Clinical trials: Physical Deconditioning
Physical Deconditioning
Effects of Training With a Pressure Cuff on Cellular Energy Activity
This study investigates low-load, cuff-assisted training to improve mitochondrial capacity. The intervention is carried out using automated pressure cuffs, applying an individualized pressure of 70% of the limb occlusion…
- Trial name
- NCT07494721
- Testing
- Application of pressure cuffs during strength training, Application of pressure cuffs during endurance training, Conventional clinical rehabilitation program without the use of pressure cuffs
- Volunteers
- 51 people
- Sponsor
- Spital Thurgau AG
Multimorbidity, Physical Deconditioning
Multicomponent Telerehabilitation to Engage Veterans in Effective Self-Management of Complex Health Conditions
Medically complex older Veterans are at greater risk for progressive declines in physical function, lower quality of life, and increasing care needs.
- Trial name
- NCT06288438
- Testing
- Motivational Interviewing Techniques, Physical Therapy Interventions, Education
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- VA Office of Research and Development
Hemodialysis, Kidney Disease, Chronic
Intradialysis Exercise Functional Capacity, Body Composition and Survival in Hemodialysis Patients
Chronic kidney disease and renal replacement treatments (hemodialysis, peritoneal dialysis, kidney transplant) produce various alterations at the level of muscle, bones, fat content and the heart; can alter physical capabilities…
- Conditions
- Hemodialysis, Kidney Disease, Chronic, Physical Activity, Physical Deconditioning
- Trial name
- NCT06788054
- Testing
- intradialysis exercise
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- Universidad de Guanajuato
Sedentary, Deconditioning
Eccentric Cycling : a Promising Training Modality for Sedentary People
The present study aims to compare the acute and training responses of (1) eccentric high intensity interval training (EI), (2)work-matched continuous eccentric training (EC), and (3) concentric high intensity interval training…
- Conditions
- Sedentary, Deconditioning, Eccentric Exercise Training, Eccentric Cycling Exercise
- Trial name
- NCT07189975
- Testing
- High intensity eccentric cycling training, Moderate intensity eccentric cycling training, High intensity concentric cycling training
- Where
- Belgium
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Liege
Children With Cerebral Palsy, Children With Cancer
Evaluation of the Effect of a Physical Activity Recovery Stay
A WHO study in 2020 revealed that 81% of adolescents (aged 11-17) do not respect the recommendation of one hour of moderate physical activity per day. In the context of disability, many factors impose limits on physical activity.
- Trial name
- NCT06320496
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est
Haematological Cancer, Healthy
Pulsed Electromagnetic Fields in Preventing Physical Deconditioning in Patients Undergoing Prolonged Hospitalization
The goal of this clinical trial is to examine if pulsed electromagnetic fields (PEMF) can prevent or decrease physical deconditioning associated with prolonged hospitalisation and immobility of haematology patients.
- Trial name
- PEMF (NCT06744764)
- Testing
- PEMF (1mT), PEMF (0mT)
- Where
- 2 sites in Singapore
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Sarcopenia in Elderly, Hospital Associated Deconditioning
Preventing Hospital Associated Disability in Older Patients: Individualized Nutrition and Exercise Strategy, a Feasibility Study
Aproximately a third of persons older than 70 years lose physical function and ability to take care of themselves during a stay at a hospital. This is associated to an increased risk of readmission and mortality.
- Conditions
- Sarcopenia in Elderly, Hospital Associated Deconditioning, Malnutrition Elderly, Physical Function
- Trial name
- PrevHAD FS (NCT07124338)
- Testing
- Exercise, supervised
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Bispebjerg Hospital
Covid-19, Deconditioning
Predictors of Recovery and the App-Facilitated Tele-Rehabilitation (AFTER) Program for COVID-19 Survivors
The aim of this study is to investigate the feasibility (safety, adherence) and initial efficacy (physical function and patient reported outcomes) of a multicomponent tele-rehabilitation program during COVID-19 recovery of…
- Trial name
- AFTER (NCT04663945)
- Testing
- Biobehavioral Tele-rehabilitation Sessions
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of Colorado, Denver
Physical Deconditioning
Improving Physical Function in Skilled Nursing Facility Residents
Each year Medicare spends approximately $31.3 billion on 2.4 million skilled nursing facility (SNF) episodes of care. SNFs rely on interdisciplinary approaches to patient care to maximize rehabilitation potential for return to…
- Trial name
- SNF (NCT02421692)
- Testing
- Progressive Rehabilitation
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- University of Colorado, Denver
Physical Deconditioning
Single Maximal Exercise Session and the Metabolic Response of Physically Inactive Young Adults (EASY-Study)
The goal of this clinical trial is to learn how the metabolic parameters of physically inactive young adults respond to a progressive exercise testing.
- Trial name
- EASY (NCT06680713)
- Testing
- Exercise
- Where
- Chile
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Sergio Martinez-Huenchullan
Geriatric, Haematologic Neoplasm
Feasibility of Physical Activity in Older Adults With Haematological Malignancies: ACCES Study
The aim of this study is to implement a simple and unsupervised home-based physical activity (PA) program for cancer patients in 2 oncogeriatric units in Toulouse Hospital (day hospital and week hospital).
- Trial name
- ACCES (NCT06102876)
- Testing
- Physical activity (PA) program
- Where
- France
- Volunteers
- 69 people
- Sponsor
- University Hospital, Toulouse
Heart Defects, Congenital, Adolescent
Rehabilitation of Adolescents and Young Adults With Congenital Heart Diseases
The investigators aim to measure the impact of a rehabilitation program in congenital cardiology in terms of health related quality of life.
- Conditions
- Heart Defects, Congenital, Adolescent, Young Adult
- Trial name
- QUALIREHAB (NCT03690518)
- Testing
- Cardiac rehabilitation
- Where
- 17 sites in France
- Volunteers
- 142 people
- Sponsor
- University Hospital, Montpellier
Advanced Lung Disease, Lung Transplant
Progressive Rehabilitation Therapy in Patients With Advanced Lung Disease
The International Society of Heart and Lung Transplantation Registry data shows that there is a growing population of critically ill patients with advanced lung disease undergoing lung transplantation.
- Conditions
- Advanced Lung Disease, Lung Transplant, Extracorporeal Membrane Oxygenation
- Trial name
- NCT03562728
- Testing
- MRP and NMES(neuromuscular electric stimulation), Standard of Care
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Maryland, Baltimore
Hospital Associated Disability, Immobility
Targeting Muscle Strength Loss Due to Hospitalization in Older Adults by Blood-flow Restriction Combined With an Electromyography-driven Serious Game.
This study investigates a new training method designed to help older adults preserve their muscle strength during hospitalization.
- Conditions
- Hospital Associated Disability, Immobility, Older Adults (65 Years and Older)
- Trial name
- GHOSTLY+ (NCT07294131)
- Testing
- Gamified isometric strength training with blood flow restriction, Standard Physiotherapy
- Where
- 3 sites in Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Deconditioning, Orthopedic Fractures
This Study Aims to Measure the Effect of Acute Hospitalisation on the Physical and Cognitive Functioning of Older Orthopaedic Patients (Aged 65 or Above).
This study aims to investigate the impact of hospitalisation on physical and cognitive performance in patients aged 65 and older admitted with an orthopaedic injury.
- Conditions
- Deconditioning, Orthopedic Fractures, Hospital Associated Deconditioning, Orthopaedic Injuries
- Trial name
- NCT06932224
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- University of Southampton
Aging, Functional Recovery
Advancing Rehabilitation Paradigms for Older Adults in Skilled Nursing Facilities
This cluster randomized clinical trial seeks to provide large-scale, foundational evidence that high-intensity rehabilitation is effective and can be systematically implemented to improve functional outcomes for patients admitted…
- Conditions
- Aging, Functional Recovery, Skilled Nursing Facility, Medically Complex
- Trial name
- NCT05492240
- Testing
- i-STRONGER, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 4,383 people
- Sponsor
- University of Colorado, Denver
Physical Deconditioning
Shifting Rehabilitation Paradigms in Skilled Nursing Facilities
This study seeks to improve rehabilitation methods for restoring physical function with skilled nursing facility care. More specifically, this study is designed to evaluate the effectiveness of an intensive therapeutic…
- Trial name
- NCT02927171
- Testing
- IntenSive Therapeutic Rehabilitation for Older Skilled Nursing Home Residents
- Where
- 3 sites in United States
- Volunteers
- 104 people
- Sponsor
- VA Office of Research and Development
Older Adults, Physical Deconditioning
Progressing Home Health Rehabilitation for Older Adults
This research study explores the effects of a progressive, multi-component intervention following a stay in the hospital or rehabilitation facility.
- Trial name
- NCT02905370
- Testing
- Progressive Multi-Component (PMC), Enhanced Usual Care (EUC)
- Where
- United States
- Volunteers
- 353 people
- Sponsor
- University of Colorado, Denver
Myocardial Injury
Myocardial Physiology And Microanatomy In Individuals Undergoing Heart Surgery
The main focus of the project is to determine to what degree myocardial energy metabolism is linked to impaired function in human cardiomyocytes, whether exercise training and remote ischemic preconditioning can restore…
- Trial name
- TRIMRIPC (NCT01308138)
- Testing
- Exercise training, remote ischemic preconditioning
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Norwegian University of Science and Technology
Immune Thrombocytopenic Purpura
Physical Fitness of Children, Adolescents and Young Adults With Immune Thrombocytopenic Purpura
Patients with chronic immune thrombocytopenic purpura (ITP) live with an anxiety-inducing risk of haemorrhage that is unpredictable over several months or years.
- Trial name
- ITP-CPET (NCT07310342)
- Testing
- IPT-CPET
- Where
- 5 sites in France
- Volunteers
- 53 people
- Sponsor
- University Hospital, Bordeaux