects on plasmatic mediators…
- Trial name
- EMITOR (NCT01771796)
- Testing
- Aerobic and muscle resistance training
- Where
- 2 sites in Spain
- Volunteers
- 48 people
- Sponsor
- Parc de Salut Mar
Melanoma, Breast Carcinoma
A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumors
This is a Phase 1, multiple dose, ascending dose escalation study to define a MTD/RD and regimen of XmAb20717, to describe safety and tolerability, to assess PK and immunogenicity, and to preliminarily assess anti-tumor activity…
- Conditions
- Melanoma, Breast Carcinoma, Hepatocellular Carcinoma, Urothelial Carcinoma
- Trial name
- DUET-2 (NCT03517488)
- Testing
- XmAb20717
- Where
- 17 sites in United States
- Volunteers
- 150 people
- Sponsor
- Xencor, Inc.
Multiple Sclerosis
Open-Label Extension Study to Evaluate the Safety, Tolerability and Activity of Oral Fampridine-SR in Patients With Multiple Sclerosis
The purpose of this study is to evaluate the long-term safety, tolerability and activity of Fampridine-SR in subjects with multiple sclerosis who have previously participated in either an Acorda Therapeutics or an Elan…
- Trial name
- NCT00654927
- Testing
- Fampridine-SR b.i.d. (Twice Daily)
- Where
- 22 sites in United States, Canada
- Volunteers
- 177 people
- Sponsor
- Acorda Therapeutics
Resistance Exercise, Muscle Strength Development
Myo-Reps Versus Traditional Sets for Muscle Strength, Fat-Free Mass, and Time Efficiency
This study compared two ways of doing strength training in healthy adults. The first, called Myo-Reps, is a time-saving method: one hard first set of 8-15 repetitions, followed by three short "mini-sets" of 3-5 repetitions with…
- Trial name
- NCT07914361
- Testing
- Myo-Reps resistance training, Traditional three-set resistance training
- Where
- Norway
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Metabolism in Adipose Tissue
Interleukin-6 Secretion in Adipose Tissue Following Sprint Exercise
Low volume sprint exercise training has been shown to reduce body fat despite small total energy expenditure (for ref see Gillen and Gibala 2014). IL-6 has been shown to increase adipose tissue lipolysis in vitro.
- Trial name
- NCT04566354
- Testing
- Repeated 30-s sprint exercise
- Where
- Sweden
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Hypersomnia in Children
Amylase and Hypersomnia
Hypersomnia is defined as a reduced ability to remain awake during the day. There are basically two types of central hypersomnia: narcolepsy and idiopathic hypersomnia.
- Trial name
- Amylase (NCT01926405)
- Testing
- saliva collection
- Where
- France
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Cervical Pain
Effectiveness of Muscle Energy Technique (MET) Versus Stretching Exercises In Acute And Subacute Postural Neck Pain
This study will provide better evidence that which technique is more effective in acute and subacute postural neck pain. To find out the effectiveness of Muscle energy technique (MET) and stretching exercises in acute and…
- Trial name
- NCT06221566
- Testing
- Muscle Energy Technique, Stretching Exercises
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Dow University of Health Sciences
Physician Fatigue
Impact of a Day Without Clinical Activity Before Night Shift on Non-technical Skills of Intensive Care Residents
In this proposal, investigators seek to address conclusively two knowledge gaps: 1) the lack of data on the impact of a schedule including a day off clinic before night shift on performances of residents in anesthesia or critical…
- Trial name
- REPOPREGARD (NCT05146856)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Physical Exercise Behavior (Liking/Aversion)
Molecular and Functional Neurobiology of Physical Exercise
In this study, we use positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) to study brain mechanisms that contribute to physical exercise-induced reward.
- Trial name
- EXEBRAIN (NCT02615756)
- Testing
- Exercise
- Where
- Finland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Sedentary Behavior, Cardiometabolic Risk Factors
Breaking up Prolonged Sedentary Behavior to Improve Cardiometabolic Health
The purpose of this Phase 1 research study is to answer two questions: (1) How frequent should periods of prolonged sedentary time be interrupted? and (2) What is the appropriate duration or length of time of these breaks in…
- Conditions
- Sedentary Behavior, Cardiometabolic Risk Factors, Blood Pressure, Glucose
- Trial name
- NCT05353322
- Testing
- Sedentary Break (Walking) Condition, Sitting (Control) Condition, Controlled Diet
- Where
- United States
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Columbia University
Pre-Eclampsia; Complicating Pregnancy
Comparative Effects of Jacobson's Relaxation Techniques and Stretching Exercises in Preeclampsia
To compare the effect of Jacobson's Relaxation Techniques and stretching exercises on Preeclampsia in pregnant women.
- Trial name
- NCT05863962
- Testing
- walking and Stretching, walking and Jacobsons relaxation technique
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Riphah International University
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