Clinical trials: Physical Frailty
Stroke, Frailty
Multimodal Assessment of Frailty in Acute Stroke Patients
The goal of this study is to investigate the influence of frailty on clinical and stroke characteristics, treatment and outcomes in patients with acute stroke. The main questions it aims to answer are: 1.
- Trial name
- MAFASP (NCT06031909)
- Testing
- Multimodal frailty assessment
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University of Giessen
Critical Illness, Sarcopenia
Effects of Frailty, Sarcopenia and Muscle Wasting on Outcomes of Patients in the Surgical Intensive Care Unit
The primary aim of the study is to evaluate consequences of frailty in critically ill patients. We hypothesize that a higher frailty index (based on published questionnaires) predicts a longer surgical intensive care unit and…
- Conditions
- Critical Illness, Sarcopenia, Muscle Wasting
- Trial name
- NCT02270502
- Testing
- Ultrasound Philips CX50, Frailty Index Questionnaire, Muscle strength tests
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- Massachusetts General Hospital
Older Adults
Flexi-Bar and Multi-Component Exercises
Background: Previous studies have suggested that both Flexi-Bar and Multi-Component exercises can improve an individual's physical fitness and musculoskeletal discomfort.
- Trial name
- NCT05025137
- Testing
- Flexi-Bar Exercise, Multi-Component exercise
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yang Shang-Yu
Social Isolation, Chronic Disease
Physical Rehabilitation Intervention With Protein Supplementation for People With Problematic Substance Use and Homelessness
Background: People who are homeless are more likely to experience poor mental health and addiction as well as suffering from non-communicable diseases.
- Conditions
- Social Isolation, Chronic Disease, Physical Disability, Addiction
- Trial name
- NCT05700305
- Testing
- 12-week, low threshold physical rehabilitation intervention with protein supplementation
- Where
- Ireland
- Volunteers
- 45 people
- Sponsor
- University of Dublin, Trinity College
Physical Disability
Multi-ingredient Nutrition Supplement in Older Adults
The aims of the present study are: i. To conduct a population study of body composition, muscle function and ability to undertake activities of daily living in elderly Irish individuals ii.
- Trial name
- NCT02001831
- Testing
- Supplement
- Where
- Ireland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Heart Failure, Old Age; Debility
The Effects of an Exercise Programme for Older Patients With Heart Failure
Patients with heart failure have decreased exercise tolerance, balance problems, and fall risks. The purpose of this research was to investigate the effect of an exercise program based on the Empowerment Model for participants…
- Trial name
- NCT04022369
- Testing
- Exercise Group
- Volunteers
- 21 people
- Sponsor
- Emine Karaman
Aging, Functional Status
Remote Physical and Cognitive Training Effects in Older Adults at Increased Risk of Clinical-functional Vulnerability
This study is a randomized, single-blind, parallel, controlled, superiority trial. The main objective is to verify the chronic effects of a remote 12-week low-intensity physical training program alone or in combination with…
- Trial name
- NCT05309278
- Testing
- Physical training, Cognitive training
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Frailty, Frailty At Older Adults
ASSESSMENT of FRAILTY AS a PROGNOSTIC FACTOR for MORTALITY, DISABILITY, and QUALITY of LIFE AFTER ICU ADMISSION
Between 30% and 40% of elderly patients (over 70 years old) who require hospitalization and treatment in Intensive Care Units (ICU) exhibit a state of frailty.
- Trial name
- FG-UCI (NCT06793462)
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Renal Insufficiency,Chronic, Dietary Intake Patterns
Strategies for Proactive Health in People With Kidney Function Decline
This prospective cohort study aims to investigate how kidney function decline affects multiple body systems and how personalized nutrition can help maintain health and slow disease progression.
- Conditions
- Renal Insufficiency,Chronic, Dietary Intake Patterns, Malnutrition, Frailty
- Trial name
- NCT07245186
- Where
- China
- Volunteers
- 1,800 people
- Sponsor
- Huashan Hospital
Physical Frailty
Protein and Exercise to Counteract Frailty in Older Adults
The purpose of this study is to determine the effects of interventions with high-protein diet alone or in combination with resistance training on muscle mechanical function (muscle power and strength), frailty status, functional…
- Trial name
- NCT03842579
- Testing
- Resistance training, High-protein diet, Recommendations
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- University of Southern Denmark
Frailty
Psychometric Properties of the Elderly Health Questionnaire Among Community-dwelling Older People
The aims of this study are to validate the reliability and validity of Elderly Health Questionnaire in assessing frailty risk of community-dwelling older adults.
- Trial name
- NCT04166123
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
End-stage Liver Disease, Liver Cirrhosis
Nutrition and Exercise Prehabilitation in Patients Awaiting Liver Transplantation
This study aims to evaluate the effects of a diet with even protein distribution plus exercise (Group A) versus a diet with skewed protein distribution plus exercise (Group B) versus standard dietary and physical activity advice…
- Conditions
- End-stage Liver Disease, Liver Cirrhosis, Liver Transplantation, Malnutrition
- Trial name
- POWER-LT (NCT07561138)
- Testing
- Diet with even protein distribution plus exercise program, Diet with skewed protein distribution plus exercise program, Standard dietary and physical activity advice
- Where
- 2 sites in Greece
- Volunteers
- 90 people
- Sponsor
- Kalliopi Anna Poulia
Frailty at Older Adults, Mastication
Oral Function Intervention in Community-Dwelling Older Adults
Oral frailty is a potentially reversible condition associated with physical frailty and functional decline in older adults. Interventions targeting oral function may therefore improve broader physical health.
- Conditions
- Frailty at Older Adults, Mastication, Physical Functional Performance, Aging
- Trial name
- NCT07866781
- Testing
- Integrated Oral Function Intervention
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Frailty
The Application of the Transtheoretical Model to the Frailty Elderly in the Community
As the age structure shows an aging population while facing physical and mental changes among the frailty of the community elderly.
- Trial name
- NCT05242549
- Testing
- Fitness and Nutrition Program for Seniors
- Where
- Taiwan
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Old Age, Frailty
Activity and Health in Nursing Homes
There is expected to be an increased need for full time nursing homes as the increase in number of older adults increases and the rate of dementia diagnosis happens simultaneous with the decrees of healthcare personnel the years…
- Trial name
- NCT05037084
- Testing
- no intervention
- Where
- Norway
- Volunteers
- 1,123 people
- Sponsor
- Norwegian University of Science and Technology
TAVI(Transcatheter Aortic Valve Implantation), TAVI
Quality of Life Improvement After TAVI (QualiTAVI-UK Trial)
Transcatheter aortic valve implantation (TAVI) has become an important therapeutic intervention for patients with symptomatic severe aortic stenosis (AS) who are at high surgical risk.
- Conditions
- TAVI(Transcatheter Aortic Valve Implantation), TAVI, Quality of Life, Mental Health
- Trial name
- QualiTAVI-UK (NCT07193004)
- Testing
- Quality of Life
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University Hospital Plymouth NHS Trust
Cancer, Frailty
G8 Screening Tool Validation in Older Adults With Cancer in Portugal
The G8 screening tool is widely recommended for the identification of frailty in older adults with cancer. However, prospective validation data in the Portuguese population are currently lacking.
- Conditions
- Cancer, Frailty, Aged
- Trial name
- G8-PT (NCT07487298)
- Testing
- G8 Screening Tool, Comprehensive Geriatric Assessment
- Where
- Portugal
- Volunteers
- 150 people
- Sponsor
- Hospital de Braga
Healthy Volunteers
Screening for Frailty at Home
"Many tools to evaluate frailty have been developed. However, at the time our study was designed, none of these instruments had been validated in terms of psychometric properties.
- Trial name
- SEGAm (NCT02852200)
- Testing
- SEGAm
- Where
- France
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Frailty, Sarcopenia
Promoting Autonomy Through ExerCisE (PACE) in Outpatient Geriatric Clinics
Physical inactivity is highly prevalent among older adults and is associated with declines in physical function, independence, quality of life, and social participation.
- Trial name
- PACE - OGC (NCT07787663)
- Testing
- PACE
- Where
- Canada
- Volunteers
- 162 people
- Sponsor
- Université du Québec a Montréal
Cognition Disorders in Old Age, Cognitive Function
Impact of Nutrition, Sleep, and Physical Activity on Intellectual Function and Muscle Mass in Older Adults
The goal of this prospective, single site, interventional randomized control trial is to treat age related health conditions in adults older than 65 years and functional independence.
- Conditions
- Cognition Disorders in Old Age, Cognitive Function, Frailty/Sarcopenia, MCI
- Trial name
- INSPIOR (NCT06135740)
- Testing
- Fitbit wearing, with notification for sleep, activity and nutrition based fitbit data, Routine care
- Where
- Japan
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- Tokyo University