Clinical trials: Physical Fatigue
Fibromyalgia, Chronic Fatigue Syndrome (CFS)
Effect of Physical Exercise and Neuromodulation on Pain, Sleep and Fatigue in Patients With Fibromyalgia
Fibromyalgia (FMS) is a chronic, multifactorial syndrome characterized by widespread pain, fatigue, and cognitive disturbances. This interventional study evaluates the impact of structured physical training using…
- Trial name
- NCT07242573
- Testing
- Physical Training Program, NESA X-Signal, Conventional Physiotherapy
- Where
- Poland
- Volunteers
- 75 people
- Sponsor
- National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland
Metabolic Syndrome, Vascular Disorders
Optimal Timing of Physical Activity in Cancer Treatment
The number of long-term cancer survivors is growing. As a result, treatment-related morbidity - such as cardiovascular disease, metabolic syndrome, functional decline and fatigue - is impacting quality of life and impairing…
- Conditions
- Metabolic Syndrome, Vascular Disorders, Cardiovascular Risk Factors, Fatigue
- Trial name
- ACT (NCT01642680)
- Testing
- A tailored physical activity program during chemotherapy, A tailored physical activity program after chemotherapy
- Where
- Netherlands
- Volunteers
- 266 people
- Sponsor
- University Medical Center Groningen
Sensory Science, Performance Assessment
Personalized Performance Optimization Platform
Crews of future long-duration exploration missions will have to cope with a wide range of stressors that present significant challenges for maintaining optimal performance.
- Conditions
- Sensory Science, Performance Assessment, Countermeasure Evaluation, Neurocognitive Function
- Trial name
- P-POP (NCT06979570)
- Testing
- AttentivU
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Fatigue Syndrome, Chronic
Assessment of Exercise Response in Chronic Fatigue Syndrome / Myalgic Encephalomyelitis.
This study evaluates the correlation between the 6-min walking test (6MWT) with gases measurement, and the peak cardiopulmonary exercise testing (CPET) using incremental cycling with gases and workload measurement, in order to…
- Trial name
- NCT03675087
- Where
- Spain
- Volunteers
- 22 people
- Sponsor
- Escuela Universitaria de Fisioterapia de la Once
Exercise Overtraining, Enjoyment
Interval Training and Cardio-metabolic Health in Overweight/Obese Girls
The main purpose of this study is to compare the impact of 12-week moderate-intensity interval training (MIIT) versus combined MIIT with high-intensity interval training (HIIT) on physical fitness, cardio metabolic, lipidomic…
- Conditions
- Exercise Overtraining, Enjoyment, Cardiometabolic Syndrome, Obesity
- Trial name
- NCT06538714
- Testing
- MIIT, MIIT + HIIT, Control group
- Where
- 2 sites in Tunisia
- Volunteers
- 45 people
- Sponsor
- Association Tunisienne d'Etude & de Recherche sur l'Athérosclérose
Multiple Sclerosis
Rehabilitation in Multiple Sclerosis - Sometimes Too Much?
The primary objective is to evaluate changes in fatigue and physical activity (step counts) before and after rehabilitation in patients with MS (EDSS 3-6.5).
- Trial name
- NCT03187847
- Testing
- Actigraph GT3X
- Where
- Switzerland
- Volunteers
- 28 people
- Sponsor
- Klinik Valens
Fibromyalgia, Chronic Fatigue Syndrome
Effectiveness and Health Benefits of a Nutritional, Chronobiological and Physical Exercise Intervention in Fibromyalgia and Chronic Fatigue Syndrome (SYNCHRONIZE +)
Chronic pain, fatigue and insomnia are classical symptoms of Fibromyalgia and Chronic Fatigue Syndrome, affecting seriously life quality. Non-pharmacological multicomponent approach is gaining relevance in Fibromyalgia treatment.
- Trial name
- SYNCHRONIZE + (NCT05719493)
- Testing
- multicomponent treatment
- Where
- Spain
- Volunteers
- 86 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Liver Transplantation (LT), End-Stage Liver Disease
Physical and Cognitive Outcomes After Post-Transplant Physiotherapy in Liver Transplant Recipients
Liver transplantation is the most effective treatment for end-stage liver disease. However, many recipients continue to experience problems such as reduced physical function, impaired balance, fatigue, and cognitive difficulties…
- Trial name
- NCT07694245
- Testing
- Routine Post-Transplant Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people
- Sponsor
- Hasan Kalyoncu University
Exercise-Induced Upper Extremity Fatigue, Hand-Eye Coordination
Neural Mobilization After Upper Extremity Fatigue in Amateur Athletes
This randomized controlled trial evaluated the acute effects of neural mobilization and dynamic stretching after upper extremity fatigue on upper extremity performance and hand-eye coordination in amateur athletes.
- Conditions
- Exercise-Induced Upper Extremity Fatigue, Hand-Eye Coordination, Athletic Performance
- Trial name
- NCT07682103
- Testing
- Neural Mobilization, Dynamic Stretching
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Uludag University
Hypertension, Elevated Blood Pressure
Blood Pressure Following Isometric Exercise in Inactive Adults
This study investigates how isometric exercise training (IET) affects blood pressure in physically inactive adults. Isometric exercise involves sustained muscle contractions without movement-for example, pushing against a fixed…
- Conditions
- Hypertension, Elevated Blood Pressure, Sedentary Lifestlye
- Trial name
- BELIEF-BP (NCT06937164)
- Testing
- Isometric Exercise Training (IET), Expectation-Enhancing Informational Framing
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Canterbury Christ Church University
Multiple Sclerosis, Gait Disorders, Neurologic
"Balance, Gait, and Motion Analysis in Multiple Sclerosis"
The goal of this observational cross-sectional study is to investigate the relationship between functional measures of balance and gait and objective kinetic and kinematic parameters in people with Multiple Sclerosis (MS).
- Conditions
- Multiple Sclerosis, Gait Disorders, Neurologic, Postural Balance, Motion Analysis
- Trial name
- MS-BALGAIT (NCT07630311)
- Where
- 2 sites in Greece
- Volunteers
- 40 people
- Sponsor
- University of Patras
Life Stress, Fatigue
Multicentre, Double-blind Study Versus Placebo on Impact and Safety of Extramel® 140 IU on Perceived Stress, Physical and Intellectual Fatigue, Pain Perception if Present, and the Impact on the Quality of Life
Objectives of this Multicentre, double-blind study versus placebo were to evaluate impact and safety of the daily administration of Extramel® 140 IU SOD for 12 weeks on perceived stress, physical and intellectual fatigue, pain…
- Conditions
- Life Stress, Fatigue, Pain, Quality of Life
- Trial name
- Ex Stress II (NCT01767922)
- Testing
- Extramel 10 mg - 140 UI SOD
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Robertet SA
Covid19
Evaluation of Muscle Strength, Functional Independence, Myalgia, Fatigue and Dyspnea in COVID-19 Infection
Coronavirus disease 2019 (COVID-19) is a serious, acute infectious disease caused by Serious Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). COVID-19 can manifest itself in a wide variety of clinical scenarios.
- Trial name
- NCT04784546
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Gazi University
Quiet Quitting, Fatigue, Compassion
Physical Fatigue, Compassion Fatigue, and Quiet Quitting in Physiotherapists
Physiotherapists are exposed to both physical and emotional demands due to the nature of their profession. Repetitive physical workload, prolonged standing, patient handling, and continuous interaction with patients may…
- Conditions
- Quiet Quitting, Fatigue, Compassion, Work Engagement
- Trial name
- NCT07340866
- Testing
- No Intervention (Observational Study)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Healthy
Mental and Physical Well-Being of Frontline Health Care Workers During Coronavirus Disease 2019 (COVID-19)
Study to support the mental and physical well-being of US health care workers during the COVID-19 pandemic and ensure high-quality care for patients through Stress First Aid.
- Trial name
- COVER-HCW (NCT04723576)
- Testing
- Stress First Aid
- Where
- 2 sites in United States
- Volunteers
- 7,444 people, healthy volunteers welcome
- Sponsor
- RAND
COVID-19 Pneumonia, Pain
Pain, Fatigue and Life Quality in COVID-19 Patients
The aim in this study is to evaluate pain, fatigue and quality of life in patients with Covid-19 pneumonia in long-term follow-up and to investigate their relationship with pneumonia severity, age, presence of comorbidity and…
- Conditions
- COVID-19 Pneumonia, Pain, Fatigue, Quality of Life
- Trial name
- NCT04988126
- Testing
- Interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Afyonkarahisar Health Sciences University
Locomotive Syndrome
Geriatric Locomotive Syndrome and Related Factors in Older Adults
It has been stated that the results of physical function and physical performance affecting locomotive syndrome in elderly individuals are controversial and studies are still needed.
- Trial name
- NCT06300632
- Testing
- geriatric locomotive syndrome
- Where
- Turkey (Türkiye)
- Volunteers
- 97 people
- Sponsor
- Kırıkkale University
Head and Neck Cancer
Validity and Reliability of Outcome Measures in Patients With Cancer of the Head and Neck
The purpose of this study is to establish the Six-Minute Walk Test, 10-Meter Walk Test, 30 Second Chair Stand, Linear Analog Scale of Function, and the Modifed Brief Fatigue Inventory as reliable and valid outcome measurements…
- Trial name
- NCT01952821
- Testing
- Six-Minute Walk Test, 10-Meter Walk Test, 30-Second Chair Stand
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Mayo Clinic
Fatigue, Physical Activity
Lupus Intervention for Fatigue Trial
Participants in the Chicago Lupus Database or individuals seen at Northwestern Medicine will be approached to enroll in a one year clinical trial looking at decreasing fatigue in persons with systemic lupus erythematosus (SLE).
- Conditions
- Fatigue, Physical Activity, Lupus Erythematosus, Systemic
- Trial name
- LIFT (NCT02653287)
- Testing
- Experimental, Control
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Northwestern University
Fatigue
The Effects of Adding a Home Exercise Program to a Clinical Physical Therapy Program on Cancer-Related Fatigue
The purpose of this study is to find out if adding a home exercise program to a clinic physical therapy program will improve the fatigue experienced by patients being treated with concurrent chemotherapy and radiation therapy for…
- Trial name
- NCT00840554
- Testing
- Clinic-based physical therapy program., Home exercise program.
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Florida