Clinical trials: Physical Disability, active
Blood Loss Anemia, Extracorporeal Membrane Oxygenation Complication
Red Blood Cell Transfusion in ECMO - A Feasibility Trial
Extracorporeal Membrane Oxygenation (ECMO) is an invasive and resource intense treatment used to support critically ill patients who have suffered severe cardiac arrest, cardiac failure or respiratory failure (including severe…
- Conditions
- Blood Loss Anemia, Extracorporeal Membrane Oxygenation Complication, Disability Physical, Cognitive Ability, General
- Trial name
- ROSETTA (NCT05814094)
- Testing
- Red Blood Cell Transfusion
- Where
- 2 sites in Australia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Mucopolysaccharidosis I, Mucopolysaccharidosis II
Study to Evaluate the Safety and Efficacy of Adalimumab in MPS I, II, and VI
Randomized, double-blind, placebo-controlled, parallel-group, single-center study followed by open-label phase, to evaluate the effects of adalimumab compared to placebo on the change from baseline in joint and skeletal disease…
- Conditions
- Mucopolysaccharidosis I, Mucopolysaccharidosis II, Mucopolysaccharidosis VI
- Trial name
- NCT03153319
- Testing
- Adalimumab Injection [Humira], Saline Solution for Injection
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Chronic Neck Pain, Cervical Radiculopathy
Cervical Epidural Block in Chronic Neck Pain
Chronic neck pain can negatively affect daily activities, work ability, and quality of life. Cervical epidural block is commonly used to reduce pain and inflammation, while exercise and physical therapy aim to improve muscle…
- Trial name
- CNP-TREAT (NCT07787741)
- Testing
- Cervical Epidural Steroid Injection, Cervical Stabilization Exercise Program, Physical Therapy Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Alİ Eman, MD
Stroke, Disability Physical
Nurse-led Rehabilitation to Improve Self-care Among Stroke Patients in Bangladesh
Stroke causes various levels of disability, which decreases physical function for a prolonged period. The purpose of this study is to test the feasibility and efficacy of a nurse-led rehabilitation program focused on improving…
- Trial name
- NCT06786559
- Testing
- Assistive Device and health Education
- Volunteers
- 64 people
- Sponsor
- Hiroshima University
Low Back Pain, Disability Physical
Psychological Predictors of Pain and Disability in Patients With Chronic Low Back Pain After Manual Therapy
Low back pain has been reported to cause more disability than any other musculoskeletal health condition worldwide. About eight out of ten people will experience back pain at least once in their lifetime.
- Conditions
- Low Back Pain, Disability Physical, Manual Theapy
- Trial name
- NCT07306312
- Testing
- Manual therapy, Manual therapy plus Pain Neuroscience Education
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- University of Thessaly
Anemia Acute, Fatigue
ABC - A Post Intensive Care Anaemia Management Trial
On discharge from intensive care (ICU) patients are often severely anaemic (have a low level of haemoglobin (Hb) in their red blood cells (RBC)). Anaemia can persist for many months making patients feel tired and fatigued.
- Conditions
- Anemia Acute, Fatigue, Physical Disability, Quality of Life
- Trial name
- NCT04591574
- Testing
- Red Blood Cells (Transfusion)
- Where
- United Kingdom
- Volunteers
- 346 people
- Sponsor
- University of Edinburgh
Low Back Pain
Online Versus Physically Supervised Pilates Exercise Program in Non-specific Low Back Pain
The study will be Randomized Controlled Trial and will be conducted in Riphah Rehabilitation Research Center. The study duration will be 9 months. Non- probability convenient sampling technique will be used to collect the data.
- Trial name
- NCT07026097
- Testing
- Pilates Exercise - Online, Pilates Exercise - Supervised
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Surgery-Complications, Disability Physical
The STRIVE Before Surgery Trial
The STRIVE Before Surgery Trial evaluates patient-reported disability at 90 days after surgery following participating in a home-based multimodal prehabilitation program supported through an online platform.
- Trial name
- STRIVE (NCT06511258)
- Testing
- Prehabilitation
- Where
- Canada
- Volunteers
- 902 people
- Sponsor
- Ottawa Hospital Research Institute
Physial Disabilities
Examining the Health Impact of and Promoting Sitting Light Volleyball in the Greater Bay Area
The present study builds on the promising result of our SLVB pilot study with the aim to extend the works' impact by investigating the effectiveness of a SLVB intervention on the physical and psychological health outcomes in…
- Trial name
- NCT07164508
- Testing
- Sitting Light Volleyball Intervention, Group Seated Dance Intervention
- Where
- Hong Kong
- Volunteers
- 225 people
- Sponsor
- Education University of Hong Kong
Surgery-Complications, Cancer
The PREPARE for Cancer Surgery Study
Our team recently closed recruitment for the PREPARE Trial: PReoperative Exercise to decrease PostoperAtive complication Rates and disability scorEs.
- Conditions
- Surgery-Complications, Cancer, Frailty, Disability Physical
- Trial name
- NCT06503185
- Testing
- Prehabilitation
- Where
- Canada
- Volunteers
- 413 people
- Sponsor
- Ottawa Hospital Research Institute
Neck Pain
Combined Effects of Bruegger's Exercises and Upper Thoracic Mobilizations in Patients With Non-specific Neck Pain
Neck pain is a multifactorial disease, and is a major problem in modern society. Patients with NCNP usually have alterations in cervical proprioception and PS. They may also develop symptoms such as dizziness or vertigo.
- Trial name
- NCT07063004
- Testing
- Bruegger's Exercise and Upper Thoracic Mobilization, Standard Physical Therapy
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University
Chronic Knee Pain, Fibromyalgia
Investigating the Role of Central Pain Hypersensitivity in Skeletal Muscle Neural Drive
Background: pain lasting for 12 weeks or beyond, which is often referred to as chronic pain, is common for people living with musculoskeletal conditions (e.g. arthritis, low back pain and fibromyalgia).
- Trial name
- Pain-Drive (NCT07281651)
- Testing
- Central Pain Hypersensitivity
- Where
- United Kingdom
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Cornelia de Lange Syndrome
Behavioral Assessment and Treatment of Problem Behavior in Children With Cornelia de Lange Syndrome
The goals of this clinical trial are to identify factors associated with the development of problem behavior in Cornelia de Lange syndrome (CdLS) and to develop an effective behavioral assessment and treatment model for problem…
- Trial name
- NCT05829668
- Testing
- ABA-based functional analysis and treatment
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Low Back Pain
Sound Sine Wave And Standard Physiotherapy In Mechanical Low Back Pain
The study design will be a randomized clinical trial (RCT). Sampling technique will be nonprobability convenience sampling. Data will be collected from KKT orthopedic spine center Lahore.
- Trial name
- NCT07026058
- Testing
- Sound Wave Treatment, Standard physiotherapy
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Achilles Tendon Rupture, Physical Disability
Effect of Additional Treatment With NMES After Achilles Tendon Rupture
Increased knowledge is needed about new methods how to treat patients with Achilles tendon ruptures (ATR). A goal is to be able to individualize as well as improve treatment beyond the question about if surgery should be used or…
- Trial name
- NCT06009978
- Testing
- Neuromuscular electrical stimulation (NMES)
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Vastra Gotaland Region
Parkinson Disease, Physical Disability
"Self-Compassion and Self-Efficacy in Parkinson's Disease: Associations With Symptoms, Function, and Quality of Life"
The aim of this study is to evaluate the associations of self-compassion and self-efficacy levels with symptom severity, functional status, and quality of life in individuals with Parkinson's disease.
- Trial name
- NCT07488351
- Testing
- Self-Report Questionnaire Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Acibadem University
Multiple Sclerosis
Longitudinal Assessment of Iron Rims in MS Lesions
In multiple sclerosis (MS), the presence of white matter lesions surrounded by a rim of iron is suggested to signify a more severe disease course.
- Trial name
- NCT05123443
- Testing
- Blood sample provided, 7-T MRI scan
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Type 2 Diabetes (T2DM), Geriatric Syndromes
Using Virtual Reality to Improve Medical Training
As the U.S. population ages, future physicians must be prepared to care for older adults with multiple health conditions and complex needs.
- Conditions
- Type 2 Diabetes (T2DM), Geriatric Syndromes, Disability Hearing, Disability Physical
- Trial name
- NCT07542834
- Testing
- Cinematic Virtual Reality Training, Traditional Didactic Lecture
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ohio University
Implementation Science, Women Health
REmote Virtual Inspiration: Vitality and Energy
REVIVE is a randomized controlled trial designed to evaluate the effects of a remotely delivered seated Tai Chi/Qigong (TCQ) intervention on cardiometabolic health, stress, sleep, and psychological well-being among women with…
- Conditions
- Implementation Science, Women Health, Disability Physical, Meditation
- Trial name
- REVIVE (NCT07675681)
- Testing
- Accesible Tai Chi/Qigong (TCQ), Health Education Videos (HEV)
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- Arizona State University
Mobility Limitation, Physical Disability
Comparison of Two Park-Based Activities on Emotional Well-Being in Adults With Mobility Impairments
This study will examine the impact of a 10-week crossover urban park intervention on the emotional well-being of people with mobility impairments.
- Trial name
- NCT05975476
- Testing
- Physical Activity, Sensory Engagement
- Volunteers
- 10 people
- Sponsor
- University of Alabama at Birmingham