Clinical trials: Physical Frailty
Cardiac Infarct, Cardiac Valve Disease
Frailty, Physical Capacity and Lung Function in Postoperative Cardiac Surgery Patients
The goal of this observational and prospective study is to investigate changes in physical performance, lung function, and respiratory and peripheral muscle strength in patients during the postoperative period following coronary…
- Conditions
- Cardiac Infarct, Cardiac Valve Disease, Fragility, Physical Disability
- Trial name
- NCT06247358
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- University of Sao Paulo General Hospital
Aged 60 Years or Older
Life Monitoring for Rural Older Adults
Aging is a biological process that is accompanied by a progressive deterioration of physical and mental abilities and leads to an increased risk of disease.
- Trial name
- VIVIR (NCT06974006)
- Testing
- Devices: Kardia Mobile 6L; Omron M7 BP ; Beurer PO30; Datospir Peak-10; NUTRILAB BIA 101 BIVA® PRO; JAMAR® Smart.
- Where
- 2 sites in Spain
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- European University Miguel de Cervantes
Physical Frailty, Physical Disability
Multidomain Intervention to Prevent Disability in Elders
Prevention of physical disability represents a major priority for the public health system. Physical disability is the final result of a complex cascade of negative events occurring at different levels (i.e., environmental…
- Conditions
- Physical Frailty, Physical Disability, Mobility Disability
- Trial name
- MINDED (NCT02082171)
- Testing
- Multidomain intervention
- Where
- France
- Volunteers
- 210 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Pre-frail, Elderly
Clinical and Economic Assessment of a Pre-frail Screening Program
The study intervention improves functional capacity and delays frailty status in pre-frail elderly subjects.
- Trial name
- NCT02138968
- Testing
- Multidisciplinary intervention
- Where
- Spain
- Volunteers
- 170 people
- Sponsor
- Consorci Sanitari del Maresme
Toileting Disability, Functional Urinary Incontinence
Defeating Urinary Incontinence With Exercise Training (DUET) Feasibility Study
Pilot study to determine the feasibility and possible treatment effect of a multi-component intervention combining non-drug treatments for urinary incontinence and physical activity to improve urinary incontinence, toileting…
- Trial name
- DUET (NCT02206958)
- Testing
- Defeating Urinary Incontinence with Exercise Training
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Minnesota
Frail Elderly
Frailty Prevention Through Improvement of Nutrition Physical Activity and Social Participation
The life expectancy of the Taiwanese reached 75.98 years in males and 82.65 years in females in 2011. Because of the improved longevity and low birth rate, proportion of elderly population increased to 11.15% in our society.
- Trial name
- FPINPS (NCT03477097)
- Testing
- Nutrition, exercise and social network intervention
- Where
- Taiwan
- Volunteers
- 319 people
- Sponsor
- Academia Sinica, Taiwan
Frailty
Pilot-testing the Effect of Magnetic Mitohormesis Therapy for Treating Frailty in Older Adults
Thirty (30) adults with limited physical function will be recruited to participate in a double-blind pilot randomized controlled crossover trial in which all participants will receive 12-weeks of twice weekly MMT treatment in the…
- Trial name
- NCT05930470
- Testing
- Magnetic Mitohormesis Therapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Auburn University
Frailty, Aging
Effect of Multicomponent Exercises VIVIFRAIL® in Older Adults
This study employs a randomized, controlled, paired, single-blind clinical trial design. The targeted demographic comprises individuals aged 60 and above.
- Conditions
- Frailty, Aging, Physical Disability
- Trial name
- NCT06271239
- Testing
- Intervention group (ViviFrail), Group Suggestions for a Healthy Life (CG)
- Where
- 4 sites in Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Frailty, Aging
Vivifrail Exercise Program in Nonagenarians: Effects on Function, Muscle, and Cognition
This randomized clinical trial investigates the effects of a home-based multicomponent exercise program (Vivifrail) on physical function, muscle morphology, and cognition in community-dwelling adults aged 90 years and older.
- Conditions
- Frailty, Aging, Cognitive Decline
- Trial name
- Vivifrail (NCT07731529)
- Testing
- Vivifrail multicomponent exercise program
- Where
- 2 sites in Brazil
- Volunteers
- 54 people
- Sponsor
- Federal University of Rio Grande do Sul
Frailty, Physical Disability
Vitamin D and Calcium Supplementation at Danish Nursing Homes
Nursing home residents are in high risk of vitamin D deficiency, which negatively affects bone health. Vitamin D and calcium supplements have shown to increase bone density and reduce fracture risk and may affect daily physical…
- Conditions
- Frailty, Physical Disability, Aging, Muscle Weakness
- Trial name
- NCT04956705
- Testing
- Vitamin D and calcium
- Where
- 2 sites in Denmark
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University College Copenhagen
Frailty, Comorbidities and Coexisting Conditions
Frailty in Outpatient Digestive Endoscopy
The increase in our society of the proportion of frail people who suffer from disability and dependency forces us to detect modifiable factors and therefore subject to intervention that can adapt health care for frail patients in…
- Conditions
- Frailty, Comorbidities and Coexisting Conditions, Complication
- Trial name
- FRIEND (NCT06507527)
- Testing
- Collection of variables
- Where
- Spain
- Volunteers
- 1,474 people
- Sponsor
- Parc de Salut Mar
Sarcopenic Obesity, Frailty
Multicomponent Analysis of phYsical Frailty BiomarkErs: Focus on Mitochondrial Health - MAYBE
The study will be conducted in a group of obese sarcopenic patients (Sarco-Ob) aged > 60 years on moderately hypocaloric diet therapy aimed at comparing the effect of a strength exercise protocol, combined or not with dietary…
- Conditions
- Sarcopenic Obesity, Frailty, Malnutrition; Protein
- Trial name
- MAYBE (NCT05938205)
- Testing
- AA-1, AA-2, Exe-H
- Where
- Italy
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Frailty, Mild Cognitive Impairment
Influence of Square-stepping Exercise on Brain Activation, Cognitive Function and Physical Performance in Frail Elders With MCI
This study is to elucidate the possible mechanisms of SSE by examining brain activation differences between SSE patterns and usual walking, as well as the relationship between brain activity and SSE performance, between cognitive…
- Trial name
- NCT05173363
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- National Yang Ming Chiao Tung University
Frailty
Feasibility of a Multidisciplinary Student-Led Program to Improve Frailty in Nursing Home Residents
BACKGROUND Frailty, regarded as a potentially reversible process and defined as a progressive deterioration of physiological systems and intrinsic capacity, constitutes a key risk factor for disability, dependency and…
- Trial name
- CUIDAFRAIL (NCT07182747)
- Testing
- Nursing students' intervention programme, Standard care from Public Andalusian Health Service
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Universidad de Almeria
Cancer
Assessment of Frailty in Elderly Patients With Advanced Cancers
This study is looking at the feasibility of performing frailty assessments on elderly patients with advanced cancers
- Trial name
- FAC-C (NCT02482285)
- Where
- United Kingdom
- Volunteers
- 8 people
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
Aortic Stenosis
Frailty and Mortality in Older Old With Severe Aortic Stenosis
BACKGROUND.- The frailty syndrome (FS) associates an increase in morbidity and mortality in the elderly patient. When severe and symptomatic, aortic stenosis (AS) is a disease with poor prognosis, the most frequent cause of heart…
- Trial name
- SAS-frailty (NCT02745314)
- Testing
- Frailty measurement, Comprehensive Geriatric Assessment
- Where
- Spain
- Volunteers
- 605 people
- Sponsor
- Hospital de Meixoeiro
Aging, Heart Failure With Preserved Ejection Fraction
Novel Respiratory Training as Part of Palliative Care for Older Adults With Heart Failure
In a randomized controlled trial, to study the utility of inspiratory muscle training (IMT) to improve functional outcomes in adults aged ≥70 years with heart failure (HF) who have been referred to palliative care for end-stage…
- Conditions
- Aging, Heart Failure With Preserved Ejection Fraction, Heart Failure With Reduced Ejection Fraction, Frailty
- Trial name
- RETRO (NCT06576297)
- Testing
- Inspiratory Muscle Training (IMT), Standard of Care
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pittsburgh
Exercise, Frailty
Evaluation of the Walk With Ease Program for Fall Prevention
The study will use a randomized controlled trial design to evaluate the potential of incorporating physical therapy exercises (primary prevention strategy) within an evidence-based intervention called Walk with Ease to reduce…
- Conditions
- Exercise, Frailty, Arthritis, Accidental Falls
- Trial name
- NCT05693025
- Testing
- Group Exercise, Behavioral Training
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Iowa State University
Patients Over 75 Years Old With a Cancer Discovery
Assessment of Positron Emission Tomography to Early Detect Frailty in Onco-geriatry
Oncogeriatric frailty assessment is a multifactorial approach to determine the most appropriate treatment for the health status of elderly cancer patients and this assessment is recommended for patients over 75 years of age.
- Trial name
- FOGTEP (NCT03370809)
- Testing
- Brain PET/CT step
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Central Hospital, Nancy, France
Coronary Artery Disease, Sedentary Behavior
Sedentary Behavior Intervention for Older Adults With Coronary Heart Disease and Frailty
This study aims to evaluate the feasibility and effectiveness of a sedentary behavior intervention based on the Integrated Theory of Health Behavior Change (ITHBC) in older adults with coronary heart disease and frailty.
- Conditions
- Coronary Artery Disease, Sedentary Behavior, Prefrailty
- Trial name
- NCT07762898
- Testing
- ITHBC-Based Sedentary Behavior Intervention
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Gansu University of Chinese Medicine