Clinical trials: Physical Frailty
Frailty
Feasibility and Effectiveness of Concurrent Exercise Training on Frail Older Adults Living in Nursing Homes
The present study is a crossover randomized controlled trial that aims to investigate the effects of concurrent exercise training over usual care on physical performance, muscle strength, and myokines concentrations in frail…
- Trial name
- NCT06380127
- Testing
- Exercise training
- Where
- Portugal
- Volunteers
- 46 people
- Sponsor
- Universidade do Porto
Kidney Injury, Acute
A Machine Learning Prediction Model for Postoperative Acute Kidney Injury in Non-Cardiac Surgery Patients
Primary objectives of this study is to develop and validate a predictive model for acute kidney injury after non-cardiac surgery based on machine learning.
- Trial name
- NCT07030166
- Testing
- No intervention measures were used.
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Lanyue Zhu
Frailty, Sarcopenia
Neuromuscular and Multi-Omics Synergy of Combined Creatine × HMB Supplementation Plus Exercise to Improve Muscle Function in Sarcopenic Frailty
Sarcopenia and physical frailty are highly prevalent among institutionalized older adults and are major contributors to functional decline, reduced mobility, and loss of independence.
- Conditions
- Frailty, Sarcopenia, Aging, Malnutrition Elderly
- Trial name
- MULTI-FRAIL (NCT07275996)
- Testing
- Creatine Monohydrate, Multicomponent Exercise Program, β-Hydroxy-β-Methylbutyrate (HMB)
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Universidad de Burgos
Frailty
Home-based Empowerment Through Physical Exercise Assisted by Technology for Frail Patients
This project, that lays in Health Ageing mission promoted by European Commission, aims to address the issue of frailty, a condition that poses the elderlies to increased vulnerability, deconditioning, and, ultimately, loss of…
- Trial name
- ARTIDE (NCT07118761)
- Testing
- Home-based walking training
- Where
- 2 sites in Italy, Spain
- Volunteers
- 120 people
- Sponsor
- University Hospital of Ferrara
Post Intensive Care Syndrome
Impact of Frailty and ICU-AW on Post-ICU Fatigue Self-reported
After a prolonged stay in Intensive Care Unit (ICU), fatigue is the most common symptom reported by patients in the Post Intensive Care Syndrome (PICS).
- Trial name
- FICUF (NCT05984069)
- Testing
- observational prospective data collection
- Where
- 2 sites in France
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Fragility, Sarcopenia
Efficacy of an Intervention to Prevent Frailty in Obese Elderly People (PRE-FROB)
Rationale: There is increasing evidence that obesity may be a risk factor for frailty in the elderly. Obesity favors a state of chronic inflammation and insulin resistance, involves a fatty infiltration of the muscle and an…
- Conditions
- Fragility, Sarcopenia, Obese, Elderly
- Trial name
- PRE-FROB (NCT03000907)
- Testing
- Intervention
- Where
- Spain
- Volunteers
- 319 people
- Sponsor
- Consorci Sanitari del Maresme
Psychological Health, Physical Health
Dynamic Predictions of the Links Between Psychological and Physical Health of Older Patients in Nursing Home
Taking the older person as a whole is now essential to age well and prevent loss of functional independence. However, the relationship between physical and mental health remains not well understood.
- Trial name
- BioMIND (NCT05729906)
- Testing
- psychological and physical tests
- Where
- 5 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Tours
Frail Elderly Syndrome, Mood
FOCUS Guidelines and Adherence to Physical Activity in Ageing Women.
The study aimed at assessing whether the guidelines from the European project FOCUS had an effect on adherence to a physical activity program in older women.
- Conditions
- Frail Elderly Syndrome, Mood, Quality of Life, Cognitive Decline
- Trial name
- NCT03981965
- Testing
- Physical activity
- Where
- Spain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Frailty, Dementia
Multicomponent Exercise Program on Physical Function, Cognition and Falls Risk Among Older Adults Living in Nursing Homes (MOVE4CARE)
Can a multicomponent exercise program significantly improve physical and cognitive function and reduce fall rates among nursing home residents? To address this question, the present study aims to compare the effectiveness of a…
- Trial name
- MOVE4CARE (NCT07392944)
- Testing
- Multicomponent exercise intervention, stretching and relaxation program
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Frailty
Effect of an Exercise Program for Frail Older Adults
Despite the high level of evidence for physical activity as a countermeasure for frailty, the current Flemish standard of care does not include structural PA interventions for community-dwelling frail older adults.
- Trial name
- AA@HOME (NCT05946109)
- Testing
- ACTIVE-AGE@home
- Where
- Belgium
- Volunteers
- 195 people
- Sponsor
- Universitair Ziekenhuis Brussel
Gastrointestinal Disease, Frail Elderly Syndrome
Frailty Assessment of Patients With Gastrointestinal Surgery
Patients aged 65 or older under gastrointestinal surgery will be enrolled，the investigators will assess the frailty of these patients by Frailty Index Scale and explore the correlation between the frailty and perioperative…
- Trial name
- NCT03930082
- Testing
- Frailty Index Scale
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Ziqiang Wang,MD
Central Nervous System Neoplasm, Hodgkin Lymphoma
Mobility and Physical Activity in Adolescent and Young Adult Cancer Patients or Survivors at Risk for Cardiovascular Morbidity and Frailty, The MOBILE AYA Study
This study attempts to learn more about the activity levels of adolescent and young adult (AYA) cancer patients or survivors at risk for cardiovascular morbidity and frailty by using a smartphone application called Beiwe.
- Conditions
- Central Nervous System Neoplasm, Hodgkin Lymphoma, Malignant Solid Neoplasm, Non-Hodgkin Lymphoma
- Trial name
- NCT05169151
- Testing
- Smartphone Application
- Where
- United States
- Sponsor
- M.D. Anderson Cancer Center
Frailty, Disability Physical
Prevention of Functional and Cognitive Impairment Through a Multicomponent Exercise Program
The hospitalized elderly patient is conditioned by a series of circumstances unrelated to the pathological process itself that caused hospital admission and that usually worsen the results of hospitalization.
- Conditions
- Frailty, Disability Physical, Hospital Acquired Condition
- Trial name
- NCT04600453
- Testing
- Physical Exercise
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Fundacion Miguel Servet
Frailty at Older Adults, Post-Traumatic Stress Disorder in Old Age
Multimodal Intervention for Older Adults After an Earthquake
This randomized controlled study was conducted among older adults (≥65 years) living in temporary container housing in Kahramanmaraş after the February 2023 earthquakes.
- Conditions
- Frailty at Older Adults, Post-Traumatic Stress Disorder in Old Age, Depression in Adults, Malnutrition Elderly
- Trial name
- NCT07273253
- Testing
- Multimodal intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Frailty, Muscle Power
Effects of Resistance Training in Centenarians
This study is a multicenter intervention evaluating the effectiveness and safety of resistance training in institutionalized centenarians.
- Conditions
- Frailty, Muscle Power, Old and Very Old People, Cognitive Abilities
- Trial name
- NCT07118423
- Testing
- Exercise
- Where
- Spain
- Volunteers
- 19 people
- Sponsor
- Universidad de Zaragoza
Ageing, Frailty
Comprehensive Geriatric Assessment in the Elderly Subjects (PROMISING)
The primary objective of this observational study is to verify, through a comprehensive geriatric assessment, the health status of a sample of elderly subjects.
- Trial name
- PROMISING (NCT05822154)
- Testing
- comprehensive geriatric assessment
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Istituto Nazionale di Ricovero e Cura per Anziani
Frailty in Aging, Emergency Department Visit
Patient Experience of CFS-assessment in the ED
An increasingly common subject of interest among emergency care research is frailty, which is commonly described as a decline in several inter-related physiological systems, in addition to an increased vulnerability to stressors.
- Conditions
- Frailty in Aging, Emergency Department Visit, Patient Experience, Qualitative Research
- Trial name
- NCT06621290
- Testing
- Semi-structured interviews
- Where
- Sweden
- Volunteers
- 21 people
- Sponsor
- University Hospital, Linkoeping
Solid Carcinoma, Frailty
Geriatric Oncology Screening of Older Patients With Solid Cancers
Older patients with cancer constitute a heterogeneous group with varying comorbidity; therefore, geriatric assessment with initial screening is recommended. The Geriatric 8 (G8) has been established as a promising screening tool.
- Conditions
- Solid Carcinoma, Frailty, Age, Geriatrics
- Trial name
- PROGNOSIS-G8 (NCT04644874)
- Testing
- Geriatric 8, modified Geriatric 8, 30 second chair stand test
- Where
- Denmark
- Volunteers
- 1,401 people
- Sponsor
- Odense University Hospital
Frail Elderly, Elderly
Fine-tuned Physical Training to Improve Quality of Life in Older Individuals
The overall aim of this project, which is based upon the interdisciplinary expertise of four research groups within the University of Rome Foro Italico, in the macro-areas of psychology, bioengineering, physiology, and internal…
- Conditions
- Frail Elderly, Elderly, Aging, Aging Frailty
- Trial name
- NCT07546734
- Testing
- Resistance Training (RT), Resistance training + CORE (RT+CORE), CMDT training
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- University of Rome Foro Italico
Cognitive Frailty, Physical Frailty
Cognitive Impairment in Older Emergency Department Users and Associated Adverse Outcomes
This study examines the prevalence and incidence of older ER users with cognitive impairment (i.e., dementia and/or delirium) using the ER2 item temporal disorientation in older ED users who are participants of the ER2 cohort…
- Conditions
- Cognitive Frailty, Physical Frailty, Older Emergency Department Users
- Trial name
- NCT04235738
- Testing
- Observational
- Where
- Canada
- Volunteers
- 4,724 people
- Sponsor
- Jewish General Hospital