Clinical trials: Physical Exercise Condition
Primary Progressive Multiple Sclerosis (PPMS), Secondary Progressive Multiple Sclerosis (SPMS)
Evaluation of an Online, On Demand Multimodal Wellness Program to Reduce Fatigue and Improve Quality of Life in Progressive Multiple Sclerosis.
The goal of this clinical trial is to learn if an online wellness program can lower fatigue and improve mood and quality of life in people with progressive multiple sclerosis who are 45 to 70 years old and are experiencing…
- Trial name
- DEW (NCT07831928)
- Testing
- Online wellness course and online exercise platform, Usual Care Group
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of Iowa
Mild Cognitive Impairment
Improving Neurological Health With Acetylcholine Via Neuroplasticity-based Computerized Exercise in Mild Cognitive Impairment
This study is a validation study to evaluate efficacy of two neuroplasticity-based, computerized cognitive training programs to improve neurological and neuropsychological health in older adults with mild cognitive impairment…
- Trial name
- INHANCE-MCI (NCT07243600)
- Testing
- Computerized speed-based cognitive training, Computerized executive function cognitive training
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- Posit Science Corporation
Chronic Respiratory Disease
Telemonitoring Physical Activity in Daily Life on Chronic Respiratory Patients
Physical inactivity is a consequence of chronic diseases and on Chronic Obstructive Pulmonary Disease patients is an independent predictor of the risk of hospitalizations and early mortality.
- Trial name
- SmartReab (NCT03930511)
- Testing
- Pulmonary Rehabilitation
- Where
- 2 sites in Portugal
- Volunteers
- 100 people
- Sponsor
- University of Lisbon
Brain Injury, Cerebral Palsy
Home Based Exercise Program for Brain Injury Children
The purpose of this study is to examine whether simple home-base aerobic exercise program have beneficial effect on walking abilities and balance performance in children with brain damage
- Trial name
- NCT00338871
- Testing
- home exercise
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Alyn Pediatric & Adolescent Rehabilitation Hospital
Heart Failure, Systolic
A Novel Home-based Physical Activity Intervention for Stable Chronic Heart Failure Patients
The project focuses on heart failure (HF), a complex clinical syndrome of symptoms and signs that suggest the efficiency of the heart as a pump is impaired. Around 950,000 people in the UK have HF.
- Trial name
- PAHF (NCT03677271)
- Testing
- Physical Activity
- Volunteers
- 20 people
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
NAFLD, Nonalcoholic Fatty Liver Disease
Different Exercise Modalities in the Treatment of NAFLD and Their Impact on Myokines
The goal of this 12-week clinical trial is to investigate the effectiveness of different exercise types in treating Non-Alcoholic Fatty Liver Disease (NAFLD) and to explore their impact on myokine levels associated with lipid…
- Conditions
- NAFLD, Nonalcoholic Fatty Liver Disease, Fatty Liver, Nonalcoholic, Fatty Liver
- Trial name
- NCT06257732
- Testing
- Exercise, Motivational Interviewing
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people
- Sponsor
- Yeditepe University
Spinal Cord Injury
Acute Effect of Ventilatory Support During Exercise in Spinal Cord Injury
The investigators have an existing exercise program (N>70) with a unique population of individuals with spinal cord injury (SCI) who have been enrolled in Functional Electrical Stimulation - Rowing Training (FES-RT) for at least…
- Trial name
- NIV-Ex-CS (NCT03267212)
- Testing
- Non-invasive ventilation(NIV), Functional Electrical Stimulation Row Training (FESRT)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Spaulding Rehabilitation Hospital
Obesity
Telephone Physical Activity Intervention in Obese Youth
The purpose of this study is to examine the effectiveness of a telephone-based physical activity (PA) intervention in obese adolescents attending a Health Weight Comprehensive Clinic.
- Trial name
- TPAI (NCT01162512)
- Testing
- physical activity
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Bone Marrow Transplant Infection, Bronchiolitis Obliterans
Prospective Study of Belated Pulmonary Complications Occurring in Children Treated With Allogeneic Hematopoietic Stem Cells.
Hematopoietic stem cell transplantation (HSCT) is used to treat an expanding array of malignant and non-malignant disorders. This is a prospective multicenter study, in pediatric allo-BMT recipients to analyze the spectrum of…
- Conditions
- Bone Marrow Transplant Infection, Bronchiolitis Obliterans, Chronic Respiratory Insufficiency, Organizing Pneumonia
- Trial name
- RESPPEDHEM (NCT02032381)
- Testing
- late pulmonary complications occurring in children treated with allogeneic hematopoietic stem cells.
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Peripheral Arterial Disease
Influence of Rivaroxaban for Intermittent Claudication and Exercise Tolerance in Patients With Symptomatic PAD
The aim of the conducted research is to evaluate the protective effect of rivaroxaban (trade name of the Xarelto medicinal product), administered together with acetylsalicylic acid (ASA), in comparison with the effectiveness of…
- Trial name
- PAD_RIV_CLI (NCT04305028)
- Testing
- Rivaroxaban, Aspirin
- Volunteers
- 100 people
- Sponsor
- Poznan University of Medical Sciences
Diabetes Mellitus Type 2
Safety, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Multiple Oral Bedtime Doses of ORMD-0801 in Adult Patients With Type 2 Diabetes Mellitus (T2DM)
The purpose of this study is to test the safety and pharmacodynamics of an oral formulation of insulin in subjects with Type 2 Diabetes.
- Trial name
- NCT01889667
- Testing
- ORMD-0801 Dose # 1, ORMD-0801 Dose # 2
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Oramed, Ltd.
Stroke
Attendance and Adherence to Aerobic Exercise After Stroke
Stroke is a common cause of functional impairment and a disease that requires large financial resources and days of care(1). For a few years now, group or individual cardiorespiratory training has been a recommended part of…
- Trial name
- NCT07007507
- Testing
- Aerobic Exercise
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Ostergotland County Council, Sweden
Type 2 Diabetes, Osteoporosis
Impact of Screening and Multicomponent Exercise on Fall Rates, Fractures, and Cardiovascular Health in Diabetes
The DIACTIVE study is a randomized controlled trial with a 5- year follow-up designed to evaluate the impact of comprehensive screening and multicomponent interventions on fall prevention, bone health, nerve function and…
- Conditions
- Type 2 Diabetes, Osteoporosis, Diabetic Neuropathies, Fall Prevention
- Trial name
- DiaACTIVE (NCT06745544)
- Testing
- Rhythm- and Multitask-Based Activity (RYMA) and Activities of Daily Living (ADL)
- Where
- Denmark
- Volunteers
- 490 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Diabetes Mellitus, Type 2, Telemedicine
Mobile Health to Enhance Exercise in Type 2 Diabetes
Being physically active and exercising is important for the treatment of Type 2 diabetes as it helps control blood sugar and improve physical function.
- Conditions
- Diabetes Mellitus, Type 2, Telemedicine, Mobile Applications, Exercise Therapy
- Trial name
- MOTIVATET2D (NCT04653532)
- Testing
- Exercise Programme and Counselling, Polar Ignite and App
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University of British Columbia
Disabilities, Obesity and Overweight
Development of an Inclusive Adaptive Treatment Strategy for Weight Loss in People With Prediabetes Using a Sequential Multiple Assignment Randomized Trial
This is a sub-study to NCT04745572 to include a new cohort of participants with disabilities. This 16-week study will use an experimental approach called the Sequential Multiple Assignment Randomized Trial to help determine which…
- Conditions
- Disabilities, Obesity and Overweight, Prediabetes
- Trial name
- iADAPT (NCT06976307)
- Testing
- High Carbohydrate Diet, Reduced Carbohydrate Diet
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Alabama at Birmingham
Diabetes
Resistance Exercise in Already-active Diabetic Individuals (READI) Trial
The purpose of the READI tiral is to examine the effects of resistance training (weight training) on the blood sugar control of aerobically active individuals with Type 1 Diabetes.
- Trial name
- NCT00410436
- Testing
- Resistance Exercise
- Where
- 3 sites in Canada
- Volunteers
- 131 people
- Sponsor
- Ottawa Hospital Research Institute
Osteoporosis
Bone Development in Adolescent Girls: Effects of Calcium and Exercise
Osteoporosis is a major public health problem. Prevention of osteoporosis depends in part on good bone development in childhood and adolescence.
- Trial name
- NCT00063011
- Testing
- Calcium rich diet, Weight bearing exercise
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Alzheimer Disease, Telerehabilitation
Comparison of the Effect of Online Physical Exercise and Computerized Cognitive Stimulation in Patients With Alzheimer's Disease
Our aim has been determined to investigate the effect of physical exercise alone and in combination with cognitive exercise, on cognitive, physical function and quality of life in individuals with Alzheimer's Disease during the…
- Conditions
- Alzheimer Disease, Telerehabilitation, Online Physical Exercise, Computerized Cognitive Stimulation
- Trial name
- NCT04842734
- Testing
- Physical exercise, Physical exercise and computerized cognitive training
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yeditepe University
Changes in the Intestinal Microbiota Under Hypobaric Hypoxia Conditions, Changes in Blood Glucose Under Hypobaric Hypoxia Conditions
Program Protocol for a Population That Works in Conditions of Hypobaric Hypoxia
The objective of this randomized, longitudinal, single-blind, two-group parallel clinical trial is to evaluate the effect of a physical exercise and nutritional protocol on the health determinants of workers performing their work…
- Conditions
- Changes in the Intestinal Microbiota Under Hypobaric Hypoxia Conditions, Changes in Blood Glucose Under Hypobaric Hypoxia Conditions, Changes in Body Composition Under Hypobaric Hypoxia Conditions, Determination of Physiological Stress in Hypobaric Hypoxia
- Trial name
- NCT07624409
- Testing
- Probiotic Nutritional Intervention, Overload Exercise Protocol, Bioimpedanciometry
- Where
- Chile
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Jorge Torres Mejías
Diabetes, Neuropathy
Improving Autonomic Function and Balance in Diabetic Neuropathy
Type 2 diabetes (DM2) affects nearly 20 million people in the United States while impaired glucose regulation (IGR), which includes impaired glucose tolerance (IGT), impaired fasting glucose (IFG), and early diabetes affects a…
- Conditions
- Diabetes, Neuropathy, Impaired Glucose Tolerance
- Trial name
- IMABIN (NCT01864460)
- Testing
- lifestyle modification
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- VA Office of Research and Development
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